Bicalutamide

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 12)
1 2 3 4 5 6 7 8 9 10
Angioedema def Angioedema def postmarketing x x x x x x x
Diabetes mellitus def Diabetes mellitus def postmarketing x x x x x x x
Oedema def Oedema def postmarketing x x x x x x x x x x
Fibrosis def Fibrosis def postmarketing x x x x
Hypersensitivity def Hypersensitivity def postmarketing x x x x x x x
Lung disorder def Lung disorder def postmarketing x x x x x x x x x
Pneumonia def Pneumonia def postmarketing x x x x x x
Pulmonary fibrosis def Pulmonary fibrosis def postmarketing x x x x
Urticaria def Urticaria def postmarketing x x x x x x x
Hepatic failure def Hepatic failure def postmarketing x x x x
Interstitial lung disease def Interstitial pneumonia postmarketing x x x x
Interstitial lung disease def postmarketing x x x x x x x x
Abdominal pain def Abdominal pain def x x x x x x x x x
Gastrointestinal pain def Abdominal pain def x x x x x x x x x
Abscess def Abscess def x x x x x x
Alopecia def Alopecia def x x x x x x x x x x
Anaemia def Anaemia def x x x x x x x x x x
Hypochromic anaemia def Hypochromic anaemia def x x
Angina pectoris def Angina pectoris def x x x x x x
Decreased appetite Anorexia def x x x x x x x x x x
Anxiety def Anxiety def x x x x x x
Arrhythmia def Arrhythmia def x x
Arthritis def Arthritis def x x x x x x
Asthenia def Asthenia def x x x x x x x x x
Fatigue def x
Asthma def Asthma def x x x x x x
Atrial fibrillation def Atrial fibrillation def x x
Back pain def Back pain def x x x x x x x x x
Balanitis def Balanitis def x x
Bone disorder def Bone disorder def x x
Breast disorder def Breast disorder def x x x
Bronchitis def Bronchitis def x x x x x x
Neck pain def Neck pain def x x x x x x
Chest pain def Chest pain def x x x x x x x x x
Confusional state def Confusional state def x x x x x x
Feeling abnormal Confusional state def x x x x x x
Conjunctivitis def Conjunctivitis def x x
Constipation def Constipation def x x x x x x x x x x
Cough def Cough def x x x x x x
Cough increased x x x x x
Cyst def Cyst def x x x x x x
Libido decreased def Libido decreased def x x x x x x x x x x
Disturbance in sexual arousal Libido decreased def x x x x x x x x x x
Dysphagia def Dysphagia def x x x x x x
Dehydration def Dehydration def x x x x x x
Diarrhoea def Diarrhoea def x x x x x x x x x x
Dizziness def Dizziness def x x x x x x x x x x
Syncope def x x x x x x
Dyspepsia def Dyspepsia def x x x x x x x x x x
Dyspnoea def Dyspnoea def x x x x x x x x x x
Dysuria def Dysuria def x x x x x x
Ecchymosis def Ecchymosis def x x
Effusion def Effusion def x x
Eosinophilia def Eosinophilia def x
Epistaxis def Epistaxis def x x x x x x
Dermatitis def Rash def x x x x x x x x x x
Rash def Rash def x x x x x x x x x x
Fatigue def Fatigue def x
Body temperature increased def Body temperature increased def x x x x x x
Flatulence def Flatulence def x x x x x x x x x x
Flushing def Flushing def x x x x x
Pathological fracture def Pathological fracture def x x x x
Gastritis def Gastritis def x x
Gastrointestinal disorder def Gastrointestinal disorder def x x x x x x x x x
Gout def Gout def x x x x x x
Gynaecomastia def Gynaecomastia def x x x x x x x x x x
Headache def Headache def x x x x x x x x x x
Cardiac arrest def Cardiac arrest def x x x x x x
Cardiac failure def Cardiac failure def x x x x x x x x x
Cardiac failure congestive def Cardiac failure congestive def x x x x x x
Haematuria def Haematuria def x x x x x x x x x x
Haemorrhage def Haemorrhage def x x x x x x
Haemoglobin def Haemorrhage def x x x x x x
Hernia def Hernia def x x x x x x
Herpes virus infection def Herpes NOS def x x x x x x
Herpes zoster def Herpes zoster def x x x x x x
Hirsutism def Hirsutism def x x x x x
Hydronephrosis def Hydronephrosis def x x x x x x
Hypercalcaemia def Hypercalcaemia def x x
Hypercholesterolaemia def Hypercholesterolaemia def x x x x x x
Hyperglycaemia def Hyperglycaemia def x x x x x x x x x x
Hypertension def Hypertension def x x x x x x x x x x
Hypertrophy def Hypertrophy def x x
Hypoglycaemia def Hypoglycaemia def x x
Ichthyosis def Ichthyosis def x
Ichthyosis acquired Ichthyosis def x
Immune system disorder def Immune system disorder def x x x x x
Incontinence def Incontinence def x x x x x x x x x x
Infarction def Infarction def x x x x x x
Infection def Infection def x x x x x x x x x x
Influenza def Influenza def x x x x x x x x x x
Intestinal obstruction def Intestinal obstruction def x x
Ischaemia def Ischaemia def x x
Jaundice def Jaundice def x x x x
Nephrolithiasis def Calculus of kidney def x x
Muscle spasms def Cramps of lower extremities x x x x x x
Cramp muscle def x x x x x x
Breast pain def Breast pain def x x x x x
Mediastinal disorder def Mediastinal disorder def x x x x
Melaena def Melaena def x x x x x x
Hypertonia def Hypertonia def x x x x x x
Muscle rigidity def Muscle rigidity def x x
Myocardial infarction def Myocardial infarction def x x x x x x
Acute coronary syndrome def Myocardial infarction def x x x x x x
Nausea def Nausea def x x x x x x x x x x
Neoplasm def Neoplasm def x x x x x x
Nervousness def Nervousness def x x x x x x
Tension def Nervousness def x x x x x x
Neutropenia def Neutropenia def x
Nocturia def Nocturia def x x x x x x x x x x
Obstruction def Obstruction def x x
Pain def Pain def x x x x x x x x x x
Paraesthesia def Paraesthesia def x x x x x x x x x
Pelvic pain def Pelvic pain def x x x x x x x x x
Tooth abscess Abscess periodontal def x x x x x x
Pharyngitis def Pharyngitis def x x x x x x
Pleural disorder def Pleural disorder def x x
Pleural effusion def Pleural effusion def x x
Pruritus def Pruritus def x x x x x x x x x x
Anorectal disorder def Rectal disorder def x x
Rhinitis def Rhinitis def x x x x x x
Sinusitis def Sinusitis def x x x x x x
Skin disorder def Skin disorder def x x x x x
Skin ulcer def Skin ulcer def x x
Cerebrovascular accident def Cerebrovascular accident def x x
Hyperhidrosis def Sweating def x x x x x x x x x x
Shock def Syncope def x x x x x x
Syncope def Syncope def x x x x x x
Loss of consciousness def Syncope def x x x x x x
Thrombocytopenia def Thrombocytopenia def x x
Thrombophlebitis def Thrombophlebitis def x x
Ulcer def Ulcer def x x
Deficiency anaemia Deficiency anaemia x x x x x x x x
Pollakiuria def Pollakiuria def x x x
Micturition urgency def x x x x x x
Urinary incontinence def Urinary incontinence def x x x x x x x
Urinary tract infection def Urinary tract infection def x x x x x x x
Urethral disorder def Urinary tract disorder def x x x x x x
Urinary tract disorder def Urinary tract disorder def x x x x x x
Visual impairment def Visual impairment def x x
Visual acuity reduced Visual impairment def x x
Blindness def Visual impairment def x x
Vomiting def Vomiting def x x x x x x x x x x
Weight increased def Weight increased def x x x x x x x x x
Weight decreased def Weight decreased def x x x x x x x x x
Dry mouth def Dry mouth def x x x x x x x x x x
Urinary retention def Urinary retention def x x x
Chills def Chills def x x x x x x x x x
Micturition urgency def Micturition urgency def x x x x x x
Oedema peripheral def Oedema peripheral def x x x x x x x x x x
Cataract def Cataract def x x x x x x
Cataract specified x x x x
Hepatic function abnormal Hepatic function abnormal x
Musculoskeletal stiffness Neck stiffness x x
Nuchal rigidity Neck stiffness x x
Blood urea increased Blood urea increased x x x x x x x
Gastrointestinal carcinoma Gastrointestinal carcinoma x x x x x
Blood creatinine increased Creatinine increased def x x x x x x x
Skin hypertrophy Skin hypertrophy x x
Injection site reaction def Injection site reaction def x
Liver function test abnormal Liver function test abnormal x
Bone pain def Bone pain def x x x x x x x x x
Blood alkaline phosphatase increased def Phosphatase alkaline increased x x
Aspartate aminotransferase increased def Aspartate aminotransferase increased def x x x x x x x x x
Dry skin def Dry skin def x x x x x x x x x x
Bladder stenosis Bladder stenosis x x
Deep vein thrombosis def Deep thrombophlebitis x x
Haemoglobin decreased def Haemoglobin decreased def x x x x x x x x
Iron deficiency anaemia def Iron deficiency anaemia def x x x x x x x x
Myalgia def Myalgia def x x x x x x
Musculoskeletal discomfort Myalgia def x x x x x x
Cardiac fibrillation Cardiac fibrillation x x
Tenderness def Tenderness def x x x x x x
Lung infiltration Lung infiltration x
Iron deficiency Iron deficiency x x x x x x x x
Erectile dysfunction def Erectile dysfunction def x x x x x x x x x x
Sepsis def Sepsis def x x x x x x
Breast tenderness Breast tenderness x x x x x
Rectal haemorrhage def Rectal haemorrhage def x x x x x x
Hepatobiliary disease def Hepatobiliary disease def x
Blood bilirubin increased def Blood bilirubin increased def x
Bradycardia def Bradycardia def x x
Laboratory test abnormal Laboratory test abnormal x x x x x
Neuropathy peripheral def Neuropathy def x x x x x x x
Osteoporotic fracture def Osteoporotic fracture def x
Face oedema def Face oedema def x x
Menopausal symptoms def Hot flush def x x x x x x x x x x
Hot flush def Hot flush def x x x x x x x x x x
Skin cancer def Skin carcinoma def x x x x x x
Aortic dissection def Dissecting aortic aneurysm, thoracic x x x x
Febrile neutropenia def Febrile neutropenia def x
Arterial disorder def Arterial disorder def x x x x x x
Cerebral ischaemia def Cerebral ischaemia def x x
Insomnia def Insomnia def x x x x x x x x x x
Muscular weakness def Myasthenia def x x x x x x
Death Death x
Dysphonia def Voice disturbance x x
Coronary artery disease def Coronary artery disease def x x x x x x
Somnolence def Somnolence def x x x x x x x x x x
Indication Labels
Carcinoma def x x x x
Metastatic carcinoma def x x x x
Neoplasm malignant def x x x x x
Prostate cancer def x x x x x
Prostate carcinoma def x x x x
Prostatic disorder def x x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L02BB03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. Bicalutamide : 55 side effects (BC Cancer)
  2. BICALUTAMIDE / SANDOZ BICALUTAMIDE : 65 side effects (Health Canada)
  3. BICALUTAMIDE / CO BICALUTAMIDE : 67 side effects (Health Canada)
  4. BICALUTAMIDE / NOVO-BICALUTAMIDE TABLETS : 67 side effects (Health Canada)
  5. BICALUTAMIDE : 109 side effects (FDA XML label)
  6. BICALUTAMIDE / CASODEX : 111 side effects (Drugs@FDA)
  7. BICALUTAMIDE / CASODEX : 115 side effects (Drugs@FDA)
  8. BICALUTAMIDE : 120 side effects (FDA XML label)
  9. BICALUTAMIDE / GEN-BICALUTAMIDE : 158 side effects (Health Canada)
  10. BICALUTAMIDE / CASODEX TAB 50MG : 161 side effects (Health Canada)