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Leuprorelin acetate

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ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5
Feeling hot Sensation of warmth 70.4% - 71.8% x
Weight increased Weight increased very common, 57.6% - 80.3% x x x
Hyperhidrosis Sweating 8.33% - 82.5% 5% - 7.7% x x x
Sweating increased 12.7% - 79.9% x x
Menopausal symptoms Hot flush 8.33% - 84.7% 5% - 7.7% x x x x x
Hot flush Hot flush 8.33% - 84.7% 5% - 7.7% x x x x x
Decreased appetite Decreased appetite 8.8% - 71.5% x
Appetite absent 1% - 22% x
Anorexia 2% - 3% x x x x
Weight decreased Weight decreased uncommon, 39.1% - 50.2% x x
Headache Headache dull 25.4% - 42.3% x
Headache 2% - 31.9% 6% - 9.2% x x x x x
Nasopharyngitis Common cold 26.8% - 28.2% x
Rhinitis Common cold 26.8% - 28.2% x
Rhinitis x x
Nervousness Nervousness 24.1% - 28.2% x x x x
Tension Nervousness 24.1% - 28.2% x x x x
Gynaecomastia Gynaecomastia 3% - 49% x x x x x
Breast tenderness Breast tenderness 3% - 49% x x x x x
Increased appetite Increased appetite 14.6% - 33.3% x x x x
Injection site induration Injection site induration 11.3% - 31% x
Pain Stinging 16% - 34.6% x
Pain 2.3% - 32.7% 0% x x x x x
Back pain Back pain 17.6% - 21.4% x x
Dermatitis Dermatitis 16.9% - 19.7% x x x x
Rash x x x x
Mood swings Mood swings 8% - 25.5% 2% - 3.1% x x x x
Affect lability Mood swings 8% - 25.5% 2% - 3.1% x x x x
Bone disorder Bone disorder very common x
Breast disorder Breast disorder very common x
Urethral disorder Urinary tract disorder very common x
Urinary tract disorder Urinary tract disorder very common x
Angiopathy Angiopathy very common x
Alopecia Alopecia 1.7% - 42% x x x x x
Oedema Oedema 8% - 23% x x x x
Diarrhoea Diarrhoea 4.4% - 23.7% x x x x
Injection site reaction Injection site reaction 8.16% - 37.5% x x x x
Oedema peripheral Oedema peripheral 12.5% x x
Depression Depression 8% - 14.3% 2% - 3.1% x
Injection site pain Injection site pain 11.3% - 12.7% x
Neck pain Neck pain 8.8% - 15% x x
Arthropathy Arthropathy 9% - 14.3% 0% x x x x
Osteoarthritis Arthropathy 9% - 14.3% 0% x x x x
Arthralgia Arthralgia 6.4% - 18.4% x x x x x
Musculoskeletal discomfort Arthralgia 6.4% - 18.4% x x x x x
Myalgia x x x x x
Vaginal inflammation Vaginal inflammation 5.1% - 14.3% 0% x
Vaginal infection Vaginal inflammation 5.1% - 14.3% 0% x
Leukopenia Leukopenia 1% - 18.3% x x
Insomnia Insomnia 6% - 21.8% 0% x x x x x
Somnolence Somnolence 8.51% x x
Body temperature increased Body temperature increased 5.63% - 11.3% x x x x
Asthenia Asthenia 3% - 64.1% 2% - 3% x x x x x
Fatigue x x x x
Nausea Nausea 3% - 92.2% 2% - 3% x x x x x
Dizziness Dizziness 0% - 18.3% 3% - 4.6% x x x x x
Syncope x x x x x
Lightheadedness x x x
Vertigo Vertigo 6.12% - 8.33% x x
Influenza Influenza 0% - 12.2% x x
Neuromyopathy Neuromyopathy 4.17% - 9.57% x x x x
Vomiting Vomiting 3% - 69.5% 2% - 3% x x x x x
Erectile dysfunction Erectile dysfunction 2% - 11% x x x x x
Constipation Constipation 1% - 11.5% x x x x x
Mental disorder Mental disorder common x
Mental state abnormal x
Gastrointestinal disorder Gastrointestinal disorder common x
Digestion impaired x x x x
Nervous system disorder Nervous system disorder common x
Malnutrition Malnutrition common x x
Dyspnoea Dyspnoea 3% - 5.4% x x x x
Dehydration Dehydration 0% - 8.16% x x x x
Phlebitis Phlebitis 1% - 7% x x x x
Thrombophlebitis Thrombophlebitis 1% - 7% x x x
Erythema Erythema 0.9% - 11.2% x x x x
Contusion Contusion 1.7% - 2.5% x
Cardiac failure congestive Cardiac failure congestive 1% - 3% x x x x
Bone pain Bone pain 1% - 3% x x x x x
Anxiety Anxiety 0% - 3% x x x x
Paraesthesia Paraesthesia 0% - 3% x x x x x
Paresthesia lower limb x
Muscle spasms Muscle spasms 0% - 3% x x x x
Cramps of lower extremities x
Pruritus Pruritus 0.4% - 1.4% x x x x x
Immune system disorder Immune system disorder uncommon x
Skin disorder Unspecified disorder of skin and subcutaneous tissue uncommon x
Induration Induration 0.4% x x x x x
Ulcer Ulcer 0.1% x
Abscess Abscess x x x x
Amblyopia Amblyopia x x x x
Amnesia Amnesia x
Anaphylactic shock Anaphylactic shock x x x x
Anaemia Anaemia x x x x
Angina pectoris Angina pectoris x x x x
Arrhythmia Arrhythmia x x x x
Asthma Asthma x x
Ataxia Ataxia x
Atrial fibrillation Atrial fibrillation x
Bronchitis Bronchitis x
Transient ischaemic attack Transient ischaemic attack x x x x
Cervix disorder Cervix disorder x
Colitis Colitis x
Infection Infection x x x x
Confusional state Confusional state x
Feeling abnormal Confusional state x
Malaise x
Cough Cough x x x x
Cough increased x
Libido decreased Libido decreased x x x
Disturbance in sexual arousal Libido decreased x x x
Libido increased x x x
Dysphagia Dysphagia x x x x
Delusion Delusion x x x x
Diabetes mellitus Diabetes mellitus x x x x x
Diabetic x
Duodenal ulcer Duodenal ulcer x x x x
Dysmenorrhoea Dysmenorrhoea x
Dyspepsia Dyspepsia x x x
Digestion impaired x x x x
Dysuria Dysuria x x
Ecchymosis Ecchymosis x x x x
Eosinophilia Eosinophilia x x
Epididymitis Epididymitis x
Epistaxis Epistaxis x x x x
Eructation Eructation x
Erythema multiforme Erythema multiforme x
Rash Rash x x x x
Fatigue Fatigue x x x x
Feminisation acquired Feminization x
Flatulence Flatulence x x
Multiple fractures Fracture x
Fracture Fracture x
Gastroenteritis Gastroenteritis x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x x x
Gingival bleeding Gingival bleeding x
Gingivitis Gingivitis x x
Goitre Goitre x x x x
Hair disorder Hair disorder x
Cardiac failure Cardiac failure x
Haematoma Haematoma x x x x
Haemoptysis Haemoptysis x x x x
Hepatomegaly Hepatomegaly x
Hernia Hernia x
Hiccups Hiccups x
Hirsutism Hirsutism x
Hypercholesterolaemia Hypercholesterolaemia x
Hyperglycaemia Hyperglycaemia x x x
Hyperlipidaemia Hyperlipidaemia x x x x
Hypersensitivity Hypersensitivity x x
Hypertension Hypertension x x x x x
Hypertrophy Hypertrophy x
Hypoaesthesia Hypoaesthesia x x x x
Numbness x x x x
Hypoglycaemia Hypoglycaemia x x x x
Hypogonadism Hypogonadism x
Hypokalaemia Hypokalaemia x
Hypoproteinaemia Hypoproteinaemia x x x x
Hypotension Hypotension x x x x x
Orthostatic hypotension Orthostatic hypotension x
Body temperature decreased Body temperature decreased x
Hypothermia Body temperature decreased x
Incontinence Incontinence x x x x x
Libido increased Libido increased x x x
Inflammation Inflammation x x x x
Intestinal obstruction Intestinal obstruction x
Ischaemia Ischaemia x x x x
Jaundice Jaundice x x x x
Lethargy Lethargy x x x x x
Leukocytosis Leukocytosis x
Lymphoedema Lymphoedema x x x x
Breast pain Breast pain x x x x
Menstrual disorder Menstrual disorder x x
Hypertonia Hypertonia x x
Muscle atrophy Muscle atrophy x
Myopathy Myopathy x
Myocardial infarction Myocardial infarction x x x x x
Acute coronary syndrome Myocardial infarction x x x x x
Nail disorder Nail disorder x
Neoplasm Neoplasm x
Night sweats Night sweats x
Nodule Nodule x x x x
Sensory loss Numbness x x x x
Nocturia Nocturia x x x
IIIrd nerve paralysis Ophthalmoplegia x
Ophthalmoplegia Ophthalmoplegia x
Osteoporosis Osteoporosis x
Pain in extremity Pain in extremity x
Palpitations Palpitations x
Penis disorder Penis disorder x x x x x
Peptic ulcer Peptic ulcer x x x x
Tooth abscess Abscess periodontal x
Neuropathy peripheral Neuropathy peripheral x x x x
Neuropathy x
Personality disorder Personality disorder x
Pharyngitis Pharyngitis x x x x
Pituitary haemorrhage Pituitary apoplexy x x x x x
Pleural effusion Pleural effusion x x x x
Pleural rub Pleural rub x x x x
Pneumonia Pneumonia x x x x
Prostatic disorder Prostatic disorder x
Precocious puberty Precocious puberty x
Pulmonary embolism Pulmonary embolism x
Pulmonary fibrosis Pulmonary fibrosis x x x x
Purpura Purpura x
Vascular purpura Purpura x
Anorectal disorder Rectal disorder x
Rectal polyp Rectal polyp x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Convulsion Convulsion x x x x
Shock Shock x
Syncope x x x x x
Sinusitis Sinusitis x
Sleep disorder Sleep disturbance x
Sleep disorder x x x x
Spinal cord compression Spinal cord compression x x
Spinal osteoarthritis Spondylosis x x x x
Cerebrovascular accident Cerebrovascular accident x x x x x
Swelling Swelling x x x x
Syncope Syncope x x x x x
Loss of consciousness Syncope x x x x x
Blacked-out (not amnesia) x x x x
Tachycardia Tachycardia x x x
Tenosynovitis Tenosynovitis x x x x
Testicular pain Testicular pain x x x x x
Thirst Thirst x x x x
Thrombocytopenia Thrombocytopenia x
Thrombosis Thrombosis x x x x
Tinnitus Tinnitus x x x x
Tremor Tremor x
Ureteric obstruction Ureteric obstruction x x
Pollakiuria Pollakiuria x x x x x
Micturition urgency x x x x x
Urinary incontinence Urinary incontinence x x
Urinary tract infection Urinary tract infection x x x x
Urticaria Urticaria x x x x
Varicose vein Varicose vein x x x x
Virilism Virilism x
Dry mouth Dry mouth x x x x
Spinal fracture Spinal fracture x x x x
Urinary retention Urinary retention x
Peripheral vascular disorder Peripheral vascular disorder x
Sudden cardiac death Sudden cardiac death x x x x x
Chills Chills x x x x
Rigors x
Skin odour abnormal Body odor x
Micturition urgency Micturition urgency x x x x x
Hyperphosphataemia Hyperphosphataemia x x x x
Hepatic function abnormal Hepatic function abnormal x x x x
Deep vein thrombosis Deep vein thrombosis x
Migraine Migraine x
Antinuclear antibody positive Antinuclear antibody positive x
Blood urea increased Blood urea increased x x x x
Urea increased x
Blood creatinine increased Creatinine increased x x x x
Swelling face Swelling face x x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Red blood cell sedimentation rate increased Red blood cell sedimentation rate increased x
Growth retardation Growth retardation x
High density lipoprotein decreased High density lipoprotein decreased x
Impaired healing Impaired healing x
Skin hypertrophy Skin hypertrophy x
Injury Accidental injury x
Liver function test abnormal Liver function test abnormal x x x x
Raised liver function tests x
Muscular weakness Muscular weakness x
Myasthenia x
Prothrombin level increased Prothrombin level increased x x x x
Skin discolouration Skin discolouration x
Dry skin Dry skin x x x x
Sinus congestion Sinus congestion x x x x
Testicular atrophy Testicular atrophy x x x x x
Liver injury Liver injury x x x x
Traumatic liver injury Liver injury x x x x
Haemoglobin decreased Haemoglobin decreased x
Photosensitivity reaction Photosensitivity reaction x x x x
Leukoderma Leukoderma x
Interstitial lung disease Interstitial lung disease x x x x
Malaise Malaise x
Discomfort Malaise x
Ill-defined disorder Malaise x
Myalgia Myalgia x x x x x
Thinking abnormal Thinking abnormal x
Mental disability Thinking abnormal x
Tenderness Tenderness x
Vaginal odour Vaginal odour x
Lung infiltration Lung infiltration x x x x
Activated partial thromboplastin time prolonged Activated partial thromboplastin time prolonged x x x x
Prostatic pain Prostatic pain x x x x
Blood testosterone decreased Testosterone low x x
Hearing impaired Auditory disorder NOS x x x x
Hyperuricosuria Uricaciduria x
Blood bilirubin increased Blood bilirubin increased x x x x
Dry eye Dry eye x x x x
Atrophy Atrophy x
Pelvic fibrosis Pelvic fibrosis x x x x
Pituitary infarction Pituitary infarction x
Vision blurred Vision blurred x x x x
Abdominal distension Enlargement abdomen x x x x
Cold sweat Sticky skin x
Sticky skin Sticky skin x
Platelet count decreased Platelet count decreased x x x x
Suicidal ideation Suicidal ideation x x x x
Agitation Hyperkinesia x x
Hyperkinesia Hyperkinesia x x
Bladder pain Bladder spasm x
Bladder spasm Bladder spasm x
Red blood cell count decreased Red blood cell count decreased x
Bradycardia Bradycardia x x x x
Lymphadenopathy Lymphadenopathy x x
Dementia Dementia x
Paralysis Paralysis x x x x
Hypercalcaemia Ca++ increased x x x x
Metastases to spine Metastases to spine x x x
Bladder cancer Bladder carcinoma x
Skin cancer Skin carcinoma x x x x
Acne Acne x
Haematocrit decreased Haematocrit decreased x x
White blood cell count decreased White blood cell count decreased x x x x
White blood cell count increased White blood cell count increased x x x
Blood testosterone increased Serum testosterone increased x
Dysgeusia Taste sour x x
Blood glucose increased Glucose increased x
Blood potassium decreased Potassium low x x x x
Bone density decreased Bone density decreased x x
Penile swelling Penile swelling x x x x
Blood uric acid increased Uric acid increased x x x x
Vaginal haemorrhage Vaginal haemorrhage x x
Loss of libido Loss of libido x x x
Embolism arterial Arterial thromboembolism x
Visual impairment Abnormal vision x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CAS Number / LUCRIN (LEUPRORELIN ACETATE)

Side effects:147
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label