Bisoprolol
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
Headache
|
Headache
|
postmarketing — 8.3% - 10.9%
|
11.4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
Fatigue
|
postmarketing — 6.6% - 8.2%
|
1.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
postmarketing — 0.4% - 1.5%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Fatigue
|
Fatigue
|
postmarketing — 6.6% - 8.2%
|
1.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Infection
|
Infection
|
5% - 6.9%
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Rhinitis
|
Rhinitis
|
2.9% - 8.3%
|
3%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
Dizziness
|
postmarketing — 2.9% - 4.9%
|
3.8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Oedema
|
Oedema
|
3% - 3.7%
|
3.8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Oedema peripheral
|
Oedema peripheral
|
3% - 3.5%
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Bronchitis
|
Bronchitis
|
2.8%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Diarrhoea
|
Diarrhoea
|
postmarketing — 2.6% - 3.5%
|
1.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Arthralgia
|
Arthralgia
|
2.2% - 4.2%
|
2.3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal discomfort
|
Arthralgia
|
2.2% - 4.2%
|
2.3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
2.1%
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Cough
|
Cough
|
2.5% - 4.2%
|
4.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Insomnia
|
Insomnia
|
1.5% - 2.5%
|
2.3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Nausea
|
Nausea
|
postmarketing — 1.5% - 2.2%
|
1.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pharyngitis
|
Pharyngitis
|
2.2% - 4.2%
|
2.3%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Sinusitis
|
Sinusitis
|
2.2% - 4.9%
|
1.5%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Abdominal pain
|
Abdominal pain
|
2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal pain
|
Abdominal pain
|
2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Back pain
|
Back pain
|
2.1%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Ear pain
|
Ear pain
|
2.1%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Body temperature increased
|
Body temperature increased
|
2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Muscle spasms
|
Cramp muscle
|
postmarketing — 2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pain
|
Pain
|
2.1%
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Ache
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Myalgia
|
Myalgia
|
2.1%
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Erectile dysfunction
|
Erectile dysfunction
|
2.1%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Loss of libido
|
Loss of libido
|
2.1%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Injury
|
Injury
|
2.1%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Chest pain
|
Chest pain
|
1.1% - 2.1%
|
0.8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea
|
Dyspnoea
|
1.1% - 1.5%
|
0.8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypoaesthesia
|
Hypoaesthesia
|
1.1% - 1.5%
|
0.8%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Numbness of limbs
|
postmarketing, common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Vomiting
|
Vomiting
|
postmarketing — 1.1% - 1.5%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dry mouth
|
Dry mouth
|
0.7% - 1.3%
|
1.5%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hyperhidrosis
|
Sweating increased
|
0.7% - 1%
|
1.5%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Sweating
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Sleep disorder
|
Sleep disorder
|
uncommon
|
|
|
x
|
|
|
|
|
|
|
|
|
Sleep disturbance
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Bradycardia
|
Bradycardia
|
postmarketing — 0.4% - 0.5%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Depression
|
Depression
|
0% - 0.2%
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Alopecia
|
Alopecia
|
very rare, postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthma
|
Asthma
|
postmarketing, uncommon
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Breast disorder
|
Breast disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Conjunctivitis
|
Conjunctivitis
|
very rare, postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Connective tissue disorder
|
Connective tissue disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Constipation
|
Constipation
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Dermatitis
|
Rash
|
very rare — rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Rash
|
Rash
|
very rare — rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eye disorder
|
Eye disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Congenital eye disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Flushing
|
Flushing
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Hallucination
|
Hallucination
|
rare
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Cardiac failure
|
Cardiac failure
|
postmarketing, common
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Hepatitis
|
Hepatitis
|
postmarketing, rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Hypersensitivity
|
Hypersensitivity
|
postmarketing, rare
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Hypotension
|
Hypotension
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Orthostatic hypotension
|
Orthostatic hypotension
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Mediastinal disorder
|
Mediastinal disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Nervous system disorder
|
Nervous system disorder
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Nightmare
|
Nightmare
|
rare
|
|
|
x
|
|
|
|
|
|
|
x
|
x
|
Pruritus
|
Pruritus
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Psoriasis
|
Psoriasis
|
very rare, postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Shock
|
Syncope
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Shock
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Syncope
|
Syncope
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Loss of consciousness
|
Syncope
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Angiopathy
|
Angiopathy
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Muscular weakness
|
Muscular weakness
|
postmarketing, uncommon
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Hearing impaired
|
Auditory disorder NOS
|
postmarketing, rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Partial hearing loss
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hepatobiliary disease
|
Hepatobiliary disease
|
postmarketing
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Feeling cold
|
Coldness
|
postmarketing, common
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Rhinitis allergic
|
Rhinitis allergic
|
postmarketing, rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Congenital anomaly
|
Congenital anomaly
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
x
|
Developmental delay
|
Congenital anomaly
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
x
|
Agranulocytosis
|
Agranulocytosis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Angioedema
|
Angioedema
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Anosmia
|
Anosmia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Anxiety
|
Anxiety
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Aphasia
|
Aphasia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Arrhythmia
|
Arrhythmia
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Atrial fibrillation
|
Atrial fibrillation
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Atrioventricular block
|
Atrioventricular block
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Mental disorder
|
Mental disorder
|
|
|
|
x
|
|
|
|
|
|
|
|
|
Bronchospasm
|
Bronchospasm
|
postmarketing — 0%
|
0%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Catatonia
|
Catatonia
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Cerebrovascular disorder
|
Cerebrovascular disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Neck pain
|
Neck pain
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Coma
|
Coma
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Confusional state
|
Confusional state
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Feeling abnormal
|
Confusional state
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Malaise
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cystitis
|
Cystitis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Bladder pain
|
Cystitis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cystitis noninfective
|
Cystitis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Libido decreased
|
Libido decreased
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Disturbance in sexual arousal
|
Libido decreased
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis exfoliative
|
Dermatitis exfoliative
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Scleroderma
|
Scleroderma
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Somnolence
|
Drowsiness
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Somnolence
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dysgeusia
|
Dysgeusia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyspepsia
|
Dyspepsia
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eczema
|
Eczema
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Embolism
|
Embolism
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Congenital eye disorder
|
Congenital eye disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Multiple fractures
|
Fracture
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Fracture
|
Fracture
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Gastritis
|
Gastritis
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Gout
|
Gout
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cardiac arrest
|
Cardiac arrest
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Cardiac failure congestive
|
Cardiac failure congestive
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hepatomegaly
|
Hepatomegaly
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Hyperaesthesia
|
Hyperaesthesia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hypoglycaemia
|
Hypoglycaemia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Ischaemia
|
Ischaemia
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Arthropathy
|
Arthropathy
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Osteoarthritis
|
Arthropathy
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Laryngospasm
|
Laryngospasm
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Left ventricular failure
|
Left ventricular failure
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Pulmonary oedema
|
Left ventricular failure
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Pulmonary oedema
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Breast pain
|
Breast pain
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Myocardial infarction
|
Myocardial infarction
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Acute coronary syndrome
|
Myocardial infarction
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Neuralgia
|
Neuralgia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Palpitations
|
Palpitations
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Paresis
|
Paresis
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Paraesthesia
|
Paraesthesia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Tingling sensation
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Peyronie's disease
|
Peyronie's disease
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Peptic ulcer
|
Peptic ulcer
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Pneumonia
|
Pneumonia
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Polyuria
|
Polyuria
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Urine output increased
|
Polyuria
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Purpura
|
Purpura
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Vascular purpura
|
Purpura
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Respiratory failure
|
Respiratory insufficiency
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Speech disorder
|
Speech disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Stridor
|
Stridor
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Tachycardia
|
Tachycardia
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
x
|
Thrombocytopenia
|
Thrombocytopenia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Tinnitus
|
Tinnitus
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Tremor
|
Tremor
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Erythema
|
Erythema
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Urinary tract infection
|
Urinary tract infection
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Urticaria
|
Urticaria
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Vasculitis
|
Vasculitis
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Ventricular fibrillation
|
Ventricular fibrillation
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Vertigo
|
Vertigo
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Viral infection
|
Viral infection
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Weight increased
|
Weight increased
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Encephalopathy
|
Encephalopathy
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Agitation
|
Agitation
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Mood swings
|
Mood swings
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Affect lability
|
Mood swings
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Generalised oedema
|
Generalised oedema
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Fluid retention
|
Generalised oedema
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Toxic epidermal necrolysis
|
Necrolysis epidermal
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Eye pain
|
Eye pain
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Skin discolouration
|
Skin discolouration
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Arterial thrombosis
|
Arterial thrombosis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Skin irritation
|
Skin irritation
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Renal colic
|
Renal colic
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Colitis ischaemic
|
Colitis ischaemic
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Skin hyperpigmentation
|
Skin hyperpigmentation
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Malaise
|
Malaise
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Discomfort
|
Malaise
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Ill-defined disorder
|
Malaise
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Muscle twitching
|
Muscle twitching
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea exertional
|
Dyspnoea exertional
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Disorientation
|
Disorientation
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Abdominal pain upper
|
Epigastric pain not food-related
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Peripheral ischaemia
|
Peripheral ischaemia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Raynaud's phenomenon
|
Raynaud-like disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Vein disorder
|
Vein disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Respiratory tract haemorrhage
|
Respiratory tract haemorrhage
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Galactorrhoea
|
Galactorrhoea
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Toxicity to various agents
|
Overdose effect
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Lacrimal disorder
|
Lacrimation abnormal NOS
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Oropharyngeal discomfort
|
Throat sore
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Oropharyngeal pain
|
Throat sore
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cutaneous vasculitis
|
Cutaneous vasculitis
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Conduction disorder
|
Conduction disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Purine metabolism disorder
|
Purine metabolism disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Peripheral coldness
|
Peripheral coldness
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Extrasystoles
|
Extrasystoles
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Abnormal dreams
|
Vivid dreams
|
0%
|
0%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Photosensitivity reaction
|
Photosensitivity
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Balance disorder
|
Unsteadiness
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Respiratory distress
|
Respiratory distress
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Visual impairment
|
Visual disturbance
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Abnormal vision
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Stillbirth
|
Stillbirth
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Menopausal symptoms
|
Hot flush
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Hot flush
|
Hot flush
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Blood triglycerides increased
|
Serum triglycerides increased
|
|
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Thrombocytopenic purpura
|
Thrombocytopenic purpura
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Cardiomyopathy
|
Cardiomyopathy
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Intermittent claudication
|
Claudication
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Ageusia
|
Ageusia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Respiratory tract oedema
|
Respiratory tract oedema
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 80 |
Source: | medicines.org.au |
---|
Side effects: | 84 |
Source: | medicines.org.au |
---|
Side effects: | 89 |
Source: | FDA Structured Product Label |
---|
Side effects: | 92 |
Source: | FDA Structured Product Label |
---|
Side effects: | 93 |
Source: | FDA Structured Product Label |
---|
Side effects: | 93 |
Source: | FDA Structured Product Label |
---|
Side effects: | 94 |
Source: | FDA Structured Product Label |
---|
Side effects: | 94 |
Source: | FDA Structured Product Label |
---|
Side effects: | 109 |
Source: | Health Canada |
---|
Side effects: | 110 |
Source: | Health Canada |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|