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Metolazone

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: C03BA08

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5
Dizziness Dizziness 10.2% x x x x x
Lightheadedness 10.2% x x x x x
Syncope x x x x x
Headache Headache 9.3% x x x x x
Muscle spasms Cramp muscle 5.8% x x x x x
Muscle spasms x x x x
Asthenia Fatigue 4.4% x x x x x
Asthenia x x x x x
Fatigue Fatigue 4.4% x x x x x
Lassitude 4.4% x
Lethargy Lethargy 4.4% x
Malaise Malaise 4.4% x
Discomfort Malaise 4.4% x
Discomfort 2.7% x x x x
Feeling abnormal Malaise 4.4% x
Ill-defined disorder Malaise 4.4% x
Arthralgia Arthralgia 3.1% x x x x x
Musculoskeletal discomfort Arthralgia 3.1% x x x x x
Swelling Swelling 3.1% x
Chest pain Chest pain 2.7% x x x x x
Abdominal pain Abdominal pain x x x x
Gastrointestinal pain Abdominal pain x x x x
Agranulocytosis Agranulocytosis x x x x x
Anaemia Anaemia x x
Decreased appetite Anorexia x x x x x
Anxiety Anxiety x
Back pain Back pain x
Constipation Constipation x x x x x
Cough Cough x
Dermatitis Dermatitis x x x x x
Rash x x x x x
Diarrhoea Diarrhoea x x x x x
Somnolence Drowsiness x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x x x
Epistaxis Epistaxis x
Rash Rash x x x x x
Glycosuria Glycosuria x x x x x
Hepatitis Hepatitis x x x x x
Hypercalcaemia Hypercalcaemia x x x x
Hyperglycaemia Hyperglycaemia x x x x x
Hypersensitivity Hypersensitivity x x x x x
Hypokalaemia Hypokalaemia x x x x x
Hyponatraemia Hyponatraemia x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x
Eye pruritus Eye pruritus x
Jaundice cholestatic Jaundice cholestatic x x x x x
Leukopenia Leukopenia x x x x x
Nausea Nausea x x x x x
Nervousness Nervousness x
Tension Nervousness x
Nocturia Nocturia x
Pain Pain x
Palpitations Palpitations x x x x x
Pancreatitis Pancreatitis x x x x x
Paraesthesia Paraesthesia x x x x x
Petechiae Petechiae x x x x
Pruritus Pruritus x x x x
Purpura Purpura x x x x x
Vascular purpura Purpura x x x x x
Erythema multiforme Stevens-Johnson syndrome x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x x
Shock Syncope x x x x x
Syncope Syncope x x x x x
Loss of consciousness Syncope x x x x x
Thrombocytopenia Thrombocytopenia x x x x
Tinnitus Tinnitus x
Urticaria Urticaria x x x x x
Venous thrombosis Venous thrombosis x x x x x
Vertigo Vertigo x x x x
Vomiting Vomiting x x x x x
Dry mouth Dry mouth x x x x
Chills Chills x x x x x
Agitation Agitation x x x x x
Hypochloraemia Hypochloraemia x x x x x
Hypophosphataemia Hypophosphataemia x x x x x
Alkalosis hypochloraemic Alkalosis hypochloraemic x x x x x
Hypomagnesaemia Hypomagnesaemia x x x x
Skin necrosis Skin necrosis x x x x
Skin exfoliation Skin necrosis x x x x
Dry skin Dry skin x
Sinus congestion Sinus congestion x
Hypoplastic anaemia Hypoplastic anaemia x x x
Dyspepsia Epigastric distress x x x x
Abdominal discomfort Abdominal discomfort x
Dysgeusia Taste bitter x
Erectile dysfunction Erectile dysfunction x x x x x
Oropharyngeal discomfort Throat sore x
Oropharyngeal pain Throat sore x
Cutaneous vasculitis Cutaneous vasculitis x x x x x
Major depression Psychotic depression x x x x
Peripheral coldness Peripheral coldness x
Vision blurred Vision blurred x x x x x
Photosensitivity reaction Photosensitivity x x x x x
Neuropathy peripheral Neuropathy x x x x x
Hypovolaemia Hypovolaemia x x x x x
Vasculitis necrotising Angiitis necrotising x x x x x
Blood uric acid increased Hyperuricaemia x x x x x
Hyperuricaemia Hyperuricaemia x x x x x
Hypertension Hypertensive x
Blood urea increased Serum urea increased x x x x x
Insomnia Insomnia x x x x x
Abdominal distension Abdominal bloating x x x x x
Flatulence Abdominal bloating x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

METOLAZONE / ZAROXOLYN

Side effects:55
Source:Health Canada

METOLAZONE

Side effects:64
Source:FDA Structured Product Label

METOLAZONE

Side effects:65
Source:FDA Structured Product Label

metolazone

Side effects:65
Source:FDA Structured Product Label

metolazone

Side effects:81
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label