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Allopurinol

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: M04AA01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12
Rash maculo-papular Rash maculo-papular 10% x x x x x x x
Dermatitis Rash 1.5% x x x x x x x x x x x x
Rash Rash 1.5% x x x x x x x x x x x x
Nausea Nausea 1.3% x x x x x x x x x x x x
Vomiting Vomiting 1.2% x x x x x x x x x x x x
Agranulocytosis Agranulocytosis postmarketing x x x x x x x x x x x
Albuminuria Albuminuria postmarketing x x x x x x
Amblyopia Amblyopia postmarketing x x x x x x
Amnesia Amnesia postmarketing x x x x x x
Anaemia Anaemia postmarketing x x x x x x x x
Aplastic anaemia Aplastic anaemia postmarketing x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia postmarketing x x x x x x
Decreased appetite Anorexia postmarketing x x x x x x
Asthenia Asthenia postmarketing x x x x x x x x x x x
Asthma Asthma postmarketing x x x x x
Bronchospasm Bronchospasm postmarketing x x x x x
Confusional state Confusional state postmarketing x x x x x x x x
Feeling abnormal Confusional state postmarketing x x x x x x x x
Malaise postmarketing x x x x x x x x x
Conjunctivitis Conjunctivitis postmarketing x x x x x x
Dizziness Dizziness postmarketing x x x x x x
Furuncle Furunculosis postmarketing x x x x x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage postmarketing x x x x x x x
Gynaecomastia Gynaecomastia postmarketing x x x x x x x x x x
Haematuria Haematuria postmarketing x x x x x x x x x x
Hypercalcaemia Hypercalcaemia postmarketing x x x x x x x
Hyperlipidaemia Hyperlipidaemia postmarketing x x x x x x x x x x
Infertility Infertility postmarketing x x x x x x x x x
Iritis Iritis postmarketing x x x x x x
Lymphocytosis Lymphocytosis postmarketing x x x x x x
Nephritis Nephritis postmarketing x x x x x x x x
Optic neuritis Optic neuritis postmarketing x x x x x x
Pancytopenia Pancytopenia postmarketing x x x x x x x
Bone marrow depression x x x
Pericarditis Pericarditis postmarketing x x x x x x
Pharyngitis Pharyngitis postmarketing x x x x x x
Retinitis Retinitis postmarketing x x x x x x
Rhinitis Rhinitis postmarketing x x x x x
Stomatitis Stomatitis postmarketing x x x x x x x x x
Hyperhidrosis Sweating postmarketing x x x x x x
Sweating increased x
Thrombophlebitis Thrombophlebitis postmarketing x x x x x x x
Tinnitus Tinnitus postmarketing x x x x x
Vasodilation procedure Vasodilation postmarketing x x x x x x
Vertigo Vertigo postmarketing x x x x x x x x x x
Peripheral vascular disorder Peripheral vascular disorder postmarketing x x x x x x
Peroneal nerve palsy Footdrop postmarketing x x x x x x
Cataract Cataract postmarketing x x x x x x x x x x
Tongue disorder Tongue oedema postmarketing x x x x x x
Tongue oedema Tongue oedema postmarketing x x x x x x
Reticulocytosis Reticulocytosis postmarketing x x x x x x
Malaise Malaise postmarketing x x x x x x x x x
Discomfort Malaise postmarketing x x x x x x x x x
Ill-defined disorder Malaise postmarketing x x x x x x x x x
Myalgia Myalgia postmarketing x x x x x x x
Musculoskeletal discomfort Myalgia postmarketing x x x x x x x
Arthralgia x x x x x x x x x x x
Salivary gland enlargement Salivary gland swelling postmarketing x x x x x x
Erectile dysfunction Erectile dysfunction postmarketing x x x x x x x x x x
Pancreatitis haemorrhagic Pancreatitis haemorrhagic postmarketing x x x x x x
Bradycardia Bradycardia postmarketing x x x x x x x x x x x
Lymphadenopathy Lymphadenopathy postmarketing x x x x x x x x x
Generalized lymphadenopathy x x x
Skin oedema Skin oedema postmarketing x x x x x x
Face oedema Face oedema postmarketing x x x x x x
Insomnia Insomnia postmarketing x x x x x x
Loss of libido Loss of libido postmarketing x x x x x x
Abdominal pain Abdominal pain x x x x x x x x
Stomach ache x
Gastrointestinal pain Abdominal pain x x x x x x x x
Lactic acidosis Lactic acidosis x
Alopecia Alopecia x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock x x
Angina pectoris Angina pectoris x x x x
Angioedema Angioedema x x x x
Apnoea Apnoea x
Arthralgia Arthralgia x x x x x x x x x x x
Ataxia Ataxia x x x x
Mental disorder Mental disorder x
Blast cell crisis Blast cell crisis x
Breast disorder Breast disorder x
Cardiovascular disorder Cardiovascular disorder x
Cellulitis Cellulitis x
Cerebral infarction Cerebral infarction x
Coma Coma x x x x x
Infection Infection x
Constipation Constipation x
Contusion Contusion x
Depression Depression x
Dermatitis exfoliative Dermatitis exfoliative x x x x x x x
Dermatitis atopic Dermatitis atopic x
Diabetes mellitus Diabetes mellitus x x x x
Diarrhoea Diarrhoea x x x x x x x x x x
Disseminated intravascular coagulation Disseminated intravascular coagulation x
Somnolence Drowsiness x x x
Somnolence x x x x x x x x x
Dysgeusia Dysgeusia x x x x
Dyspepsia Dyspepsia x x x x x x x x x
Digestion impaired x x x
Dysuria Dysuria x
Ecchymosis Ecchymosis x x x x x x x
Eczema Eczema x x x x x x
Oedema Oedema x x x x x
Eosinophilia Eosinophilia x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x x x x x x x x x
Epilepsy Epilepsy x x x
Epistaxis Epistaxis x x x x x x x
Erythema multiforme Erythema multiforme x
Stevens-Johnson syndrome x x x x x x x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x x x x x x x x x x x x
Flatulence Flatulence x
Flushing Flushing x
Gastritis Gastritis x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x
Digestion impaired x x x
Glycosuria Glycosuria x
Headache Headache x x x x x x x x x x x x
Cardiac disorder Cardiac disorder x
Cardiac failure Cardiac failure x
Haematemesis Haematemesis x x x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Hepatitis Hepatitis x x x x x
Hepatomegaly Hepatomegaly x x x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia x x x x x x x
Hyperglycaemia Hyperglycaemia x
Hyperkalaemia Hyperkalaemia x
Hypernatraemia Hypernatraemia x
Hypersensitivity Hypersensitivity x x x x x x
Hypertension Hypertension x x x x
Hypocalcaemia Hypocalcaemia x
Hypokalaemia Hypokalaemia x
Hyponatraemia Hyponatraemia x
Hypotension Hypotension x
Angioimmunoblastic T-cell lymphoma Angioimmunoblastic T-cell lymphoma x x x x
Immune system disorder Immune system disorder x
Infertility male Infertility male x
Intestinal obstruction Intestinal obstruction x
Jaundice Jaundice x x
Jaundice cholestatic Jaundice cholestatic x x x x x x x
Renal failure acute Renal failure acute x
Leukocytosis Leukocytosis x x x x x x x x x x
Leukopenia Leukopenia x x x x x x x x x x x
Lichen planus Lichen planus x x x x x x
Liver disorder Liver disorder x x x
Hepatocellular injury Liver disorder x x x
Hepatocellular injury x
Foetor hepaticus Liver disorder x x x
Hypotonia Hypotonia x
Muscle relaxant therapy Hypotonia x
Myopathy Myopathy x x x x x x
Myoclonus Myoclonus x
Tubulointerstitial nephritis Nephritis interstitial x x
Nervous system disorder Nervous system disorder x
Neuritis Neuritis x x x x x x x x x
Neuropathy peripheral Neuritis x x x x x x x x x
Neuropathy peripheral x x x x x x
Neuropathy x x x
Neutropenia Neutropenia x
Hypoaesthesia Numbness x
Sensory loss Numbness x
Oliguria Oliguria x
Pain Pain x x
Paraesthesia Paraesthesia x x x x x x x x
Tingling sensation x
Proctitis Proctitis x
Pruritus Pruritus x x x x x x x x x x
Pulmonary embolism Pulmonary embolism x
Purpura Purpura x x x x x x
Vascular purpura Purpura x x x x x x
Convulsion Convulsion x x
Convulsions generalised x
Septic shock Septic shock x
Splenomegaly Splenomegaly x
Status epilepticus Status epilepticus x
Steatorrhoea Steatorrhoea x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x x x x x
Cerebrovascular accident Cerebrovascular accident x
Swelling Swelling x
Thrombocytopenia Thrombocytopenia x x x x x x x x x x x x
Tremor Tremor x
Tumour lysis syndrome Tumour lysis syndrome x
Ulcer Ulcer x
Azotaemia Uremia x x x x x x x x x
Urinary tract infection Urinary tract infection x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x x x x x x x x
Vasculitis Vasculitis x x x x x x x x x
Ventricular fibrillation Ventricular fibrillation x
Visual impairment Disorder sight x x x
Water intoxication Water intoxication x
Weight increased Weight increased x
Wheezing Wheezing x
Chills Chills x x x x x x x x x x
Hepatic failure Hepatic failure x
Agitation Agitation x
Onycholysis Onycholysis x x x x x x
Hyperphosphataemia Hyperphosphataemia x
Dermatitis bullous Dermatitis bullous x x x x x x
Hepatic function abnormal Hepatic function abnormal x x x x
Leukocytoclastic vasculitis Allergic cutaneous angiitis x x x x x x x
Blood creatinine increased Creatinine increased x
Crystalluria Crystalluria x x
Swelling face Swelling face x
Electrolyte imbalance Electrolyte abnormality x
Blood electrolytes abnormal Electrolyte abnormality x
Hypomagnesaemia Hypomagnesaemia x
Injection site reaction Injection site reaction x
Liver injury Hepatocellular injury x
Hepatic necrosis Hepatic necrosis x x x x x x x x x x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Metabolic acidosis Metabolic acidosis x
Abdominal pain upper Stomach ache x
Muscle twitching Muscle twitching x
Chest discomfort Chest tightness x
Renal impairment Function kidney decreased x
Nocturnal emission Nocturnal emission x x
Granulomatous liver disease Hepatitis granulomatous x x x x x x x x x
Hepatotoxicity Hepatotoxicity x
Skin exfoliation Skin exfoliation x x x
Skin scaly x
Oropharyngeal discomfort Throat sore x
Oropharyngeal pain Throat sore x
Sepsis Sepsis x
Aplasia Aplasia x
Hepatobiliary disease Hepatobiliary disease x
Mucosal inflammation Mucosal inflammation x
Abdominal distension Enlargement abdomen x
Paralysis Paralysis x x x x
Fluid overload Fluid overload x
Vasculitis necrotising Angiitis necrotising x x x x x x
Cardio-respiratory arrest Cardio-respiratory arrest x
Mental status changes Mental status changes x
Vasculitis gastrointestinal Vasculitis gastrointestinal x
Respiratory failure Respiratory failure x
Ageusia Ageusia x x x x x x
Gout Gout attack x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Allopurinol

Side effects:90
Source:FDA Structured Product Label

ALLOPURINOL / ALLOPRIN

Side effects:46
Source:Health Canada

ALLOPURINOL / Allopurinol, Tablet

Side effects:63
Source:Medsafe

Allopurinol / Progout

Side effects:56
Source:medicines.org.au

Allopurinol / ALLOPURINOL

Side effects:58
Source:medicines.org.au

ALLOPURINOL

Side effects:93
Source:FDA Structured Product Label

Allopurinol

Side effects:96
Source:FDA Structured Product Label

ALLOPURINOL

Side effects:97
Source:FDA Structured Product Label

ALLOPURINOL

Side effects:97
Source:FDA Structured Product Label

ALLOPURINOL

Side effects:97
Source:FDA Structured Product Label

allopurinol

Side effects:97
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label