Allopurinol

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Agranulocytosis def postmarketing, rare x x x x x x
Albuminuria def postmarketing x x x x x
Amblyopia def postmarketing x x x x x
Amnesia def postmarketing x x x x x
Anaemia def postmarketing x x x x x x x
Aplastic anaemia def postmarketing x x x x x x
Haemolytic anaemia def postmarketing x x x x x
Anorexia def postmarketing x x x x x
Asthenia def postmarketing x x x x x
Asthma def postmarketing x x x x x
Bronchospasm def postmarketing x x x x x
Confusional state def postmarketing x x x x x
Conjunctivitis def postmarketing x x x x x
Dizziness def postmarketing x x x x x
Oedema def postmarketing x x x x x x
Body temperature increased def rare x x x x x x x
Furunculosis def postmarketing x x x x x
Gastrointestinal haemorrhage def postmarketing x x x x x x
Gynaecomastia def postmarketing x x x x x
Haematuria def postmarketing x x x x x x
Haemorrhage def postmarketing x x x x x x x
Hypercalcaemia def postmarketing x x x x x x
Hyperlipidaemia def postmarketing x x x x x
Hypersensitivity def rare x x x x x x x
Infertility def postmarketing x x x x x
Iritis def postmarketing x x x x x
Lymphocytosis def postmarketing x x x x x
Nephritis def postmarketing x x x x x
Neuritis def postmarketing x x x x x x
Optic neuritis def postmarketing x x x x x
Pancreatitis def postmarketing x x x x x
Pancytopenia def postmarketing x x x x x x
Pericarditis def postmarketing x x x x x
Pharyngitis def postmarketing x x x x x x
Retinitis def postmarketing x x x x x
Rhinitis def postmarketing x x x x x
Stomatitis def postmarketing x x x x x
Sweating def postmarketing x x x x x
Swelling def postmarketing x x x x x x
Thrombophlebitis def postmarketing x x x x x x
Tinnitus def postmarketing x x x x
Angiopathy def postmarketing x x x x
Vasculitis def rare x x x x x x
Vasodilation def postmarketing x x x x x
Vertigo def postmarketing x x x x x
Peripheral vascular disorder def postmarketing x x x
Chills def rare x x x x x x x
Footdrop postmarketing x x x x x
Cataract def postmarketing x x x x x
Tongue oedema postmarketing x x x x x
Reticulocytosis def postmarketing x x x x x
Malaise def postmarketing x x x x x
Myalgia def postmarketing x x x x x x
Tenderness def rare x
Salivary gland swelling postmarketing x x x x x
Erectile dysfunction def postmarketing x x x x x
Throat sore def rare x
Pancreatitis haemorrhagic postmarketing x x x x
Bradycardia def postmarketing x x x x x x
Lymphadenopathy def postmarketing x x x x x
Skin oedema postmarketing x x x x x
Face oedema def postmarketing x x x x
Insomnia def postmarketing x x x x x
Abdominal pain def x x x x x
Acidosis def x
Lactic acidosis def x
Ageusia def x x x x
Alopecia def x x x x x x x
Apnoea def x
Arthralgia def x x x x x x
Blast cell crisis def x
Cardiovascular disorder def x
Cellulitis def x
Cerebral infarction def x
Coma def x
Constipation def x
Dermatitis def x x x x x x
Dermatitis exfoliative def x x x x x x
Dermatitis atopic def x
Diarrhoea def x x x x x x x
Disseminated intravascular coagulation def x
Drowsiness def x
Dyspepsia def x x x x x x
Dyspnoea def x
Dysuria def x
Ecchymosis def x x x x x x
Eczema def x x x x x
Eosinophilia def x x x x x x
Toxic epidermal necrolysis def x x x x x
Epistaxis def x x x x x
Erythema multiforme def x x x x x
Rash def x x x x x x x
Flatulence def x
Flushing def x
Gastritis def x x x x x
Glycosuria def x
Headache def x x x x x x x
Cardiac arrest def x
Cardiac failure def x
Hepatitis def x x x x x x
Hepatomegaly def x x x x x x
Hyperbilirubinaemia def x x x x x x
Hyperglycaemia def x
Hyperkalaemia def x
Hypernatraemia def x
Hypertension def x
Hypocalcaemia def x
Hypokalaemia def x
Hyponatraemia def x
Hypotension def x
Infarction def x
Infection def x
Intestinal obstruction def x
Jaundice def x x x x x x x
Jaundice cholestatic def x x x x x x
Renal failure acute def x
Leukocytosis def x x x x x
Leukopenia def x x x x x x
Lichen unspecified def x x x x x
Lichen planus def x x x x x
Hypotonia def x
Myopathy def x x x x x
Myoclonus def x
Nausea def x x x x x x x
Necrosis def x x x x x x
Neutropenia def x
Numbness def x
Obstruction def x
Oliguria def x
Pain def x x x x x x x
Paraesthesia def x x x x x
Neuropathy peripheral def x x x x x
Proctitis def x
Pruritus def x x x x x x x
Pulmonary embolism def x
Purpura def x x x x x
Renal failure def x x x x x x x
Acute respiratory distress syndrome def x
Seizures def x
Shock def x
Septic shock def x
Splenomegaly def x
Status epilepticus def x
Stevens-Johnson syndrome def x x
Gastric disorder def x
Cerebrovascular accident def x
Thrombocytopenia def x x x x x x x
Tremor def x
Tumour lysis syndrome def x
Ulcer def x
Erythema def x x x x x x
Uremia def x x x x x
Urinary tract infection def x
Urticaria def x x x x x x x
Ventricular fibrillation def x
Vomiting def x x x x x x x
Water intoxication def x
Weight increased def x
Wheezing def x
Hepatic failure def x
Agitation def x
Onycholysis def x x x x x
Hyperphosphataemia def x
Dermatitis bullous def x x x x x
Allergic cutaneous angiitis def x x x x x
Creatinine increased def x
Swelling face x
Electrolyte abnormality x
Necrolysis epidermal x x x x x
Hypomagnesaemia def x
Injection site reaction def x
Bone marrow depression def x
Hepatic necrosis def x x x x x
Metabolic acidosis def x
Stomach ache def x
Blood urine x
Muscle twitching def x
Cardiac fibrillation x
Chest tightness x
Function kidney decreased x
Ache def x
Convulsions generalised def x
Hepatitis granulomatous x x x x
Sepsis def x
Aplasia x
Eruption x x x x x
Mucosal inflammation def x
Enlargement abdomen def x
Dystonia def x
Skin scaly x
Rash maculo-papular def x x x
Neuropathy def x x x x x
Tarry stools x
Paralysis def x
Fluid overload def x
Angiitis necrotising def x x x x x
Cardio-respiratory arrest def x
Sweating increased x
Intoxication x
Mental status changes x
Respiratory failure def x
Cytolysis def x
Insufficiency renal def x x x x x
Embolus def x
Weakness def x
Tingling sensation def x
Gout attack x x x x x
Somnolence def x x x x x
Indication Labels
Anguish def x
Arthritis def x
Blood disorder def x
Calculus of kidney def x
Disease progression def x
Gout def x x x x x x
Gout acute x
Gouty arthritis def x
Gouty tophus x x x x x
Hyperuricaemia def x x x x x x
Hyperuricosuria x
Inflammation def x
Joint destruction x x x x x
Leukaemia def x x x x x x x
Lymphoma def x x x x x x x
Metaplasia def x
Myeloid metaplasia x
Neoplasm def x x
Neoplasm malignant def x x x x x x x
Nephropathy def x x x x x x
Polycythaemia def x
Polycythaemia vera def x
Secondary gout x x x x x
Solid tumour def x
Urate x
Urate nephropathy x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: M04AA01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. Allopurinol : 102 side effects (FDA XML label)
  2. ALLOPURINOL / ALLOPRIN : 54 side effects (Health Canada)
  3. Allopurinol : 108 side effects (FDA XML label)
  4. ALLOPURINOL : 111 side effects (FDA XML label)
  5. ALLOPURINOL : 111 side effects (FDA XML label)
  6. ALLOPURINOL : 115 side effects (FDA XML label)
  7. allopurinol : 115 side effects (FDA XML label)