Myeloproliferative disorder

Definition: Conditions which cause proliferation of hemopoietically active tissue or of tissue which has embryonic hemopoietic potential. They all involve dysregulation of multipotent MYELOID PROGENITOR CELLS, most often caused by a mutation in the JAK2 PROTEIN TYROSINE KINASE.

Synonyms (terms occurring on more labels are shown first): myeloproliferative disorders, myeloproliferative disease, myeloproliferative disorder