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Hydroxyurea

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX05

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Azoospermia very common x
Neutropenia very common x x
Oligospermia very common x
Bone marrow depression very common x x x x x x x x
Reticulocytopenia very common x
Anaemia common x x x x x x x x x
Mucosal inflammation common x x x x x x x x x
Thrombocytopenia common, 1-5% x x x x x x x x x
Constipation 1-5% x x x x x x x x x
Stomatitis 1-5% x x x x x x x x x
Headache common, 1% x x x x x x x x x x
Alopecia uncommon, 1-5% x x x x x x x x x x
Rash uncommon x x x x
Nausea uncommon x x x x x x x x x x
Melanonychia uncommon x x
Dizziness uncommon, 1% x x x x x x x x x x
Dysuria 1% x x x x x x x x x
Hallucination 1% x x x x x x x x x
Convulsion 1% x x x x x x x x x
Hyperuricaemia 1% x
Leg ulcer rare x x
Hepatic enzyme increased rare x
Amenorrhoea x
Anaemia megaloblastic x
Anorexia x x x x x x x x x
Asthenia x x x x x x x
Blepharitis x
Blister x
Breast disorder x
Skin cancer x x x x x x x x x
Infection x
Dermatitis x
Dermatomyositis x x x x x x x
Diarrhoea x x x x x x x x x
Drowsiness x x x x x x x x x
Dyspnoea x x x x x x x x
Oedema x x x x x x
Fatigue x
Body temperature increased x x x x x x x x x
Fibrosis x x x x
Folate deficiency x
Gangrene x x x x x x
Gastrointestinal disorder x
Haemorrhage x x
Hypersensitivity x
Renal failure acute x
Leukaemia x
Chronic myeloid leukaemia x
Leukopenia x x x x x x x
Neoplasm x x x x
Nervous system disorder x
Pain x x x
Pancreatitis x x x x x x x
Neuropathy peripheral x x x x x x
Pulmonary oedema x
Pulmonary fibrosis x x x x
Radiation injury x
Dermatitis radiation NOS x
Skin ulcer x x x x x x x
Ulcer x x x x x x
Erythema x x x x x
Ureteric obstruction x
Angiopathy x
Vomiting x x x x x x x x x x
Weight increased x x
Erythema infectiosum x x
Chills x x x x x x x x
Skin atrophy x x x x x x x
Blood urea increased x
Creatinine increased x
Hypomagnesaemia x
Skin necrosis x
Skin hyperpigmentation x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x
Aphagia x x
Malaise x x x x x x x
Distress x x x x x x x
Digestion impaired x x
Disorientation x x x x x x x x x
Discomfort x x
Tenderness x
Hepatotoxicity x x x x x x x
Lung infiltration x x x x x x x x
Serum iron decreased x
Skin exfoliation x
Gastrointestinal ulcer x
Erythema facial x x x x x x x x
Hepatobiliary disease x
Solid tumour x x
Eruption x
Papule x x x x x x x x
Atrophy x
Gastric irritation x x x x x x x
Platelet count decreased x x
Lupus erythematosus x
Rash maculo-papular x x x x x x x x x
Gastrointestinal symptom NOS x x x x x x x
Face oedema x
Intoxication x
Febrile neutropenia x
Infestation NOS x
Blood and lymphatic system disorders x
Myelosuppression x x
Leukemia secondary x
Nail pigmentation x
Splenic sequestration x
Recall phenomenon x
Urine output x
Hepatic insufficiency x
Metastatic disease x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

hydroxycarbamide / hydroxycarbamide

Side effects:39
Source:EMA

HYDROXYUREA / APO-HYDROXYUREA

Side effects:30
Source:Health Canada

hydroxyurea

Side effects:44
Source:FDA Structured Product Label

hydroxyurea capsules / HYDREA®

Side effects:38
Source:FDA

hydroxyurea / HYDREA

Side effects:41
Source:FDA

hydroxyurea

Side effects:43
Source:FDA Structured Product Label

Hydroxyurea / HYDREA

Side effects:42
Source:medicines.org.au

Hydrea / Hydrea, Capsule

Side effects:46
Source:Medsafe

HYDROXYUREA / HYDREA CAP 500MG

Side effects:52
Source:Health Canada

Hydroxyurea

Side effects:65
Source:BC Cancer

Color scheme:

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    frequent (1% to 100%)
    infrequent (0.1% to 1%)
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    postmarketing
    0%
    no frequency information
    not found on label