Hydroxyurea

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Aggression def x
Alopecia def x x x x x
Anaemia megaloblastic def x
Anorexia def x x x x x
Asthenia def x x x
Blepharitis def x
Skin cancer def x x x x
Constipation def x x x x x
Convulsion def x x x x
Dermatitis def x
Dermatomyositis def x x x x
Diarrhoea def x x x x x
Dizziness def x x x x x
Drowsiness def x x x x x
Dyspnoea def x x x x
Dysuria def x x x x x
Oedema def x x x x
Rash def x x x x x
Fatigue def x
Body temperature increased def x x x x
Fibrosis def x x x x
Folate deficiency def x
Gangrene def x x x
Hallucination def x x x x x
Headache def x x x x x
Haemolysis def x
Haemorrhage def x
Hypersensitivity def x
Ichthyosis def x x x
Infection def x
Inflammation def x
Renal failure acute def x
Leg ulcer def x
Leukopenia def x x x x x
Nausea def x x x x x
Necrosis def x
Neutropenia def x x
Obstruction def x
Pain def x
Pancreatic disorder def x
Pancreatitis def x x x x
Neuropathy peripheral def x x x
Pigmentation def x
Pulmonary fibrosis def x x x
Renal failure def x
Seizures def x
Skin ulcer def x x x
Stomatitis def x x x x x
Thrombocytopenia def x x x x x
Ulcer def x x x x
Erythema def x x x x x
Ureteric obstruction def x
Uric acid level increased x
Vomiting def x x x x x
Weight increased def x
Chills def x x x x
Skin atrophy def x x x x
Blood urea increased x
Creatinine increased def x
Renal tubular disorder def x x x x x
Bone marrow depression def x x x x
Skin necrosis x
Skin hyperpigmentation def x x x x
Malaise def x x x
Disorientation x x x x x
Lung infiltration x x x x
Serum iron decreased x
Hepatic enzyme increased x
Skin exfoliation x x x x
Erythema facial x x x x
Eruption x
Papule def x x x x
Mucosal inflammation def x x x x
Atrophy def x x x x
Gastric irritation x x x
Lupus erythematosus def x
Rash maculo-papular def x x x x x
Gastrointestinal symptom NOS x x x x
Neuropathy def x x x
Face oedema def x
Macrocytosis x
Intoxication x
Hyperuricaemia def x
Febrile neutropenia def x
Second primary malignancy def x
Myelosuppression def x
Leukemia secondary x
Melanonychia x
Urine output x
Cytolysis def x
Indication Labels
Anaemia def x
Carcinoma def x x x x
Cervix carcinoma def x
Chronic myeloid leukaemia def x x x x x
Head and neck cancer def x
Leukaemia def x x x x x
Lung neoplasm malignant def x
Lymphoid interstitial pneumonia def x x x x
Malignant melanoma def x x x x x
Myeloid leukaemia def x x x x x
Myeloproliferative disorder def x
Neoplasm def x x x x
Neoplasm malignant def x
Ovarian cancer def x
Ovarian disorder def x x x
Ovarian epithelial cancer def x x x
Sickle cell anaemia def x
Uterine cancer def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX05

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. HYDROXYUREA / HYDREA CAP 500MG : 3 side effects (Health Canada)
  2. HYDROXYUREA / APO-HYDROXYUREA : 26 side effects (Health Canada)
  3. hydroxyurea : 48 side effects (FDA XML label)
  4. HYDROXYUREA / HYDREA : 47 side effects (Drugs@FDA)
  5. HYDROXYUREA / HYDREA : 48 side effects (Drugs@FDA)
  6. Hydroxyurea : 73 side effects (BC Cancer)