MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
Neutropenia
|
Neutropenia
|
postmarketing — 33.4% - 79%
|
3.43% - 17.9%
|
x
|
x
|
x
|
x
|
x
|
Diarrhoea
|
Diarrhoea
|
postmarketing — 1.7% - 60.1%
|
0.571% - 27.4%
|
x
|
x
|
x
|
x
|
x
|
Loose stools
|
common
|
|
x
|
|
x
|
x
|
x
|
Muscle spasms
|
Cramp muscle
|
very common, 15.2% - 33.4%
|
6% - 21.1%
|
x
|
x
|
x
|
x
|
x
|
Muscle spasms
|
postmarketing, 0.746% - 16.7%
|
|
x
|
x
|
x
|
|
x
|
Thrombocytopenia
|
Thrombocytopenia
|
postmarketing — 12.2% - 74%
|
3% - 10.6%
|
x
|
x
|
x
|
x
|
x
|
Tremor
|
Tremor
|
postmarketing, 21.2%
|
7.4% - 7.43%
|
x
|
x
|
x
|
|
x
|
Constipation
|
Constipation
|
postmarketing — 0.746% - 40.5%
|
0.286% - 21.1%
|
x
|
x
|
x
|
x
|
x
|
Nausea
|
Nausea
|
postmarketing — 0.746% - 29.9%
|
0.571% - 21.4%
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
Fatigue
|
postmarketing — 4.7% - 43.9%
|
4.86% - 41.7%
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
common, 2.99% - 14.2%
|
|
x
|
|
x
|
x
|
x
|
Fatigue
|
Fatigue
|
postmarketing — 4.7% - 43.9%
|
4.86% - 41.7%
|
x
|
x
|
x
|
x
|
x
|
Vision blurred
|
Vision blurred
|
postmarketing, 17.3%
|
11.4%
|
x
|
x
|
x
|
|
x
|
Pruritus
|
Pruritus
|
postmarketing — 0.746% - 44.6%
|
4.5% - 5.14%
|
x
|
x
|
x
|
x
|
x
|
Decreased appetite
|
Anorexia
|
common, 15.6%
|
9.7% - 9.71%
|
x
|
|
x
|
x
|
x
|
Decreased appetite
|
postmarketing, 0.746% - 14.2%
|
4%
|
|
x
|
x
|
|
x
|
Dermatitis
|
Rash
|
postmarketing — 1.49% - 37.8%
|
1.5% - 9.43%
|
|
x
|
x
|
x
|
x
|
Rash
|
Rash
|
postmarketing — 1.49% - 37.8%
|
1.5% - 9.43%
|
|
x
|
x
|
x
|
x
|
Oedema peripheral
|
Oedema peripheral
|
postmarketing — 0% - 26.3%
|
7.5% - 21.1%
|
x
|
x
|
x
|
x
|
x
|
Body temperature increased
|
Body temperature increased
|
postmarketing — 2.24% - 27.5%
|
6% - 23.4%
|
x
|
x
|
x
|
x
|
x
|
Intermittent fever
|
|
|
|
|
|
x
|
x
|
Nasopharyngitis
|
Nasopharyngitis
|
postmarketing — 11.6% - 23.5%
|
7.5% - 17.1%
|
x
|
x
|
x
|
x
|
x
|
Rhinorrhoea
|
|
|
x
|
|
|
|
|
Upper respiratory tract infection
|
Upper respiratory tract infection
|
postmarketing, 0% - 24.6%
|
15.7%
|
|
x
|
x
|
x
|
x
|
Pain in extremity
|
Pain in extremity
|
common, 11.9%
|
9.1% - 9.14%
|
|
|
x
|
x
|
x
|
Foot pain
|
common
|
|
|
|
x
|
|
|
Bronchitis
|
Bronchitis
|
postmarketing — 11.3% - 11.6%
|
4.5% - 8.6%
|
x
|
x
|
x
|
x
|
x
|
Hypoaesthesia
|
Hypoaesthesia
|
common, 10.2%
|
7.1% - 7.14%
|
|
|
x
|
|
x
|
Dysgeusia
|
Dysgeusia
|
postmarketing — 15.3%
|
9.7% - 9.71%
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
Dizziness
|
postmarketing — 1.98% - 23.2%
|
0.857% - 16.9%
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
postmarketing, 2.83%
|
0.857%
|
x
|
x
|
x
|
x
|
x
|
Anaemia
|
Anaemia
|
postmarketing — 6.1% - 31.4%
|
5.71% - 23.7%
|
x
|
x
|
x
|
x
|
x
|
Abdominal pain
|
Abdominal pain
|
postmarketing — 3.73% - 10.9%
|
6% - 6.29%
|
|
x
|
x
|
x
|
x
|
Gastrointestinal pain
|
Abdominal pain
|
postmarketing — 3.73% - 10.9%
|
6% - 6.29%
|
|
x
|
x
|
x
|
x
|
Bowel spasm
|
uncommon
|
|
x
|
|
x
|
|
|
Dry skin
|
Dry skin
|
postmarketing — 9.35% - 10.1%
|
1.5% - 4%
|
x
|
x
|
x
|
x
|
x
|
Respiratory tract infection
|
Respiratory tract infection
|
common, 13.8%
|
3%
|
|
|
x
|
x
|
x
|
Pharyngitis
|
Pharyngitis
|
postmarketing — 13.6%
|
9.4% - 9.43%
|
x
|
x
|
x
|
x
|
x
|
Cough
|
Cough
|
postmarketing — 0.746% - 28.4%
|
6%
|
x
|
x
|
x
|
x
|
x
|
Vomiting
|
Vomiting
|
postmarketing — 0.746% - 12.2%
|
9.4% - 9.43%
|
x
|
x
|
x
|
x
|
x
|
Leukopenia
|
Leukopenia
|
very common, 3.97% - 14.9%
|
0.286% - 3%
|
x
|
|
x
|
x
|
x
|
Pneumonia
|
Pneumonia
|
postmarketing — 7.4% - 14.2%
|
5.43% - 8.3%
|
x
|
x
|
x
|
x
|
x
|
Hyperhidrosis
|
Sweating increased
|
common, 9.92%
|
7.14%
|
|
|
x
|
x
|
x
|
Hyperhidrosis
|
postmarketing
|
|
|
x
|
x
|
|
|
Sweating
|
|
|
x
|
|
|
|
|
Headache
|
Headache
|
postmarketing — 14.5%
|
7.5%
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea
|
Dyspnoea
|
postmarketing — 4.7% - 23.5%
|
8.9% - 17.1%
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea exacerbated
|
|
|
|
|
|
x
|
x
|
Back pain
|
Back pain
|
postmarketing — 1.49% - 25.8%
|
18.6%
|
|
x
|
x
|
x
|
x
|
Dysuria
|
Dysuria
|
common, 6.76%
|
|
x
|
|
x
|
x
|
x
|
Hypothyroidism
|
Primary hypothyroidism
|
common, 6.76%
|
|
|
|
x
|
x
|
x
|
Hypothyroidism
|
postmarketing
|
|
x
|
x
|
x
|
|
x
|
Primary hypothyroidism
|
Primary hypothyroidism
|
common, 6.76%
|
|
|
|
x
|
x
|
x
|
Abdominal distension
|
Abdominal distension
|
common
|
|
x
|
|
x
|
|
|
Agranulocytosis
|
Agranulocytosis
|
common
|
|
x
|
|
x
|
x
|
x
|
Alopecia
|
Alopecia
|
common
|
|
x
|
|
x
|
|
|
Anxiety
|
Anxiety
|
common
|
|
x
|
|
x
|
|
|
Conjunctivitis
|
Conjunctivitis
|
common
|
|
x
|
|
x
|
|
|
Flatulence
|
Flatulence
|
common
|
|
x
|
|
x
|
|
|
Hordeolum
|
Hordeolum
|
common
|
|
x
|
|
x
|
|
|
Pulmonary hypertension
|
Pulmonary hypertension
|
common
|
|
x
|
|
x
|
x
|
x
|
Eye pruritus
|
Eye pruritus
|
common
|
|
|
|
x
|
|
|
Nasal congestion
|
Nasal congestion
|
common
|
|
x
|
|
x
|
|
|
Night sweats
|
Night sweats
|
common
|
|
x
|
|
x
|
x
|
x
|
Paraesthesia
|
Paraesthesia
|
common
|
|
x
|
|
x
|
|
|
Petechiae
|
Petechiae
|
common
|
|
x
|
|
x
|
|
|
Polycythaemia
|
Polycythaemia
|
common
|
|
x
|
|
x
|
|
|
Prurigo
|
Prurigo
|
common
|
|
|
|
x
|
|
|
Skin lesion
|
Skin lesion
|
common
|
|
|
|
x
|
|
|
Erythema
|
Erythema
|
common
|
|
x
|
|
x
|
x
|
x
|
Weight decreased
|
Weight decreased
|
postmarketing — 0% - 19.5%
|
14.9%
|
x
|
x
|
x
|
|
x
|
Dry mouth
|
Dry mouth
|
postmarketing — 7.08%
|
3.71%
|
x
|
x
|
x
|
x
|
x
|
Stomatitis
|
Mouth ulceration
|
common
|
|
x
|
|
x
|
|
|
Stomatitis
|
postmarketing
|
|
x
|
x
|
x
|
|
|
Mouth ulceration
|
Mouth ulceration
|
common
|
|
x
|
|
x
|
|
|
Peripheral sensory neuropathy
|
Peripheral sensory neuropathy
|
common
|
|
|
|
x
|
|
|
Hypomagnesaemia
|
Hypomagnesaemia
|
postmarketing — 6.8%
|
2.86%
|
x
|
x
|
x
|
x
|
x
|
Aspartate aminotransferase increased
|
Aspartate aminotransferase increased
|
common
|
|
|
|
x
|
|
|
Alanine aminotransferase increased
|
Alanine aminotransferase increased
|
common, 8.11%
|
|
|
|
x
|
x
|
x
|
Polyneuropathy
|
Polyneuropathy
|
common
|
|
x
|
|
x
|
|
|
Rash macular
|
Rash macular
|
common
|
|
|
|
x
|
|
|
Dyspnoea exertional
|
Dyspnoea exertional
|
common
|
|
x
|
|
x
|
x
|
x
|
Abdominal discomfort
|
Abdominal discomfort
|
common
|
|
|
|
x
|
|
|
Upset stomach
|
uncommon
|
|
|
|
x
|
|
|
Gastrointestinal tract irritation
|
|
|
x
|
|
|
|
|
Rash erythematous
|
Rash erythematous
|
common
|
|
|
|
x
|
|
|
Blood creatinine increased
|
Blood creatinine increased
|
common
|
|
|
|
x
|
x
|
x
|
Dry eye
|
Dry eye
|
common
|
|
x
|
|
x
|
|
|
Local swelling
|
Peripheral swelling
|
common
|
|
|
|
x
|
x
|
x
|
Insomnia
|
Insomnia
|
common
|
|
x
|
|
x
|
x
|
x
|
Mood swings
|
Mood alteration NOS
|
common
|
|
x
|
|
x
|
|
|
Mood swings
|
postmarketing
|
|
|
x
|
|
|
x
|
Hypokalaemia
|
Hypokalaemia
|
postmarketing — 2.24% - 13.6%
|
1.43% - 6%
|
x
|
x
|
x
|
x
|
x
|
Oropharyngeal pain
|
Oropharyngeal pain
|
0% - 9.7%
|
|
|
|
|
|
x
|
Dehydration
|
Dehydration
|
postmarketing, 2.99% - 7.46%
|
4.29%
|
x
|
x
|
x
|
x
|
x
|
Deep vein thrombosis
|
Deep vein thrombosis
|
postmarketing — 3.73% - 9.35%
|
3.14% - 4.29%
|
x
|
x
|
x
|
x
|
x
|
Lymphopenia
|
Lymphopenia
|
2.83% - 7.46%
|
1.14% - 1.43%
|
|
|
|
|
x
|
Neuropathy peripheral
|
Neuropathy
|
uncommon, 6.52%
|
3.71%
|
x
|
|
x
|
|
x
|
Neuropathy peripheral
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Endocrine disorder
|
Endocrine disorder
|
postmarketing, 6.76%
|
|
|
x
|
x
|
x
|
x
|
Hypertension
|
Hypertension
|
postmarketing — 6.08% - 7.93%
|
5.71%
|
x
|
x
|
x
|
x
|
x
|
Arthralgia
|
Arthralgia
|
postmarketing — 1.49% - 8.21%
|
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal discomfort
|
Arthralgia
|
postmarketing — 1.49% - 8.21%
|
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Febrile neutropenia
|
Febrile neutropenia
|
postmarketing — 1.7% - 6%
|
0%
|
x
|
x
|
x
|
x
|
x
|
Bone pain
|
Bone pain
|
postmarketing — 1.13% - 13.6%
|
0% - 11.1%
|
|
x
|
x
|
|
x
|
Hypotension
|
Hypotension
|
postmarketing — 2.99% - 7.08%
|
4.29%
|
x
|
x
|
x
|
x
|
x
|
Squamous cell carcinoma of skin
|
Squamous cell carcinoma of skin
|
2.99%
|
|
|
|
|
|
x
|
Palpitations
|
Palpitations
|
uncommon, 5.41%
|
|
x
|
|
x
|
x
|
x
|
Depression
|
Depression
|
postmarketing — 2.83%
|
1.71%
|
|
x
|
x
|
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing, 5.41%
|
|
|
x
|
x
|
x
|
x
|
Infection
|
Infection
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Oedema
|
Oedema
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Pitting edema
|
|
|
x
|
|
|
|
|
Pancytopenia
|
Pancytopenia
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Myelosuppression
|
uncommon
|
|
x
|
|
x
|
|
|
Bone marrow depression
|
|
|
|
|
|
x
|
x
|
Tinnitus
|
Tinnitus
|
postmarketing, common
|
|
x
|
x
|
x
|
|
|
Urticaria
|
Urticaria
|
postmarketing, common
|
|
x
|
x
|
x
|
|
|
Chills
|
Rigors
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Chills
|
|
|
|
|
|
|
x
|
Hyponatraemia
|
Hyponatraemia
|
common, 2.24%
|
|
x
|
|
x
|
|
x
|
Pulmonary embolism
|
Pulmonary embolism
|
postmarketing — 1.49% - 3.97%
|
0.857%
|
x
|
x
|
x
|
x
|
x
|
Hypocalcaemia
|
Hypocalcaemia
|
postmarketing, 1.49% - 8.78%
|
1.71% - 2.86%
|
x
|
x
|
x
|
|
x
|
Hypoxia
|
Hypoxia
|
1.49% - 2.24%
|
|
|
|
|
x
|
x
|
General physical health deterioration
|
General physical health deterioration
|
1.49% - 2.24%
|
|
|
|
|
|
x
|
Atrial fibrillation
|
Atrial fibrillation
|
postmarketing, 3.12% - 3.68%
|
0.571% - 1.14%
|
x
|
x
|
x
|
x
|
x
|
Fibrillation atrial aggravated
|
|
|
|
|
|
x
|
x
|
Bacteraemia
|
Bacteraemia
|
1.49%
|
|
x
|
|
x
|
x
|
x
|
Cellulitis
|
Cellulitis
|
uncommon, 1.49% - 2.24%
|
|
x
|
|
x
|
x
|
x
|
Pleural effusion
|
Pleural effusion
|
uncommon, 1.49% - 7.46%
|
|
x
|
|
x
|
x
|
x
|
Renal failure
|
Renal failure
|
postmarketing, 1.49% - 3.73%
|
|
|
x
|
x
|
x
|
x
|
Urinary tract infection
|
Urinary tract infection
|
uncommon, 1.42% - 8.5%
|
0.286% - 5.43%
|
|
|
x
|
x
|
x
|
Muscular weakness
|
Muscular weakness
|
postmarketing — 1.49% - 5.97%
|
2.86%
|
|
x
|
x
|
|
x
|
Staphylococcal bacteraemia
|
Staphylococcal bacteraemia
|
1.49%
|
|
|
|
|
|
x
|
Respiratory distress
|
Respiratory distress
|
postmarketing — 1.13% - 1.49%
|
0%
|
x
|
x
|
x
|
x
|
x
|
Shock
|
Syncope
|
postmarketing, 2.83%
|
0.857%
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
Syncope
|
postmarketing, 2.83%
|
0.857%
|
x
|
x
|
x
|
x
|
x
|
Syncope vasovagal
|
|
|
x
|
|
|
|
|
Loss of consciousness
|
Syncope
|
postmarketing, 2.83%
|
0.857%
|
x
|
x
|
x
|
x
|
x
|
Cataract
|
Cataract unilateral
|
1.42%
|
0%
|
|
|
x
|
|
x
|
Cataract
|
postmarketing, 1.7%
|
0.286%
|
|
x
|
x
|
|
x
|
Hypophosphataemia
|
Hypophosphataemia
|
postmarketing, 2.55%
|
0%
|
|
x
|
x
|
|
x
|
Cardiac failure congestive
|
Cardiac failure congestive
|
postmarketing — 1.42%
|
0% - 0.286%
|
x
|
x
|
x
|
x
|
x
|
Amenorrhoea
|
Amenorrhoea
|
uncommon
|
|
|
|
x
|
|
|
Aortic valve stenosis
|
Aortic valve stenosis
|
uncommon
|
|
|
|
x
|
|
|
Candida infection
|
Oral candidiasis
|
uncommon
|
|
x
|
|
x
|
|
|
Oral candidiasis
|
Oral candidiasis
|
uncommon
|
|
x
|
|
x
|
|
|
Chest pain
|
Chest pain
|
postmarketing — 8.22%
|
5.71%
|
|
x
|
x
|
x
|
x
|
Clostridial infection
|
Clostridial infection
|
uncommon
|
|
|
|
x
|
x
|
x
|
Drug eruption
|
Drug eruption
|
uncommon
|
|
|
|
x
|
|
|
Dyspepsia
|
Dyspepsia
|
postmarketing — common
|
|
x
|
x
|
x
|
|
|
Gastroenteritis
|
Gastroenteritis
|
uncommon
|
|
x
|
|
x
|
x
|
x
|
Gynaecomastia
|
Gynaecomastia
|
uncommon
|
|
|
|
x
|
|
|
Dysphonia
|
Hoarseness
|
uncommon
|
|
x
|
|
x
|
|
x
|
Lethargy
|
Lethargy
|
postmarketing — 6.8%
|
2.29%
|
x
|
x
|
x
|
|
x
|
Hypotonia
|
Hypotonia
|
uncommon
|
|
|
|
x
|
|
|
Muscle relaxant therapy
|
Hypotonia
|
uncommon
|
|
|
|
x
|
|
|
Nervousness
|
Nervousness
|
uncommon
|
|
|
|
x
|
|
|
Tension
|
Nervousness
|
uncommon
|
|
|
|
x
|
|
|
Osteoporosis
|
Osteoporosis
|
uncommon
|
|
x
|
|
x
|
|
|
Lobar pneumonia
|
Lobar pneumonia
|
uncommon
|
|
|
|
x
|
x
|
x
|
Rhinitis
|
Rhinitis
|
uncommon
|
|
x
|
|
x
|
x
|
x
|
Sinusitis
|
Sinusitis
|
postmarketing — 7.37%
|
4.57%
|
x
|
x
|
x
|
x
|
x
|
Speech disorder
|
Speech disorder
|
uncommon
|
|
|
|
x
|
|
|
Cerebrovascular accident
|
Cerebrovascular accident
|
postmarketing — 1.98%
|
0.857%
|
|
x
|
x
|
x
|
x
|
Tachycardia
|
Tachycardia
|
postmarketing — 1.7%
|
0.286%
|
x
|
x
|
x
|
|
x
|
Varicose vein
|
Varicose vein
|
uncommon
|
|
|
|
x
|
|
|
Acute febrile neutrophilic dermatosis
|
Acute febrile neutrophilic dermatosis
|
uncommon
|
|
x
|
|
x
|
x
|
x
|
Pollakiuria
|
Micturition urgency
|
uncommon
|
|
|
|
x
|
|
|
Micturition urgency
|
Micturition urgency
|
uncommon
|
|
|
|
x
|
|
|
Burning sensation
|
Burning sensation
|
uncommon
|
|
x
|
|
x
|
|
|
Agitation
|
Agitation
|
uncommon
|
|
x
|
|
x
|
|
|
Swelling face
|
Swelling face
|
uncommon
|
|
|
|
x
|
|
|
Injection site haemorrhage
|
Injection site haemorrhage
|
uncommon
|
|
|
|
x
|
|
|
Injection site bruising
|
uncommon
|
|
|
|
x
|
|
|
Sensory disturbance
|
Sensory disturbance
|
uncommon
|
|
x
|
|
x
|
|
|
Skin irritation
|
Skin irritation
|
uncommon
|
|
|
|
x
|
|
|
Eyelid oedema
|
Eyelid oedema
|
uncommon
|
|
x
|
|
x
|
|
|
Joint stiffness
|
Joint stiffness
|
uncommon
|
|
|
|
x
|
|
|
Colitis ischaemic
|
Colitis ischaemic
|
uncommon
|
|
|
|
x
|
x
|
x
|
Skin fissures
|
Skin fissures
|
uncommon
|
|
|
|
x
|
|
|
Areflexia
|
Areflexia
|
uncommon
|
|
|
|
x
|
|
|
Abnormal dreams
|
Abnormal dreams
|
uncommon
|
|
|
|
x
|
|
|
Dry throat
|
Dry throat
|
uncommon
|
|
|
|
x
|
|
|
Eye irritation
|
Eye irritation
|
uncommon
|
|
|
|
x
|
|
|
Lung infiltration
|
Lung infiltration
|
uncommon
|
|
|
|
x
|
x
|
x
|
Perirectal abscess
|
Perirectal abscess
|
uncommon
|
|
|
|
x
|
x
|
x
|
Blood bilirubin increased
|
Blood bilirubin increased
|
uncommon
|
|
|
|
x
|
|
|
Aneurysm
|
Arterial aneurysm
|
uncommon
|
|
x
|
|
x
|
|
|
Eye discharge
|
Eye discharge
|
uncommon
|
|
|
|
x
|
|
|
Decreased interest
|
Decreased interest
|
uncommon
|
|
|
|
x
|
|
|
Orbital oedema
|
Orbital oedema
|
uncommon
|
|
|
|
x
|
|
|
Pruritus generalised
|
Pruritus generalised
|
uncommon
|
|
|
|
x
|
|
|
Injection site bruising
|
Injection site bruising
|
uncommon
|
|
|
|
x
|
|
|
Regurgitation
|
Regurgitation of food
|
uncommon
|
|
|
|
x
|
|
|
Face oedema
|
Face oedema
|
uncommon
|
|
|
|
x
|
|
|
Lip dry
|
Lip dry
|
uncommon
|
|
|
|
x
|
|
|
Sensation of heaviness
|
Sensation of heaviness
|
uncommon
|
|
|
|
x
|
|
|
Blood uric acid increased
|
Hyperuricaemia
|
uncommon
|
|
|
|
x
|
|
|
Hyperuricaemia
|
Hyperuricaemia
|
uncommon
|
|
|
|
x
|
|
|
Klebsiella sepsis
|
Klebsiella sepsis
|
uncommon
|
|
x
|
|
x
|
x
|
x
|
Lip haemorrhage
|
Lip haemorrhage
|
uncommon
|
|
|
|
x
|
|
|
Sleep disorder
|
Sleep disorder
|
uncommon
|
|
x
|
|
x
|
|
|
Mucosal dryness
|
Mucosal dryness
|
uncommon
|
|
|
|
x
|
|
|
Post procedural haemorrhage
|
Post procedural haemorrhage
|
uncommon
|
|
|
|
x
|
x
|
x
|
Ear discomfort
|
Ear discomfort
|
uncommon
|
|
x
|
|
x
|
|
|
Lymphoma cutis
|
Lymphoma cutis
|
uncommon
|
|
|
|
x
|
|
|
Rhinitis allergic
|
Rhinitis allergic
|
uncommon
|
|
x
|
|
x
|
|
|
Basal cell carcinoma
|
Basal cell carcinoma
|
postmarketing, uncommon
|
|
|
x
|
x
|
|
x
|
Musculoskeletal pain
|
Musculoskeletal pain
|
postmarketing, uncommon
|
|
|
x
|
x
|
|
|
Pain
|
Pain
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
Influenza like illness
|
Influenza like illness
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
|
|
Congenital anomaly
|
Congenital anomaly
|
postmarketing
|
|
|
x
|
|
|
|
Developmental delay
|
Congenital anomaly
|
postmarketing
|
|
|
x
|
|
|
|
Haemolytic anaemia
|
Haemolytic anaemia
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Autoimmune haemolytic anaemia
|
Autoimmune haemolytic anaemia
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Angioedema
|
Angioedema
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Arrhythmia
|
Arrhythmia
|
postmarketing
|
|
x
|
x
|
|
|
|
Ataxia
|
Ataxia
|
postmarketing
|
|
|
x
|
|
|
|
Atrial flutter
|
Atrial flutter
|
postmarketing
|
|
|
x
|
|
|
|
Mental disorder
|
Mental disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Coagulopathy
|
Coagulopathy
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Breast disorder
|
Breast disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Neoplasm malignant
|
Neoplasm malignant
|
postmarketing
|
|
x
|
x
|
|
x
|
x
|
Carcinoma
|
|
|
x
|
|
|
|
|
Skin cancer
|
Skin cancer
|
postmarketing
|
|
|
x
|
|
|
|
Transient ischaemic attack
|
Transient ischaemic attack
|
postmarketing
|
|
x
|
x
|
|
x
|
x
|
Cholestasis
|
Cholestasis
|
postmarketing
|
|
|
x
|
|
|
|
Colitis
|
Colitis
|
postmarketing
|
|
|
x
|
|
|
|
Connective tissue disorder
|
Connective tissue disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Contusion
|
Contusion
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
Cyst
|
Cyst
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Deafness
|
Deafness
|
postmarketing
|
|
|
x
|
x
|
|
|
Hearing impaired
|
postmarketing
|
|
|
x
|
x
|
|
|
Dysphagia
|
Dysphagia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
Ecchymosis
|
Ecchymosis
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Eczema
|
Eczema
|
postmarketing
|
|
|
x
|
|
|
|
Toxic epidermal necrolysis
|
Toxic epidermal necrolysis
|
postmarketing
|
|
|
x
|
x
|
|
|
Epistaxis
|
Epistaxis
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Eye disorder
|
Eye disorder
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Gastrointestinal haemorrhage
|
Gastrointestinal haemorrhage
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Gingival bleeding
|
Gingival bleeding
|
postmarketing
|
|
x
|
x
|
x
|
|
|
Cardiac failure
|
Cardiac failure
|
postmarketing
|
|
x
|
x
|
|
x
|
x
|
Haematoma
|
Haematoma
|
postmarketing
|
|
x
|
x
|
|
|
|
Haematuria
|
Haematuria
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Haemolysis
|
Haemolysis
|
postmarketing
|
|
|
x
|
x
|
|
|
Haemorrhagic disorder
|
Haemorrhagic disorder
|
postmarketing
|
|
|
x
|
|
|
|
Hepatitis toxic
|
Hepatitis toxic
|
postmarketing
|
|
|
x
|
|
|
x
|
Hyperglycaemia
|
Hyperglycaemia
|
postmarketing
|
|
|
x
|
|
|
|
Hypersensitivity
|
Hypersensitivity
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
Hyperthyroidism
|
Hyperthyroidism
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Immune system disorder
|
Immune system disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Ischaemia
|
Ischaemia
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Acute myeloid leukaemia
|
Acute myeloid leukaemia
|
postmarketing
|
|
|
x
|
|
x
|
x
|
AML progression
|
postmarketing
|
|
|
x
|
|
|
|
Acute leukaemia
|
Acute myeloid leukaemia
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Acute leukaemia
|
|
|
x
|
|
|
x
|
x
|
Liver disorder
|
Liver disorder
|
postmarketing
|
|
|
x
|
|
|
|
Hepatocellular injury
|
Liver disorder
|
postmarketing
|
|
|
x
|
|
|
|
Foetor hepaticus
|
Liver disorder
|
postmarketing
|
|
|
x
|
|
|
|
Mediastinal disorder
|
Mediastinal disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Plasma cell myeloma
|
Plasma cell myeloma
|
postmarketing
|
|
|
x
|
|
|
|
Plasmacytoma
|
Plasma cell myeloma
|
postmarketing
|
|
|
x
|
|
|
|
Fungal infection
|
Fungal infection
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Myelodysplastic syndrome
|
Myelodysplastic syndrome
|
postmarketing
|
|
|
x
|
|
|
|
Myocardial infarction
|
Myocardial infarction
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Acute coronary syndrome
|
Myocardial infarction
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Neoplasm
|
Neoplasm
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Nervous system disorder
|
Nervous system disorder
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Opportunistic infection
|
Opportunistic infection
|
postmarketing
|
|
|
x
|
|
|
|
Pancreatitis
|
Pancreatitis
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Pancreatitis due to biliary obstruction
|
|
|
|
|
|
x
|
x
|
Peptic ulcer haemorrhage
|
Peptic ulcer haemorrhage
|
postmarketing
|
|
|
x
|
x
|
|
|
Polyp
|
Polyp
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Rhabdomyolysis
|
Rhabdomyolysis
|
postmarketing
|
|
|
x
|
|
|
|
Erythema multiforme
|
Stevens-Johnson syndrome
|
postmarketing
|
|
|
x
|
x
|
|
|
Stevens-Johnson syndrome
|
Stevens-Johnson syndrome
|
postmarketing
|
|
|
x
|
x
|
|
|
Thyroid disorder
|
Thyroid disorder
|
postmarketing
|
|
|
x
|
|
|
|
Toothache
|
Toothache
|
postmarketing
|
|
|
x
|
|
|
|
Tumour lysis syndrome
|
Tumour lysis syndrome
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Urinary incontinence
|
Urinary incontinence
|
postmarketing
|
|
|
x
|
|
|
|
Urethral disorder
|
Urinary tract disorder
|
postmarketing, 6.76%
|
|
|
x
|
x
|
x
|
x
|
Urinary tract disorder
|
Urinary tract disorder
|
postmarketing, 6.76%
|
|
|
x
|
x
|
x
|
x
|
Angiopathy
|
Angiopathy
|
postmarketing, 6.08%
|
|
|
x
|
x
|
x
|
x
|
Urinary retention
|
Urinary retention
|
postmarketing
|
|
|
x
|
|
|
|
Hepatic failure
|
Hepatic failure
|
postmarketing
|
|
|
x
|
|
x
|
x
|
Affect lability
|
Mood swings
|
postmarketing
|
|
|
x
|
|
|
x
|
Hepatitis cholestatic
|
Hepatitis cholestatic
|
postmarketing
|
|
|
x
|
|
|
x
|
Ventricular extrasystoles
|
Ventricular extrasystoles
|
postmarketing
|
|
|
x
|
|
|
|
Haemorrhage intracranial
|
Haemorrhage intracranial
|
postmarketing
|
|
|
x
|
x
|
|
|
Liver function test abnormal
|
Liver function test abnormal
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
Skin discolouration
|
Skin discolouration
|
postmarketing
|
|
|
x
|
|
|
|
Joint swelling
|
Joint swelling
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
|
|
Malnutrition
|
Malnutrition
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Acute hepatic failure
|
Acute hepatic failure
|
postmarketing
|
|
|
x
|
|
|
|
Photosensitivity reaction
|
Photosensitivity reaction
|
postmarketing
|
|
|
x
|
|
|
|
Skin hyperpigmentation
|
Skin hyperpigmentation
|
postmarketing
|
|
|
x
|
|
|
x
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Interstitial lung disease
|
Interstitial pneumonia
|
postmarketing
|
|
|
x
|
|
|
|
Interstitial lung disease
|
|
|
|
|
|
x
|
x
|
Myalgia
|
Myalgia
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
Teratogenicity
|
Teratogenicity
|
postmarketing
|
|
|
x
|
|
|
|
Discomfort
|
Discomfort
|
postmarketing
|
|
x
|
x
|
x
|
|
|
Malaise
|
|
|
x
|
|
|
|
x
|
Visual acuity reduced
|
Visual acuity reduced
|
postmarketing
|
|
|
x
|
|
|
|
Neuritis
|
Peripheral motor neuropathy
|
postmarketing
|
|
|
x
|
x
|
|
|
Peripheral motor neuropathy
|
Peripheral motor neuropathy
|
postmarketing
|
|
|
x
|
x
|
|
|
Peripheral ischaemia
|
Peripheral ischaemia
|
postmarketing
|
|
|
x
|
|
|
|
Erectile dysfunction
|
Erectile dysfunction
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Sepsis
|
Sepsis
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
Haemorrhoidal haemorrhage
|
Haemorrhoidal haemorrhage
|
postmarketing
|
|
|
x
|
|
|
|
Caecitis
|
Caecitis
|
postmarketing
|
|
|
x
|
|
|
|
Rectal haemorrhage
|
Rectal haemorrhage
|
postmarketing, uncommon
|
|
|
x
|
x
|
x
|
x
|
Hepatobiliary disease
|
Hepatobiliary disease
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Iron overload
|
Iron overload
|
postmarketing
|
|
|
x
|
|
|
|
Intracranial venous sinus thrombosis
|
Intracranial venous sinus thrombosis
|
postmarketing
|
|
|
x
|
|
|
|
Fanconi syndrome acquired
|
Fanconi syndrome acquired
|
postmarketing
|
|
|
x
|
x
|
|
|
Bradycardia
|
Bradycardia
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
Blindness
|
Blindness
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Hypercoagulation
|
Hypercoagulation
|
postmarketing
|
|
|
x
|
|
|
|
Infestation
|
Infestation NOS
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
Tumour flare
|
Tumour flare
|
postmarketing, 0% - 9.7%
|
|
|
|
x
|
|
x
|
Embolism
|
Thromboembolic event
|
postmarketing
|
|
|
x
|
x
|
|
|
Cerebral ischaemia
|
Cerebral ischaemia
|
postmarketing
|
|
|
x
|
|
|
x
|
Hepatitis
|
Cytolytic hepatitis
|
postmarketing
|
|
|
x
|
|
|
x
|
Hearing impaired
|
Hearing impaired
|
postmarketing
|
|
|
x
|
x
|
|
|
Renal tubular necrosis
|
Renal tubular necrosis
|
postmarketing
|
|
|
x
|
|
|
|
Embolism venous
|
Venous thromboembolism
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Leukocytoclastic vasculitis
|
Leukocytoclastic vasculitis
|
postmarketing
|
|
|
x
|
|
|
|
Loss of libido
|
Loss of libido
|
postmarketing
|
|
|
x
|
x
|
|
x
|
Abscess
|
Abscess
|
|
|
x
|
|
|
|
|
Alveolitis allergic
|
Alveolitis allergic
|
|
|
x
|
|
|
|
|
Refractory cytopenia with unilineage dysplasia
|
Refractory anemia
|
|
|
|
|
|
x
|
x
|
Angina pectoris
|
Angina pectoris
|
|
|
x
|
|
|
x
|
x
|
Aortic disorder
|
Aortic disorder
|
|
|
|
|
|
x
|
x
|
Aphasia
|
Aphasia
|
|
|
|
|
|
x
|
x
|
Arthritis
|
Arthritis
|
|
|
x
|
|
|
x
|
x
|
Arthritis aggravated
|
|
|
x
|
|
|
x
|
x
|
Gouty arthritis
|
Gouty arthritis
|
|
|
|
|
|
x
|
x
|
Gout
|
Gouty arthritis
|
|
|
|
|
|
x
|
x
|
Gout
|
|
|
x
|
|
|
x
|
x
|
Asthma
|
Asthma
|
|
|
x
|
|
|
|
|
Bronchioloalveolar carcinoma
|
Bronchioloalveolar carcinoma
|
|
|
|
|
|
x
|
x
|
Cerebral infarction
|
Cerebral infarction
|
|
|
|
|
|
x
|
x
|
Neck pain
|
Neck pain
|
|
|
|
|
|
x
|
x
|
Cholecystitis
|
Cholecystitis
|
|
|
|
|
|
x
|
x
|
Large intestine polyp
|
Colonic polyp
|
|
|
x
|
|
|
x
|
x
|
Confusional state
|
Confusional state
|
|
|
|
|
|
x
|
x
|
Feeling abnormal
|
Confusional state
|
|
|
|
|
|
x
|
x
|
Malaise
|
|
|
x
|
|
|
|
x
|
Cystitis
|
Cystitis
|
|
|
x
|
|
|
|
|
Bladder pain
|
Cystitis
|
|
|
x
|
|
|
|
|
Cystitis noninfective
|
Cystitis
|
|
|
x
|
|
|
|
|
Sudden death
|
Sudden death
|
|
|
|
|
|
x
|
x
|
Decubitus ulcer
|
Decubitus ulcer
|
|
|
x
|
|
|
|
|
Dermatitis atopic
|
Dermatitis atopic
|
|
|
x
|
|
|
|
|
Diabetes mellitus
|
Diabetes mellitus
|
|
|
x
|
|
|
|
|
Diplopia
|
Diplopia
|
|
|
x
|
|
|
|
|
Diverticulitis
|
Diverticulitis
|
|
|
x
|
|
|
x
|
x
|
Diverticulum
|
Diverticulum
|
|
|
x
|
|
|
|
|
Dysarthria
|
Dysarthria
|
|
|
|
|
|
x
|
x
|
Osteoarthritis
|
Dysarthria
|
|
|
|
|
|
x
|
x
|
Ear pain
|
Ear pain
|
|
|
x
|
|
|
|
|
Femur fracture
|
Femur fracture
|
|
|
|
|
|
x
|
x
|
Femoral neck fracture
|
Femoral neck fracture
|
|
|
|
|
|
x
|
x
|
Flushing
|
Flushing
|
|
|
x
|
|
|
|
|
Localised infection
|
Localised infection
|
|
|
|
|
|
x
|
x
|
Gastritis
|
Gastritis
|
|
|
x
|
|
|
x
|
x
|
Gastrooesophageal reflux disease
|
Gastrooesophageal reflux disease
|
|
|
x
|
|
|
x
|
x
|
Glossodynia
|
Glossodynia
|
|
|
|
|
|
|
x
|
Basedow's disease
|
Basedow's disease
|
|
|
|
|
|
x
|
x
|
Hallucination
|
Hallucination
|
|
|
|
|
|
|
x
|
Cardiac arrest
|
Cardiac arrest
|
|
|
|
|
|
x
|
x
|
Haemochromatosis
|
Haemochromatosis
|
|
|
x
|
|
|
|
|
Haemorrhage
|
Haemorrhage
|
|
|
x
|
|
|
|
|
Haemoglobin
|
Haemorrhage
|
|
|
x
|
|
|
|
|
Haemorrhoids
|
Haemorrhoids
|
|
|
x
|
|
|
|
|
Inguinal hernia
|
Inguinal hernia
|
|
|
|
|
|
x
|
x
|
Herpes simplex
|
Herpes simplex
|
|
|
x
|
|
|
|
|
Herpes virus infection
|
Herpes virus infection
|
|
|
|
|
|
x
|
x
|
Hip fracture
|
Hip fracture
|
|
|
|
|
|
x
|
x
|
Hirsutism
|
Hirsutism
|
|
|
|
|
|
|
x
|
Hyperbilirubinaemia
|
Hyperbilirubinaemia
|
|
|
x
|
|
|
x
|
x
|
Hypercholesterolaemia
|
Hypercholesterolaemia
|
|
|
x
|
|
|
|
|
Hypernatraemia
|
Hypernatraemia
|
|
|
|
|
|
x
|
x
|
Hypoglycaemia
|
Hypoglycaemia
|
|
|
|
|
|
x
|
x
|
Incontinence
|
Incontinence
|
|
|
x
|
|
|
|
|
Kidney infection
|
Kidney infection
|
|
|
|
|
|
x
|
x
|
Inflammation
|
Inflammation
|
|
|
x
|
|
|
|
|
Influenza
|
Influenza
|
|
|
x
|
|
|
x
|
x
|
Intestinal perforation
|
Intestinal perforation
|
|
|
|
|
|
x
|
x
|
Irritable bowel syndrome
|
Irritable bowel syndrome
|
|
|
x
|
|
|
x
|
x
|
Functional gastrointestinal disorder
|
Irritable bowel syndrome
|
|
|
x
|
|
|
x
|
x
|
Renal failure acute
|
Renal failure acute
|
|
|
|
|
|
x
|
x
|
Chronic obstructive pulmonary disease
|
Chronic obstructive pulmonary disease
|
|
|
x
|
|
|
|
x
|
COPD exacerbation
|
|
|
|
|
|
x
|
x
|
Bronchial hyperreactivity
|
Chronic obstructive pulmonary disease
|
|
|
x
|
|
|
|
x
|
Lymphoma
|
Lymphoma
|
|
|
|
|
|
x
|
x
|
Non-Hodgkin's lymphoma
|
Lymphoma
|
|
|
|
|
|
x
|
x
|
Macular degeneration
|
Macular degeneration
|
|
|
x
|
|
|
|
|
Melaena
|
Melaena
|
|
|
|
|
|
x
|
x
|
Metrorrhagia
|
Metrorrhagia
|
|
|
x
|
|
|
|
|
Multi-organ failure
|
Multi-organ failure
|
|
|
x
|
|
|
x
|
x
|
Nodule
|
Nodule
|
|
|
|
|
|
x
|
x
|
Ocular hypertension
|
Ocular hypertension
|
|
|
|
|
|
|
x
|
Osteopenia
|
Osteopenia
|
|
|
x
|
|
|
|
|
Pelvic pain
|
Pelvic pain
|
|
|
|
|
|
x
|
x
|
Periarthritis
|
Periarthritis
|
|
|
x
|
|
|
|
|
Pseudomonas infection
|
Pseudomonas infection
|
|
|
|
|
|
x
|
x
|
Psychosomatic disease
|
Psychosomatic disease
|
|
|
x
|
|
|
|
|
Pulmonary oedema
|
Pulmonary oedema
|
|
|
x
|
|
|
x
|
x
|
Rales
|
Rales
|
|
|
x
|
|
|
|
|
Rib fracture
|
Rib fracture
|
|
|
x
|
|
|
x
|
x
|
Sciatica
|
Sciatica
|
|
|
x
|
|
|
|
|
Cardiogenic shock
|
Cardiogenic shock
|
|
|
|
|
|
x
|
x
|
Septic shock
|
Septic shock
|
|
|
|
|
|
x
|
x
|
Spinal cord compression
|
Spinal cord compression
|
|
|
|
|
|
x
|
x
|
Splenic infarction
|
Splenic infarction
|
|
|
|
|
|
x
|
x
|
Splenomegaly
|
Splenomegaly
|
|
|
x
|
|
|
|
|
Staphylococcal infection
|
Staphylococcal infection
|
|
|
|
|
|
x
|
x
|
Aphthous stomatitis
|
Aphthous stomatitis
|
|
|
x
|
|
|
|
|
Subarachnoid haemorrhage
|
Subarachnoid haemorrhage
|
|
|
|
|
|
x
|
x
|
Supraventricular tachycardia
|
Supraventricular tachycardia
|
|
|
|
|
|
|
x
|
Thrombophlebitis
|
Thrombophlebitis
|
|
|
x
|
|
|
|
|
Thrombosis
|
Thrombosis
|
|
|
|
|
|
x
|
x
|
Upper gastrointestinal haemorrhage
|
Upper gastrointestinal haemorrhage
|
|
|
|
|
|
x
|
x
|
Presyncope
|
Syncope vasovagal
|
|
|
x
|
|
|
|
|
Vertigo
|
Vertigo
|
|
|
x
|
|
|
x
|
x
|
Viraemia
|
Viraemia
|
|
|
|
|
x
|
|
|
Weight increased
|
Weight increased
|
|
|
x
|
|
|
|
|
Wheezing
|
Wheezing
|
|
|
|
|
|
x
|
x
|
Laceration
|
Laceration
|
|
|
x
|
|
|
|
|
Tachyarrhythmia
|
Tachyarrhythmia
|
|
|
|
|
|
x
|
x
|
Fungaemia
|
Fungaemia
|
|
|
|
|
x
|
|
|
Rash pustular
|
Rash pustular
|
|
|
x
|
|
|
|
|
Acute sinusitis
|
Acute sinusitis
|
|
|
|
|
|
x
|
x
|
Cholecystitis acute
|
Cholecystitis acute
|
|
|
|
|
|
x
|
x
|
Pelvic fracture
|
Pelvic fracture
|
|
|
|
|
|
x
|
x
|
Urosepsis
|
Urosepsis
|
|
|
|
|
|
x
|
x
|
Migraine
|
Migraine
|
|
|
|
|
|
x
|
x
|
Impaired healing
|
Impaired healing
|
|
|
x
|
|
|
|
|
Myocardial ischaemia
|
Myocardial ischaemia
|
|
|
|
|
|
x
|
x
|
Sinus congestion
|
Sinus congestion
|
|
|
x
|
|
|
|
|
Lung cancer metastatic
|
Lung cancer metastatic
|
|
|
|
|
|
x
|
x
|
Haemoglobin decreased
|
Haemoglobin decreased
|
|
|
|
|
|
x
|
x
|
Road traffic accident
|
Road traffic accident
|
|
|
|
|
|
x
|
x
|
Malaise
|
Malaise
|
|
|
x
|
|
|
|
x
|
Ill-defined disorder
|
Malaise
|
|
|
x
|
|
|
|
x
|
Abdominal pain upper
|
Abdominal pain upper
|
|
|
|
|
|
x
|
x
|
Abdominal tenderness
|
Abdominal tenderness
|
|
|
x
|
|
|
|
|
Small intestinal obstruction
|
Small intestinal obstruction
|
|
|
|
|
|
x
|
x
|
Hepatotoxicity
|
Hepatotoxicity
|
|
|
|
|
x
|
|
x
|
Cerebellar infarction
|
Cerebellar infarction
|
|
|
|
|
|
x
|
x
|
Clostridium difficile colitis
|
Clostridium difficile colitis
|
|
|
|
|
|
|
x
|
Productive cough
|
Productive cough
|
|
|
x
|
|
|
|
|
Frequent bowel movements
|
Frequent bowel movements
|
|
|
x
|
|
|
|
|
Furuncle
|
Furuncle
|
|
|
x
|
|
|
|
|
Azotaemia
|
Azotaemia
|
|
|
|
|
|
x
|
x
|
Disease progression
|
Disease progression
|
|
|
|
|
|
x
|
x
|
Ventricular dysfunction
|
Ventricular dysfunction
|
|
|
|
|
|
x
|
x
|
Cervical vertebral fracture
|
Cervical vertebral fracture
|
|
|
|
|
|
x
|
x
|
Spinal compression fracture
|
Spinal compression fracture
|
|
|
x
|
|
|
x
|
x
|
Renal mass
|
Renal mass
|
|
|
|
|
|
x
|
x
|
Warm type haemolytic anaemia
|
Warm type haemolytic anaemia
|
|
|
|
|
|
x
|
x
|
Transfusion reaction
|
Transfusion reaction
|
|
|
x
|
|
|
x
|
x
|
Peripheral coldness
|
Peripheral coldness
|
|
|
x
|
|
|
|
|
Mucosal inflammation
|
Mucosal inflammation
|
|
|
x
|
|
|
|
|
Musculoskeletal stiffness
|
Stiffness
|
|
|
x
|
|
|
|
|
Arrhythmia supraventricular
|
Arrhythmia supraventricular
|
|
|
|
|
|
x
|
x
|
Lymphadenopathy
|
Lymphadenopathy
|
|
|
x
|
|
|
|
|
Visual impairment
|
Visual disturbance
|
|
|
x
|
|
|
|
|
Altered state of consciousness
|
Depressed level of consciousness
|
|
|
|
|
|
x
|
x
|
Depressed level of consciousness
|
Depressed level of consciousness
|
|
|
|
|
|
x
|
x
|
Chondrocalcinosis
|
Chondrocalcinosis
|
|
|
|
|
|
x
|
x
|
Oral infection
|
Oral infection
|
|
|
|
|
|
x
|
x
|
Gait disturbance
|
Gait disturbance
|
|
|
|
|
|
x
|
x
|
Cardio-respiratory arrest
|
Cardio-respiratory arrest
|
|
|
|
|
|
x
|
x
|
Ear infection
|
Ear infection
|
|
|
|
|
|
x
|
x
|
Dyssomnia
|
Dyssomnia
|
|
|
x
|
|
|
|
|
Enterobacter sepsis
|
Enterobacter sepsis
|
|
|
|
|
|
x
|
x
|
Limb injury
|
Limb injury
|
|
|
x
|
|
|
|
|
Culture negative
|
Culture negative
|
|
|
|
|
|
x
|
|
Mental status changes
|
Mental status changes
|
|
|
x
|
|
|
|
|
Cardiomyopathy
|
Cardiomyopathy
|
|
|
|
|
|
x
|
x
|
Prostate cancer metastatic
|
Prostate cancer metastatic
|
|
|
|
|
|
x
|
x
|
Device related infection
|
Central line infection
|
|
|
|
|
|
x
|
x
|
Dental discomfort
|
Dental discomfort
|
|
|
x
|
|
|
|
|
Troponin I increased
|
Troponin I increased
|
|
|
|
|
|
x
|
x
|
Neutrophilic dermatosis
|
Neutrophilic dermatosis
|
|
|
x
|
|
|
|
|
Respiratory failure
|
Respiratory failure
|
|
|
|
|
|
x
|
x
|
Rhinorrhoea
|
Rhinorrhoea
|
|
|
x
|
|
|
|
|
Excoriation
|
Abrasion NOS
|
|
|
x
|
|
|
|
|
Calculus ureteric
|
Calculus ureteric
|
|
|
|
|
|
x
|
x
|
Thrombophlebitis superficial
|
Thrombophlebitis superficial
|
|
|
|
|
|
x
|
x
|
Glioblastoma multiforme
|
Glioblastoma multiforme
|
|
|
|
|
x
|
|
|
Ageusia
|
Ageusia
|
|
|
x
|
|
|
|
|
Gastrointestinal tract irritation
|
Gastrointestinal tract irritation
|
|
|
x
|
|
|
|
|
Somnolence
|
Somnolence
|
|
|
x
|
|
|
|
|