| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 
| Neutropenia | Neutropenia | postmarketing — 33.4% - 79% | 3.43% - 17.9% | x | x | x | x | x | 
| Diarrhoea | Diarrhoea | postmarketing — 1.7% - 60.1% | 0.571% - 27.4% | x | x | x | x | x | 
| Loose stools | common |  | x |  | x | x | x | 
| Muscle spasms | Cramp muscle | very common, 15.2% - 33.4% | 6% - 21.1% | x | x | x | x | x | 
| Muscle spasms | postmarketing, 0.746% - 16.7% |  | x | x | x |  | x | 
| Thrombocytopenia | Thrombocytopenia | postmarketing — 12.2% - 74% | 3% - 10.6% | x | x | x | x | x | 
| Tremor | Tremor | postmarketing, 21.2% | 7.4% - 7.43% | x | x | x |  | x | 
| Constipation | Constipation | postmarketing — 0.746% - 40.5% | 0.286% - 21.1% | x | x | x | x | x | 
| Nausea | Nausea | postmarketing — 0.746% - 29.9% | 0.571% - 21.4% | x | x | x | x | x | 
| Asthenia | Fatigue | postmarketing — 4.7% - 43.9% | 4.86% - 41.7% | x | x | x | x | x | 
| Asthenia | common, 2.99% - 14.2% |  | x |  | x | x | x | 
| Fatigue | Fatigue | postmarketing — 4.7% - 43.9% | 4.86% - 41.7% | x | x | x | x | x | 
| Vision blurred | Vision blurred | postmarketing, 17.3% | 11.4% | x | x | x |  | x | 
| Pruritus | Pruritus | postmarketing — 0.746% - 44.6% | 4.5% - 5.14% | x | x | x | x | x | 
| Decreased appetite | Anorexia | common, 15.6% | 9.7% - 9.71% | x |  | x | x | x | 
| Decreased appetite | postmarketing, 0.746% - 14.2% | 4% |  | x | x |  | x | 
| Dermatitis | Rash | postmarketing — 1.49% - 37.8% | 1.5% - 9.43% |  | x | x | x | x | 
| Rash | Rash | postmarketing — 1.49% - 37.8% | 1.5% - 9.43% |  | x | x | x | x | 
| Oedema peripheral | Oedema peripheral | postmarketing — 0% - 26.3% | 7.5% - 21.1% | x | x | x | x | x | 
| Body temperature increased | Body temperature increased | postmarketing — 2.24% - 27.5% | 6% - 23.4% | x | x | x | x | x | 
| Intermittent fever |  |  |  |  |  | x | x | 
| Nasopharyngitis | Nasopharyngitis | postmarketing — 11.6% - 23.5% | 7.5% - 17.1% | x | x | x | x | x | 
| Rhinorrhoea |  |  | x |  |  |  |  | 
| Upper respiratory tract infection | Upper respiratory tract infection | postmarketing, 0% - 24.6% | 15.7% |  | x | x | x | x | 
| Pain in extremity | Pain in extremity | common, 11.9% | 9.1% - 9.14% |  |  | x | x | x | 
| Foot pain | common |  |  |  | x |  |  | 
| Bronchitis | Bronchitis | postmarketing — 11.3% - 11.6% | 4.5% - 8.6% | x | x | x | x | x | 
| Hypoaesthesia | Hypoaesthesia | common, 10.2% | 7.1% - 7.14% |  |  | x |  | x | 
| Dysgeusia | Dysgeusia | postmarketing — 15.3% | 9.7% - 9.71% | x | x | x | x | x | 
| Dizziness | Dizziness | postmarketing — 1.98% - 23.2% | 0.857% - 16.9% | x | x | x | x | x | 
| Syncope | postmarketing, 2.83% | 0.857% | x | x | x | x | x | 
| Anaemia | Anaemia | postmarketing — 6.1% - 31.4% | 5.71% - 23.7% | x | x | x | x | x | 
| Abdominal pain | Abdominal pain | postmarketing — 3.73% - 10.9% | 6% - 6.29% |  | x | x | x | x | 
| Gastrointestinal pain | Abdominal pain | postmarketing — 3.73% - 10.9% | 6% - 6.29% |  | x | x | x | x | 
| Bowel spasm | uncommon |  | x |  | x |  |  | 
| Dry skin | Dry skin | postmarketing — 9.35% - 10.1% | 1.5% - 4% | x | x | x | x | x | 
| Respiratory tract infection | Respiratory tract infection | common, 13.8% | 3% |  |  | x | x | x | 
| Pharyngitis | Pharyngitis | postmarketing — 13.6% | 9.4% - 9.43% | x | x | x | x | x | 
| Cough | Cough | postmarketing — 0.746% - 28.4% | 6% | x | x | x | x | x | 
| Vomiting | Vomiting | postmarketing — 0.746% - 12.2% | 9.4% - 9.43% | x | x | x | x | x | 
| Leukopenia | Leukopenia | very common, 3.97% - 14.9% | 0.286% - 3% | x |  | x | x | x | 
| Pneumonia | Pneumonia | postmarketing — 7.4% - 14.2% | 5.43% - 8.3% | x | x | x | x | x | 
| Hyperhidrosis | Sweating increased | common, 9.92% | 7.14% |  |  | x | x | x | 
| Hyperhidrosis | postmarketing |  |  | x | x |  |  | 
| Sweating |  |  | x |  |  |  |  | 
| Headache | Headache | postmarketing — 14.5% | 7.5% | x | x | x | x | x | 
| Dyspnoea | Dyspnoea | postmarketing — 4.7% - 23.5% | 8.9% - 17.1% | x | x | x | x | x | 
| Dyspnoea exacerbated |  |  |  |  |  | x | x | 
| Back pain | Back pain | postmarketing — 1.49% - 25.8% | 18.6% |  | x | x | x | x | 
| Dysuria | Dysuria | common, 6.76% |  | x |  | x | x | x | 
| Hypothyroidism | Primary hypothyroidism | common, 6.76% |  |  |  | x | x | x | 
| Hypothyroidism | postmarketing |  | x | x | x |  | x | 
| Primary hypothyroidism | Primary hypothyroidism | common, 6.76% |  |  |  | x | x | x | 
| Abdominal distension | Abdominal distension | common |  | x |  | x |  |  | 
| Agranulocytosis | Agranulocytosis | common |  | x |  | x | x | x | 
| Alopecia | Alopecia | common |  | x |  | x |  |  | 
| Anxiety | Anxiety | common |  | x |  | x |  |  | 
| Conjunctivitis | Conjunctivitis | common |  | x |  | x |  |  | 
| Flatulence | Flatulence | common |  | x |  | x |  |  | 
| Hordeolum | Hordeolum | common |  | x |  | x |  |  | 
| Pulmonary hypertension | Pulmonary hypertension | common |  | x |  | x | x | x | 
| Eye pruritus | Eye pruritus | common |  |  |  | x |  |  | 
| Nasal congestion | Nasal congestion | common |  | x |  | x |  |  | 
| Night sweats | Night sweats | common |  | x |  | x | x | x | 
| Paraesthesia | Paraesthesia | common |  | x |  | x |  |  | 
| Petechiae | Petechiae | common |  | x |  | x |  |  | 
| Polycythaemia | Polycythaemia | common |  | x |  | x |  |  | 
| Prurigo | Prurigo | common |  |  |  | x |  |  | 
| Skin lesion | Skin lesion | common |  |  |  | x |  |  | 
| Erythema | Erythema | common |  | x |  | x | x | x | 
| Weight decreased | Weight decreased | postmarketing — 0% - 19.5% | 14.9% | x | x | x |  | x | 
| Dry mouth | Dry mouth | postmarketing — 7.08% | 3.71% | x | x | x | x | x | 
| Stomatitis | Mouth ulceration | common |  | x |  | x |  |  | 
| Stomatitis | postmarketing |  | x | x | x |  |  | 
| Mouth ulceration | Mouth ulceration | common |  | x |  | x |  |  | 
| Peripheral sensory neuropathy | Peripheral sensory neuropathy | common |  |  |  | x |  |  | 
| Hypomagnesaemia | Hypomagnesaemia | postmarketing — 6.8% | 2.86% | x | x | x | x | x | 
| Aspartate aminotransferase increased | Aspartate aminotransferase increased | common |  |  |  | x |  |  | 
| Alanine aminotransferase increased | Alanine aminotransferase increased | common, 8.11% |  |  |  | x | x | x | 
| Polyneuropathy | Polyneuropathy | common |  | x |  | x |  |  | 
| Rash macular | Rash macular | common |  |  |  | x |  |  | 
| Dyspnoea exertional | Dyspnoea exertional | common |  | x |  | x | x | x | 
| Abdominal discomfort | Abdominal discomfort | common |  |  |  | x |  |  | 
| Upset stomach | uncommon |  |  |  | x |  |  | 
| Gastrointestinal tract irritation |  |  | x |  |  |  |  | 
| Rash erythematous | Rash erythematous | common |  |  |  | x |  |  | 
| Blood creatinine increased | Blood creatinine increased | common |  |  |  | x | x | x | 
| Dry eye | Dry eye | common |  | x |  | x |  |  | 
| Local swelling | Peripheral swelling | common |  |  |  | x | x | x | 
| Insomnia | Insomnia | common |  | x |  | x | x | x | 
| Mood swings | Mood alteration NOS | common |  | x |  | x |  |  | 
| Mood swings | postmarketing |  |  | x |  |  | x | 
| Hypokalaemia | Hypokalaemia | postmarketing — 2.24% - 13.6% | 1.43% - 6% | x | x | x | x | x | 
| Oropharyngeal pain | Oropharyngeal pain | 0% - 9.7% |  |  |  |  |  | x | 
| Dehydration | Dehydration | postmarketing, 2.99% - 7.46% | 4.29% | x | x | x | x | x | 
| Deep vein thrombosis | Deep vein thrombosis | postmarketing — 3.73% - 9.35% | 3.14% - 4.29% | x | x | x | x | x | 
| Lymphopenia | Lymphopenia | 2.83% - 7.46% | 1.14% - 1.43% |  |  |  |  | x | 
| Neuropathy peripheral | Neuropathy | uncommon, 6.52% | 3.71% | x |  | x |  | x | 
| Neuropathy peripheral | postmarketing, common |  | x | x | x | x | x | 
| Endocrine disorder | Endocrine disorder | postmarketing, 6.76% |  |  | x | x | x | x | 
| Hypertension | Hypertension | postmarketing — 6.08% - 7.93% | 5.71% | x | x | x | x | x | 
| Arthralgia | Arthralgia | postmarketing — 1.49% - 8.21% |  | x | x | x | x | x | 
| Musculoskeletal discomfort | Arthralgia | postmarketing — 1.49% - 8.21% |  | x | x | x | x | x | 
| Myalgia | postmarketing, common |  | x | x | x | x | x | 
| Febrile neutropenia | Febrile neutropenia | postmarketing — 1.7% - 6% | 0% | x | x | x | x | x | 
| Bone pain | Bone pain | postmarketing — 1.13% - 13.6% | 0% - 11.1% |  | x | x |  | x | 
| Hypotension | Hypotension | postmarketing — 2.99% - 7.08% | 4.29% | x | x | x | x | x | 
| Squamous cell carcinoma of skin | Squamous cell carcinoma of skin | 2.99% |  |  |  |  |  | x | 
| Palpitations | Palpitations | uncommon, 5.41% |  | x |  | x | x | x | 
| Depression | Depression | postmarketing — 2.83% | 1.71% |  | x | x |  | x | 
| Cardiac disorder | Cardiac disorder | postmarketing, 5.41% |  |  | x | x | x | x | 
| Infection | Infection | postmarketing, common |  | x | x | x | x | x | 
| Oedema | Oedema | postmarketing, common |  | x | x | x | x | x | 
| Pitting edema |  |  | x |  |  |  |  | 
| Pancytopenia | Pancytopenia | postmarketing, common |  | x | x | x | x | x | 
| Myelosuppression | uncommon |  | x |  | x |  |  | 
| Bone marrow depression |  |  |  |  |  | x | x | 
| Tinnitus | Tinnitus | postmarketing, common |  | x | x | x |  |  | 
| Urticaria | Urticaria | postmarketing, common |  | x | x | x |  |  | 
| Chills | Rigors | postmarketing, common |  | x | x | x | x | x | 
| Chills |  |  |  |  |  |  | x | 
| Hyponatraemia | Hyponatraemia | common, 2.24% |  | x |  | x |  | x | 
| Pulmonary embolism | Pulmonary embolism | postmarketing — 1.49% - 3.97% | 0.857% | x | x | x | x | x | 
| Hypocalcaemia | Hypocalcaemia | postmarketing, 1.49% - 8.78% | 1.71% - 2.86% | x | x | x |  | x | 
| Hypoxia | Hypoxia | 1.49% - 2.24% |  |  |  |  | x | x | 
| General physical health deterioration | General physical health deterioration | 1.49% - 2.24% |  |  |  |  |  | x | 
| Atrial fibrillation | Atrial fibrillation | postmarketing, 3.12% - 3.68% | 0.571% - 1.14% | x | x | x | x | x | 
| Fibrillation atrial aggravated |  |  |  |  |  | x | x | 
| Bacteraemia | Bacteraemia | 1.49% |  | x |  | x | x | x | 
| Cellulitis | Cellulitis | uncommon, 1.49% - 2.24% |  | x |  | x | x | x | 
| Pleural effusion | Pleural effusion | uncommon, 1.49% - 7.46% |  | x |  | x | x | x | 
| Renal failure | Renal failure | postmarketing, 1.49% - 3.73% |  |  | x | x | x | x | 
| Urinary tract infection | Urinary tract infection | uncommon, 1.42% - 8.5% | 0.286% - 5.43% |  |  | x | x | x | 
| Muscular weakness | Muscular weakness | postmarketing — 1.49% - 5.97% | 2.86% |  | x | x |  | x | 
| Staphylococcal bacteraemia | Staphylococcal bacteraemia | 1.49% |  |  |  |  |  | x | 
| Respiratory distress | Respiratory distress | postmarketing — 1.13% - 1.49% | 0% | x | x | x | x | x | 
| Shock | Syncope | postmarketing, 2.83% | 0.857% | x | x | x | x | x | 
| Syncope | Syncope | postmarketing, 2.83% | 0.857% | x | x | x | x | x | 
| Syncope vasovagal |  |  | x |  |  |  |  | 
| Loss of consciousness | Syncope | postmarketing, 2.83% | 0.857% | x | x | x | x | x | 
| Cataract | Cataract unilateral | 1.42% | 0% |  |  | x |  | x | 
| Cataract | postmarketing, 1.7% | 0.286% |  | x | x |  | x | 
| Hypophosphataemia | Hypophosphataemia | postmarketing, 2.55% | 0% |  | x | x |  | x | 
| Cardiac failure congestive | Cardiac failure congestive | postmarketing — 1.42% | 0% - 0.286% | x | x | x | x | x | 
| Amenorrhoea | Amenorrhoea | uncommon |  |  |  | x |  |  | 
| Aortic valve stenosis | Aortic valve stenosis | uncommon |  |  |  | x |  |  | 
| Candida infection | Oral candidiasis | uncommon |  | x |  | x |  |  | 
| Oral candidiasis | Oral candidiasis | uncommon |  | x |  | x |  |  | 
| Chest pain | Chest pain | postmarketing — 8.22% | 5.71% |  | x | x | x | x | 
| Clostridial infection | Clostridial infection | uncommon |  |  |  | x | x | x | 
| Drug eruption | Drug eruption | uncommon |  |  |  | x |  |  | 
| Dyspepsia | Dyspepsia | postmarketing — common |  | x | x | x |  |  | 
| Gastroenteritis | Gastroenteritis | uncommon |  | x |  | x | x | x | 
| Gynaecomastia | Gynaecomastia | uncommon |  |  |  | x |  |  | 
| Dysphonia | Hoarseness | uncommon |  | x |  | x |  | x | 
| Lethargy | Lethargy | postmarketing — 6.8% | 2.29% | x | x | x |  | x | 
| Hypotonia | Hypotonia | uncommon |  |  |  | x |  |  | 
| Muscle relaxant therapy | Hypotonia | uncommon |  |  |  | x |  |  | 
| Nervousness | Nervousness | uncommon |  |  |  | x |  |  | 
| Tension | Nervousness | uncommon |  |  |  | x |  |  | 
| Osteoporosis | Osteoporosis | uncommon |  | x |  | x |  |  | 
| Lobar pneumonia | Lobar pneumonia | uncommon |  |  |  | x | x | x | 
| Rhinitis | Rhinitis | uncommon |  | x |  | x | x | x | 
| Sinusitis | Sinusitis | postmarketing — 7.37% | 4.57% | x | x | x | x | x | 
| Speech disorder | Speech disorder | uncommon |  |  |  | x |  |  | 
| Cerebrovascular accident | Cerebrovascular accident | postmarketing — 1.98% | 0.857% |  | x | x | x | x | 
| Tachycardia | Tachycardia | postmarketing — 1.7% | 0.286% | x | x | x |  | x | 
| Varicose vein | Varicose vein | uncommon |  |  |  | x |  |  | 
| Acute febrile neutrophilic dermatosis | Acute febrile neutrophilic dermatosis | uncommon |  | x |  | x | x | x | 
| Pollakiuria | Micturition urgency | uncommon |  |  |  | x |  |  | 
| Micturition urgency | Micturition urgency | uncommon |  |  |  | x |  |  | 
| Burning sensation | Burning sensation | uncommon |  | x |  | x |  |  | 
| Agitation | Agitation | uncommon |  | x |  | x |  |  | 
| Swelling face | Swelling face | uncommon |  |  |  | x |  |  | 
| Injection site haemorrhage | Injection site haemorrhage | uncommon |  |  |  | x |  |  | 
| Injection site bruising | uncommon |  |  |  | x |  |  | 
| Sensory disturbance | Sensory disturbance | uncommon |  | x |  | x |  |  | 
| Skin irritation | Skin irritation | uncommon |  |  |  | x |  |  | 
| Eyelid oedema | Eyelid oedema | uncommon |  | x |  | x |  |  | 
| Joint stiffness | Joint stiffness | uncommon |  |  |  | x |  |  | 
| Colitis ischaemic | Colitis ischaemic | uncommon |  |  |  | x | x | x | 
| Skin fissures | Skin fissures | uncommon |  |  |  | x |  |  | 
| Areflexia | Areflexia | uncommon |  |  |  | x |  |  | 
| Abnormal dreams | Abnormal dreams | uncommon |  |  |  | x |  |  | 
| Dry throat | Dry throat | uncommon |  |  |  | x |  |  | 
| Eye irritation | Eye irritation | uncommon |  |  |  | x |  |  | 
| Lung infiltration | Lung infiltration | uncommon |  |  |  | x | x | x | 
| Perirectal abscess | Perirectal abscess | uncommon |  |  |  | x | x | x | 
| Blood bilirubin increased | Blood bilirubin increased | uncommon |  |  |  | x |  |  | 
| Aneurysm | Arterial aneurysm | uncommon |  | x |  | x |  |  | 
| Eye discharge | Eye discharge | uncommon |  |  |  | x |  |  | 
| Decreased interest | Decreased interest | uncommon |  |  |  | x |  |  | 
| Orbital oedema | Orbital oedema | uncommon |  |  |  | x |  |  | 
| Pruritus generalised | Pruritus generalised | uncommon |  |  |  | x |  |  | 
| Injection site bruising | Injection site bruising | uncommon |  |  |  | x |  |  | 
| Regurgitation | Regurgitation of food | uncommon |  |  |  | x |  |  | 
| Face oedema | Face oedema | uncommon |  |  |  | x |  |  | 
| Lip dry | Lip dry | uncommon |  |  |  | x |  |  | 
| Sensation of heaviness | Sensation of heaviness | uncommon |  |  |  | x |  |  | 
| Blood uric acid increased | Hyperuricaemia | uncommon |  |  |  | x |  |  | 
| Hyperuricaemia | Hyperuricaemia | uncommon |  |  |  | x |  |  | 
| Klebsiella sepsis | Klebsiella sepsis | uncommon |  | x |  | x | x | x | 
| Lip haemorrhage | Lip haemorrhage | uncommon |  |  |  | x |  |  | 
| Sleep disorder | Sleep disorder | uncommon |  | x |  | x |  |  | 
| Mucosal dryness | Mucosal dryness | uncommon |  |  |  | x |  |  | 
| Post procedural haemorrhage | Post procedural haemorrhage | uncommon |  |  |  | x | x | x | 
| Ear discomfort | Ear discomfort | uncommon |  | x |  | x |  |  | 
| Lymphoma cutis | Lymphoma cutis | uncommon |  |  |  | x |  |  | 
| Rhinitis allergic | Rhinitis allergic | uncommon |  | x |  | x |  |  | 
| Basal cell carcinoma | Basal cell carcinoma | postmarketing, uncommon |  |  | x | x |  | x | 
| Musculoskeletal pain | Musculoskeletal pain | postmarketing, uncommon |  |  | x | x |  |  | 
| Pain | Pain | postmarketing, uncommon |  | x | x | x | x | x | 
| Influenza like illness | Influenza like illness | postmarketing, uncommon |  | x | x | x |  |  | 
| Congenital anomaly | Congenital anomaly | postmarketing |  |  | x |  |  |  | 
| Developmental delay | Congenital anomaly | postmarketing |  |  | x |  |  |  | 
| Haemolytic anaemia | Haemolytic anaemia | postmarketing |  |  | x | x | x | x | 
| Autoimmune haemolytic anaemia | Autoimmune haemolytic anaemia | postmarketing |  |  | x | x |  | x | 
| Angioedema | Angioedema | postmarketing |  |  | x | x |  | x | 
| Arrhythmia | Arrhythmia | postmarketing |  | x | x |  |  |  | 
| Ataxia | Ataxia | postmarketing |  |  | x |  |  |  | 
| Atrial flutter | Atrial flutter | postmarketing |  |  | x |  |  |  | 
| Mental disorder | Mental disorder | postmarketing |  |  | x | x | x | x | 
| Coagulopathy | Coagulopathy | postmarketing |  |  | x |  | x | x | 
| Breast disorder | Breast disorder | postmarketing |  |  | x | x | x | x | 
| Neoplasm malignant | Neoplasm malignant | postmarketing |  | x | x |  | x | x | 
| Carcinoma |  |  | x |  |  |  |  | 
| Skin cancer | Skin cancer | postmarketing |  |  | x |  |  |  | 
| Transient ischaemic attack | Transient ischaemic attack | postmarketing |  | x | x |  | x | x | 
| Cholestasis | Cholestasis | postmarketing |  |  | x |  |  |  | 
| Colitis | Colitis | postmarketing |  |  | x |  |  |  | 
| Connective tissue disorder | Connective tissue disorder | postmarketing |  |  | x | x | x | x | 
| Contusion | Contusion | postmarketing, uncommon |  | x | x | x | x | x | 
| Cyst | Cyst | postmarketing |  |  | x | x |  | x | 
| Deafness | Deafness | postmarketing |  |  | x | x |  |  | 
| Hearing impaired | postmarketing |  |  | x | x |  |  | 
| Dysphagia | Dysphagia | postmarketing |  | x | x | x | x | x | 
| Ecchymosis | Ecchymosis | postmarketing, common |  | x | x | x | x | x | 
| Eczema | Eczema | postmarketing |  |  | x |  |  |  | 
| Toxic epidermal necrolysis | Toxic epidermal necrolysis | postmarketing |  |  | x | x |  |  | 
| Epistaxis | Epistaxis | postmarketing, common |  | x | x | x | x | x | 
| Eye disorder | Eye disorder | postmarketing |  |  | x | x |  | x | 
| Gastrointestinal disorder | Gastrointestinal disorder | postmarketing |  |  | x | x | x | x | 
| Gastrointestinal haemorrhage | Gastrointestinal haemorrhage | postmarketing |  |  | x | x | x | x | 
| Gingival bleeding | Gingival bleeding | postmarketing |  | x | x | x |  |  | 
| Cardiac failure | Cardiac failure | postmarketing |  | x | x |  | x | x | 
| Haematoma | Haematoma | postmarketing |  | x | x |  |  |  | 
| Haematuria | Haematuria | postmarketing |  |  | x | x | x | x | 
| Haemolysis | Haemolysis | postmarketing |  |  | x | x |  |  | 
| Haemorrhagic disorder | Haemorrhagic disorder | postmarketing |  |  | x |  |  |  | 
| Hepatitis toxic | Hepatitis toxic | postmarketing |  |  | x |  |  | x | 
| Hyperglycaemia | Hyperglycaemia | postmarketing |  |  | x |  |  |  | 
| Hypersensitivity | Hypersensitivity | postmarketing, uncommon |  | x | x | x | x | x | 
| Hyperthyroidism | Hyperthyroidism | postmarketing |  |  | x | x |  | x | 
| Immune system disorder | Immune system disorder | postmarketing |  |  | x | x | x | x | 
| Ischaemia | Ischaemia | postmarketing |  |  | x |  | x | x | 
| Acute myeloid leukaemia | Acute myeloid leukaemia | postmarketing |  |  | x |  | x | x | 
| AML progression | postmarketing |  |  | x |  |  |  | 
| Acute leukaemia | Acute myeloid leukaemia | postmarketing |  |  | x |  | x | x | 
| Acute leukaemia |  |  | x |  |  | x | x | 
| Liver disorder | Liver disorder | postmarketing |  |  | x |  |  |  | 
| Hepatocellular injury | Liver disorder | postmarketing |  |  | x |  |  |  | 
| Foetor hepaticus | Liver disorder | postmarketing |  |  | x |  |  |  | 
| Mediastinal disorder | Mediastinal disorder | postmarketing |  |  | x | x | x | x | 
| Plasma cell myeloma | Plasma cell myeloma | postmarketing |  |  | x |  |  |  | 
| Plasmacytoma | Plasma cell myeloma | postmarketing |  |  | x |  |  |  | 
| Fungal infection | Fungal infection | postmarketing |  |  | x |  | x | x | 
| Myelodysplastic syndrome | Myelodysplastic syndrome | postmarketing |  |  | x |  |  |  | 
| Myocardial infarction | Myocardial infarction | postmarketing |  |  | x |  | x | x | 
| Acute coronary syndrome | Myocardial infarction | postmarketing |  |  | x |  | x | x | 
| Neoplasm | Neoplasm | postmarketing |  |  | x | x | x | x | 
| Nervous system disorder | Nervous system disorder | postmarketing |  |  | x | x | x | x | 
| Opportunistic infection | Opportunistic infection | postmarketing |  |  | x |  |  |  | 
| Pancreatitis | Pancreatitis | postmarketing |  |  | x |  | x | x | 
| Pancreatitis due to biliary obstruction |  |  |  |  |  | x | x | 
| Peptic ulcer haemorrhage | Peptic ulcer haemorrhage | postmarketing |  |  | x | x |  |  | 
| Polyp | Polyp | postmarketing |  |  | x | x |  | x | 
| Rhabdomyolysis | Rhabdomyolysis | postmarketing |  |  | x |  |  |  | 
| Erythema multiforme | Stevens-Johnson syndrome | postmarketing |  |  | x | x |  |  | 
| Stevens-Johnson syndrome | Stevens-Johnson syndrome | postmarketing |  |  | x | x |  |  | 
| Thyroid disorder | Thyroid disorder | postmarketing |  |  | x |  |  |  | 
| Toothache | Toothache | postmarketing |  |  | x |  |  |  | 
| Tumour lysis syndrome | Tumour lysis syndrome | postmarketing |  |  | x | x |  | x | 
| Urinary incontinence | Urinary incontinence | postmarketing |  |  | x |  |  |  | 
| Urethral disorder | Urinary tract disorder | postmarketing, 6.76% |  |  | x | x | x | x | 
| Urinary tract disorder | Urinary tract disorder | postmarketing, 6.76% |  |  | x | x | x | x | 
| Angiopathy | Angiopathy | postmarketing, 6.08% |  |  | x | x | x | x | 
| Urinary retention | Urinary retention | postmarketing |  |  | x |  |  |  | 
| Hepatic failure | Hepatic failure | postmarketing |  |  | x |  | x | x | 
| Affect lability | Mood swings | postmarketing |  |  | x |  |  | x | 
| Hepatitis cholestatic | Hepatitis cholestatic | postmarketing |  |  | x |  |  | x | 
| Ventricular extrasystoles | Ventricular extrasystoles | postmarketing |  |  | x |  |  |  | 
| Haemorrhage intracranial | Haemorrhage intracranial | postmarketing |  |  | x | x |  |  | 
| Liver function test abnormal | Liver function test abnormal | postmarketing |  | x | x | x | x | x | 
| Skin discolouration | Skin discolouration | postmarketing |  |  | x |  |  |  | 
| Joint swelling | Joint swelling | postmarketing, uncommon |  | x | x | x |  |  | 
| Malnutrition | Malnutrition | postmarketing |  |  | x | x | x | x | 
| Acute hepatic failure | Acute hepatic failure | postmarketing |  |  | x |  |  |  | 
| Photosensitivity reaction | Photosensitivity reaction | postmarketing |  |  | x |  |  |  | 
| Skin hyperpigmentation | Skin hyperpigmentation | postmarketing |  |  | x |  |  | x | 
| Skin disorder | Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  | x | x | x | x | 
| Interstitial lung disease | Interstitial pneumonia | postmarketing |  |  | x |  |  |  | 
| Interstitial lung disease |  |  |  |  |  | x | x | 
| Myalgia | Myalgia | postmarketing, common |  | x | x | x | x | x | 
| Teratogenicity | Teratogenicity | postmarketing |  |  | x |  |  |  | 
| Discomfort | Discomfort | postmarketing |  | x | x | x |  |  | 
| Malaise |  |  | x |  |  |  | x | 
| Visual acuity reduced | Visual acuity reduced | postmarketing |  |  | x |  |  |  | 
| Neuritis | Peripheral motor neuropathy | postmarketing |  |  | x | x |  |  | 
| Peripheral motor neuropathy | Peripheral motor neuropathy | postmarketing |  |  | x | x |  |  | 
| Peripheral ischaemia | Peripheral ischaemia | postmarketing |  |  | x |  |  |  | 
| Erectile dysfunction | Erectile dysfunction | postmarketing |  |  | x | x |  | x | 
| Sepsis | Sepsis | postmarketing |  | x | x | x | x | x | 
| Haemorrhoidal haemorrhage | Haemorrhoidal haemorrhage | postmarketing |  |  | x |  |  |  | 
| Caecitis | Caecitis | postmarketing |  |  | x |  |  |  | 
| Rectal haemorrhage | Rectal haemorrhage | postmarketing, uncommon |  |  | x | x | x | x | 
| Hepatobiliary disease | Hepatobiliary disease | postmarketing |  |  | x | x | x | x | 
| Iron overload | Iron overload | postmarketing |  |  | x |  |  |  | 
| Intracranial venous sinus thrombosis | Intracranial venous sinus thrombosis | postmarketing |  |  | x |  |  |  | 
| Fanconi syndrome acquired | Fanconi syndrome acquired | postmarketing |  |  | x | x |  |  | 
| Bradycardia | Bradycardia | postmarketing |  | x | x | x | x | x | 
| Blindness | Blindness | postmarketing |  |  | x | x |  | x | 
| Hypercoagulation | Hypercoagulation | postmarketing |  |  | x |  |  |  | 
| Infestation | Infestation NOS | postmarketing |  |  | x | x | x | x | 
| Tumour flare | Tumour flare | postmarketing, 0% - 9.7% |  |  |  | x |  | x | 
| Embolism | Thromboembolic event | postmarketing |  |  | x | x |  |  | 
| Cerebral ischaemia | Cerebral ischaemia | postmarketing |  |  | x |  |  | x | 
| Hepatitis | Cytolytic hepatitis | postmarketing |  |  | x |  |  | x | 
| Hearing impaired | Hearing impaired | postmarketing |  |  | x | x |  |  | 
| Renal tubular necrosis | Renal tubular necrosis | postmarketing |  |  | x |  |  |  | 
| Embolism venous | Venous thromboembolism | postmarketing |  |  | x | x |  | x | 
| Leukocytoclastic vasculitis | Leukocytoclastic vasculitis | postmarketing |  |  | x |  |  |  | 
| Loss of libido | Loss of libido | postmarketing |  |  | x | x |  | x | 
| Abscess | Abscess |  |  | x |  |  |  |  | 
| Alveolitis allergic | Alveolitis allergic |  |  | x |  |  |  |  | 
| Refractory cytopenia with unilineage dysplasia | Refractory anemia |  |  |  |  |  | x | x | 
| Angina pectoris | Angina pectoris |  |  | x |  |  | x | x | 
| Aortic disorder | Aortic disorder |  |  |  |  |  | x | x | 
| Aphasia | Aphasia |  |  |  |  |  | x | x | 
| Arthritis | Arthritis |  |  | x |  |  | x | x | 
| Arthritis aggravated |  |  | x |  |  | x | x | 
| Gouty arthritis | Gouty arthritis |  |  |  |  |  | x | x | 
| Gout | Gouty arthritis |  |  |  |  |  | x | x | 
| Gout |  |  | x |  |  | x | x | 
| Asthma | Asthma |  |  | x |  |  |  |  | 
| Bronchioloalveolar carcinoma | Bronchioloalveolar carcinoma |  |  |  |  |  | x | x | 
| Cerebral infarction | Cerebral infarction |  |  |  |  |  | x | x | 
| Neck pain | Neck pain |  |  |  |  |  | x | x | 
| Cholecystitis | Cholecystitis |  |  |  |  |  | x | x | 
| Large intestine polyp | Colonic polyp |  |  | x |  |  | x | x | 
| Confusional state | Confusional state |  |  |  |  |  | x | x | 
| Feeling abnormal | Confusional state |  |  |  |  |  | x | x | 
| Malaise |  |  | x |  |  |  | x | 
| Cystitis | Cystitis |  |  | x |  |  |  |  | 
| Bladder pain | Cystitis |  |  | x |  |  |  |  | 
| Cystitis noninfective | Cystitis |  |  | x |  |  |  |  | 
| Sudden death | Sudden death |  |  |  |  |  | x | x | 
| Decubitus ulcer | Decubitus ulcer |  |  | x |  |  |  |  | 
| Dermatitis atopic | Dermatitis atopic |  |  | x |  |  |  |  | 
| Diabetes mellitus | Diabetes mellitus |  |  | x |  |  |  |  | 
| Diplopia | Diplopia |  |  | x |  |  |  |  | 
| Diverticulitis | Diverticulitis |  |  | x |  |  | x | x | 
| Diverticulum | Diverticulum |  |  | x |  |  |  |  | 
| Dysarthria | Dysarthria |  |  |  |  |  | x | x | 
| Osteoarthritis | Dysarthria |  |  |  |  |  | x | x | 
| Ear pain | Ear pain |  |  | x |  |  |  |  | 
| Femur fracture | Femur fracture |  |  |  |  |  | x | x | 
| Femoral neck fracture | Femoral neck fracture |  |  |  |  |  | x | x | 
| Flushing | Flushing |  |  | x |  |  |  |  | 
| Localised infection | Localised infection |  |  |  |  |  | x | x | 
| Gastritis | Gastritis |  |  | x |  |  | x | x | 
| Gastrooesophageal reflux disease | Gastrooesophageal reflux disease |  |  | x |  |  | x | x | 
| Glossodynia | Glossodynia |  |  |  |  |  |  | x | 
| Basedow's disease | Basedow's disease |  |  |  |  |  | x | x | 
| Hallucination | Hallucination |  |  |  |  |  |  | x | 
| Cardiac arrest | Cardiac arrest |  |  |  |  |  | x | x | 
| Haemochromatosis | Haemochromatosis |  |  | x |  |  |  |  | 
| Haemorrhage | Haemorrhage |  |  | x |  |  |  |  | 
| Haemoglobin | Haemorrhage |  |  | x |  |  |  |  | 
| Haemorrhoids | Haemorrhoids |  |  | x |  |  |  |  | 
| Inguinal hernia | Inguinal hernia |  |  |  |  |  | x | x | 
| Herpes simplex | Herpes simplex |  |  | x |  |  |  |  | 
| Herpes virus infection | Herpes virus infection |  |  |  |  |  | x | x | 
| Hip fracture | Hip fracture |  |  |  |  |  | x | x | 
| Hirsutism | Hirsutism |  |  |  |  |  |  | x | 
| Hyperbilirubinaemia | Hyperbilirubinaemia |  |  | x |  |  | x | x | 
| Hypercholesterolaemia | Hypercholesterolaemia |  |  | x |  |  |  |  | 
| Hypernatraemia | Hypernatraemia |  |  |  |  |  | x | x | 
| Hypoglycaemia | Hypoglycaemia |  |  |  |  |  | x | x | 
| Incontinence | Incontinence |  |  | x |  |  |  |  | 
| Kidney infection | Kidney infection |  |  |  |  |  | x | x | 
| Inflammation | Inflammation |  |  | x |  |  |  |  | 
| Influenza | Influenza |  |  | x |  |  | x | x | 
| Intestinal perforation | Intestinal perforation |  |  |  |  |  | x | x | 
| Irritable bowel syndrome | Irritable bowel syndrome |  |  | x |  |  | x | x | 
| Functional gastrointestinal disorder | Irritable bowel syndrome |  |  | x |  |  | x | x | 
| Renal failure acute | Renal failure acute |  |  |  |  |  | x | x | 
| Chronic obstructive pulmonary disease | Chronic obstructive pulmonary disease |  |  | x |  |  |  | x | 
| COPD exacerbation |  |  |  |  |  | x | x | 
| Bronchial hyperreactivity | Chronic obstructive pulmonary disease |  |  | x |  |  |  | x | 
| Lymphoma | Lymphoma |  |  |  |  |  | x | x | 
| Non-Hodgkin's lymphoma | Lymphoma |  |  |  |  |  | x | x | 
| Macular degeneration | Macular degeneration |  |  | x |  |  |  |  | 
| Melaena | Melaena |  |  |  |  |  | x | x | 
| Metrorrhagia | Metrorrhagia |  |  | x |  |  |  |  | 
| Multi-organ failure | Multi-organ failure |  |  | x |  |  | x | x | 
| Nodule | Nodule |  |  |  |  |  | x | x | 
| Ocular hypertension | Ocular hypertension |  |  |  |  |  |  | x | 
| Osteopenia | Osteopenia |  |  | x |  |  |  |  | 
| Pelvic pain | Pelvic pain |  |  |  |  |  | x | x | 
| Periarthritis | Periarthritis |  |  | x |  |  |  |  | 
| Pseudomonas infection | Pseudomonas infection |  |  |  |  |  | x | x | 
| Psychosomatic disease | Psychosomatic disease |  |  | x |  |  |  |  | 
| Pulmonary oedema | Pulmonary oedema |  |  | x |  |  | x | x | 
| Rales | Rales |  |  | x |  |  |  |  | 
| Rib fracture | Rib fracture |  |  | x |  |  | x | x | 
| Sciatica | Sciatica |  |  | x |  |  |  |  | 
| Cardiogenic shock | Cardiogenic shock |  |  |  |  |  | x | x | 
| Septic shock | Septic shock |  |  |  |  |  | x | x | 
| Spinal cord compression | Spinal cord compression |  |  |  |  |  | x | x | 
| Splenic infarction | Splenic infarction |  |  |  |  |  | x | x | 
| Splenomegaly | Splenomegaly |  |  | x |  |  |  |  | 
| Staphylococcal infection | Staphylococcal infection |  |  |  |  |  | x | x | 
| Aphthous stomatitis | Aphthous stomatitis |  |  | x |  |  |  |  | 
| Subarachnoid haemorrhage | Subarachnoid haemorrhage |  |  |  |  |  | x | x | 
| Supraventricular tachycardia | Supraventricular tachycardia |  |  |  |  |  |  | x | 
| Thrombophlebitis | Thrombophlebitis |  |  | x |  |  |  |  | 
| Thrombosis | Thrombosis |  |  |  |  |  | x | x | 
| Upper gastrointestinal haemorrhage | Upper gastrointestinal haemorrhage |  |  |  |  |  | x | x | 
| Presyncope | Syncope vasovagal |  |  | x |  |  |  |  | 
| Vertigo | Vertigo |  |  | x |  |  | x | x | 
| Viraemia | Viraemia |  |  |  |  | x |  |  | 
| Weight increased | Weight increased |  |  | x |  |  |  |  | 
| Wheezing | Wheezing |  |  |  |  |  | x | x | 
| Laceration | Laceration |  |  | x |  |  |  |  | 
| Tachyarrhythmia | Tachyarrhythmia |  |  |  |  |  | x | x | 
| Fungaemia | Fungaemia |  |  |  |  | x |  |  | 
| Rash pustular | Rash pustular |  |  | x |  |  |  |  | 
| Acute sinusitis | Acute sinusitis |  |  |  |  |  | x | x | 
| Cholecystitis acute | Cholecystitis acute |  |  |  |  |  | x | x | 
| Pelvic fracture | Pelvic fracture |  |  |  |  |  | x | x | 
| Urosepsis | Urosepsis |  |  |  |  |  | x | x | 
| Migraine | Migraine |  |  |  |  |  | x | x | 
| Impaired healing | Impaired healing |  |  | x |  |  |  |  | 
| Myocardial ischaemia | Myocardial ischaemia |  |  |  |  |  | x | x | 
| Sinus congestion | Sinus congestion |  |  | x |  |  |  |  | 
| Lung cancer metastatic | Lung cancer metastatic |  |  |  |  |  | x | x | 
| Haemoglobin decreased | Haemoglobin decreased |  |  |  |  |  | x | x | 
| Road traffic accident | Road traffic accident |  |  |  |  |  | x | x | 
| Malaise | Malaise |  |  | x |  |  |  | x | 
| Ill-defined disorder | Malaise |  |  | x |  |  |  | x | 
| Abdominal pain upper | Abdominal pain upper |  |  |  |  |  | x | x | 
| Abdominal tenderness | Abdominal tenderness |  |  | x |  |  |  |  | 
| Small intestinal obstruction | Small intestinal obstruction |  |  |  |  |  | x | x | 
| Hepatotoxicity | Hepatotoxicity |  |  |  |  | x |  | x | 
| Cerebellar infarction | Cerebellar infarction |  |  |  |  |  | x | x | 
| Clostridium difficile colitis | Clostridium difficile colitis |  |  |  |  |  |  | x | 
| Productive cough | Productive cough |  |  | x |  |  |  |  | 
| Frequent bowel movements | Frequent bowel movements |  |  | x |  |  |  |  | 
| Furuncle | Furuncle |  |  | x |  |  |  |  | 
| Azotaemia | Azotaemia |  |  |  |  |  | x | x | 
| Disease progression | Disease progression |  |  |  |  |  | x | x | 
| Ventricular dysfunction | Ventricular dysfunction |  |  |  |  |  | x | x | 
| Cervical vertebral fracture | Cervical vertebral fracture |  |  |  |  |  | x | x | 
| Spinal compression fracture | Spinal compression fracture |  |  | x |  |  | x | x | 
| Renal mass | Renal mass |  |  |  |  |  | x | x | 
| Warm type haemolytic anaemia | Warm type haemolytic anaemia |  |  |  |  |  | x | x | 
| Transfusion reaction | Transfusion reaction |  |  | x |  |  | x | x | 
| Peripheral coldness | Peripheral coldness |  |  | x |  |  |  |  | 
| Mucosal inflammation | Mucosal inflammation |  |  | x |  |  |  |  | 
| Musculoskeletal stiffness | Stiffness |  |  | x |  |  |  |  | 
| Arrhythmia supraventricular | Arrhythmia supraventricular |  |  |  |  |  | x | x | 
| Lymphadenopathy | Lymphadenopathy |  |  | x |  |  |  |  | 
| Visual impairment | Visual disturbance |  |  | x |  |  |  |  | 
| Altered state of consciousness | Depressed level of consciousness |  |  |  |  |  | x | x | 
| Depressed level of consciousness | Depressed level of consciousness |  |  |  |  |  | x | x | 
| Chondrocalcinosis | Chondrocalcinosis |  |  |  |  |  | x | x | 
| Oral infection | Oral infection |  |  |  |  |  | x | x | 
| Gait disturbance | Gait disturbance |  |  |  |  |  | x | x | 
| Cardio-respiratory arrest | Cardio-respiratory arrest |  |  |  |  |  | x | x | 
| Ear infection | Ear infection |  |  |  |  |  | x | x | 
| Dyssomnia | Dyssomnia |  |  | x |  |  |  |  | 
| Enterobacter sepsis | Enterobacter sepsis |  |  |  |  |  | x | x | 
| Limb injury | Limb injury |  |  | x |  |  |  |  | 
| Culture negative | Culture negative |  |  |  |  |  | x |  | 
| Mental status changes | Mental status changes |  |  | x |  |  |  |  | 
| Cardiomyopathy | Cardiomyopathy |  |  |  |  |  | x | x | 
| Prostate cancer metastatic | Prostate cancer metastatic |  |  |  |  |  | x | x | 
| Device related infection | Central line infection |  |  |  |  |  | x | x | 
| Dental discomfort | Dental discomfort |  |  | x |  |  |  |  | 
| Troponin I increased | Troponin I increased |  |  |  |  |  | x | x | 
| Neutrophilic dermatosis | Neutrophilic dermatosis |  |  | x |  |  |  |  | 
| Respiratory failure | Respiratory failure |  |  |  |  |  | x | x | 
| Rhinorrhoea | Rhinorrhoea |  |  | x |  |  |  |  | 
| Excoriation | Abrasion NOS |  |  | x |  |  |  |  | 
| Calculus ureteric | Calculus ureteric |  |  |  |  |  | x | x | 
| Thrombophlebitis superficial | Thrombophlebitis superficial |  |  |  |  |  | x | x | 
| Glioblastoma multiforme | Glioblastoma multiforme |  |  |  |  | x |  |  | 
| Ageusia | Ageusia |  |  | x |  |  |  |  | 
| Gastrointestinal tract irritation | Gastrointestinal tract irritation |  |  | x |  |  |  |  | 
| Somnolence | Somnolence |  |  | x |  |  |  |  |