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More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
Dyskinesia Dyskinesia 16.5% x
Nausea Nausea 5.5% x
Hallucination Hallucination 3.9% x
Confusional state Confusional state 3.7% x
Feeling abnormal Confusional state 3.7% x
Malaise x
Dizziness Dizziness 2.9% x
Syncope x
Depression Depression 2.2% x
Urinary tract infection Urinary tract infection 2.2% x
Headache Headache 2% x
Upper respiratory tract infection Upper respiratory tract infection 1.8% x
Vomiting Vomiting 1.8% x
Back pain Back pain 1.6% x
Dyspnoea Dyspnoea 1.6% x
Dry mouth Dry mouth 1.4% x
Decreased appetite Anorexia 1.2% x
Diarrhoea Diarrhoea 1.2% x
Insomnia Insomnia 1.2% x
Chest pain Chest pain 1% x
Orthostatic hypotension Orthostatic hypotension 1% x
Musculoskeletal pain Shoulder pain 1% x
Muscle spasms Cramp muscle 0.8% x
Paraesthesia Paraesthesia 0.8% x
Pollakiuria Pollakiuria 0.8% x
Dyspepsia Dyspepsia 0.6% x
Heartburn x
Constipation Constipation 0.2% x
Abdominal pain Abdominal pain x
Gastrointestinal pain Abdominal pain x
Gastrointestinal pain x
Agranulocytosis Agranulocytosis x
Alopecia Alopecia x
Anaemia Anaemia x
Angioedema Angioedema x
Anxiety Anxiety x
Asthenia Asthenia x
Fatigue x
Ataxia Ataxia x
Blepharospasm Blepharospasm x
Blister Blister x
Dermatitis bullous Blister x
Bruxism Bruxism x
Chorea Chorea x
Nasopharyngitis Common cold x
Rhinitis Common cold x
Cough Cough x
Dysphagia Dysphagia x
Delusion Delusion x
Diplopia Diplopia x
Duodenal ulcer Duodenal ulcer x
Oedema Oedema x
Dermatitis Rash x
Rash Rash x
Extrapyramidal disorder Extrapyramidal disorder x
Fatigue Fatigue x
Flatulence Flatulence x
Flushing Flushing x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Hiccups Hiccups x
Dysphonia Hoarseness x
Horner's syndrome Horner's syndrome x
Hypersensitivity Hypersensitivity x
Hypertension Hypertension x
Hypotension Hypotension x
Libido increased Libido increased x
Disturbance in sexual arousal Libido increased x
Pain in extremity Leg pain x
Leukopenia Leukopenia x
Malignant melanoma Malignant melanoma x
Mydriasis Mydriasis x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Nervousness Nervousness x
Tension Nervousness x
Neuroleptic malignant syndrome Neuroleptic malignant syndrome x
Nightmare Nightmare x
Hypoaesthesia Numbness x
Sensory loss Numbness x
Pain Pain x
Palpitations Palpitations x
Pemphigus Pemphigus x
Neuropathy peripheral Neuropathy peripheral x
Phlebitis Phlebitis x
Priapism Priapism x
Pruritus Pruritus x
Henoch-Schonlein purpura Henoch-Schonlein purpura x
Convulsion Convulsion x
Salivary hypersecretion Salivary hypersecretion x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Thrombocytopenia Thrombocytopenia x
Tremor Tremor x
Trismus Trismus x
Urinary incontinence Urinary incontinence x
Weight increased Weight increased x
Weight decreased Weight decreased x
Urinary retention Urinary retention x
Agitation Agitation x
Oculogyric crisis Oculogyric crisis x
Blood urea increased Blood urea increased x
Haemoglobin decreased Haemoglobin decreased x
Depression suicidal Depression suicidal x
Malaise Malaise x
Discomfort Malaise x
Ill-defined disorder Malaise x
Muscle twitching Muscle twitching x
Disorientation Disorientation x
Memory impairment Memory impairment x
Euphoric mood Euphoric mood x
Glossodynia Burning tongue x
Psychotic disorder Psychotic episode x
Vision blurred Vision blurred x
Dementia Dementia x
Gait disturbance Gait disturbance x
Menopausal symptoms Hot flush x
Hot flush Hot flush x
Hyperhidrosis Sweating increased x
White blood cell count decreased White blood cell count decreased x
Sleep disorder Sleep disorder x
Somnolence Somnolence x


Information about indications was extracted from the indications and usage sections of the labels.

Carbidopa-Levodopa / SINEMET* CR

Side effects:105

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label