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Cevimeline

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: N07AX03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5
Hyperhidrosis Sweating increased 18.7% 2.4% x x x x x
Headache Headache 14.4% 20.1% x x x x x
Nausea Nausea 13.8% 7.9% x x x x x
Sinusitis Sinusitis 12.3% 10.9% x x x x x
Upper respiratory tract infection Upper respiratory tract infection 11.4% 9.1% x x x
Rhinitis Rhinitis 11.2% 5.4% x x x x x
Diarrhoea Diarrhoea 10.3% 10.3% x x x x x
Dyspepsia Dyspepsia 7.8% 8.5% x x x x x
Abdominal pain Abdominal pain 7.6% 6.7% x x x x x
Gastrointestinal pain Abdominal pain 7.6% 6.7% x x x x x
Cough Cough 6.1% 3% x x x x x
Urinary tract infection Urinary tract infection 6.1% 3% x x x x
Pharyngitis Pharyngitis 5.2% 5.4% x x x x x
Vomiting Vomiting 4.6% 2.4% x x x x x
Back pain Back pain 4.5% 4.2% x x x x x
Conjunctivitis Conjunctivitis 4.3% 3.6% x x x x x
Dermatitis Rash 4.3% 6% x x x x x
Dermatitis x x x x x
Rash Rash 4.3% 6% x x x x x
Bronchitis Bronchitis 4.1% 1.2% x x x x x
Dizziness Dizziness 4.1% 7.3% x x x x x
Syncope x x x x x
Arthralgia Arthralgia 3.7% 1.8% x x x x x
Musculoskeletal discomfort Arthralgia 3.7% 1.8% x x x x x
Myalgia x x x x
Asthenia Fatigue 3.3% 1.2% x x x x x
Asthenia 0.5% 0% x x x x x
Fatigue Fatigue 3.3% 1.2% x x x x x
Pain Pain 3.3% 3% x x x x x
Surgery Surgical intervention 3.3% 3% x x x x
Bone pain Bone pain 2.8% 1.8% x x x x x
Menopausal symptoms Hot flush 2.4% 0% x x x x x
Hot flush Hot flush 2.4% 0% x x x x x
Insomnia Insomnia 2.4% 1.2% x x x x x
Salivary hypersecretion Salivary hypersecretion 2.2% 0.6% x x x x x
Anxiety Anxiety 1.3% 1.2% x x x x x
Chills Rigors 1.3% 1.2% x x x x x
Pollakiuria Pollakiuria 0.9% 1.8% x x x x
Flushing Flushing 0.3% 0.6% x x x x x
Polyuria Polyuria 0.1% 0.6% x x x x x
Urine output increased Polyuria 0.1% 0.6% x x x x x
Cholecystitis Cholecystitis postmarketing x x x x
Abscess Abscess x x x x
Agranulocytosis Agranulocytosis x x x x x
Albuminuria Albuminuria x x x x x
Alopecia Alopecia x x x x x
Amenorrhoea Amenorrhoea x x x x x
Amnesia Amnesia x x x x x
Anaemia Anaemia x x x x
Hypochromic anaemia Hypochromic anaemia x x x x x
Angina pectoris Angina pectoris x x x x x
Decreased appetite Anorexia x x x x
Aphasia Aphasia x x x x x
Apnoea Apnoea x x x x x
Appendicitis Appendicitis x x x x x
Arrhythmia Arrhythmia x x x x x
Arthritis Arthritis x x x x x
Arthritis aggravated x x x x x
Asthma Asthma x x x x x
Atelectasis Atelectasis x x x x x
Pneumothorax Atelectasis x x x x x
Bacterial infection Bacterial infection x x x x x
Blepharitis Blepharitis x x x x x
Bone disorder Bone disorder x x x x x
Bronchospasm Bronchospasm x x x x x
Bronchoconstriction x
Bundle branch block Bundle branch block x x x x x
Bursitis Bursitis x x x x x
Candida infection Candida infection x x x x
Basal cell carcinoma Basal cell carcinoma x x x x x
Squamous cell carcinoma Squamous cell carcinoma x x x x x
Cardiovascular disorder Cardiovascular disorder x x x x x
Carpal tunnel syndrome Carpal tunnel syndrome x x x x x
Cellulitis Cellulitis x x x x x
Chest pain Chest pain x x x x
Retrosternal pain x x x x x
Precordial pain x x x x x
Choking Choking x x x x x
Cholelithiasis Cholelithiasis x x x x x
Colitis ulcerative Colitis ulcerative x x x x x
Proctocolitis Colitis ulcerative x x x x x
Coma Coma x x x x x
Infection Infection x x x x
Confusional state Confusional state x x x x x
Feeling abnormal Confusional state x x x x x
Malaise x x x x x
Constipation Constipation x x x x
Corneal opacity Corneal opacity x x x x x
Ulcerative keratitis Ulcerative keratitis x x x x x
Cystitis Cystitis x x x x
Bladder pain Cystitis x x x x
Cystitis noninfective Cystitis x x x x
Deafness Deafness x x x x x
Dysphagia Dysphagia x x x x x
Dehydration Dehydration x x x x x
Delirium Delirium x x x x x
Delusion Delusion x x x x x
Dental caries Dental caries x x x x x
Depersonalisation Depersonalisation x x x x x
Dermatitis contact Dermatitis contact x x x x x
Scleroderma Scleroderma x x x x x
Diabetes mellitus Diabetes mellitus x x x x x
Diplopia Diplopia x x x x x
Joint dislocation Joint dislocation x x x x x
Diverticulitis Diverticulitis x x x x x
Duodenitis Duodenitis x x x x x
Dysgeusia Dysgeusia x x x x x
Dyskinesia Dyskinesia x x x x x
Dysmenorrhoea Dysmenorrhoea x x x x x
Dyspnoea Dyspnoea x x x x x
Dysuria Dysuria x x x x x
Strangury x x x x x
Ear pain Ear pain x x x x
Eczema Eczema x x x x x
Oedema Oedema x x x x x
Endocrine disorder Endocrine disorder x x x x x
Enterocolitis Enterocolitis x x x x x
Eosinophilia Eosinophilia x x x x x
Epididymitis Epididymitis x x x x x
Epistaxis Epistaxis x x x x
Eructation Eructation x x x x
Oesophageal stenosis Oesophageal stenosis x x x x x
Oesophagitis Oesophagitis x x x x x
Congenital eye disorder Congenital eye disorder x x x x
Eye disorder Congenital eye disorder x x x x
Eye haemorrhage Eye haemorrhage x x x x x
Eye infection Eye infection x x x x
Failure to thrive Failure to thrive x x x x x
Body temperature increased Body temperature increased x x x x
Flatulence Flatulence x x x x
Food poisoning Food poisoning x x x x x
Furuncle Furunculosis x x x x x
Gastritis Gastritis x x x x x
Gastroenteritis Gastroenteritis x x x x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x x x x
Gingival hyperplasia Gingival hyperplasia x x x x x
Gingivitis Gingivitis x x x x x
Glaucoma Glaucoma x x x x x
Glossitis Glossitis x x x x x
Tongue geographic Tongue geographic x x x x x
Glycosuria Glycosuria x x x x x
Goitre Goitre x x x x x
Gout Gout x x x x x
Hallucination Hallucination x x x x x
Hearing impaired Partial hearing loss x x x x x
Cardiac disorder Cardiac disorder x x x x x
Cardiomegaly Cardiomegaly x x x x x
Cardiac murmur Cardiac murmur x x x x x
Heat stroke Heat stroke x x x x x
Blood disorder Blood disorder x x x x x
Haematoma Haematoma x x x x x
Haematuria Haematuria x x x x x
Haemoptysis Haemoptysis x x x x x
Haemorrhage Haemorrhage x x x x x
Haemoglobin Haemorrhage x x x x x
Haemorrhoids Haemorrhoids x x x x x
Herpes simplex Herpes simplex x x x x x
Herpes zoster Herpes zoster x x x x x
Hiccups Hiccups x x x x
Hypercalcaemia Hypercalcaemia x x x x x
Hypercholesterolaemia Hypercholesterolaemia x x x x x
Hyperaesthesia Hyperaesthesia x x x x x
Hyperglycaemia Hyperglycaemia x x x x x
Hyperkalaemia Hyperkalaemia x x x x x
Hyperlipidaemia Hyperlipidaemia x x x x x
Hypersensitivity Hypersensitivity x x x x
Allergy aggravated x x x x x
Hypertension Hypertension x x x x x
Hypertension worsened x x x x x
Hypertriglyceridaemia Hypertriglyceridaemia x x x x x
Blood triglycerides increased Hypertriglyceridaemia x x x x x
Salivary gland enlargement Salivary gland enlargement x x x x
Hypoaesthesia Hypoaesthesia x x x x
Hypoglycaemia Hypoglycaemia x x x x x
Hypokalaemia Hypokalaemia x x x x x
Hyponatraemia Hyponatraemia x x x x x
Hypotension Hypotension x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x
Hypothyroidism Hypothyroidism x x x x x
Illusion Illusion x x x x x
Intestinal obstruction Intestinal obstruction x x x x x
Irritable bowel syndrome Irritable bowel syndrome x x x x x
Functional gastrointestinal disorder Irritable bowel syndrome x x x x x
Arthropathy Arthropathy x x x x x
Osteoarthritis Arthropathy x x x x x
Keratitis Keratitis x x x x x
Keratoconjunctivitis x x x x x
Nephrolithiasis Calculus of kidney x x x x x
Laryngitis Laryngitis x x x x x
Muscle spasms Cramps of lower extremities x x x x
Pain in extremity Leg pain x x x x x
Leukocytosis Leukocytosis x x x x x
Leukopenia Leukopenia x x x x x
Vaginal discharge Leukorrhea x x x x x
Lichen planus Lichen planus x x x x x
Chronic obstructive pulmonary disease Chronic obstructive pulmonary disease x x x x x
Bronchial hyperreactivity Chronic obstructive pulmonary disease x x x x x
Lymphocytosis Lymphocytosis x x x x x
Melaena Melaena x x x x x
Menorrhagia Menorrhagia x x x x x
Menstrual disorder Menstrual disorder x x x x x
Metrorrhagia Metrorrhagia x x x x x
Motion sickness Motion sickness x x x x x
Multiple sclerosis Multiple sclerosis x x x x x
Hypertonia Hypertonia x x x x
Musculoskeletal disorder Musculoskeletal disorder x x x x x
Fungal infection Fungal infection x x x x
Mydriasis Mydriasis x x x x x
Myocardial infarction Myocardial infarction x x x x x
Acute coronary syndrome Myocardial infarction x x x x x
Myopia Myopia x x x x x
Nail disorder Nail disorder x x x x x
Neoplasm Neoplasm x x x x x
Nephrotic syndrome Nephrosis x x x x x
Nervous system disorder Nervous system disorder x x x x x
Neuralgia Neuralgia x x x x x
Neurosis Neurosis x x x x x
Nightmare Nightmare x x x x x
Nocturia Nocturia x x x x x
Oliguria Oliguria x x x x x
Mouth haemorrhage Mouth haemorrhage x x x x x
Osteomyelitis Osteomyelitis x x x x x
Osteoporosis Osteoporosis x x x x x
Otitis media Otitis media x x x x
Ovarian cyst Ovarian cyst x x x x x
Ovarian disorder Ovarian disorder x x x x x
Procedural pain Postoperative pain x x x x
Pallor Pallor x x x x x
Palpitations Palpitations x x x x
Paraesthesia Paraesthesia x x x x x
Paronychia Paronychia x x x x x
Onychia x x x x x
Peptic ulcer Peptic ulcer x x x x x
Pericarditis Pericarditis x x x x x
Personality disorder Personality disorder x x x x x
Pleural effusion Pleural effusion x x x x x
Pleurisy Pleurisy x x x x x
Pneumonia Pneumonia x x x x
Post procedural haemorrhage Postoperative hemorrhage x x x x x
Prostatic disorder Prostatic disorder x x x x x
Pruritus Pruritus x x x x
Pruritus genital Pruritus genital x x x x x
Pulmonary embolism Pulmonary embolism x x x x x
Pulmonary fibrosis Pulmonary fibrosis x x x x x
Purpura Purpura x x x x x
Vascular purpura Purpura x x x x x
Pyelonephritis Pyelonephritis x x x x x
Pyuria Pyuria x x x x x
Anorectal disorder Rectal disorder x x x x x
Retinal disorder Retinal disorder x x x x x
Rosacea Rosacea x x x x x
Scleritis Scleritis x x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis x x x x x
Convulsion Convulsion x x x x x
Sialoadenitis Sialoadenitis x x x x
Skin disorder Skin disorder x x x x
Skin ulcer Skin ulcer x x x x x
Speech disorder Speech disorder x x x x x
Gastric ulcer Gastric ulcer x x x x x
Stomatitis Stomatitis x x x x x
Mouth ulceration Ulcerative stomatitis x x x x
Shock Syncope x x x x x
Syncope Syncope x x x x x
Loss of consciousness Syncope x x x x x
Synovitis Synovitis x x x x x
Tachycardia Tachycardia x x x x x
Supraventricular tachycardia Supraventricular tachycardia x x x x x
Tendonitis Tendonitis x x x x x
Tenosynovitis Tenosynovitis x x x x x
Thirst Thirst x x x x x
Thrombocytopenia Thrombocytopenia x x x x x
Thrombophlebitis Thrombophlebitis x x x x x
Costochondritis Costochondritis x x x x x
Onychomycosis Onychomycosis x x x x x
Tinnitus Tinnitus x x x x x
Tongue disorder Tongue disorder x x x x x
Tooth disorder Tooth disorder x x x x
Toothache Toothache x x x x
Tremor Tremor x x x x
Urethral disorder Urethral disorder x x x x x
Urinary incontinence Urinary incontinence x x x x x
Micturition disorder Micturition disorder x x x x x
Urticaria Urticaria x x x x x
Uterine haemorrhage Uterine haemorrhage x x x x x
Vaginal inflammation Vaginal inflammation x x x x
Vaginal infection Vaginal inflammation x x x x
Angiopathy Angiopathy x x x x x
Vasculitis Vasculitis x x x x x
Vertigo Vertigo x x x x
Hepatitis viral Hepatitis viral x x x x x
Viral infection Viral infection x x x x x
Vitreous detachment Vitreous detachment x x x x x
Skin papilloma Common wart x x x x x
Weight increased Weight increased x x x x x
Weight decreased Weight decreased x x x x x
Injury Trauma x x x x x
Xerophthalmia Xerophthalmia x x x x
Yawning Yawning x x x x x
Urinary retention Urinary retention x x x x x
Urogenital disorder Urogenital disorder x x x x x
Agitation Agitation x x x x x
Hyperkinesia x x x x x
Apathy Apathy x x x x x
Flat affect Apathy x x x x x
Mood swings Mood swings x x x x x
Affect lability Mood swings x x x x x
Photopsia Photopsia x x x x x
Oedema peripheral Oedema peripheral x x x x
Cataract Cataract x x x x x
Plantar fasciitis Plantar fasciitis x x x x x
Migraine Migraine x x x x
Periorbital oedema Periorbital oedema x x x x x
Amylase increased Amylase increased x x x x
Blood urea increased Blood urea increased x x x x x
Tongue discolouration Tongue discolouration x x x x x
Electrolyte imbalance Electrolyte abnormality x x x x x
Blood electrolytes abnormal Electrolyte abnormality x x x x x
Endometrial disorder Endometrial disorder x x x x x
Skin hypertrophy Skin hypertrophy x x x x x
Renal impairment Kidney function abnormal x x x x x
Mania Manic psychosis x x x x
Muscular weakness Muscular weakness x x x x x
Eye pain Eye pain x x x x
Paranoia Paranoid reaction x x x x x
Blood alkaline phosphatase increased Phosphatase alkaline increased x x x x x
Platelet disorder Abnormal platelets x x x x x
Hyporeflexia Hyporeflexia x x x x
Alanine aminotransferase increased Alanine aminotransferase increased x x x x x
Skin discolouration Skin discolouration x x x x x
Dry skin Dry skin x x x x x
Malnutrition Malnutrition x x x x x
Photosensitivity reaction Photosensitivity reaction x x x x x
Lichenoid keratosis Eruption lichenoid x x x x x
Nail discolouration Nail discolouration x x x x x
Atrophic vulvovaginitis Vaginitis atrophic x x x x x
Malaise Malaise x x x x x
Discomfort Malaise x x x x x
Ill-defined disorder Malaise x x x x x
Myalgia Myalgia x x x x
Increased appetite Increased appetite x x x x x
Proctalgia Rectal tenesmus x x x x x
Rectal tenesmus Rectal tenesmus x x x x x
Anorectal discomfort Rectal tenesmus x x x x x
Thinking abnormal Thinking abnormal x x x x x
Mental disability Thinking abnormal x x x x x
Rash erythematous Rash erythematous x x x x
Muscle contractions involuntary Muscle contractions involuntary x x x x x
Salivary gland pain Salivary gland pain x x x x
Tongue ulceration Tongue ulceration x x x x x
Peripheral ischaemia Peripheral ischaemia x x x x x
Lymphadenopathy Lymphadenopathy cervical x x x x x
Lymphadenopathy x x x x x
Urine abnormality Urine abnormality x x x x x
Urine analysis abnormal Urine abnormality x x x x x
Rheumatoid arthritis Rheumatoid arthritis aggravated x x x x x
Dermatitis bullous Bullous eruption x x x x x
Haemoglobinaemia Hyperhemoglobinemia x x x x x
Cold sweat Skin cold clammy x x x x x
Depression Depression aggravated x x x x x
Crying Crying abnormal x x x x x
Retinal deposits Retinal deposits x x x x x
Periodontal destruction Periodontal destruction x x x x x
Oedema mouth Oedema mouth x x x x x
Skin exfoliation Skin exfoliation x x x x x
Strangury Strangury x x x x x
Pulmonary congestion Pulmonary congestion x x x x x
Respiratory tract congestion Pulmonary congestion x x x x x
Erectile dysfunction Erectile dysfunction x x x x x
Sepsis Sepsis x x x x x
Nasal ulcer Nasal ulcer x x x x x
Hyperproteinaemia Hyperproteinaemia x x x x x
Cholinergic syndrome Cholinergic syndrome x x x x x
Toxicity to various agents Cholinergic syndrome x x x x x
Change of bowel habit Change of bowel habit x x x x x
Mucosal inflammation Mucosal inflammation x x x x x
Extrasystoles Extrasystoles x x x x x
Genital candidiasis Genital candidiasis x x x x x
Abdominal distension Enlargement abdomen x x x x x
Influenza like illness Influenza-like symptoms x x x x
Dysaesthesia Dysaesthesia x x x x x
Systemic lupus erythematosus Lupus erythematosus x x x x x
Osteonecrosis Avascular necrosis femoral head x x x x x
Hyperkinesia Hyperkinesia x x x x x
Neuropathy peripheral Neuropathy x x x x x
Dementia Dementia x x x x x
Electrocardiogram T wave inversion Electrocardiogram T wave inversion x x x x x
Coordination abnormal Coordination abnormal x x x x x
Electrocardiogram abnormal Electrocardiogram abnormal x x x x x
Paralysis Paralysis x x x x x
Face oedema Face oedema x x x x x
Bladder discomfort Bladder discomfort x x x x x
Blood pressure fluctuation Blood pressure fluctuation x x x x x
Urine flow decreased Urine flow decreased x x x x x
Sexual dysfunction Sexual dysfunction x x x x x
Breast pain Breast pain female x x x x x
Renal pain Renal pain x x x x x
Gait disturbance Gait disturbance x x x x x
Blood uric acid increased Hyperuricaemia x x x x x
Hyperuricaemia Hyperuricaemia x x x x x
Phlebitis superficial Phlebitis superficial x x x x x
Thrombocytosis Thrombocytosis x x x x x
Thrombocytopenic purpura Thrombocytopenic purpura x x x x x
Hyperkeratosis Hyperkeratosis x x x x x
Ileus Ileus x x x x x
Aggression Aggressive reaction x x x x x
Breast neoplasm Breast neoplasm x x x x x
Parosmia Parosmia x x x x x
Dysphonia Dysphonia x x x x x
Somnolence Somnolence x x x x x
Vaginal haemorrhage Vaginal haemorrhage x x x x x
Visual impairment Abnormal vision x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CEVIMELINE

Side effects:325
Source:FDA Structured Product Label

CEVIMELINE HYDROCHLORIDE / EVOXAC

Side effects:367
Source:FDA

CEVIMELINE

Side effects:371
Source:FDA Structured Product Label

CEVIMELINE

Side effects:372
Source:FDA Structured Product Label

CEVIMELINE

Side effects:372
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label