Clonazepam

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 14)
1 2 3 4 5 6 7 8 9 10
Somnolence def Somnolence def 1% - 50% 1% - 10% x x x x x x x
Drowsiness def x x x x x x x x x x
Infection def Infection def 0% - 10% 0% - 4% x x x x x x x
Respiratory tract infection def Respiratory tract infection def 6% - 10% 4% x x x x x
Upper respiratory tract infection def Upper respiratory tract infection def 6% - 10% 4% x x x x x
Asthenia def Fatigue def 6% - 9% 4% x x x x x x x
Weakness def x x x x x x x x x x
Fatigue def Fatigue def 6% - 9% 4% x x x x x x x
Lassitude def x
Coordination abnormal Coordination abnormal 1% - 9% 0% x x x x x x
Ataxia def Ataxia def 0% - 8% 0% x x x x x x x x x x
Sinusitis def Sinusitis def 2% - 8% 3% x x x x x x
Dysmenorrhoea def Dysmenorrhoea def 0% - 6% 1% - 2% x x x x x x
Constipation def Constipation def 0% - 5% 2% x x x x x x x x x x
Influenza def Influenza def 2% - 5% 3% x x x x x x
Memory impairment def Memory impairment def 2% - 5% 2% x x x x x x
Forgetfulness x x
Cough def Cough def 0% - 4% 0% x x x x x x
Dysarthria def Dysarthria def 0% - 4% 0% x x x x x x x x x x
Slurred speech x x x x x x x x x
Osteoarthritis def Dysarthria def 0% - 4% 0% x x x x x x x x x x
Hypersensitivity def Hypersensitivity def 1% - 4% 1% x x x x x x x
Nervousness def Nervousness def 0% - 4% 0% - 2% x x x x x x x x
Tension def Nervousness def 0% - 4% 0% - 2% x x x x x x x x
Rhinitis def Rhinitis def 2% - 4% 1% x x x x x x
Vaginal inflammation def Vaginal inflammation def 0% - 4% 1% x x x x x x
Vaginal infection def Vaginal inflammation def 0% - 4% 1% x x x x x x
Myalgia def Myalgia def 0% - 4% 1% x x x x x x
Musculoskeletal discomfort Myalgia def 0% - 4% 1% x x x x x x
Arthralgia def x x x x x x x
Libido decreased def Libido decreased def 0% - 3% 0% x x x x x x
Disturbance in sexual arousal Libido decreased def 0% - 3% 0% x x x x x x
Libido increased def x x x x x x x
Pharyngitis def Pharyngitis def 1% - 3% 1% x x x x x x
Decreased appetite Decreased appetite 0% - 3% 1% x x x x x x
Anorexia def x x x x x x x x x x
Ejaculation delayed Ejaculation delayed 0% - 3% 0% x x x x x x
Erectile dysfunction def Erectile dysfunction def 0% - 3% 0% x x x x x
Vision blurred def Vision blurred def 0% - 3% 1% x x x x x x
Abdominal pain def Abdominal pain def 0% - 2% 1% x x x x x x x x x
Gastrointestinal pain def Abdominal pain def 0% - 2% 1% x x x x x x x x x
Bronchitis def Bronchitis def 0% - 2% 1% x x x x x x
Confusional state def Confusional state def 0% - 2% 0% x x x x x x x x x x
Feeling abnormal Confusional state def 0% - 2% 0% x x x x x x x x x x
Malaise def x x x x x x x
Pollakiuria def Pollakiuria def 0% - 2% 0% x x x x x x
Urinary tract infection def Urinary tract infection def 0% - 2% 0% x x x x x x
Mood swings Mood swings 0% - 2% 1% x x x x x x
Affect lability Mood swings 0% - 2% 1% x x x x x x
Ageusia def Ageusia def x x x x x x x
Aggression def Aggression def x x x x x x x x x x
Aggressive reaction x x x x x x x
Alcohol poisoning Alcohol intoxication def x x x x x x x
Alopecia def Alopecia def x x x x x x x x x x
Amnesia def Amnesia def x x x x x x x x
Anaphylactic shock def Anaphylactic shock def x
Anaemia def Anaemia def x x x x x x x x x x
Anxiety def Anxiety def x x x x x x x x
Aphonia def Aphonia def x x x x x x x x x x
Arthralgia def Arthralgia def x x x x x x x
Knee pain x x x x x x x
Painful ankle x x x x x x x
Asthma def Asthma def x x x x x x x
Asthmatic attack x x x x x x x
Back pain def Back pain def x x x x x x x x x x
Low back pain def x x x x x x x x x x
Mental disorder def Mental disorder def x x x x x x x
Coagulopathy def Coagulopathy def x x x x x x x
Candidiasis def Candidiasis def x x x x x x x
Cardiovascular disorder def Cardiovascular disorder def x x x x x x x
Cellulitis def Cellulitis def x x x x x x x
Chorea def Chorea def x x x x x x x x x x
Tongue coated Tongue coated x x x x x x x x x x
Coma def Coma def x x x x x x x x x x
Cystitis def Cystitis def x x x x x x x
Bladder pain def Cystitis def x x x x x x x
Cystitis noninfective def Cystitis def x x x x x x x
Dehydration def Dehydration def x x x x x x x x x x
Delusion def Delusion def x
Dermatitis def Dermatitis def x x x x x x x
Rash def x x x x x x x x x x
Dermatitis contact def Dermatitis contact def x x x x x x x
Diarrhoea def Diarrhoea def x x x x x x x x x x
Diplopia def Diplopia def x x x x x x x x x x
Dyspepsia def Dyspepsia def x x x x x x x
Heartburn def x x x x x x x
Dysuria def Dysuria def x x x x x x x x x x
Ear pain def Ear pain def x x x x x x x
Oedema def Oedema def x x x x x x x x
Enuresis def Enuresis def x x x x x x x x x x
Eosinophilia def Eosinophilia def x x x x x x x x x x
Epistaxis def Epistaxis def x x x x x x x
Rash def Rash def x x x x x x x x x x
Body temperature increased def Body temperature increased def x x x x x x x x x x
Flatulence def Flatulence def x x x x x x x
Pain in extremity def Foot pain x x x x x x x
Gastritis def Gastritis def x x x x x x x
Gout def Gout def x x x x x x x
Gynaecomastia def Gynaecomastia def x x x
Hallucination def Hallucination def x x x x x x x x x x
Headache def Headache def x x x x x x x x x x
Headache fullness x x x x x x x
Cardiac arrest def Cardiac arrest def x
Cardiac failure def Cardiac failure def x
Hemiparesis Hemiparesis x x x x x x x x x x
Haemorrhage def Haemorrhage def x x x x x x x
Haemoglobin def Haemorrhage def x x x x x x x
Haemorrhoids def Haemorrhoids def x x x x x x x
Hepatomegaly def Hepatomegaly def x x x x x x x x x
Herpes virus infection def Herpes NOS def x x x x x x x
Herpes simplex def Herpes simplex def x x x x x x x
Hirsutism def Hirsutism def x x x x x x x x x x
Dysphonia def Hoarseness def x x x x x x x
Hordeolum def Hordeolum def x x x x x x x
Hostility def Hostility def x x x x x x x x
Hunger def Hunger def x x x x x x x
Hypoaesthesia def Hypoaesthesia def x x x x x x x
Hypotension def Hypotension def x x x x x x x
Orthostatic hypotension def Orthostatic hypotension def x x x x x x x
Conversion disorder def Hysteria def x x x x x x x
Illusion def Illusion def x x x x x x x
Incontinence def Incontinence def x x x x x x x x x x
Libido increased def Libido increased def x x x x x x x
Infectious mononucleosis def Infectious mononucleosis def x x x x x x x
Inflammation def Inflammation def x x x x x x x
Inflammation localised x x x x x x x
Irritability def Irritability def x x x x x x x x x x
Muscle spasms def Cramps of lower extremities x x x x x x x
Cramp muscle def x x x x x x x
Leukopenia def Leukopenia def x x x x x x x x x x
Breast pain def Breast pain def x x x x x x x
Motion sickness def Motion sickness def x x x x x x x
Hypertonia def Hypertonia def x x x x x x x
Hypotonia def Hypotonia def x x x x x x x x x x
Muscle relaxant therapy Hypotonia def x x x x x x x x x x
Musculoskeletal disorder def Musculoskeletal disorder def x x x x x x x
Fungal infection def Fungal infection def x x x x x x
Nervous system disorder def Nervous system disorder def x x x x x x x
Nightmare def Nightmare def x x x x x x x x
Nocturia def Nocturia def x x x x x x x x x x
Nystagmus def Nystagmus def x x x x x x x x x x
Ear infection def Otitis def x x x x x x x
Tropical spastic paresis def Tropical spastic paresis def x x x x x x x
Paresis def Paresis def x x x x x x x
Pelvic pain def Pelvic pain def x x x x x x x
Neuropathy peripheral def Neuropathy peripheral def x x x x x x x
Pigmentation disorder def Pigmentation def x
Pleurisy def Pleurisy def x x x x x x x
Pneumonia def Pneumonia def x x x x x x x
Polyuria def Polyuria def x x x x x x x
Urine output increased Polyuria def x x x x x x x
Pruritus def Pruritus def x x x x x x x x x x
Psychotic disorder def Psychotic disorder def x x x x x x x x
Puberty def Puberty def x
Precocious puberty def Precocious puberty def x
Anger def Rage def x
Respiratory disorder def Respiratory disorder def x x x x x x x
Salivary hypersecretion def Salivation def x x x
Salivary hypersecretion def x x x x x x x x x x
Scotoma def Scotoma def x x x x x x x
Chills def Shivering def x x x x x x x
Skin disorder def Skin disorder def x x x x x x x
Sleep disorder def Sleep disturbance x x x x x x x x
Sleep disorder def x x x x x x x
Sneezing def Sneezing def x x x x x x x
Sneezing excessive x x x x x x x
Gastric disorder def Gastric disorder def x x x x x x x
Completed suicide Suicide def x x x x x x x
Swelling def Swelling def x x x x x x x x x
Tendonitis def Tendonitis def x x x x x x x
Thirst def Thirst def x x x x x x x
Thrombocytopenia def Thrombocytopenia def x x x x x x x x x
Thrombophlebitis def Thrombophlebitis def x x x x x x x
Thrombophlebitis of the leg x x x x x x x
Tooth disorder def Tooth disorder def x x x x x x x
Toothache def Toothache def x x x x x x x
Tremor def Tremor def x x x x x x x x x x
Urinary incontinence def Urinary incontinence def x x x x x x x x
Urethral disorder def Urinary tract disorder def x x x x x x x
Urinary tract disorder def Urinary tract disorder def x x x x x x x
Urticaria def Urticaria def x x x
Vertigo def Vertigo def x x x x x x x x x x
Viral infection def Viral infection def x x x x x x x
Vomiting def Vomiting def x x x
Weight increased def Weight increased def x x x x x x x x x
Weight decreased def Weight decreased def x x x x x x x x
Xeroderma def Xeroderma def x x x x x x x
Xerophthalmia def Xerophthalmia def x x x x x x x
Dry mouth def Dry mouth def x x x x x x x x x x
Yawning def Yawning def x x x x x x x
Urinary retention def Urinary retention def x x x x x x x x x x
Akinesia Akinesia x x x
Agitation def Agitation def x x x x x x x x x x
Excitement x x x x x x x
Excitability x x x x x x x x
Hyperkinesia def x x x x x x x x x
Apathy def Apathy def x x x x x x x
Flat affect Apathy def x x x x x x x
Depressive symptom Depressive symptom x x x x x x
Migraine def Migraine def x x x x x x x
Periorbital oedema def Periorbital oedema def x x x x x x x
Depressed level of consciousness def CNS depression NOS x x x x x x x x x x
Swelling face Swelling face x x
Tongue disorder Tongue oedema x x x x x x x
Tongue oedema Tongue oedema x x x x x x x
Muscular weakness def Muscular weakness def x x x x x x x x x x
Respiratory moniliasis Respiratory moniliasis x
Menstruation irregular def Menstruation irregular def x x x x x x x
Endometrial sarcoma Endometrial stromal sarcoma def x
Malaise def Sickness x x x x x x x
Malaise def x x x x x x x
Discomfort def Malaise def x x x x x x x
Ill-defined disorder Malaise def x x x x x x x
Muscle twitching def Muscle twitching def x x x x x x x
Gait disturbance def Unsteady gait x x
Increased appetite Increased appetite x x x x x x x x x x
Abdominal discomfort Abdominal discomfort x x x x x x
Upset stomach x x x x x x x
Bladder dysfunction Bladder dysfunction x x x x x x x
Disorientation Disorientation x
Anterograde amnesia def Anterograde amnesia def x
Tenderness def Tenderness def x x x x x x x
Cerebellar syndrome def Dysdiadochokinesis x x x x x x x x x
Respiratory depression Respiratory depression x x x x x x x x x
Pulmonary function test decreased Respiratory depression x x x x x x x x x
Appetite disorder Hunger abnormal x x x x x x x
Euphoric mood def Euphoric mood def x x
Disturbance in attention Cerebration impaired def x
Mental disability Cerebration impaired def x
Ejaculation failure Ejaculation decreased x x x x x x
Eye irritation Eye irritation x x x x x x x
Oedema peripheral def Ankle edema x x x x x x x
Pedal edema def x x x x x x x
Joint swelling Ankle edema x x x x x x x
Swelling of knees x x x x x x x
Haemorrhage urinary tract def Haemorrhage urinary tract def x x x x x x x
Pain in jaw Pain in jaw x x x x x x x
Gingival pain def Gingival pain def x x x x x x x
Skin burning sensation def Skin burning sensation def x x x x x x x
Pulmonary congestion Pulmonary congestion x x x x x x x x
Respiratory tract congestion Pulmonary congestion x x x x x x x x
Dependence def Dependence physiological def x
Abnormal dreams Vivid dreams x x x x x x x x
Platelet count decreased Platelet count decreased x
Rash maculo-papular def Rash maculo-papular def x
Hyperkinesia def Hyperkinesia def x x x x x x x x x
Disinhibition Disinhibition x x x x x x x
Lymphadenopathy def Lymphadenopathy def x x x x x x x x x
Eye movement disorder def Abnormal eye movements NOS x x x x x x x
Urine colour abnormal def Urine colour abnormal def x x x x x x x
Chromaturia Urine colour abnormal def x x x x x x x
Feeling drunk Feeling drunk x x
Face oedema def Face oedema def x x x x x x x x
Visual impairment def Visual disturbance x x x x x x
Emotional distress def Emotional distress def x x x x x x x
Acne def Acne def x x x x x x x
Insomnia def Insomnia def x x x x x x x x x x
Nasopharyngitis def Rhinorrhoea def x x x x x x x x x x
Rhinorrhoea def Rhinorrhoea def x x x x x x x x x x
Encopresis Encopresis x x x x x x x x x x
Loss of libido Loss of libido x x x x x x x x
Indication Labels
Abdominal distress x x x x x x x
Agoraphobia def x x x x x x x
Akinetic seizures x x
Chest pain def x x x x x x x
Chills def x x x x x x x
Choking def x x x x x x x
Depersonalisation def x x x x x x x
Derealisation def x x x x x x x
Discomfort def x x x x x x x
Dizziness def x x x x x x x
Dyspnoea def x x x x x x x
Epilepsy def x x x x x x x
Fear x x x x x x x
Fear of death x x x x x x x
Flushing def x x x x x x x
Heart pounding x x x x x x x
Hot flush def x x x x x x
Lennox-Gastaut syndrome def x x x x x x x x
Lightheadedness x x x x x x x
Myoclonic epilepsy def x x x x x
Nausea def x x x x x x x
Numbness def x x x x x x x
Pain def x x x x x x x
Palpitations def x x x x x x x
Panic attack def x x x x x x x
Panic disorder def x x x x x x x
Panic reaction def x x x x x x x
Paraesthesia def x x x x x x x
Petit mal epilepsy def x x x x x x x x
Seizures def x x x x x x x x
Sweating def x x x x x x x
Tingling sensation def x x x x x x x
Trembling x x x x x x x
Worry def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N03AE01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. CLONAZEPAM / PRO-CLONAZEPAM : 64 side effects (Health Canada)
  2. CLONAZEPAM / CLONAPAM : 67 side effects (Health Canada)
  3. CLONAZEPAM / RIVOTRIL 0.5TAB : 87 side effects (Health Canada)
  4. CLONAZEPAM : 180 side effects (FDA XML label)
  5. CLONAZEPAM : 199 side effects (FDA XML label)
  6. CLONAZEPAM : 202 side effects (FDA XML label)
  7. CLONAZEPAM : 204 side effects (FDA XML label)
  8. CLONAZEPAM : 204 side effects (FDA XML label)
  9. CLONAZEPAM : 205 side effects (FDA XML label)
  10. CLONAZEPAM : 205 side effects (FDA XML label)