Omeprazole

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 24)
1 2 3 4 5 6 7 8 9 10
Headache def Headache def 10.9% x x x x x x x x x x
Flatulence def Flatulence def 10.3% x x x x x x x x x x
Nausea def Nausea def 6.4% x x x x x x x x x x
Abdominal pain def Abdominal pain def 5.8% x x x x x x x x x x
Gastrointestinal pain def Abdominal pain def 5.8% x x x x x x x x x x
Pain def Pain def postmarketing, 5.8% x x x x x x x x x x
Diarrhoea def Diarrhoea def 3.9% x x x x x x x x x x
Dry mouth def Dry mouth def postmarketing — 3.9% x x x x x x x x x
Dizziness def Dizziness def 2.8% x x x x x x x x x x
Vertigo def Vertigo def postmarketing, 2.8% x x x x x x x x x x
Constipation def Constipation def 2.5% x x x x x x x x x x
Injection site reaction def Injection site reaction def 1.7%
Pruritus def Pruritus def postmarketing, 1.1% x x x x x x x x x x
Abdominal mass Abdominal mass postmarketing x x x x x
Aggression def Aggression def postmarketing, rare x x x x x x x
Agranulocytosis def Agranulocytosis def postmarketing, rare x x x x x x x x
Alopecia def Alopecia def postmarketing, rare x x x x x x x x
Anaphylactic shock def Anaphylactic shock def postmarketing, rare x x x x x x x x x
Anaemia def Anaemia def postmarketing x x x x x x x x
Haemolytic anaemia def Haemolytic anaemia def postmarketing x x x x x
Angina pectoris def Angina pectoris def postmarketing x x x x x
Angioedema def Angioedema def postmarketing, rare x x x x x x x x x x
Decreased appetite Anorexia def postmarketing x x x x x x x x
Anxiety def Anxiety def postmarketing x x x x x
Arthralgia def Arthralgia def postmarketing, rare x x x x x x x x x x
Musculoskeletal discomfort Arthralgia def postmarketing, rare x x x x x x x x x x
Myalgia def postmarketing, rare x x x x x x x x
Mental disorder def Mental disorder def postmarketing x
Breast disorder def Breast disorder def postmarketing x
Bronchospasm def Bronchospasm def postmarketing, rare x x x x x
Candidiasis def Candidiasis def postmarketing, rare x x x x x x x x x x
Carcinoid tumour def Carcinoid tumour def postmarketing x x x x x
Chest pain def Chest pain def postmarketing x x x x x x x x
Retrosternal pain x x x
Confusional state def Confusional state def postmarketing, rare x x x x x x x x x x
Feeling abnormal Confusional state def postmarketing, rare x x x x x x x x x x
Malaise def postmarketing x x x x x x x x x x
Connective tissue disorder def Connective tissue disorder def postmarketing x
Dermatitis def Dermatitis def postmarketing x x x x x x x x x
Rash def postmarketing x x x x x x x x x x
Diplopia def Diplopia def postmarketing x x x x
Keratoconjunctivitis sicca def Dry eye syndrome def postmarketing x x x x
Lacrimation decreased Dry eye syndrome def postmarketing x x x x
Dysgeusia def Dysgeusia def postmarketing x x x x x x x x
Oedema def Oedema def postmarketing x x x x x x x x x x
Toxic epidermal necrolysis def Toxic epidermal necrolysis def postmarketing, rare x x x x x x x x x
Necrolysis epidermal postmarketing, rare x x x x x x x x x
Epistaxis def Epistaxis def postmarketing x x x x x x x x
Erythema multiforme def Erythema multiforme def postmarketing, rare x x x x x x x x x
Stevens-Johnson syndrome def rare
Oesophageal disorder def Oesophageal disorder def postmarketing x x x x x x x x
Rash def Rash def postmarketing x x x x x x x x x x
Eye disorder def Eye disorder def postmarketing x
Asthenia def Fatigue def postmarketing x x x x x x x x x
Weakness def postmarketing, rare x x x x x x x x
Asthenia def x x x x x x x x
Fatigue def Fatigue def postmarketing x x x x x x x x x
Body temperature increased def Body temperature increased def postmarketing, rare x x x x x x x x x x
Gastrointestinal disorder def Gastrointestinal disorder def postmarketing x
Glycosuria def Glycosuria def postmarketing x x x x x x x x
Gynaecomastia def Gynaecomastia def postmarketing, rare x x x x x x x x
Hallucination def Hallucination def postmarketing, rare x x x x x x x x
Haematuria def Haematuria def postmarketing x x x x x x x x
Hepatic encephalopathy def Hepatic encephalopathy def postmarketing x x x x x x
Hepatitis def Hepatitis def postmarketing, rare x x x x x x x x
Hyperhidrosis def Hyperhidrosis def postmarketing x x x x x x
Sweating def x x x x x
Sweating increased x x x x x
Hypersensitivity def Hypersensitivity def postmarketing x x x x x x x x
Hypoglycaemia def Hypoglycaemia def postmarketing x x x x x
Hyponatraemia def Hyponatraemia def postmarketing x x x x x x x x x x
Immune system disorder def Immune system disorder def postmarketing x
Inflammation def Inflammation def postmarketing x x x x x x x x
Intestinal functional disorder Irritable bowel syndrome def postmarketing x x x x x
Irritable bowel syndrome def Irritable bowel syndrome def postmarketing x x x x x
Irritability def Irritability def postmarketing x x x x x
Jaundice def Jaundice def postmarketing, rare x x x x x x x x
Pain in extremity def Leg pain postmarketing x x x x
Leukocytosis def Leukocytosis def postmarketing x x x x x x x x
Leukopenia def Leukopenia def postmarketing, rare x x x x x x x x
Liver disorder def Liver disorder def postmarketing, rare x x x x x x x
Hepatocellular injury Liver disorder def postmarketing, rare x x x x x x x
Foetor hepaticus Liver disorder def postmarketing, rare x x x x x x x
Mediastinal disorder def Mediastinal disorder def postmarketing x
Muscle spasms def Cramp muscle def postmarketing x x x x x x x x
Necrosis def Necrosis def postmarketing x x x x x
Neoplasm def Neoplasm def postmarketing x x x x x
Nephritis def Nephritis def postmarketing, rare x x x x x x x x
Tubulointerstitial nephritis Nephritis interstitial def postmarketing, rare x x x x x x x
Nervous system disorder def Nervous system disorder def postmarketing x x
Nervousness def Nervousness def postmarketing x x x x x x x x
Tension def Nervousness def postmarketing x x x x x x x x
Neuritis def Neuritis def postmarketing x x x x
Neuropathy peripheral def Neuritis def postmarketing x x x x
Neuropathy def postmarketing x x x x
Neuropathy peripheral def x x
Neutropenia def Neutropenia def postmarketing x x x x x
Optic atrophy def Optic atrophy def postmarketing x x x x
Optic nerve disorder def Optic nerve disorder def postmarketing x x x
Optic neuritis def Optic neuritis def postmarketing x x x x
Palpitations def Palpitations def postmarketing x x x x x
Pancreatitis def Pancreatitis def postmarketing x x x x x x x
Pancytopenia def Pancytopenia def postmarketing, rare x x x x x x x x
Paraesthesia def Paraesthesia def postmarketing x x x x x x x x x x
Petechiae def Petechiae def postmarketing x x x x x
Polyp def Polyp def postmarketing x x x x x x x x
Proteinuria def Proteinuria def postmarketing x x x x x
Protein urine present Proteinuria def postmarketing x x x x x
Purpura def Purpura def postmarketing x x x x x
Vascular purpura Purpura def postmarketing x x x x x
Pyuria def Pyuria def postmarketing x x x x x
Shock def Shock def postmarketing, rare x x x x x
Sleep disorder def Sleep disturbance postmarketing x
Sleep disorder def x x x
Stevens-Johnson syndrome def Stevens-Johnson syndrome def rare
Stomatitis def Stomatitis def postmarketing, rare x x x x x x x x
Swelling def Swelling def postmarketing x x x x x
Tachycardia def Tachycardia def postmarketing x x x x x x x x
Testicular pain def Testicular pain def postmarketing x x x x x
Thrombocytopenia def Thrombocytopenia def postmarketing, rare x x x x x x x x x x
Tinnitus def Tinnitus def postmarketing x x x x x x x x
Tremor def Tremor def postmarketing x x x x x x x x
Erythema def Erythema def postmarketing, rare x x x x x x x x x
Pollakiuria def Pollakiuria def postmarketing x x x x x x x x
Urinary tract infection def Urinary tract infection def postmarketing x x x x x
Urethral disorder def Urinary tract disorder def postmarketing x
Urinary tract disorder def Urinary tract disorder def postmarketing x
Urticaria def Urticaria def postmarketing x x x x x x x x x x
Weight increased def Weight increased def postmarketing x x x x x x x x
Gastrinoma def Zollinger-Ellison syndrome def postmarketing x x x x x
Encephalopathy def Encephalopathy def postmarketing, rare x x x x x x x x
Hepatic failure def Hepatic failure def postmarketing, rare x x x x x x x x
Agitation def Agitation def postmarketing, rare x x x x x x
Apathy def Apathy def postmarketing x x x x x x x x
Flat affect Apathy def postmarketing x x x x x x x x
Oedema peripheral def Oedema peripheral def postmarketing x x x x x x x x x x
Leg edema x x x
Hypomagnesaemia def Hypomagnesaemia def postmarketing
Muscular weakness def Muscular weakness def postmarketing, rare x x x x x x x x
Hepatic necrosis def Hepatic necrosis def postmarketing x x x x x
Dry skin def Dry skin def postmarketing x x x x x
Optic ischaemic neuropathy def Optic ischaemic neuropathy def postmarketing x x x
Anterior ischemic optic neuropathy postmarketing x x x
Malaise def Malaise def postmarketing x x x x x x x x x x
Discomfort def Malaise def postmarketing x x x x x x x x x x
Ill-defined disorder Malaise def postmarketing x x x x x x x x x x
Myalgia def Myalgia def postmarketing, rare x x x x x x x x
Polymyalgia x x x
Eye irritation Eye irritation postmarketing x x x x
Faeces discoloured Faeces discoloured postmarketing x x x x x
Oesophageal candidiasis Oesophageal candidiasis postmarketing x x x x x
Tongue atrophy Tongue atrophy postmarketing x x x x x
Hepatobiliary disease def Hepatobiliary disease def postmarketing x
Dry eye Dry eye postmarketing x x x x
Atrophy def Atrophy def postmarketing x x x x x
Gastrointestinal candidiasis Gastrointestinal candidiasis rare, postmarketing x x x
Vision blurred def Vision blurred def postmarketing x x x x x x x
Photosensitivity reaction def Photosensitivity def postmarketing, rare x x x x x x
Bradycardia def Bradycardia def postmarketing x x x x x
Blood pressure increased Blood pressure increased postmarketing x x x x x
Blood creatinine increased Serum creatinine increased postmarketing x x x x x
Creatinine increased def x
Aortic dissection def Dissecting aortic aneurysm, thoracic postmarketing x
Infestation Infestation NOS postmarketing x
Insomnia def Insomnia def postmarketing x x x x x x x x x x
Gastric polyps def Fundic gland polyp def postmarketing x x x x x
Somnolence def Somnolence def postmarketing x x x x x x x x x x
Ageusia def Ageusia def x x x
Albuminuria def Albuminuria def x x x
Hypochromic anaemia def Hypochromic anaemia def x x x
Arthritis def Arthritis def x x x
Arthritis aggravated x x x
Asthma def Asthma def x x x
Asthma aggravated x x x
Back pain def Back pain def x x x x x x x x
Conjunctivitis def Conjunctivitis def x x x
Cough def Cough def x x x x x x x x
Cystitis def Cystitis def x x x
Bladder pain def Cystitis def x x x
Cystitis noninfective def Cystitis def x x x
Dysphagia def Dysphagia def x x x
Duodenitis def Duodenitis def x x x
Dysmenorrhoea def Dysmenorrhoea def x x x
Dyspepsia def Dyspepsia def x x x x
Dyspnoea def Dyspnoea def x x x
Dysuria def Dysuria def x x x
Ear pain def Ear pain def x x x
Eructation def Eructation def x x x x
Oesophageal stenosis def Oesophageal stenosis def x x x
Varices oesophageal def Varices oesophageal def x x x
Reflux oesophagitis def Reflux oesophagitis def
Fibromyalgia def Fibromyalgia def x x x
Flushing def Flushing def x x x
Gastritis def Gastritis def x x x
Gastroenteritis def Gastroenteritis def x x x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def x x x
Glossitis def Glossitis def x
Goitre def Goitre def x x x
Haemorrhage def Haemorrhage def x x x
Haemoglobin def Haemorrhage def x x x
Hernia def Hernia def x x x
Hiccups def Hiccups def x x x
Hyperbilirubinaemia def Hyperbilirubinaemia def x x x
Hypertension def Hypertension def x x x
Hypoaesthesia def Hypoaesthesia def x x x
Influenza def Influenza def x x x x x
Arthropathy def Arthropathy def x x x
Osteoarthritis def Arthropathy def x x x
Laryngeal oedema def Laryngeal oedema def x x x
Melaena def Melaena def x x x
Menstrual disorder def Menstrual disorder def x x x
Oral disorder def Oral disorder def x x x
Hypertonia def Hypertonia def x x x
Fungal infection def Fungal infection def x x x
Nodule def Nodule def x x x
Ear infection def Otitis def x x x
Otitis media def Otitis media def x x x
Pharyngeal disorder def Pharyngeal disorder def x x x
Pharyngitis def Pharyngitis def x x x x x x
Polymyalgia rheumatica def Polymyalgia rheumatica def x x x
Polyuria def Polyuria def x x x
Urine output increased Polyuria def x x x
Anal pruritus def Anal pruritus def x x x
Pruritus genital Anal pruritus def x x x
Anorectal discomfort Anal pruritus def x x x
Anorectal disorder def Rectal disorder def x x x
Respiratory disorder def Respiratory disorder def x x
Respiratory tract infection def Respiratory tract infection def x x x x
Rhinitis def Rhinitis def x x x x x
Scotoma def Scotoma def x x x
Sinusitis def Sinusitis def x x x
Mouth ulceration def Ulcerative stomatitis x x
Thirst def Thirst def x x x
Tongue disorder Tongue disorder x x x
Tongue oedema x x x
Upper respiratory tract infection def Upper respiratory tract infection def x x x x x
Vaginal inflammation def Vaginal inflammation def x x x
Vaginal infection def Vaginal inflammation def x x x
Varicose vein def Varicose vein def x x x
Visual impairment def Visual impairment def x x x
Visual acuity reduced Visual impairment def x x x
Blindness def Visual impairment def x x x
Vitamin B12 deficiency def Vitamin B12 deficiency def x x x
Vomiting def Vomiting def x x x x x x x x x x
Weight decreased def Weight decreased def x x x
Hepatic function abnormal Hepatic function abnormal x x x
Migraine def Migraine def x x x
Migraine aggravated x x x
Application site reaction Application site reaction x x
Tongue discolouration Tongue discolouration x x
Generalised oedema Generalised oedema x x x
Fluid retention Generalised oedema x x x
Tongue oedema Tongue oedema x x x
Blood alkaline phosphatase increased def Phosphatase alkaline increased x x x
Aspartate aminotransferase increased def Aspartate aminotransferase increased def x x x x
Alanine aminotransferase increased def Alanine aminotransferase increased def x x x x
Oesophageal ulcer def Oesophageal ulcer def x x x
Tachypnoea def Tachypnoea def
Increased appetite Increased appetite x x x
Abdominal pain upper Epigastric pain x x x x
Rash erythematous Rash erythematous x x x
Lymphadenopathy def Lymphadenopathy cervical def x
Lymphadenopathy def x
Urine abnormality Urine abnormality x x x
Urine analysis abnormal Urine abnormality x x x
Depression def Depression aggravated x x x
Pain of skin def Pain of skin def
Erectile dysfunction def Erectile dysfunction def x x x
Dysplasia def Dysplasia def x x x
Genital candidiasis Genital candidiasis x x x
Abdominal distension def Enlargement abdomen def x x x
Dysaesthesia def Dysaesthesia def x x x
Chills def Rigors x x x
Blood gastrin increased Gastrin increased x x x
Serum gastrin increased x x x
Face oedema def Face oedema def x x x
Menopausal symptoms def Hot flush def x x x
Hot flush def Hot flush def x x x
Acne def Acne def x x x
Blood uric acid increased Hyperuricaemia def x x x
Hyperuricaemia def Hyperuricaemia def x x x
Gastrointestinal oedema Gastrointestinal oedema x x x
Parosmia def Parosmia def x x x
Regurgitation def Regurgitation def x x x x x
Indication Labels
Adenoma benign def x x x x x
Bacterial infection due to helicobacter pylori (H. pylori) x
Cancer in remission x
Duodenal ulcer def x x x x x x x
Erosive oesophagitis x x x x x x x x
Gastric ulcer def x x x x x x x
Gastrooesophageal reflux disease def x x x x x x x x x
Heartburn def x x x x x x x
Infection def x x x x x x x
Mastocytosis def x x x x x
Oesophagitis def x x x x x x x x x
Peptic ulcer def x
Reflux oesophagitis def x
Regurgitation def x
Systemic mastocytosis def x x x x
Ulcer def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: A02BC01, A02BC05

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. OMEPRAZOLE / APO-OMEPRAZOLE : 56 side effects (Health Canada)
  2. OMEPRAZOLE / LOSEC CAPSULES 10MG : 67 side effects (Health Canada)
  3. omeprazole / Prilosec : 111 side effects (FDA CDER)
  4. omeprazole / Prilosec : 123 side effects (FDA CDER)
  5. OMEPRAZOLE / PRILOSEC : 127 side effects (Drugs@FDA)
  6. OMEPRAZOLE MAGNESIUM : 129 side effects (FDA XML label)
  7. OMEPRAZOLE : 132 side effects (FDA XML label)
  8. ESOMEPRAZOLE MAGNESIUM : 148 side effects (FDA XML label)
  9. ESOMEPRAZOLE SODIUM / NEXIUM IV : 155 side effects (Drugs@FDA)
  10. ESOMEPRAZOLE SODIUM / NEXIUM IV : 189 side effects (Drugs@FDA)