Omeprazole

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels (show all 24)
1 2 3 4 5 6 7 8 9 10
Headache def 10.9% x x x x x x x x x x
Flatulence def 10.3% x x x x x x x x x x
Nausea def 6.4% x x x x x x x x x x
Abdominal pain def 5.8% x x x x x x x x x x
Pain def postmarketing, 5.8% x x x x x x x x x x
Diarrhoea def 3.9% x x x x x x x x x x
Dry mouth def postmarketing — 3.9% x x x x x x x x x
Dizziness def 2.8% x x x x x x x x x x
Vertigo def postmarketing, 2.8% x x x x x x x x x x
Constipation def 2.5% x x x x x x x x x x
Injection site reaction def 1.7%
Pruritus def postmarketing, 1.1% x x x x x x x x x x
Abdominal mass postmarketing x x x x x
Aggression def postmarketing, rare x x x x x x x
Agranulocytosis def postmarketing, rare x x x x x x x x x
Alopecia def postmarketing, rare x x x x x x x x x
Anaphylactic shock def postmarketing, rare x x x x x x x x x
Anaemia def postmarketing x x x x x x x
Haemolytic anaemia def postmarketing x x x x x
Angina pectoris def postmarketing x x x x x
Angioedema def postmarketing, rare x x x x x x x x x x
Anorexia def postmarketing x x x x x x x
Anxiety def postmarketing x x x x x
Arthralgia def postmarketing, rare x x x x x x x x x x
Mental disorder def postmarketing x
Breast disorder def postmarketing
Bronchospasm def postmarketing, rare x x x x x x
Candidiasis def postmarketing, rare x x x x x x x x x x
Carcinoid tumour def postmarketing x x x x x
Chest pain def postmarketing x x x x x x x
Confusional state def postmarketing, rare x x x x x x x x x x
Connective tissue disorder def postmarketing x
Dermatitis def postmarketing x x x x x x x x x
Diplopia def postmarketing x x x x
Dry eye syndrome def postmarketing x x x x
Dysgeusia def postmarketing x x x x x x x
Oedema def postmarketing x x x x x x x x x x
Toxic epidermal necrolysis def postmarketing, rare x x x x x x x x x
Epistaxis def postmarketing x x x x x x x
Erythema multiforme def postmarketing, rare x x x x x x x x x
Oesophageal disorder def postmarketing x x x x x x x
Rash def postmarketing x x x x x x x x x x
Eye disorder def postmarketing x
Fatigue def postmarketing x x x x x x x x x
Body temperature increased def postmarketing, rare x x x x x x x x x x
Gastrointestinal disorder def postmarketing x
Glycosuria def postmarketing x x x x x x x
Gynaecomastia def postmarketing, rare x x x x x x x x
Hallucination def postmarketing, rare x x x x x x x x
Haematuria def postmarketing x x x x x x x
Hepatic encephalopathy def postmarketing x x x x x
Hepatitis def postmarketing, rare x x x x x x x x x
Hyperhidrosis def postmarketing x x x x x
Hypersensitivity def postmarketing x x x x x x x
Hypoglycaemia def postmarketing x x x x x
Hyponatraemia def postmarketing x x x x x x x x x x
Immune system disorder def postmarketing x
Inflammation def postmarketing x x x x x x x
Irritable bowel syndrome def postmarketing x x x x x
Irritability def postmarketing x x x x x
Jaundice def postmarketing, rare x x x x x x x x x
Leg pain postmarketing x x x x
Leukocytosis def postmarketing x x x x x x x
Leukopenia def postmarketing, rare x x x x x x x x x
Liver disorder def postmarketing, rare x x x x x x x x
Mediastinal disorder def postmarketing
Cramp muscle def postmarketing x x x x x x x
Necrosis def postmarketing x x x x x
Neoplasm def postmarketing x x x x x
Nephritis def postmarketing, rare x x x x x x x x
Nephritis interstitial def postmarketing, rare x x x x x x x x
Nervous system disorder def postmarketing x
Nervousness def postmarketing x x x x x x x
Neuritis def postmarketing x x x x
Neutropenia def postmarketing x x x x x
Optic atrophy def postmarketing x x x x
Optic nerve disorder def postmarketing x x x
Optic neuritis def postmarketing x x x x
Palpitations def postmarketing x x x x x
Pancreatitis def postmarketing x x x x x x
Pancytopenia def postmarketing, rare x x x x x x x x x
Paraesthesia def postmarketing x x x x x x x x x x
Petechiae def postmarketing x x x x x
Polyp def postmarketing x x x x x x x
Proteinuria def postmarketing x x x x x
Purpura def postmarketing x x x x x
Pyuria def postmarketing x x x x x
Shock def postmarketing, rare x x x x x x x
Sleep disturbance postmarketing x x
Stevens-Johnson syndrome def rare
Stomatitis def postmarketing, rare x x x x x x x x x
Swelling def postmarketing x x x x x
Tachycardia def postmarketing x x x x x x x
Testicular pain def postmarketing x x x x x
Thrombocytopenia def postmarketing, rare x x x x x x x x x x
Tinnitus def postmarketing x x x x x x x
Tremor def postmarketing x x x x x x x
Erythema def postmarketing, rare x x x x x x x x x
Pollakiuria def postmarketing x x x x x x x
Urinary tract infection def postmarketing x x x x x
Urinary tract disorder def postmarketing
Urticaria def postmarketing x x x x x x x x x x
Weight increased def postmarketing x x x x x x x
Zollinger-Ellison syndrome def postmarketing x x x x x
Encephalopathy def postmarketing, rare x x x x x x x x
Hepatic failure def postmarketing, rare x x x x x x x x
Agitation def postmarketing, rare x x x x x x x
Apathy def postmarketing x x x x x x x
Oedema peripheral def postmarketing x x x x x x x x x x
Necrolysis epidermal postmarketing, rare x x x x x x x x x
Hypomagnesaemia def postmarketing
Muscular weakness def postmarketing, rare x x x x x x x x
Hepatic necrosis def postmarketing x x x x x
Dry skin def postmarketing x x x x x
Optic ischaemic neuropathy def postmarketing x x x
Malaise def postmarketing x x x x x x x x x x
Myalgia def postmarketing, rare x x x x x x x x x
Eye irritation postmarketing x x x x
Faeces discoloured postmarketing x x x x x
Oesophageal candidiasis postmarketing x x x x x
Tongue atrophy postmarketing x x x x x
Hepatobiliary disease def postmarketing x
Dry eye postmarketing x x x x
Atrophy def postmarketing x x x x x
Gastrointestinal candidiasis rare, postmarketing x x x
Vision blurred def postmarketing x x x x x x x x
Photosensitivity def postmarketing, rare x x x x x x x
Bradycardia def postmarketing x x x x x
Neuropathy def postmarketing x x x x
Blood pressure increased postmarketing x x x x x
Serum creatinine increased postmarketing x x x x x
Dissecting aortic aneurysm, thoracic postmarketing
Anterior ischemic optic neuropathy postmarketing x x x
Infestation NOS postmarketing
Insomnia def postmarketing x x x x x x x x x x
Fundic gland polyp def postmarketing x x x x x
Weakness def postmarketing, rare x x x x x x x x
Somnolence def postmarketing x x x x x x x x x x
Ageusia def x x
Albuminuria def x x
Hypochromic anaemia def x x
Arthritis def x x
Asthenia def x x x x x x x
Asthma def x x
Back pain def x x x x x x x
Conjunctivitis def x x
Cough def x x x x x x x
Cystitis def x x
Dysphagia def x x
Duodenitis def x x
Dysmenorrhoea def x x
Dyspepsia def x x x x
Dyspnoea def x x
Dysuria def x x
Ear pain def x x
Eructation def x x x x
Oesophageal stenosis def x x
Varices oesophageal def x x
Reflux oesophagitis def
Fibromyalgia def x x
Flushing def x x
Gastritis def x x
Gastroenteritis def x x
Gastrointestinal haemorrhage def x x
Glossitis def x x
Goitre def x x
Haemorrhage def x x
Hernia def x x
Hiccups def x x
Hyperbilirubinaemia def x x
Hypertension def x x
Hypoaesthesia def x x
Influenza def x x x x x
Arthropathy def x x
Laryngeal oedema def x x
Melaena def x x
Menstrual disorder def x x
Oral disorder def x x
Hypertonia def x x
Fungal infection def x x
Nodule def x x
Otitis def x x
Otitis media def x x
Neuropathy peripheral def x
Pharyngeal disorder def x x
Pharyngitis def x x x x x x x
Polymyalgia rheumatica def x x
Polyuria def x x
Anal pruritus def x x
Rectal disorder def x x
Respiratory disorder def x
Respiratory tract infection def x x x x
Rhinitis def x x x x x
Scotoma def x x
Sinusitis def x x
Ulcerative stomatitis x x
Sweating def x x x x x
Thirst def x x
Tongue disorder x x
Upper respiratory tract infection def x x x x x
Vaginal inflammation def x x
Varicose vein def x x
Visual impairment def x x
Vitamin B12 deficiency def x x
Vomiting def x x x x x x x x x x
Weight decreased def x x
Hepatic function abnormal x x
Migraine def x x
Application site reaction x
Creatinine increased def x
Tongue discolouration x x x
Generalised oedema x x
Tongue oedema x x
Retrosternal pain x x
Phosphatase alkaline increased x x
Aspartate aminotransferase increased def x x x x
Alanine aminotransferase increased def x x x x
Oesophageal ulcer def x x
Tachypnoea def
Increased appetite x x
Epigastric pain x x x x
Rash erythematous x x
Lymphadenopathy cervical def x
Urine abnormality x x
Depression aggravated x x
Leg edema x x
Arthritis aggravated x x
Migraine aggravated x x
Pain of skin def
Erectile dysfunction def x x
Dysplasia def x x
Genital candidiasis x x
Enlargement abdomen def x x
Dysaesthesia def x x
Rigors x x
Lymphadenopathy def x
Polymyalgia x x
Gastrin increased x x
Face oedema def x x
Asthma aggravated x x
Hot flush def x x
Sweating increased x x x x x
Acne def x x
Hyperuricaemia def x x
Sleep disorder def x x
Serum gastrin increased x x
Gastrointestinal oedema x x
Parosmia def x x
Regurgitation def x x x x x
Indication Labels
Adenoma benign def x x x x x
Bacterial infection due to helicobacter pylori (H. pylori) x x
Cancer in remission x
Duodenal ulcer def x x x x x x x x
Dyspepsia def x
Erosive oesophagitis x x x x x x x
Functional dyspepsia x
Gastric ulcer def x x x x x x x x
Gastritis def x
Gastrooesophageal reflux disease def x x x x x x x x x
Heartburn def x x x x x x x x
Infection def x x x x x x x x
Mastocytosis def x x x x x
Oesophagitis def x x x x x x x x x
Peptic ulcer def x x
Reflux oesophagitis def x x
Regurgitation def x x
Systemic mastocytosis def x x x x
Ulcer def x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: A02BC01, A02BC05

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. OMEPRAZOLE / APO-OMEPRAZOLE : 56 side effects (Health Canada)
  2. OMEPRAZOLE / LOSEC CAPSULES 10MG : 67 side effects (Health Canada)
  3. OMEPRAZOLE (OMEPRAZOLE MAGNESIUM) / RATIO-OMEPRAZOLE 10MG : 67 side effects (Health Canada)
  4. omeprazole / Prilosec : 111 side effects (FDA CDER)
  5. OMEPRAZOLE / PRILOSEC : 127 side effects (Drugs@FDA)
  6. OMEPRAZOLE MAGNESIUM : 129 side effects (FDA XML label)
  7. OMEPRAZOLE : 132 side effects (FDA XML label)
  8. OMEPRAZOLE : 133 side effects (FDA XML label)
  9. ESOMEPRAZOLE MAGNESIUM : 148 side effects (FDA XML label)
  10. ESOMEPRAZOLE SODIUM / NEXIUM IV : 170 side effects (Drugs@FDA)