Sumatriptan (sumatriptan succinate)

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 23)
1 2 3 4 5 6 7 8 9 10
Injection site reaction def Injection site reaction def 24% - 59% 24% x x x
Paraesthesia def Tingling sensation def 3% - 14% 3% x x x x x x x
Paraesthesia def 2% - 5% 2% x x x x x
Nausea def Nausea def 11% - 13.5% x x x x
Vomiting def Vomiting def 11% - 13.5% x x x
Dizziness def Dizziness def 0.9% - 12% 4% x x x
Syncope def x x x x
Vertigo def Vertigo def 0.9% - 12% 1% - 4% x x x x
Pain def Pain def postmarketing, 1% - 8% 1% - 4% x x x x x x x x
Stinging postmarketing x x x
Ache def x x x
Flushing def Flushing def 2% - 7% 2% x x x x
Burning sensation def Burning sensation def 0.1% - 7% 1% x x x x x x
Sensation of pressure Sensation of pressure 2% - 7% 2% x
Neck pain def Neck pain def 1% - 5% 1% x x x
Hypoaesthesia def Numbness def 2% - 5% 2% x x x x x x x
Hypoaesthesia def
Sensory loss Numbness def 2% - 5% 2% x x x x x x x
Discomfort def Discomfort def 0% - 5% 0% - 1% x x x x x x
Malaise def 1% - 3% 1% x x x
Chest pain def Chest discomfort 1% - 5% 1% x x
Chest pain def 1% - 2% x x
Chest discomfort Chest discomfort 1% - 5% 1% x x
Chest tightness 1% - 3% 1% x
Chest pressure 1% - 2% 1%
Musculoskeletal stiffness Stiffness 1% - 5% 1% x x x
Muscle stiffness x x x
Asthenia def Weakness def 1% - 5% 1% x x x x
Fatigue def 1% - 3% 1% x x x x
Somnolence def Drowsiness def 2% - 3% 2% x x x
Fatigue def Fatigue def 1% - 3% 1% x x x x
Malaise def Malaise def 1% - 3% 1% x x x
Feeling abnormal Malaise def 1% - 3% 1% x x x
Feeling strange 1% - 2% 1% x x x
Confusional state def x x x
Ill-defined disorder Malaise def 1% - 3% 1% x x x
Pain in jaw Pain in jaw 1% - 3% x x
Oropharyngeal discomfort Throat sore def 0.8% - 3% 1% x x
Oropharyngeal pain Throat sore def 0.8% - 3% 1% x x
Sedation Sedation 2% - 3% 2% x x x
Hyperhidrosis def Sweating def 1% - 2% 1% x x x
Myalgia def Myalgia def 1% - 2% 1% x x x x
Musculoskeletal discomfort Myalgia def 1% - 2% 1% x x x x
Arthralgia def x x x x
Anaphylactic shock def Anaphylactic shock def postmarketing x x x x
Anaphylactoid reaction postmarketing x x x
Anaemia def Anaemia def postmarketing x x x x
Haemolytic anaemia def Haemolytic anaemia def postmarketing x x
Angina pectoris def Angina pectoris def postmarketing x x x x
Prinzmetal angina def Prinzmetal angina def postmarketing x x x
Angioedema def Angioedema def postmarketing x x
Arrhythmia def Arrhythmia def postmarketing x x x x
Arteritis def Arteritis def postmarketing x x x
Asthma def Asthma def postmarketing x x x x
Atrial fibrillation def Atrial fibrillation def postmarketing x x
Bronchospasm def Bronchospasm def postmarketing x x x
Colitis def Colitis def postmarketing x x x x
Arteriospasm coronary def Arteriospasm coronary def postmarketing x x x x x x x x x
Cyanosis def Cyanosis def postmarketing x x x x
Cyanosis peripheral x x x x
Deafness def Deafness def postmarketing x x x
Hearing impaired def x x x x
Diplopia def Diplopia def postmarketing x x x x
Dyspnoea def Dyspnoea def postmarketing x x x
Oedema def Oedema def postmarketing x x x x
Embolism def Embolism def postmarketing x x x
Dermatitis def Rash def postmarketing x x x
Dermatitis def x x x x
Rash def Rash def postmarketing x x x
Eruption x x x
Extrapyramidal disorder def Extrapyramidal disorder def postmarketing x
Gastrointestinal disorder def Gastrointestinal disorder def postmarketing
Cardiac disorder def Cardiac disorder def postmarketing x
Haemorrhage def Haemorrhage def postmarketing x x x x
Haemoglobin def Haemorrhage def postmarketing x x x x
Hypersensitivity def Hypersensitivity def postmarketing x x x x x
Hypertrophy def Hypertrophy def postmarketing x
Hypotension def Hypotension def postmarketing x x x x
Immune system disorder def Immune system disorder def postmarketing x
Infarction def Infarction def postmarketing x x x x x x x x x
Ischaemia def Ischaemia def postmarketing x x x x x x x x x x
Renal failure acute def Renal failure acute def postmarketing x x
Dyskinesia def Movement disorder def postmarketing x
Movement disorder def Movement disorder def postmarketing x
Myocardial infarction def Myocardial infarction def postmarketing x x x x x x x x x
Acute coronary syndrome def Myocardial infarction def postmarketing x x x x x x x x x
Nervous system disorder def Nervous system disorder def postmarketing x
Nystagmus def Nystagmus def postmarketing x x x x
Optic nerve disorder def Optic nerve disorder def postmarketing x x x x
Palpitations def Palpitations def postmarketing x x x x x
Pancytopenia def Pancytopenia def postmarketing x x x
Panic reaction def Panic reaction def postmarketing x x x
Panic disorder def Panic disorder def postmarketing x x
Pruritus def Pruritus def postmarketing x x x x
Pulmonary embolism def Pulmonary embolism def postmarketing x x x
Raynaud's phenomenon def Raynaud's disease def postmarketing x x x x x
Renal failure def Renal failure def postmarketing x x x
Retinal artery occlusion def Retinal artery occlusion def postmarketing x x
Retinal vascular occlusion Retinal vascular occlusion postmarketing x
Scotoma def Scotoma def postmarketing x x x x
Convulsion def Seizures def postmarketing x
Convulsion def x x x x
Shock def Shock def postmarketing x x x
Syncope def x x x x
Cerebrovascular accident def Cerebrovascular accident def postmarketing x x x
Subarachnoid haemorrhage def Subarachnoid haemorrhage def postmarketing x x x
Swelling def Swelling def postmarketing x x x x
Tachycardia def Tachycardia def postmarketing x x x x x x x x x
Thrombocytopenia def Thrombocytopenia def postmarketing x x x
Thrombophlebitis def Thrombophlebitis def postmarketing x x x
Thrombosis def Thrombosis def postmarketing x x x x x
Erythema def Erythema def postmarketing x x x
Redness def postmarketing x
Urticaria def Urticaria def postmarketing x x x
Angiopathy def Angiopathy def postmarketing x
Vasculitis def Vasculitis def postmarketing x x x
Venous thrombosis def Venous thrombosis def postmarketing x x x x
Visual impairment def Visual impairment def postmarketing x x x x x x x x
Visual disturbance x x x x
Visual acuity reduced Visual impairment def postmarketing x x x x x x x x
Blindness def Visual impairment def postmarketing x x x x x x x x
Blindness def postmarketing x x x x x x x x
Dry mouth def Dry mouth def postmarketing x x x x x
Vasospasm def Vasospasm def postmarketing x x x x x x x x x
Akinesia Akinesia postmarketing x
Photopsia Photopsia postmarketing x x x x
Leukocytoclastic vasculitis def Allergic cutaneous angiitis def postmarketing x x x
Optic ischaemic neuropathy def Optic ischaemic neuropathy def postmarketing x x x
Colitis ischaemic def Colitis ischaemic def postmarketing x x x x
Cardiac fibrillation Cardiac fibrillation postmarketing x x x x x x x x x
Choreoathetosis Choreoathetoid movements postmarketing x
Arterial occlusive disease def Arterial occlusion def postmarketing x x x
Rectal haemorrhage def Rectal haemorrhage def postmarketing x x x
Induration def Induration def postmarketing x
Anaphylactoid reaction Anaphylactoid reaction postmarketing x x x
Photosensitivity reaction def Photosensitivity def postmarketing x x x
Akathisia def Akathisia def postmarketing x
Dystonia def Dystonia def postmarketing x x
Dystonic reaction x x
Bradycardia def Bradycardia def postmarketing x x x x
Neuropathy peripheral def Neuropathy def postmarketing x x x x
Dermatitis atopic def Cutaneous hypersensitivity def postmarketing x
Liver function test abnormal Raised liver function tests postmarketing x x
Liver function test abnormal x x x x x x
Cardiomyopathy def Cardiomyopathy def postmarketing x x x
Aphasia def Dysphasia def postmarketing x x x
Vascular occlusion def Vascular occlusion def postmarketing x
Lipohypertrophy def Lipohypertrophy def postmarketing x
Lipoatrophy Lipoatrophy postmarketing x
Death Death postmarketing x x x
Retinal vein thrombosis Retinal vein thrombosis postmarketing x x x
Temporal arteritis def Temporal arteritis def postmarketing x x
Abdominal distension def Abdominal distension def x x x x
Distention def x x x x
Aggression def Aggression def x x x x
Aneurysm def Aneurysm def x x x x x
Anxiety def Anxiety def x x x
Phobia def x x x x
Aortic aneurysm def Aortic aneurysm def x x x x x
Abdominal aortic aneurysm def x x x x
Sinus arrhythmia def Sinus arrhythmia def x x x
Arthralgia def Arthralgia def x x x x
Arthritis def Arthritis def x x x x
Arteriosclerosis def Atherosclerosis def x x x x
Back pain def Back pain def x x x
Breast cancer def Breast cancer def x x x x
Breast swelling Breast swelling x x x x
Bronchitis def Bronchitis def x x x x
Cholelithiasis def Cholelithiasis def x x x
Confusional state def Confusional state def x x x
Conjunctivitis def Conjunctivitis def x x x x
Constipation def Constipation def x x x x
Cough def Cough def x x x x
Cystitis def Cystitis def x x x x
Bladder pain def Cystitis def x x x x
Cystitis noninfective def Cystitis def x x x x
Cyst def Cyst def x x x x
Dysphagia def Dysphagia def x x x x
Dehydration def Dehydration def x x x
Depression def Depressive disorder def x x x x
Dysthymic disorder def Depressive disorder def x x x x
Diarrhoea def Diarrhoea def x x x x
Drug abuse def Drug abuse def x x x x
Dysarthria def Dysarthria def x x x
Osteoarthritis def Dysarthria def x x x
Dysgeusia def Dysgeusia def x
Dysmenorrhoea def Dysmenorrhoea def x x x
Dysuria def Dysuria def x
Ear pain def Ear pain def x x x x
Eczema def Eczema def x x x x
Endometriosis def Endometriosis def x x x x
Eructation def Eructation def x x x
Eye haemorrhage def Eye haemorrhage def x x x x
Facial pain def Facial pain def x x x
VIIth nerve paralysis Facial paralysis def x x x x
Body temperature increased def Body temperature increased def x x x x
Flatulence def Flatulence def x x x
Gastritis def Gastritis def x x x x
Gastroenteritis def Gastroenteritis def x x x x
Gastrooesophageal reflux disease def Gastrooesophageal reflux disease def x x x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def x x x x
Conversion disorder def Globus hystericus x x x
Hysteria def x x x
Hallucination def Hallucination def x x x x
Atrioventricular block def Block heart def x x x x
Haematemesis def Haematemesis def x x x x
Blood disorder def Blood disorder def x x x x
Haematoma def Haematoma def x x x x
Haematuria def Haematuria def x x x x
Hemiplegia def Hemiplegia def x x x
Hemiplegia transient x x x
Herpes virus infection def Herpes NOS def x x x x
Hiccups def Hiccups def x x x
Hunger def Hunger def x x x
Hyperaesthesia def Hyperaesthesia def x x x
Hyperglycaemia def Hyperglycaemia def x x x x
Hypertension def Hypertension def x x x x
Hypertensive episode x x x x
Hypertensive x x x x
Hypoglycaemia def Hypoglycaemia def x x x x
Hypothyroidism def Hypothyroidism def x x x x
Infection def Infection def x x x x x
Inflammation def Inflammation def x x x x
Influenza def Influenza def x x x
Intestinal obstruction def Intestinal obstruction def x x x x
Eye pruritus Eye pruritus x x
Keratitis def Keratitis def x x x x
Nephrolithiasis def Calculus of kidney def x x x
Melaena def Melaena def x x x x
Meniere's disease def Meniere's disease def x x x x
Menstrual disorder def Menstrual disorder def x x x x
Menstrual cycle abnormal x x x x
Metrorrhagia def Metrorrhagia def x x x x
Muscle spasms def Cramp muscle def x x x
Muscle rigidity def Muscle rigidity def x x x x
Muscle atrophy def Muscle atrophy def x x x x x
Myopathy def Myopathy def x x x x
Musculoskeletal pain def Musculoskeletal pain def x
Mydriasis def Mydriasis def x x x x
Neoplasm def Neoplasm def x x x x
Neuralgia def Neuralgia def x x x x
Neurosis def Neurosis def x x x x
Nodule def Nodule def x x x x
Obstruction def Obstruction def x x x x
Ear infection def Otitis def x x x x
Ear infection def x x x x
Otitis externa def Otitis externa def x x x x
Pallor def Pallor def x x x
Pancreatitis def Pancreatitis def x x x x
Peptic ulcer def Peptic ulcer def x x x
Phlebitis def Phlebitis def x x x x x
Pituitary tumour def Pituitary tumour def x x x x
Supraventricular extrasystoles def Supraventricular extrasystoles def x x x
Respiratory tract infection def Respiratory tract infection def x x x x
Rhinitis def Rhinitis def x x x x
Scleral disorder def Scleral disorder def x x x x
Seborrhoeic dermatitis def Seborrhoeic dermatitis def x x x x
Chills def Shivering def x x x
Chills def x x x
Salivary hypersecretion def Salivary hypersecretion def x x x x
Sinusitis def Sinusitis def x x x x
Skin wrinkling Skin wrinkling x x x x
Sleep disorder def Sleep disturbance x x x
Completed suicide Suicide def x x x x
Syncope def Syncope def x x x x
Loss of consciousness def Syncope def x x x x
Tetany def Tetany def x x x x
Thirst def Thirst def x x x
Tinnitus def Tinnitus def x x x x
Toothache def Toothache def x x x x
Tremor def Tremor def x x x x
Ulcer def Ulcer def x x x
Urethritis def Urethritis def x x x x
Pollakiuria def Pollakiuria def x x
Vasodilation procedure Vasodilation def x x x
Ventricular fibrillation def Ventricular fibrillation def x x x x x x x x x
Ventricular tachycardia def Ventricular tachycardia def x x x x x x x x x
Viral infection def Viral infection def x
Weight increased def Weight increased def x x x x
Weight decreased def Weight decreased def x x x x
Yawning def Yawning def x x x
Urogenital disorder Urogenital disorder
Polydipsia def Polydipsia def x x x
Monoplegia Monoplegia x x x
Agitation def Agitation def x x x x
Apathy def Apathy def x x x x
Flat affect Apathy def x x x x
Photophobia def Photophobia def x x x
Hepatic function abnormal Hepatic function abnormal x x x x x x
Lower respiratory tract infection Lower respiratory tract infection x x x x
Breast discharge def Breast discharge def x x x x
Swelling face Swelling face x x x x
Ventricular extrasystoles def Ventricular extrasystoles def x x x
Intracranial pressure increased def Intracranial pressure increased def x x x x
Myocardial ischaemia def Myocardial ischaemia def x x x x x x x x x
Eye pain def Eye pain def x x x x
Intervertebral disc disorder Intervertebral disc disorder x x x x
Oedema peripheral def Swelling of limb x x x
Diplegia Diplegia x x x
Temperature intolerance Heat intolerance x x x x
Muscle twitching def Muscle twitching def x x x x
Decreased appetite Decreased appetite x x x
Abdominal discomfort Abdominal discomfort x x x
Gastrointestinal discomfort x
Retching def Retching def x x x
Speech disorder def Speech impairment NOS x x x x
Memory impairment def Memory impairment def x x x x
Motor dysfunction Motor dysfunction x x x x
Feeling cold Feeling cold x x x
Tenderness def Tenderness def x x x x
Hypervigilance def Hypervigilance def x x x x
Euphoric mood def Euphoric mood def x x x
Eye irritation Eye irritation x x
Pulse abnormal Pulse abnormal x x x x
Galactorrhoea Galactorrhoea x x x x
Skin exfoliation Skin exfoliation x
Skin scaly x x x x
Localized exfoliation def x x
Personality change def Personality change def x x x x
Salivary gland enlargement Salivary gland swelling x x x x
Pain of skin def Skin tenderness x x x
Skin tightness Skin tightness x x x x
Glossodynia def Burning tongue x x x x
Muscle fatigue def Muscle fatigue def x
Fluid retention Fluid retention x x x x
Musculoskeletal deformity def Musculoskeletal deformity def x x x x
Deformity Deformity x x x x
Gait disturbance def Walking difficulty x x x x
Atrophy def Atrophy def x x x x x
Extrasystoles def Extrasystoles def x x x
Phobia def Phobia def x x x x
Dysaesthesia def Dysaesthesia def x x x
Lacrimation increased def Lacrimation def x x x
Lymphadenopathy def Lymphadenopathy def x x x x
Blood pressure increased Blood pressure increased x x
Hypoaesthesia oral Numbness of tongue x x x x
Coordination abnormal Coordination abnormal x x x x
Paralysis def Paralysis def x x x x
Feeling of body temperature change Feeling hot and cold x x x
Dissociation Detachment psychological x x x x
Muscle tightness Neck tightness
Muscle tightness x x
Pharyngeal haemorrhage def Pharyngeal haemorrhage def x x x x
Mass def Mass def x x x x
Gastrointestinal pain def Gastrointestinal pain def x x x x
Nerve root lesion Radiculopathy def x x x x
Radiculopathy def Radiculopathy def x x x x
Poisoning def Intoxication x x x
Substance abuse def Substance abuse def
Eye oedema Eye oedema x x x x
Phonophobia Phonophobia x x x x
Electrocardiogram change def Electrocardiogram change def x x
Cerebral ischaemia def Cerebral ischaemia def x x x x
Oral pruritus Oral pruritus x x x x
Respiratory disorder def Respiration abnormal x x x x
Respiration abnormal Respiration abnormal x x x x
Hearing impaired def Hearing impaired def x x x x
Breast neoplasm def Breast neoplasm def x x x x
Dysphonia def Voice disturbance x x x x
Rhinitis allergic def Rhinitis allergic def x x x x
Nasal inflammation Nasal inflammation x x x x
Indication Labels
Aura x x x x x x x x x
Basilar migraine x x x x x x
Cluster headache def x x x x x x x x x x
Headache def x x x x x x x x x x
Migraine def x x x x x x x x x x
Ophthalmoplegic migraine def x x x x
Premenstrual syndrome def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N02CC01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. SUMATRIPTAN SUCCINATE / IMITREX STATDOSE : 10 side effects (Drugs@FDA)
  2. sumatriptan / Imitrex : 21 side effects (FDA MedWatch)
  3. SUMATRIPTAN (SUMATRIPTAN SUCCINATE) / PHL-SUMATRIPTAN : 24 side effects (Health Canada)
  4. SUMATRIPTAN (SUMATRIPTAN SUCCINATE) / PMS-SUMATRIPTAN : 24 side effects (Health Canada)
  5. SUMATRIPTAN (SUMATRIPTAN SUCCINATE) / RIVA-SUMATRIPTAN : 44 side effects (Health Canada)
  6. SUMATRIPTAN (SUMATRIPTAN SUCCINATE) / NOVO-SUMATRIPTAN DF : 46 side effects (Health Canada)
  7. SUMATRIPTAN : 152 side effects (FDA XML label)
  8. sumatriptan : 280 side effects (FDA XML label)
  9. SUMATRIPTAN : 283 side effects (FDA XML label)
  10. SUMATRIPTAN : 294 side effects (FDA XML label)