Definition: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
Synonyms (terms occurring on more labels are shown first): serotonin syndrome, serotonergic syndrome
More information: PubMed search and possibly Wikipedia
Drugs with this side effect as MedDRA Preferred Term
|