Azilect

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.)

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4
Headache def Headache def 14% 12% x x x
Arthralgia def Arthralgia def 7% 4% x x x x
Musculoskeletal discomfort Arthralgia def 7% 4% x x x x
Dyspepsia def Dyspepsia def 7% 4% x x x x
Anxiety def Anxiety def frequent x x x
Asthenia def Asthenia def frequent x x x
Bundle branch block def Bundle branch block def frequent x x x
Cough def Cough def frequent x x x
Cough increased frequent x x x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def frequent x x x
Haematuria def Haematuria def frequent x x x
Haemorrhage def Haemorrhage def rare — frequent x x x
Haemoglobin def Haemorrhage def rare — frequent x x x
Incontinence def Incontinence def infrequent, frequent x x x
Influenza def Influenza def 5% 1% x x x x
Hypertonia def Hypertonia def frequent x x x
Tremor def Tremor def frequent x x x
Urinary incontinence def Urinary incontinence def frequent x x x
Agitation def Hyperkinesia def frequent x x x
Agitation def infrequent x x x
Hyperkinesia def Hyperkinesia def frequent x x x
Neuropathy peripheral def Neuropathy def frequent x x x
Neuritis def infrequent x x x
Gait disturbance def Gait disturbance def frequent x x x
Conjunctivitis def Conjunctivitis def 3% 1% x x x
Body temperature increased def Body temperature increased def 3% 1% x x x
Gastroenteritis def Gastroenteritis def 3% 1% x x x
Rhinitis def Rhinitis def 3% 1% x x x
Arthritis def Arthritis def 2% 1% x x x
Neck pain def Neck pain def 2% 0% x x x
Ecchymosis def Ecchymosis def 2% 0% x x x
Pain def Pain def infrequent, 2% 0% x x x x
Paraesthesia def Paraesthesia def infrequent, 2% 1% x x x
Vertigo def Vertigo def 2% 1% x x x
Malaise def Malaise def 2% 0% x x x
Discomfort def Malaise def 2% 0% x x x
Feeling abnormal Malaise def 2% 0% x x x
Confusional state def x x x
Ill-defined disorder Malaise def 2% 0% x x x
Anaemia def Anaemia def infrequent x x x
Anaemia macrocytic def Anaemia macrocytic def infrequent x x x
Aphasia def Aphasia def infrequent x x x
Apnoea def Apnoea def infrequent x x x
Blepharitis def Blepharitis def infrequent x x x
Candidiasis def Candidiasis def infrequent x x x
Vulvovaginal candidiasis def Vaginal moniliasis infrequent x x x
Vulvovaginal mycotic infection Vaginal moniliasis infrequent x x x
Colitis def Colitis def infrequent x x x
Convulsion def Convulsion def infrequent x x x
Deafness def Deafness def infrequent x x x
Delusion def Delusion def infrequent x x x
Diplopia def Diplopia def infrequent x x x
Dysarthria def Dysarthria def infrequent x x x
Osteoarthritis def Dysarthria def infrequent x x x
Arthropathy def rare, infrequent x x x
Autonomic nervous system imbalance Dysautonomia def infrequent x x x
Dysgeusia def Dysgeusia def infrequent x x x
Dysmenorrhoea def Dysmenorrhoea def infrequent x x x
Dysuria def Dysuria def infrequent x x x
Urination impaired infrequent x x x
Eczema def Eczema def infrequent x x x
Oedema def Oedema def rare, infrequent x x x
Effusion def Effusion def infrequent x x x
Oesophageal disorder def Oesophageal disorder def infrequent x x x
Oesophagitis def Oesophagitis def infrequent x x x
Eye haemorrhage def Eye haemorrhage def infrequent x x x
VIIth nerve paralysis Facial paralysis def infrequent x x x
Faecal incontinence def Faecal incontinence def infrequent x x x
Flank pain def Flank pain def infrequent x x x
Glaucoma def Glaucoma def infrequent x x x
Cardiac failure def Cardiac failure def infrequent x x x
Hemiplegia def Hemiplegia def infrequent x x x
Hypoaesthesia def Hypoaesthesia def infrequent x x x
Hypocalcaemia def Hypocalcaemia def infrequent x x x
Infarction def Infarction def infrequent x x x
Intestinal obstruction def Intestinal obstruction def infrequent x x x
Arthropathy def Arthropathy def rare, infrequent x x x
Keratitis def Keratitis def infrequent x x x
Nephrolithiasis def Calculus of kidney def infrequent x x x
Renal failure acute def Renal failure acute def infrequent x x x
Laryngospasm def Laryngospasm def infrequent x x x
Muscle atrophy def Muscle atrophy def infrequent x x x
Myocardial infarction def Myocardial infarction def infrequent x x x
Acute coronary syndrome def Myocardial infarction def infrequent x x x
Myoclonus def Myoclonus def infrequent x x x
Necrosis def Necrosis def infrequent x x x
Neuritis def Neuritis def infrequent x x x
Neurosis def Neurosis def infrequent x x x
Nocturia def Nocturia def infrequent x x x
Obstruction def Obstruction def infrequent x x x
Osteonecrosis def Osteonecrosis def infrequent x x x
Personality disorder def Personality disorder def infrequent x x x
Phlebitis def Phlebitis def infrequent x x x
Pleural disorder def Pleural disorder def infrequent x x x
Pleural effusion def Pleural effusion def infrequent x x x
Pneumothorax def Pneumothorax def infrequent x x x
Polyuria def Polyuria def infrequent x x x
Urine output increased Polyuria def infrequent x x x
Eyelid ptosis def Ptosis def infrequent x x x
Uterovaginal prolapse Ptosis def infrequent x x x
Psychotic disorder def Psychotic disorder def infrequent x x x
Emphysema def Emphysema def infrequent x x x
Renal failure def Renal failure def infrequent x x x
Retinal degeneration def Retinal degeneration def infrequent x x x
Scotoma def Scotoma def infrequent x x x
Gastric disorder def Gastric disorder def infrequent x x x
Gastric ulcer def Gastric ulcer def infrequent x x x
Stomatitis def Stomatitis def infrequent x x x
Mouth ulceration def infrequent x x x
Tachycardia def Tachycardia def infrequent x x x
Thrombophlebitis def Thrombophlebitis def infrequent x x x
Ulcer def Ulcer def infrequent x x x
Urticaria def Urticaria def infrequent x x x
Vaginal inflammation def Vaginal inflammation def infrequent x x x
Vaginal infection def Vaginal inflammation def infrequent x x x
Ventricular tachycardia def Ventricular tachycardia def infrequent x x x
Urinary retention def Urinary retention def infrequent x x x
Chills def Chills def infrequent x x x
Mood swings Mood swings infrequent x x x
Affect lability Mood swings infrequent x x x
Peroneal nerve palsy def Footdrop infrequent x x x
Mouth ulceration def Mouth ulceration def infrequent x x x
Migraine def Migraine def infrequent x x x
Scrotal oedema Scrotal oedema infrequent x x x
Tongue disorder Tongue oedema infrequent x x x
Tongue oedema Tongue oedema infrequent x x x
Mania def Manic psychosis infrequent x x x
Mania def rare, infrequent x x x
Eye pain def Eye pain def infrequent x x x
Paranoia def Paranoid reaction infrequent x x x
Paraesthesia oral Circumoral paresthesia infrequent x x x
Deep vein thrombosis def Deep thrombophlebitis infrequent x x x
Oesophageal ulcer def Oesophageal ulcer def infrequent x x x
Photosensitivity reaction def Photosensitivity reaction def infrequent x x x
Photosensitivity def infrequent x x x
Radial nerve palsy Wrist drop infrequent x x x
Atrophy def Atrophy def infrequent x x x
Dysaesthesia def Dysaesthesia def infrequent x x x
Dementia def Dementia def infrequent x x x
Coordination abnormal Coordination abnormal infrequent x x x
Paralysis def Paralysis def infrequent x x x
Face oedema def Face oedema def infrequent x x x
Sexual dysfunction Sexual dysfunction infrequent x x x
Vaginal haemorrhage def Vaginal haemorrhage def infrequent x x x
Ageusia def Ageusia def rare x x x
Amenorrhoea def Amenorrhoea def rare x x x
Anuria def Anuria def rare x x x
Arrhythmia def Arrhythmia def rare x x x
Atrioventricular block def Atrioventricular block def rare x x x
Bipolar disorder def Bipolar disorder def rare x x x
Bipolar I disorder Bipolar disorder def rare x x x
Delirium def Delirium def rare x x x
Depression def Reactive depression def rare x x x
Dermatitis def Dermatitis def rare x x x
Rash def x x x x
Dermatitis exfoliative def Dermatitis exfoliative def rare x x x
Epididymitis def Epididymitis def rare x x x
Fibrosis def Fibrosis def rare x x x
Gastritis def Gastritis def rare x x x
Gynaecomastia def Gynaecomastia def rare x x x
Haematemesis def Haematemesis def rare x x x
Hostility def Hostility def rare x x x
Libido increased def Libido increased def postmarketing x
Disturbance in sexual arousal Libido increased def postmarketing x
Libido decreased def x x x
Intestinal perforation def Intestinal perforation def rare x x x
Ischaemia def Ischaemia def rare x x x
Jaundice def Jaundice def rare x x x
Laryngeal oedema def Laryngeal oedema def rare x x x
Genital discharge Leukorrhea def rare x x x
Megacolon def Megacolon def rare x x x
Melaena def Melaena def rare x x x
Myelitis def Myelitis def rare x x x
Neuralgia def Neuralgia def rare x x x
Pathological gambling def Pathological gambling def postmarketing x
Pneumonia def Pneumonia def rare x x x
Priapism def Priapism def rare x x x
Pulmonary fibrosis def Pulmonary fibrosis def rare x x x
Purpura def Purpura def rare x x x
Vascular purpura Purpura def rare x x x
Retinal detachment def Retinal detachment def rare x x x
Retinal haemorrhage def Retinal haemorrhage def rare x x x
Strabismus def Strabismus def rare x x x
Thrombosis def Thrombosis def rare x x x
Ventricular fibrillation def Ventricular fibrillation def rare x x x
Vestibular disorder def Vestibular disorder def rare x x x
Arrhythmia supraventricular def Atrial arrhythmia def rare x x x
Stupor def Stupor def rare x x x
Depressed level of consciousness def Stupor def rare x x x
Apathy def Apathy def rare x x x
Flat affect Apathy def rare x x x
Photophobia def Photophobia def rare x x x
Atrioventricular block complete def Atrioventricular block complete def rare x x x
Large intestine perforation Large intestine perforation rare x x x
Arterial thrombosis Arterial thrombosis rare x x x
Leukoderma def Leukoderma def rare x x x
Interstitial lung disease def Interstitial pneumonia rare x x x
Cardiac fibrillation Cardiac fibrillation rare x x x
Ventricular extrasystoles def Ventricular bigeminy def rare x x x
Extrasystoles def Ventricular bigeminy def rare x x x
Atrioventricular block second degree def Atrioventricular block second degree def rare x x x
Intestinal stenosis Intestinal stenosis rare x x x
Major depression def Depressive type psychosis rare x x x
Hypersexuality Hypersexuality postmarketing x
Blindness def Blindness def rare x x x
Hydroureter def Hydroureter def rare x x x
Dissociation Detachment psychological rare x x x
Thrombocytosis def Thrombocytosis def rare x x x
Cerebral ischaemia def Cerebral ischaemia def rare x x x
Parosmia def Parosmia def rare x x x
Gastritis haemorrhagic Gastritis haemorrhagic rare x x x
Ejaculation disorder def Abnormal ejaculation rare x x x
Cerebral haemorrhage def Cerebral haemorrhage def rare x x x
Abdominal pain def Abdominal pain def x x x x
Gastrointestinal pain def Abdominal pain def x x x x
Albuminuria def Albuminuria def x x x
Alopecia def Alopecia def x x x
Amnesia def Amnesia def x x x
Angina pectoris def Angina pectoris def x x x
Decreased appetite Anorexia def x x x x
Asthma def Asthma def x x x
Ataxia def Ataxia def x x x
Bursitis def Bursitis def x x x
Neoplasm malignant def Carcinoma def x x x
Chest pain def Chest pain def x x x
Confusional state def Confusional state def x x x
Constipation def Constipation def x x x x
Libido decreased def Libido decreased def x x x
Dysphagia def Dysphagia def x x x
Diarrhoea def Diarrhoea def x x x
Dizziness def Dizziness def x x x
Syncope def x x x
Dyskinesia def Dyskinesia def x x x x
Dyspnoea def Dyspnoea def x x x
Epistaxis def Epistaxis def x x x
Rash def Rash def x x x x
Gingivitis def Gingivitis def x x x
Hallucination def Hallucination def x x x
Hernia def Hernia def x x x
Hypersensitivity def Hypersensitivity def x x x
Hypotension def Hypotension def x x x x
Orthostatic hypotension def Orthostatic hypotension def x x x x
Infection def Infection def x x x
Muscle spasms def Cramps of lower extremities x x x
Cramp muscle def x x x
Leukopenia def Leukopenia def x x x
Nausea def Nausea def x x x x
Pruritus def Pruritus def x x x
Skin ulcer def Skin ulcer def x x x
Cerebrovascular accident def Cerebrovascular accident def x x x
Hyperhidrosis def Sweating def x x x
Shock def Syncope def x x x
Syncope def Syncope def x x x
Loss of consciousness def Syncope def x x x
Tenosynovitis def Tenosynovitis def x x x
Vomiting def Vomiting def x x x x
Weight decreased def Weight decreased def x x x x
Dry mouth def Dry mouth def x x x x
Liver function test abnormal Liver function test abnormal x x x
Rash pustular def Vesiculobullous rash x x x
Dermatitis bullous def Vesiculobullous rash x x x
Abnormal dreams Abnormal dreams x x x x
Erectile dysfunction def Erectile dysfunction def x x x
Dystonia def Dystonia def x x x
Skin cancer def Skin carcinoma def x x x
Muscular weakness def Myasthenia def x x x
Somnolence def Somnolence def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N04BD02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. RASAGILINE : 16 side effects (FDA XML label)
  2. RASAGILINE MESYLATE / AZILECT : 233 side effects (Drugs@FDA)
  3. RASAGILINE (RASAGILINE MESYLATE) / AZILECT : 233 side effects (Health Canada)
  4. rasagiline : 236 side effects (FDA XML label)