Trazodone

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Sedation Sedation 3.96% - 46% 19.1% x
Somnolence def Somnolence def 3.96% - 46% 19.1% x
Drowsiness def x x x x x
Headache def Headache def 0.99% - 33.2% 27% x x x x x x
Dry mouth def Dry mouth def 25.2% 12.7% x x x x x x
Dizziness def Dizziness def 3.47% - 24.8% 12.3% x x x x x x
Syncope def postmarketing x x x x x x x
Lightheadedness x x x x
Nausea def Nausea def postmarketing, 0.99% - 20.8% 12.7% x x x x x x x
Asthenia def Fatigue def 14.9% 8.33% x x x x x x
Weakness def postmarketing x x x x x x x
Fatigue def Fatigue def 14.9% 8.33% x x x x x x
Diarrhoea def Diarrhoea def 9.41% 11.3% x x x x x x
Constipation def Constipation def 7.92% 1.96% x x x x x x
Back pain def Back pain def 5.45% 3.43% x
Pain def Pain def 5.45% 3.43% x x x x x x x
Ache def x x x x x
Vision blurred def Vision blurred def 5.45% 0% x x x x x x
Confusional state def Confusional state def 0.99% x x x x x x
Feeling abnormal Confusional state def 0.99% x x x x x x
Malaise def x x
Coordination abnormal Coordination abnormal 0.99% x x x
Gait disturbance def Gait disturbance def 0.99% x
Balance disorder Balance disorder 0.99% x
Alopecia def Alopecia def postmarketing x x x x
Anaemia def Anaemia def postmarketing x x x x x x x
Haemolytic anaemia def Haemolytic anaemia def postmarketing x x x x x x x
Aphasia def Aphasia def postmarketing x x x x
Apnoea def Apnoea def postmarketing x x x x x x x
Arrhythmia def Arrhythmia def postmarketing x x x x x x x
Ataxia def Ataxia def postmarketing x x x x x x x
Atrial fibrillation def Atrial fibrillation def postmarketing x x x x x x x
Breast feeding def Breast feeding def postmarketing x x x x
Cholestasis def Cholestasis def postmarketing x x
Diplopia def Diplopia def postmarketing x x x x x x x
Dyskinesia def Dyskinesia def postmarketing x x x x
Movements involuntary def x x x
Oedema def Oedema def postmarketing x x x x x x x
Grand mal convulsion def Grand mal convulsion def postmarketing x x x x x x x
Tonic-clonic seizures def postmarketing x x x x x x x
Oesophageal achalasia def Oesophageal achalasia def postmarketing x x x x
Dermatitis def Rash def postmarketing x x x x x x x
Rash def Rash def postmarketing x x x x x x x
Eruption x x x
Hallucination def Hallucination def postmarketing x x x x x x x
Cardiac arrest def Cardiac arrest def postmarketing x x x x x x x
Cardiac failure def Cardiac failure def postmarketing x x x x
Cardiac failure congestive def Cardiac failure congestive def postmarketing x x x x
Hirsutism def Hirsutism def postmarketing x x x x
Hyperbilirubinaemia def Hyperbilirubinaemia def postmarketing x x x x
Hyperaemia def Hyperaemia def postmarketing x x x x
Hypertrophy def Hypertrophy def postmarketing x x x x
Hypotension def Hypotension def postmarketing x x x x x x x
Orthostatic hypotension def Orthostatic hypotension def postmarketing x x x x x x x
Inappropriate antidiuretic hormone secretion def Inappropriate antidiuretic hormone secretion def postmarketing x x x x
Incontinence def Incontinence def postmarketing x x x x x x x
Infarction def Infarction def postmarketing x x x x x x x
Jaundice def Jaundice def postmarketing x x x x x x x
Leukocytosis def Leukocytosis def postmarketing x x x x
Methaemoglobinaemia def Methaemoglobinaemia def postmarketing x x x x x x x
Myocardial infarction def Myocardial infarction def postmarketing x x x x x x x
Acute coronary syndrome def Myocardial infarction def postmarketing x x x x x x x
Palpitations def Palpitations def postmarketing x x x x x x x
Paraesthesia def Paraesthesia def postmarketing x x x x x x x
Tingling sensation def x x x
Priapism def Priapism def postmarketing x x x x x x x
Pruritus def Pruritus def postmarketing x x x x x x x
Psoriasis def Psoriasis def postmarketing x x x x
Psychotic disorder def Psychotic disorder def postmarketing x x x x
Paranoia def x x x
Salivary hypersecretion def Salivation def postmarketing x x x x
Salivary hypersecretion def postmarketing x x x x x x x
Convulsion def Seizures def postmarketing x x x x x x x
Cerebrovascular accident def Cerebrovascular accident def postmarketing x x x x
Shock def Syncope def postmarketing x x x x x x x
Syncope def Syncope def postmarketing x x x x x x x
Loss of consciousness def Syncope def postmarketing x x x x x x x
Tachycardia def Tachycardia def postmarketing x x x x x x x
Torsade de pointes def Torsade de pointes def postmarketing x
Urinary incontinence def Urinary incontinence def postmarketing x x x x
Urticaria def Urticaria def postmarketing x x x x
Vasodilation procedure Vasodilation def postmarketing x x x x
Ventricular tachycardia def Ventricular tachycardia def postmarketing x x x x x x x
Vertigo def Vertigo def postmarketing x x x x x x x
Vomiting def Vomiting def postmarketing x x x x x x x
Urinary retention def Urinary retention def postmarketing x x x x x x x
Chills def Chills def postmarketing x x x x
Stupor def Stupor def postmarketing x x x x
Depressed level of consciousness def Stupor def postmarketing x x x x
Blood amylase increased Amylase increased postmarketing x x x x
Ventricular extrasystoles def Ventricular extrasystoles def postmarketing x x x x x x x
Paranoia def Paranoid reaction postmarketing x x x x
Paranoia def x x x
Electrocardiogram QT prolonged def Electrocardiogram QT prolonged def postmarketing x
Cardiac fibrillation Cardiac fibrillation postmarketing x x x x x x x
Extrapyramidal disorder def Extrapyramidal symptoms postmarketing x x x x
Abnormal dreams Abnormal dreams postmarketing x x x x
Vivid dreams x x
Nail discolouration def Leukonychia postmarketing x x x x
Death Found dead (cause undetermined) postmarketing x x x x
Death postmarketing x x x x
Bradycardia def Bradycardia def postmarketing x x x x x x x
Tardive dyskinesia def Tardive dyskinesia def postmarketing x x x x
Blood antidiuretic hormone abnormal def Antidiuretic hormone abnormality postmarketing x x x x
Antidiuretic hormone abnormality Antidiuretic hormone abnormality postmarketing x x x x
Insomnia def Insomnia def postmarketing x x x x x x x
Breast enlargement Breast enlargement postmarketing x x x x
Abdominal pain def Abdominal pain def x
Gastrointestinal pain def Abdominal pain def x
Amnesia def Amnesia def x
Anger def Anger def x x x x x
Decreased appetite Anorexia def x x x
Decreased appetite x x
Arthralgia def Arthralgia def x x x
Musculoskeletal discomfort Arthralgia def x x x
Myalgia def x
Mental disorder def Mental disorder def x
Chest pain def Chest pain def x x x x x x
Connective tissue disorder def Connective tissue disorder def x
Sudden death def Sudden death def x
Libido decreased def Libido decreased def x x x
Disturbance in sexual arousal Libido decreased def x x x
Libido increased def x x x x x x
Delusion def Delusion def x x x x x x
Dysgeusia def Dysgeusia def x
Taste peculiar x x x
Dyspnoea def Dyspnoea def x x x x x x
Oesophagitis def Oesophagitis def x
Reflux oesophagitis def Reflux oesophagitis def x
Eye disorder def Eye disorder def x
Body temperature increased def Body temperature increased def x x x
Flatulence def Flatulence def x x x
Flushing def Flushing def x
Gastrooesophageal reflux disease def Gastrooesophageal reflux disease def x
Gastrointestinal disorder def Gastrointestinal disorder def x
Haematuria def Haematuria def x x x x x x
Haemorrhage def Haemorrhage def x
Haemoglobin def Haemorrhage def x
Hostility def Hostility def x x x x x
Hyperhidrosis def Hyperhidrosis def x
Sweating def x x x x x x
Hypersensitivity def Hypersensitivity def x x x x
Hypertension def Hypertension def x x x x x
Hypoaesthesia def Hypoaesthesia def x
Numbness def x x x x x x
Hyponatraemia def Hyponatraemia def x
Immune system disorder def Immune system disorder def x
Libido increased def Libido increased def x x x x x x
Eye pruritus Eye pruritus x x x
Jaundice cholestatic def Jaundice cholestatic def x x x
Lethargy def Lethargy def x x x
Mediastinal disorder def Mediastinal disorder def x
Miosis def Miosis def x x x
Musculoskeletal pain def Musculoskeletal pain def x x
Nasal congestion def Nasal congestion def x x x
Nervous system disorder def Nervous system disorder def x
Nervousness def Nervousness def x x x x x
Tension def Nervousness def x x x x x
Tension def x x x
Neuroleptic malignant syndrome def Neuroleptic malignant syndrome def x
Night sweats def Night sweats def x
Nightmare def Nightmare def x x x x x
Sensory loss Numbness def x x x x x x
Orgasm abnormal def Orgasm abnormal def x
Speech disorder def Speech disorder def x
Speech impairment NOS x x x x x x
Gastric disorder def Gastric disorder def x x
Completed suicide Suicide def x
Tinnitus def Tinnitus def x x x x x x
Tremor def Tremor def x x x x x x
Pollakiuria def Pollakiuria def x x x x x x
Micturition urgency def x
Urethral disorder def Urinary tract disorder def x
Urinary tract disorder def Urinary tract disorder def x
Angiopathy def Angiopathy def x
Vasculitis def Vasculitis def x x x
Weight increased def Weight increased def x x x x x
Weight decreased def Weight decreased def x x
Micturition urgency def Micturition urgency def x
Sinus bradycardia def Sinus bradycardia def x x x
Photophobia def Photophobia def x
Migraine def Migraine def x
Eye pain def Eye pain def x
Sinus congestion Sinus congestion x x
Menstruation irregular def Menstruation irregular def x x x
Photosensitivity reaction def Photosensitivity reaction def x
Photosensitivity def x x x x
Musculoskeletal stiffness Muscle stiffness x x x
Stiffness x x x
Malaise def Malaise def x x
Discomfort def Malaise def x x
Discomfort def x x x
Ill-defined disorder Malaise def x x
Myalgia def Myalgia def x
Muscle twitching def Muscle twitching def x x x x x x x
Increased appetite Increased appetite x x x x x x
Bladder pain def Bladder pain def x
Disorientation Disorientation x x x x x x
Agitation def Excitement x x x x x
Hyperkinesia def x
Memory impairment def Memory impairment def x x x x x x
Dysarthria def Slurred speech x x x
Ocular hyperaemia Eye redness def x x
Hypomania def Hypomania def x x x x x x
Erectile dysfunction def Erectile dysfunction def x x x x
Dry eye Dry eye x
Akathisia def Akathisia def x x x x x x
Cold sweat Sticky skin x x
Sticky skin Sticky skin x x
Dystonia def Dystonia def x x x
Retrograde ejaculation def Retrograde ejaculation def x x x x x x
Hyperkinesia def Hyperkinesia def x
Visual impairment def Visual disturbance x
Surgery def Surgical intervention x x x
Sexual dysfunction Sexual dysfunction x
Acne def Acne def x
Aortic dissection def Dissecting aortic aneurysm, thoracic x
Haemorrhagic disorder def Hemorrhage abnormal x
Abdominal discomfort Gastrointestinal discomfort x x x
Deafness def Hearing impaired def x
Hearing impaired def Hearing impaired def x
Leukocytoclastic vasculitis def Leukocytoclastic vasculitis def x
Indication Labels
Agitation def x x x
Anxiety def x x x
Bradypsychic response x x x
Cerebration impaired def x x x
Decreased interest x x x
Depressive disorder def x x x x x x x
Depressive episode x x x
Dysphoria x x x
Fatigability x x x
Feeling guilty def x x x
Major depression def x
Major depressive disorder, single episode x x x
Sickness x x x x x x
Suicidal ideation def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Codes: A06AC07, N06AX05

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. TRAZODONE HYDROCHLORIDE / TRAZOREL : 97 side effects (Health Canada)
  2. TRAZODONE HYDROCHLORIDE / RATIO TRAZODONE : 98 side effects (Health Canada)
  3. TRAZODONE HYDROCHLORIDE / DESYREL TAB 50MG : 99 side effects (Health Canada)
  4. TRAZODONE : 89 side effects (FDA XML label)
  5. TRAZODONE : 123 side effects (FDA XML label)
  6. Trazodone : 124 side effects (FDA XML label)
  7. Trazodone : 139 side effects (FDA XML label)