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Amitriptyline

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N06AA09

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Arthritis Arthritis postmarketing x x x x x x x x x x x
Body temperature increased Body temperature increased postmarketing x x x x x x x x x
Muscle rigidity Muscle rigidity postmarketing x x x x x x x x x
Neuroleptic malignant syndrome Neuroleptic malignant syndrome postmarketing x x x x x x x x x
Tachycardia Tachycardia postmarketing x x x x x x x x x x x
Tremor Tremor postmarketing x x x x x x x x x x x
Hepatic failure Hepatic failure postmarketing x x x x x x x x x
Antinuclear antibody positive Antinuclear antibody positive postmarketing x x x x x x x x x x x
Serotonin syndrome Serotonin syndrome postmarketing x x x x x x x x x x
Hyperhidrosis Sweating increased postmarketing x x x x x x x x x
Mental status changes Mental status changes postmarketing x x x x x x x x x
Cardiomyopathy Cardiomyopathy postmarketing x x x x
Lupus-like syndrome Lupus-like syndrome postmarketing x x x x x x x x x x x
Ageusia Ageusia postmarketing x x x x x x x x x
Agranulocytosis Agranulocytosis x x x x x x x x x
Alopecia Alopecia x x x x x x x x x
Decreased appetite Anorexia x x x x x x x x x
Anxiety Anxiety x x x x x x x x x
Arrhythmia Arrhythmia x x x x x x x x
Asthenia Asthenia x x x x x x x x
Fatigue x x x x x x x x x
Ataxia Ataxia x x x x x x x x x
Bundle branch block Bundle branch block x
Coma Coma x x x x x x x x x
Confusional state Confusional state x x x x x x x x x
Feeling abnormal Confusional state x x x x x x x x x
Malaise x x x x x x x x x x x
Constipation Constipation x x x x x x x x x
Libido decreased Libido decreased x x x x x x x x x
Disturbance in sexual arousal Libido decreased x x x x x x x x x
Delusion Delusion x x x x x x x x x
Diarrhoea Diarrhoea x x x x x x x x x
Dizziness Dizziness x x x x x x x x x
Syncope x x x x x x x x x
Somnolence Drowsiness x x x x x x x x x
Dysarthria Dysarthria x x x x x x x x x
Osteoarthritis Dysarthria x x x x x x x x x
Oedema Oedema x x x x x x x x x
Eosinophilia Eosinophilia x x x x x x x x x
Dermatitis Rash x x x x x x x x x
Rash Rash x x x x x x x x x
Fatigue Fatigue x x x x x x x x x
Gynaecomastia Gynaecomastia x x x x x x x x x
Hallucination Hallucination x x x x x x x x x
Headache Headache x x x x x x x x x x x
Atrioventricular block Block heart x x x x x x x x x
Hepatitis Hepatitis x x x x x x x x x
Hypertension Hypertension x x x x x x x x x
Hypotension Hypotension x x x x x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion x x x x x x x x x
Irritability Irritability x x x x x x x x x x x
Jaundice Jaundice x x x x x x x x x
Leukopenia Leukopenia x x x x x x x x x
Mydriasis Mydriasis x x x x x x x x x
Myocardial infarction Myocardial infarction x x x x x x x x x
Acute coronary syndrome Myocardial infarction x x x x x x x x x
Nausea Nausea x x x x x x x x x x x
Nightmare Nightmare x x x x x x x x x
Hypoaesthesia Numbness x x x x x x x x x
Sensory loss Numbness x x x x x x x x x
Palpitations Palpitations x x x x x x x x x
Ileus paralytic Ileus paralytic x x x x x x x x x
Neuropathy peripheral Neuropathy peripheral x x x x x x x x x
Pruritus Pruritus x
Purpura Purpura x x x x x x x x x
Vascular purpura Purpura x x x x x x x x x
Convulsion Convulsion x x x x x x x x x
Sleep disorder Sleep disturbance x x x x x x x x x x x
Stomatitis Stomatitis x x x x x x x x x
Cerebrovascular accident Cerebrovascular accident x x x x x x x x x
Shock Syncope x x x x x x x x x
Syncope Syncope x x x x x x x x x
Loss of consciousness Syncope x x x x x x x x x
Thrombocytopenia Thrombocytopenia x x x x x x x x x
Tinnitus Tinnitus x x x x x x x x x
Torsade de pointes Torsade de pointes x
Pollakiuria Pollakiuria x x x x x x x x x
Urticaria Urticaria x x x x x x x x x
Ventricular fibrillation Ventricular fibrillation x
Ventricular tachycardia Ventricular tachycardia x
Vomiting Vomiting x x x x x x x x x
Weight increased Weight increased x x x x x x x x x
Dry mouth Dry mouth x x x x x x x x x
Urinary retention Urinary retention x x x x x x x x x
Agitation Agitation x x x x x x x x x x x
Excitement x x x x x x x x x
Drug withdrawal syndrome Withdrawal symptom x x x x x x x x x x
Pancytopenia Bone marrow depression x x x x x x x x x
Accommodation disorder Accommodation disorder x x x x x x x x x
Dyspepsia Epigastric distress x x x x x x x x x
Malaise Malaise x x x x x x x x x x x
Discomfort Malaise x x x x x x x x x x x
Ill-defined disorder Malaise x x x x x x x x x x x
Disorientation Disorientation x x x x x x x x
Extrapyramidal disorder Extrapyramidal symptoms x x x x x x x x x
Intraocular pressure increased Intraocular pressure increased x x x x
Disturbance in attention Cerebration impaired x x x x x x x x x
Mental disability Cerebration impaired x x x x x x x x x
Dysgeusia Taste peculiar x x x x x x x x x
Tongue discolouration Black hairy tongue x x x x x x x x x
Galactorrhoea Galactorrhoea x x x x x x x x x
Paraesthesia Paresthesia of limbs x x x x x x x x
Tingling sensation x x x x x x x x x
Hypomania Hypomania x x x x x x x x x x x
Erectile dysfunction Erectile dysfunction x x x x x x x x x
Conduction disorder Conduction disorder x
Mania Mania x x x x x x x x x x x
Vision blurred Vision blurred x x x x x x x x x
Hyperpyrexia Hyperpyrexia x x x x x x x x x
Dyskinesia Abnormal involuntary movements x x x x x x x x
Parotid gland enlargement Parotid swelling x x x x x x x x x
Electrocardiogram QRS complex QRS complex x
Coordination abnormal Coordination abnormal x x x x x x x x x
Tardive dyskinesia Tardive dyskinesia x x x x x x x x x
Electrocardiogram QT prolonged Electrocardiogram QT corrected interval prolonged x
Insomnia Insomnia x x x x x x x x x
Breast enlargement Breast enlargement x x x x x x x x x
Testicular swelling Testicular swelling x x x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

AMITRIPTYLINE

Side effects:22
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:23
Source:FDA Structured Product Label

amitriptyline hydrochloride / Endep

Side effects:86
Source:medicines.org.au

AMITRIPTYLINE

Side effects:91
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:93
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:94
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:94
Source:FDA Structured Product Label

Amitriptyline

Side effects:95
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:96
Source:FDA Structured Product Label

AMITRIPTYLINE

Side effects:96
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
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    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label