Amitriptyline

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Ageusia def postmarketing x x x x x x x x
Arthritis def postmarketing x x x x x x x x
Body temperature increased def postmarketing x x x x x x x x
Muscle rigidity def postmarketing x x x x x x x x
Neuroleptic malignant syndrome def postmarketing x x x x x x x x
Tachycardia def postmarketing x x x x x x x x
Tremor def postmarketing x x x x x x x x
Hepatic failure def postmarketing x x x x x x x x
Antinuclear antibody positive def postmarketing x x x x x x x x
Lupus erythematosus def postmarketing x x x x x x x x
Sweating increased postmarketing x x x x x x x x
Mental status changes postmarketing x x x x x x x x
Cardiomyopathy def postmarketing x x x x x
Malignant syndrome NOS postmarketing x x x x x x x x
Agranulocytosis def x x x x x x
Alopecia def x x x x x x
Anorexia def x x x x x x
Anxiety def x x x x x x
Arrhythmia def x x x x x x
Ataxia def x x x x x x
Coma def x x x x x x
Confusional state def x x x x x x
Constipation def x x x x x x
Libido decreased def x x x x x x
Delusion def x x x x x x
Diarrhoea def x x x x x x
Dizziness def x x x x x x
Drowsiness def x x x x x x
Dysarthria def x x x x x x
Dyskinesia def x x x x x x
Oedema def x x x x x x
Eosinophilia def x x x x x x
Rash def x x x x x x
Fatigue def x x x x x x
Gynaecomastia def x x x x x x
Hallucination def x x x x x
Headache def x x x x x x x x
Block heart def x x x x x x
Hepatitis def x x x x x x
Hypertension def x x x x x x
Hypertrophy def x x x x x x
Hypotension def x x x x x x
Orthostatic hypotension def x x x x x x
Inappropriate antidiuretic hormone secretion def x x x x x x
Infarction def x x x x x x
Irritability def x x x x x x x x
Jaundice def x x x x x x
Leukopenia def x x x x x x
Mydriasis def x x x x x x
Myocardial infarction def x x x x x x
Nausea def x x x x x x x x
Nightmare def x x x x x x
Numbness def x x x x x x
Palpitations def x x x x x x
Ileus paralytic def x x x x x x
Paraesthesia def x x x x x x
Neuropathy peripheral def x x x x x x
Purpura def x x x x x x
Seizures def x x x x x x
Sleep disturbance x x x x x x x x
Stomatitis def x x x x x x
Cerebrovascular accident def x x x x x x
Sweating def x x x x x x
Swelling def x x x x x x
Syncope def x x x x x x
Thrombocytopenia def x x x x x x
Tinnitus def x x x x x x
Pollakiuria def x x x x x
Urticaria def x x x x x x
Vomiting def x x x x x x
Weight increased def x x x x x x
Dry mouth def x x x x x x
Urinary retention def x x x x x x
Addiction def x x x x x x x x
Agitation def x x x x x x x x
Bone marrow depression def x x x x x x
Epigastric distress x x x x x x
Malaise def x x x x x x x x
Disorientation x x x x x x
Excitement x x x x x x
Extrapyramidal symptoms x x x x x x
Intraocular pressure increased x
Cerebration impaired def x x x x x x
Taste peculiar x x x x x x
Black hairy tongue x x x x x x
Galactorrhoea x x x x x x
Hypomania def x x x x x x x x
Erectile dysfunction def x x x x x x
Mania def x x x x x x x x
Vision blurred def x x x x x x
Hyperpyrexia x x x x x x
Abnormal involuntary movements def x x x x x x
Parotid swelling x x x x x x
Movements involuntary def x x x x x x
Neuropathy def x x x x x x
Coordination abnormal x x x x x x
Face oedema def x x x x x
Cutaneous hypersensitivity def x
Tardive dyskinesia def x x x x x x
Insomnia def x x x x x x
Ileus def x x x x x x
Weakness def x x x x x x
Breast enlargement x x x x x x
Tingling sensation def x x x x x x
Testicular swelling x x x x x x
Indication Labels
Depressive symptom x x x x x x x
Endogenous depression def x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N06AA09

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. AMITRIPTYLINE : 22 side effects (FDA XML label)
  2. AMITRIPTYLINE : 23 side effects (FDA XML label)
  3. amitriptyline hydrochloride / Elavil : 100 side effects (FDA MedWatch)
  4. AMITRIPTYLINE : 102 side effects (FDA XML label)
  5. AMITRIPTYLINE : 102 side effects (FDA XML label)
  6. AMITRIPTYLINE : 103 side effects (FDA XML label)
  7. Amitriptyline : 103 side effects (FDA XML label)
  8. AMITRIPTYLINE : 105 side effects (FDA XML label)