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Sibutramine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: A08AA10

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Anaphylactic shock Anaphylactic shock postmarketing x x
Anaphylactoid reaction x
Angioedema Angioedema postmarketing x x
Hypersensitivity Hypersensitivity postmarketing x x
Completed suicide Suicide postmarketing x
Urticaria Urticaria postmarketing x x
Rash Eruption postmarketing x x
Rash x x
Suicidal ideation Suicidal ideation postmarketing x
Abdominal pain Abdominal pain x x
Gastrointestinal pain Abdominal pain x x
Abscess Abscess x
Albuminuria Albuminuria x
Alopecia Alopecia x x
Amblyopia Amblyopia x x
Amenorrhoea Amenorrhoea x
Amnesia Amnesia x x
Short-term memory loss x
Anaemia Anaemia x x
Anger Anger x
Angina pectoris Angina pectoris x x
Decreased appetite Anorexia x x
Anxiety Anxiety x x
Apnoea Apnoea x
Arrhythmia Arrhythmia x
Arthralgia Arthralgia x x
Musculoskeletal discomfort Arthralgia x x
Myalgia x
Arthritis Arthritis x x
Rheumatoid arthritis x
Rheumatoid arthritis Rheumatoid arthritis x
Asthenia Asthenia x x
Asthma Asthma x
Ataxia Ataxia x
Atrial fibrillation Atrial fibrillation x x
Back pain Back pain x x
Blister Blister x
Dermatitis bullous Blister x
Bone disorder Bone disorder x
Brain neoplasm Brain neoplasm x x
Bronchitis Bronchitis x x
Bundle branch block Bundle branch block x
Bursitis Bursitis x x
Neoplasm malignant Carcinoma x
Cardiovascular disorder Cardiovascular disorder x
Cellulitis Cellulitis x
Transient ischaemic attack Transient ischaemic attack x
Neck pain Neck pain x x
Cheilitis Cheilitis x
Chest pain Chest pain x x
Retrosternal pain x
Cholecystitis Cholecystitis x
Cholelithiasis Cholelithiasis x x
Colitis Colitis x
Infection Infection x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Malaise x
Conjunctivitis Conjunctivitis x
Constipation Constipation x x
Contusion Contusion x x
Cough Cough x
Cough increased x
Cystitis Cystitis x
Bladder pain Cystitis x
Cystitis noninfective Cystitis x
Libido decreased Libido decreased x x
Disturbance in sexual arousal Libido decreased x x
Libido increased x x
Dysphagia Dysphagia x
Dehydration Dehydration x
Delusion Delusion x
Dental caries Dental caries x
Depression Depression x x
Depression aggravated x
Dermatitis Dermatitis x x
Rash x x
Dermatitis contact Dermatitis contact x
Diabetes mellitus Diabetes mellitus x
Diarrhoea Diarrhoea x x
Dizziness Dizziness x x
Syncope x x
Duodenal ulcer Duodenal ulcer x
Dysgeusia Dysgeusia x x
Dysmenorrhoea Dysmenorrhoea x x
Dyspepsia Dyspepsia x x
Dyspnoea Dyspnoea x x
Dysuria Dysuria x
Ear disorder Ear disorder x x
Ear pain Ear pain x x
Ecchymosis Ecchymosis x x
Eczema Eczema x
Oedema Oedema x
Enteritis Enteritis x
Eosinophilia Eosinophilia x
Epididymitis Epididymitis x
Epilepsy Epilepsy x x
Epistaxis Epistaxis x x
Eructation Eructation x x
Oesophagitis Oesophagitis x
Eye disorder Eye disorder x
VIIth nerve paralysis Facial paralysis x
Hepatic steatosis Liver fatty x
Body temperature increased Body temperature increased x x
Flatulence Flatulence x x
Furuncle Furunculosis x
Gastritis Gastritis x x
Gastroenteritis Gastroenteritis x x
Gastrointestinal disorder Gastrointestinal disorder x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x
Gingivitis Gingivitis x
Glaucoma Glaucoma x
Glomerulonephritis membranoproliferative Glomerulonephritis membranoproliferative x
Glossitis Glossitis x
Goitre Goitre x x
Gout Gout x
Hair disorder Hair disorder x
Breath odour Breath odour x
Headache Headache x x
Cardiac arrest Cardiac arrest x
Cardiac failure congestive Cardiac failure congestive x
Haematuria Haematuria x x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Haemorrhoids Haemorrhoids x
Hernia Hernia x
Herpes simplex Herpes simplex x x
Herpes zoster Herpes zoster x
Hostility Hostility x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hypercholesterolaemia Hypercholesterolaemia x
Hyperglycaemia Hyperglycaemia x x
Hyperkalaemia Hyperkalaemia x
Hyperlipidaemia Hyperlipidaemia x
Hypertension Hypertension x x
Malignant hypertension Malignant hypertension x
Hyperthyroidism Hyperthyroidism x x
Hyperventilation Hyperventilation x
Hypoaesthesia Hypoaesthesia x x
Hypoglycaemia Hypoglycaemia x x
Hypokalaemia Hypokalaemia x
Hypotension Hypotension x
Orthostatic hypotension Orthostatic hypotension x
Hypothyroidism Hypothyroidism x
Immune system disorder Immune system disorder x
Libido increased Libido increased x x
Inflammation Inflammation x
Influenza Influenza x x
Intestinal obstruction Intestinal obstruction x
Iritis Iritis x
Arthropathy Arthropathy x x
Osteoarthritis Arthropathy x x
Lacrimal disorder Lacrimal disorder x
Lacrimal structural disorder Lacrimal disorder x
Laryngitis Laryngitis x x
Muscle spasms Cramps of lower extremities x x
Leukocytosis Leukocytosis x
Leukopenia Leukopenia x x
Lung disorder Lung disorder x
Lymphocytosis Lymphocytosis x
Menstrual disorder Menstrual disorder x x
Metrorrhagia Metrorrhagia x x
Hypertonia Hypertonia x x
Myopathy Myopathy x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Myoclonus Myoclonus x
Nail disorder Nail disorder x
Nasal congestion Nasal congestion x
Nausea Nausea x x
Neoplasm Neoplasm x
Tubulointerstitial nephritis Nephritis interstitial x x
Acute interstitial nephritis x x
Nervousness Nervousness x x
Tension Nervousness x x
Neuralgia Neuralgia x
Neuritis Neuritis x
Neuropathy peripheral Neuritis x
Neurosis Neurosis x
Nightmare Nightmare x
Osteoporosis Osteoporosis x
Otitis externa Otitis externa x x
Otitis media Otitis media x x
Pain Pain x
Pain in extremity Pain in extremity x
Palpitations Palpitations x x
Paraesthesia Paraesthesia x x
Pelvic pain Pelvic pain x
Tooth abscess Abscess periodontal x
Personality disorder Personality disorder x
Petechiae Petechiae x
Pharyngitis Pharyngitis x x
Phlebitis Phlebitis x
Pneumonia Pneumonia x
Supraventricular extrasystoles Supraventricular extrasystoles x
Pruritus Pruritus x x
Psoriasis Psoriasis x
Psychotic disorder Psychotic disorder x
Psychotic episode x
Purpura Purpura x
Vascular purpura Purpura x
Henoch-Schonlein purpura Henoch-Schonlein purpura x
Anorectal disorder Rectal disorder x x
Retinal disorder Retinal disorder x
Rhinitis Rhinitis x x
Convulsion Convulsion x x
Sepsis Septicemia x
Shock Shock x
Syncope x x
Salivary hypersecretion Salivary hypersecretion x
Sinusitis Sinusitis x x
Skin disorder Skin disorder x
Neoplasm skin Neoplasm skin x
Skin mass Skin nodule x
Skin ulcer Skin ulcer x
Speech disorder Speech disorder x
Gastric ulcer Gastric ulcer x x
Stomatitis Stomatitis x
Mouth ulceration x x
Cerebrovascular accident Cerebrovascular accident x x
Hyperhidrosis Sweating x
Syncope Syncope x x
Loss of consciousness Syncope x x
Tachycardia Tachycardia x x
Supraventricular tachycardia Supraventricular tachycardia x
Tenosynovitis Tenosynovitis x x
Thirst Thirst x x
Thrombocytopenia Thrombocytopenia x x
Thyroid disorder Thyroid disorder x
Tinnitus Tinnitus x x
Tongue disorder Tongue disorder x
Tongue oedema x x
Tooth disorder Tooth disorder x
Torsade de pointes Torsade de pointes x
Torticollis Torticollis x
Tourette's disorder Tourette's disorder x
Tremor Tremor x x
Pollakiuria Pollakiuria x
Urinary incontinence Urinary incontinence x
Urinary tract infection Urinary tract infection x x
Varicose vein Varicose vein x
Angiopathy Angiopathy x
Vascular headache Vascular headache x
Vasodilation procedure Vasodilation x x
Ventricular fibrillation Ventricular fibrillation x
Ventricular tachycardia Ventricular tachycardia x
Vertigo Vertigo x x
Vestibular disorder Vestibular disorder x
Vomiting Vomiting x x
Weight increased Weight increased x
Dry mouth Dry mouth x x
Yawning Yawning x
Urinary retention Urinary retention x
Peripheral vascular disorder Peripheral vascular disorder x
Chills Chills x
Agitation Agitation x x
Hyperkinesia x
Apathy Apathy x
Flat affect Apathy x
Mood swings Mood swings x
Affect lability Mood swings x
Rash pustular Rash pustular x
Oedema peripheral Oedema peripheral x x
Monocytosis Monocytosis x
Cataract Cataract x
Hepatic function abnormal Hepatic function abnormal x
Mouth ulceration Mouth ulceration x x
Migraine Migraine x x
Alcohol intolerance Alcohol intolerance x
Hormone level abnormal Hormone level abnormal x
Blood urea increased Blood urea increased x
Blood creatinine increased Creatinine increased x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Tongue oedema Tongue oedema x x
Ventricular extrasystoles Ventricular extrasystoles x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Skin hypertrophy Skin hypertrophy x
Injury Accidental injury x
Liver function test abnormal Liver function test abnormal x x
Mania Manic psychosis x
Bone pain Bone pain x
Eye pain Eye pain x x
Paraesthesia oral Circumoral paresthesia x
Blood alkaline phosphatase increased Phosphatase alkaline increased x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x
Alanine aminotransferase increased Alanine aminotransferase increased x
Dry skin Dry skin x
Abnormal faeces Abnormal faeces x
Iron deficiency anaemia Iron deficiency anaemia x
Malnutrition Malnutrition x
Hangover Hangover x
Rash macular Rash macular x
Rash vesicular Rash vesicular x
Malaise Malaise x
Discomfort Malaise x
Ill-defined disorder Malaise x
Myalgia Myalgia x
Muscle twitching Muscle twitching x x
Chest discomfort Chest tightness x
Chest pressure x
Increased appetite Increased appetite x x
Thinking abnormal Thinking abnormal x x
Mental disability Thinking abnormal x x
Cerebration impaired x
Abnormal dreams Abnormal dreams x
Intraocular pressure increased Intraocular pressure increased x
Euphoric mood Euphoric mood x
Disturbance in attention Cerebration impaired x
Therapeutic response unexpected Unexpected therapeutic effect x
Erectile dysfunction Erectile dysfunction x x
Rectal haemorrhage Rectal haemorrhage x
Nephritis Acute nephritis x
Nephritic syndrome Acute nephritis x
Major depression Psychotic depression x
Dry eye Dry eye x x
Anaphylactoid reaction Anaphylactoid reaction x
Vision blurred Vision blurred x
Photosensitivity reaction Photosensitivity x x
Abdominal distension Enlargement abdomen x
Akathisia Akathisia x
Hyperkinesia Hyperkinesia x
Bradycardia Bradycardia x x
Laboratory test abnormal Laboratory test abnormal x
Lymphadenopathy Lymphadenopathy x x
Blood pressure increased Blood pressure increased x
Sudden death Sudden death, cause unknown x
Vasculitic rash Vasculitic rash x
Electrocardiogram abnormal Electrocardiogram abnormal x
Face oedema Face oedema x x
Gait disturbance Gait disturbance x
Serotonin syndrome Serotonin syndrome x
Acne Acne x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Hallucinations, mixed Auditory and visual hallucinations x
Thrombocytosis Thrombocytosis x
Sleep disorder Sleep disorder x
Cerebral ischaemia Cerebral ischaemia x
Insomnia Insomnia x x
Muscular weakness Myasthenia x
Parosmia Parosmia x
Renal failure Renal impairment x
Renal impairment Renal impairment x
Breast enlargement Breast enlargement x
Somnolence Somnolence x x
Ejaculation disorder Abnormal ejaculation x
Right ventricular failure Right ventricular failure x
Vaginal haemorrhage Vaginal haemorrhage x
Visual impairment Abnormal vision x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

SIBUTRAMINE HYDROCHLORIDE / MERIDIA

Side effects:164
Source:FDA

SIBUTRAMINE HYDROCHLORIDE MONOHYDRATE / MERIDIA

Side effects:266
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label