Side effect information for Duloxetine

Side effects

Options: Hide MedDRA Preferred Terms , display all 47 labels

MedDRA Preferred Term	Side effect	Data for drug	Placebo	Labels
				1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Nausea	Nausea	9% - 30%	7% - 11%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Headache	Headache	very common, 9% - 20%	8% - 15%	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dry mouth	Dry mouth	3% - 18%	3% - 6%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Constipation	Constipation	2% - 15%	3% - 4%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dizziness	Dizziness	6% - 17%	5% - 7%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dizziness	Syncope	very rare, postmarketing					x	x														x
Asthenia	Fatigue	2% - 16%	5% - 8%		x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Asthenia	Asthenia	frequent, 2% - 8%	1%		x	x	x				x		x	x	x			x	x	x	x	x	x
Fatigue	Fatigue	2% - 16%	5% - 8%		x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Insomnia	Insomnia	5% - 16%	5% - 10%		x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Somnolence	Somnolence	5% - 21%	3% - 5%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Diarrhoea	Diarrhoea	7% - 13%	5% - 8%	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Diarrhoea	Loose stools	2% - 3%	1%															x				x	x
Decreased appetite	Decreased appetite	1% - 14%	1% - 2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Decreased appetite	Anorexia	3% - 5%	1%	x	x		x											x	x	x	x	x	x
Hyperhidrosis	Hyperhidrosis	2% - 10%	1% - 2%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hyperhidrosis	Sweating increased			x			x	x															x
Abdominal pain	Abdominal pain	common — 2% - 6%	4% - 5%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrointestinal pain	Abdominal pain	common — 2% - 6%	4% - 5%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrointestinal pain	Gastrointestinal pain				x		x												x	x	x	x	x
Neck pain	Neck pain	common					x												x	x	x	x	x
Hypoglycaemia	Hypoglycaemia	infrequent, frequent																					x
Nasopharyngitis	Nasopharyngitis	4% - 9%	4% - 5%	x			x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Nervousness	Nervousness	common, frequent		x	x		x	x											x	x	x	x	x
Nervousness	Feeling jittery	infrequent, common			x		x												x	x	x	x	x
Tension	Nervousness	common, frequent		x	x		x	x											x	x	x	x	x
Tension	Tension	infrequent, common					x															x	x
Nightmare	Nightmare	uncommon, frequent		x	x		x												x	x	x	x	x
Skin ulcer	Skin ulcer	infrequent, frequent																					x
Myalgia	Myalgia	common, 1% - 4%	1%				x											x	x	x	x	x	x
Musculoskeletal discomfort	Myalgia	common, 1% - 4%	1%				x											x	x	x	x	x	x
Musculoskeletal discomfort	Arthralgia			x			x																x
Increased appetite	Increased appetite	infrequent, frequent																					x
Abdominal discomfort	Upset stomach	common					x												x	x	x	x	x
Abdominal discomfort	Abdominal discomfort				x		x												x	x	x	x	x
Initial insomnia	Initial insomnia	frequent		x	x		x												x	x	x	x	x
Middle insomnia	Middle insomnia	frequent		x	x		x												x	x	x	x	x
Feeling jittery	Feeling jittery	infrequent, common			x		x												x	x	x	x	x
Libido decreased	Libido decreased	frequent, 1% - 6%	0% - 2%	x	x		x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Disturbance in sexual arousal	Libido decreased	frequent, 1% - 6%	0% - 2%	x	x		x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Muscle spasms	Cramp muscle	4% - 5%	3%															x				x	x
Muscle spasms	Muscle spasms	postmarketing — 2% - 4%	2% - 3%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Upper respiratory tract infection	Upper respiratory tract infection	3% - 7%	3% - 6%	x			x		x	x	x	x	x	x	x	x	x	x	x	x	x		x
Vomiting	Vomiting	3% - 6%	2% - 4%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Agitation	Agitation	infrequent — 1% - 6%	1% - 3%		x		x	x	x	x	x	x	x	x	x	x	x	x			x	x	x
Erectile dysfunction	Erectile dysfunction	0% - 5%	0% - 1%	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Anxiety	Anxiety	common — 3%	2%	x	x		x	x	x	x	x	x	x	x	x	x	x	x			x	x	x
Back pain	Back pain	2% - 5%	3%	x			x							x	x	x	x						x
Back pain	Low back pain					x						x	x		x		x			x
Cough	Cough	2% - 6%	2% - 4%	x			x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Seasonal allergy	Seasonal allergy	3%	2%															x
Rhinitis seasonal	Seasonal allergy	3%	2%															x
Influenza	Influenza	2% - 3%	2%				x		x	x	x	x	x	x	x	x	x	x	x	x	x		x
Musculoskeletal pain	Musculoskeletal pain	postmarketing — 3% - 5%	3% - 4%		x	x					x	x	x	x	x	x	x	x	x	x	x	x	x
Tremor	Tremor	0% - 5%	0% - 1%	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Urinary tract infection	Urinary tract infection	3%	3%															x
Migraine	Migraine	3%	3%															x
Ejaculation delayed	Ejaculation delayed	frequent, 2% - 3%	1%	x	x		x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x
Vision blurred	Vision blurred	postmarketing — 2% - 3%	1% - 2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Laryngeal pain	Pharyngolaryngeal pain	1% - 6%	1% - 3%				x											x				x	x
Pain	Pain	postmarketing, 4%	4%		x		x																x
Dyspepsia	Dyspepsia	common — 2% - 5%	1% - 3%	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Body temperature increased	Body temperature increased	1% - 3%	1%															x				x	x
Orgasm abnormal	Orgasm abnormal	postmarketing — 2% - 4%	0% - 1%	x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Palpitations	Palpitations	postmarketing — 2%	1% - 2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Paraesthesia	Paraesthesia	postmarketing — 1% - 4%	2% - 4%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Penis disorder	Penis disorder	2%	0%															x
Weight decreased	Weight decreased	postmarketing — 2%	1%		x				x	x	x	x	x	x	x	x	x	x	x	x	x		x
Yawning	Yawning	postmarketing — 2%	1%		x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Viral diarrhoea	Viral diarrhoea	2%	2%															x
Ejaculation disorder	Ejaculation disorder	uncommon — 2% - 4%	0% - 1%	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blood pressure increased	Blood pressure increased	uncommon, 2%	1%				x	x								x	x					x
Oropharyngeal pain	Oropharyngeal pain	postmarketing — 2%	2%						x	x	x	x	x	x	x	x	x		x	x	x	x
Pollakiuria	Pollakiuria	postmarketing — 1% - 5%	2%				x									x	x	x					x
Pollakiuria	Micturition urgency	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Alopecia	Alopecia	infrequent		x																			x
Anaemia	Anaemia	infrequent		x																			x
Ataxia	Ataxia	infrequent
Atrial fibrillation	Atrial fibrillation	infrequent						x															x
Colitis	Colitis	rare, infrequent		x																			x
Conjunctivitis	Conjunctivitis	infrequent																					x
Dermatitis exfoliative	Dermatitis exfoliative	rare, infrequent																					x
Diverticulitis	Diverticulitis	rare, infrequent																					x
Eczema	Eczema	infrequent		x																			x
Oedema	Oedema	infrequent																					x
Flushing	Flushing	postmarketing — 2% - 3%	1%		x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gingivitis	Gingivitis	rare, infrequent		x																			x
Cardiac failure	Cardiac failure	rare, infrequent																					x
Cardiac failure congestive	Cardiac failure congestive	rare, infrequent																					x
Hypercholesterolaemia	Hypercholesterolaemia	infrequent																					x
Irritable bowel syndrome	Irritable bowel syndrome	infrequent		x																			x
Functional gastrointestinal disorder	Irritable bowel syndrome	infrequent		x																			x
Nephropathy	Nephropathy	rare, infrequent																					x
Leukopenia	Leukopenia	infrequent		x																			x
Macular degeneration	Macular degeneration	rare, infrequent																					x
Mydriasis	Mydriasis	uncommon						x														x
Oliguria	Oliguria	rare, infrequent																					x
Phlebitis	Phlebitis	rare, infrequent		x																			x
Prurigo	Prurigo	infrequent
Retinal detachment	Retinal detachment	rare, infrequent																					x
Thrombocytopenia	Thrombocytopenia	postmarketing, infrequent		x			x																x
Urinary incontinence	Urinary incontinence	infrequent		x																			x
Urinary retention	Urinary retention	postmarketing — uncommon		x			x	x														x	x
Bundle branch block right	Bundle branch block right	rare, infrequent																					x
Photopsia	Photopsia	rare, infrequent																					x
Oedema peripheral	Oedema peripheral	infrequent		x			x																x
Sjogren's syndrome	Syndrome sicca	infrequent
Gamma-glutamyltransferase increased	Gamma-glutamyltransferase increased	uncommon																				x
Liver function test abnormal	Liver function test abnormal	uncommon																				x
Muscular weakness	Muscular weakness	rare, infrequent																					x
Aspartate aminotransferase increased	Aspartate aminotransferase increased	postmarketing, uncommon					x															x
Alanine aminotransferase increased	Alanine aminotransferase increased	postmarketing, uncommon					x															x
Urinary hesitation	Urinary hesitation	infrequent — frequent		x			x	x														x	x
Abdominal pain lower	Abdominal pain lower	infrequent		x	x		x												x	x	x	x	x
Pressure of speech	Pressure of speech	rare, infrequent		x																			x
Abnormal dreams	Abnormal dreams	postmarketing — 2% - 3%	1%		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Rash erythematous	Rash erythematous	infrequent
Blood creatinine increased	Blood creatinine increased	rare, infrequent																					x
Hepatic enzyme increased	Hepatic enzyme increased	uncommon						x														x
Blood pressure systolic increased	Blood pressure systolic increased	uncommon																				x
Blood pressure diastolic increased	Blood pressure diastolic increased	uncommon																				x
Ejaculation failure	Ejaculation failure	uncommon		x	x		x												x	x	x	x	x
Epigastric discomfort	Gastric irritation	infrequent
Lymphadenopathy	Lymphadenopathy	infrequent		x																			x
Coordination abnormal	Coordination abnormal	infrequent																					x
Influenza like illness	Influenza like illness	infrequent																					x
Impaired gastric emptying	Impaired gastric emptying	rare, infrequent																					x
Face oedema	Face oedema	rare, infrequent		x																			x
Urine flow decreased	Urine flow decreased	rare, infrequent		x				x														x	x
Maculopathy	Maculopathy	rare, infrequent																					x
White blood cell count increased	White blood cell count increased	rare, infrequent		x																			x
Oropharyngeal swelling	Oropharyngeal swelling	infrequent
Oesophageal stenosis	Oesophageal stenosis acquired	infrequent		x
Oesophageal stenosis	Oesophageal stenosis	rare																					x
Hyperkeratosis	Hyperkeratosis	rare, infrequent																					x
Hypersomnia	Hypersomnia	infrequent, frequent					x													x		x	x
Sluggishness	Sluggishness	rare, infrequent		x																			x
Musculoskeletal stiffness	Musculoskeletal stiffness	uncommon																				x
Haematochezia	Blood in stool	infrequent		x
Haematochezia	Haematochezia	postmarketing, rare			x	x	x	x	x	x	x	x	x					x	x	x	x		x
Coronary artery disease	Coronary artery disease	infrequent																					x
Hepatic steatosis	Hepatic steatosis	rare, infrequent																					x
Loss of libido	Loss of libido	infrequent			x														x	x	x	x	x
Dysphagia	Dysphagia	postmarketing, infrequent		x												x	x						x
Hypertriglyceridaemia	Hypertriglyceridaemia	rare, infrequent																					x
Blood triglycerides increased	Hypertriglyceridaemia	rare, infrequent																					x
Aggression	Aggression	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Anaphylactic shock	Anaphylactic shock	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Anger	Anger	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Angioedema	Angioedema	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Mental disorder	Mental disorder	postmarketing		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Breast disorder	Breast disorder	postmarketing			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Bruxism	Bruxism	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Infection	Infection	postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Confusional state	Confusional state	postmarketing — uncommon			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Feeling abnormal	Confusional state	postmarketing — uncommon			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
	Malaise	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
	Feeling abnormal	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Connective tissue disorder	Connective tissue disorder	postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dehydration	Dehydration	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dermatitis contact	Dermatitis contact	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x		x	x	x
Diplopia	Diplopia	postmarketing, infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Dysarthria	Dysarthria	postmarketing — infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Osteoarthritis	Dysarthria	postmarketing — infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Osteoarthritis	Osteoarthritis					x						x	x		x		x			x
Dysgeusia	Dysgeusia	postmarketing — 3%	1%		x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dyskinesia	Dyskinesia	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dysuria	Dysuria	postmarketing — frequent		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Ear pain	Ear pain	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Ecchymosis	Ecchymosis	postmarketing — infrequent		x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x		x
Endocrine disorder	Endocrine disorder	postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Eructation	Eructation	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Erythema multiforme	Erythema multiforme	postmarketing				x	x											x					x
Erythema multiforme	Stevens-Johnson syndrome	very rare, postmarketing				x	x	x										x				x	x
Dermatitis	Rash	postmarketing — 4%	2%	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Rash	Rash	postmarketing — 4%	2%	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Extrapyramidal disorder	Extrapyramidal disorder	very rare, postmarketing				x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Extrapyramidal disorder	Extrapyramidal symptoms
Eye disorder	Eye disorder	postmarketing, 3%	2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Flatulence	Flatulence	postmarketing — frequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastritis	Gastritis	postmarketing — frequent		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastroenteritis	Gastroenteritis	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrointestinal disorder	Gastrointestinal disorder	postmarketing, 14% - 30%	9%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrointestinal haemorrhage	Gastrointestinal haemorrhage	postmarketing — uncommon					x	x						x	x	x	x					x
Glaucoma	Glaucoma	very rare — infrequent				x	x	x	x	x		x		x	x			x	x	x	x	x	x
Angle closure glaucoma	Angle closure glaucoma	postmarketing									x		x			x	x
Breath odour	Breath odour	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hallucination	Hallucination	postmarketing, rare				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Cardiac disorder	Cardiac disorder	postmarketing, 2%	2%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blood disorder	Blood disorder	postmarketing					x															x
Haemorrhage	Haemorrhage	very rare, postmarketing				x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Haemoglobin	Haemorrhage	very rare, postmarketing				x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hyperglycaemia	Hyperglycaemia	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hyperlipidaemia	Hyperlipidaemia	postmarketing, infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Hyperprolactinaemia	Hyperprolactinaemia	very rare, postmarketing							x	x	x	x	x	x	x	x	x		x	x	x	x
Hypersensitivity	Hypersensitivity	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypertensive crisis	Hypertensive crisis	very rare — infrequent				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypoaesthesia	Hypoaesthesia	postmarketing — frequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypoaesthesia	Hypoaesthesia facial						x												x	x	x
Orthostatic hypotension	Orthostatic hypotension	very rare — uncommon			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypothyroidism	Hypothyroidism	postmarketing — infrequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Immune system disorder	Immune system disorder	postmarketing					x	x										x				x
Irritability	Irritability	postmarketing — frequent		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Laryngitis	Laryngitis	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Lethargy	Lethargy	postmarketing — frequent		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Mediastinal disorder	Mediastinal disorder	postmarketing, 2%	1%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Melaena	Melaena	postmarketing — infrequent			x	x			x	x	x	x	x					x	x	x	x		x
Menstrual disorder	Menstrual disorder	postmarketing, rare												x	x	x	x					x
Myocardial infarction	Myocardial infarction	postmarketing, infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Acute coronary syndrome	Myocardial infarction	postmarketing, infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Myoclonus	Myoclonus	postmarketing — infrequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Nervous system disorder	Nervous system disorder	postmarketing		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Night sweats	Night sweats	postmarketing — frequent		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Nocturia	Nocturia	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Polyuria	Polyuria	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Urine output increased	Polyuria	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Pruritus	Pruritus	postmarketing — 3%	2%	x			x							x	x	x	x	x				x	x
Restless legs syndrome	Restless legs syndrome	very rare, postmarketing				x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Convulsion	Convulsion	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Stevens-Johnson syndrome	Stevens-Johnson syndrome	very rare, postmarketing				x	x	x										x				x	x
Gastric ulcer	Gastric ulcer	postmarketing — infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Stomatitis	Stomatitis	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Aphthous stomatitis	Aphthous stomatitis	rare																					x
Suicide attempt	Suicide attempt	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Tachycardia	Tachycardia	postmarketing — uncommon			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Testicular pain	Testicular pain	postmarketing, infrequent														x	x
Thirst	Thirst	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Tinnitus	Tinnitus	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Trismus	Trismus	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Erythema	Erythema	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Urethral disorder	Urinary tract disorder	postmarketing							x	x	x	x	x	x	x	x	x	x	x	x	x
Urinary tract disorder	Urinary tract disorder	postmarketing							x	x	x	x	x	x	x	x	x	x	x	x	x
Urticaria	Urticaria	very rare, postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Angiopathy	Angiopathy	postmarketing, 2% - 3%	1%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Vertigo	Vertigo	postmarketing — frequent			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Weight increased	Weight increased	postmarketing — 2%	1%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Chills	Chills	postmarketing — frequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Chills	Rigors	postmarketing — frequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Micturition urgency	Micturition urgency	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Apathy	Apathy	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Flat affect	Apathy	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Mood swings	Mood swings	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Affect lability	Mood swings	postmarketing, infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Malnutrition	Malnutrition	postmarketing, 7% - 9%	1% - 2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Photosensitivity reaction	Photosensitivity reaction	postmarketing — uncommon		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Skin disorder	Unspecified disorder of skin and subcutaneous tissue	postmarketing, 6%	1% - 2%	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Malaise	Malaise	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Discomfort	Malaise	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Ill-defined disorder	Malaise	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Muscle twitching	Muscle twitching	postmarketing — frequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Cold sweat	Cold sweat	postmarketing — uncommon		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Disorientation	Disorientation	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Disturbance in attention	Disturbance in attention	postmarketing — uncommon			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Anorgasmia	Anorgasmia	postmarketing, frequent		x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Galactorrhoea	Galactorrhoea	very rare, postmarketing							x	x	x	x	x	x	x	x	x		x	x	x	x
Pharyngeal oedema	Pharyngeal oedema	rare																					x
Throat tightness	Throat tightness	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Menopausal symptoms	Menopausal symptoms	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Menopausal symptoms	Hot flush	postmarketing — 2% - 3%	1% - 2%	x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dyslipidaemia	Dyslipidaemia	postmarketing — infrequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Hepatobiliary disease	Hepatobiliary disease	postmarketing					x	x														x	x
Peripheral coldness	Peripheral coldness	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Urine odour abnormal	Urine odour abnormal	postmarketing — infrequent			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blood bilirubin increased	Blood bilirubin increased	very rare — uncommon					x															x
Dry eye	Dry eye	postmarketing — uncommon												x	x	x	x					x
Mania	Mania	very rare — infrequent		x			x	x														x	x
Increased tendency to bruise	Increased tendency to bruise	postmarketing, infrequent		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x		x
Arrhythmia supraventricular	Arrhythmia supraventricular	very rare, postmarketing				x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Visual impairment	Visual disturbance	postmarketing, infrequent			x	x		x	x	x	x	x	x					x	x	x	x		x
Visual impairment	Visual impairment	postmarketing — uncommon												x	x	x	x					x
Sexual dysfunction	Sexual dysfunction	postmarketing — uncommon		x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gait disturbance	Gait disturbance	postmarketing, rare			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blood cholesterol increased	Blood cholesterol increased	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hot flush	Hot flush	postmarketing — 2% - 3%	1% - 2%	x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Infestation	Infestation NOS	postmarketing				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Sleep disorder	Sleep disorder	postmarketing — 3%	2%	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Sleep disorder	Sleep disturbance							x
Completed suicide	Completed suicide	postmarketing — infrequent		x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Muscle tightness	Muscle tightness	postmarketing — frequent			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Poor quality sleep	Poor quality sleep	postmarketing — uncommon			x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x
Feeling hot	Feeling hot	postmarketing — uncommon			x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hepatitis	Hepatitis	very rare, postmarketing					x	x														x
Hyponatraemia	Hyponatraemia	very rare, postmarketing					x	x														x
Inappropriate antidiuretic hormone secretion	Inappropriate antidiuretic hormone secretion	very rare, postmarketing					x	x														x
Jaundice	Jaundice	very rare, postmarketing					x	x														x
Shock	Syncope	very rare, postmarketing					x	x														x
Syncope	Syncope	very rare, postmarketing					x	x														x
Loss of consciousness	Syncope	very rare, postmarketing					x	x														x
Blood alkaline phosphatase increased	Phosphatase alkaline increased	very rare, postmarketing					x															x
Diabetes mellitus	Diabetic	very rare
Diabetes mellitus	Diabetes mellitus					x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x
Serotonin syndrome	Serotonin syndrome	very rare, postmarketing					x	x														x
Arrhythmia	Arrhythmia							x
Arthralgia	Arthralgia			x			x																x
Chest pain	Chest pain							x
Contusion	Contusion						x
Electric shock	Electric shock
Epistaxis	Epistaxis							x
Hypertension	Hypertension							x
Pain in extremity	Pain in extremity						x
Pancreatitis	Pancreatitis																					x
Pharyngitis	Pharyngitis			x			x																x
Rhabdomyolysis	Rhabdomyolysis																					x
Supraventricular tachycardia	Supraventricular tachycardia							x
Essential hypertension	Essential hypertension
Hepatic failure	Hepatic failure						x	x														x
Ventricular arrhythmia	Ventricular arrhythmia																					x
Drug withdrawal syndrome	Withdrawal symptom							x
Blood creatine phosphokinase increased	Creatine phosphokinase increased							x
Blood creatine phosphokinase increased	Blood creatine phosphokinase increased
Secondary hypertension	Secondary hypertension
Liver injury	Liver injury						x
Liver injury	Acute liver injury							x
Traumatic liver injury	Liver injury						x
Systolic hypertension	Systolic hypertension
Cardiac fibrillation	Cardiac fibrillation
Abdominal pain upper	Abdominal pain upper			x	x		x												x	x	x	x	x
Abdominal tenderness	Abdominal tenderness				x		x												x	x	x	x	x
Diastolic hypertension	Diastolic hypertension
Hepatotoxicity	Hepatotoxicity						x
Glycosylated haemoglobin increased	Glycosylated haemoglobin increased						x
Blood pressure diastolic decreased	Blood pressure diastolic decreased						x
Akathisia	Akathisia							x
Suicidal ideation	Suicidal ideation							x
Paraesthesia oral	Paraesthesia oral						x														x
Terminal insomnia	Terminal insomnia				x		x												x	x	x	x	x
Orthostatic hypertension	Orthostatic hypertension
Haemorrhagic disorder	Hemorrhage abnormal																					x
Blood potassium increased	Blood potassium increased
Blood glucose increased	Fasting blood glucose increased						x
Renal failure	Renal impairment																					x
Renal impairment	Renal impairment																					x
Suicidal behaviour	Suicidal behaviour
Genital hypoaesthesia	Genital hypoaesthesia
Labile hypertension	Labile hypertension

Side effects:	87
Source:	FDA

Side effects:	122
Source:	FDA Structured Product Label

Side effects:	123
Source:	FDA Structured Product Label

Side effects:	128
Source:	Health Canada

Side effects:	133
Source:	EMA

Search results :

Duloxetine

Side effects

Indications

DULOXETINE HYDROCHLORIDE / CYMBALTA

DULOXETINE

DULOXETINE

DULOXETINE (DULOXETINE HYDROCHLORIDE) / CYMBALTA

duloxetine / duloxetine

DULOXETINE

DULOXETINE

DULOXETINE

DULOXETINE

DULOXETINE

Duloxetine

Duloxetine

Duloxetine

Duloxetine

Duloxetine

DULOXETINE

DULOXETINE

DULOXETINE

Duloxetine hydrochloride / DULOXETINE ENTERIC CAPSULES

DULOXETINE HYDROCHLORIDE / CYMBALTA

Color scheme:

Indication	Labels
Agitation	x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Anxiety		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Bradypsychic response	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Cerebration impaired	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Chronic pain			x					x		x	x	x	x	x			x
Decreased interest	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Depressed mood	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Diabetic				x	x														x
Diabetic peripheral neuropathic pain		x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x		x
Diabetic peripheral neuropathy		x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x		x
Distress		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Dysphoria	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Fatigue	x	x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Feeling guilty	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Fibromyalgia		x	x								x	x	x	x	x
Generalised anxiety disorder		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypersensitivity																				x
Hypersomnia	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Insomnia	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Irritability		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Low back pain								x			x		x
Major depression	x	x	x	x		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Major depressive disorder, single episode	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Musculoskeletal pain			x					x		x	x	x	x	x			x
Neuralgia		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Osteoarthritis								x			x		x
Sleep disturbance		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x
Suicidal ideation	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Suicide attempt	x	x	x			x	x	x	x	x	x	x	x	x	x	x		x		x
Tension		x	x			x	x	x	x	x	x	x	x	x	x	x	x	x		x

		100%
		75%
		50%
		10%
		frequent (1% to 100%)
		infrequent (0.1% to 1%)
		rare (<0.1%)
		postmarketing
		0%
		no frequency information
		not found on label