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Duloxetine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N06AX21

Side effects

Options: Show MedDRA Preferred Terms,   display all 47 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Nausea 9% - 30% 7% - 11% x x x x x x x x x x x x x x x x x x x x
Headache very common, 9% - 20% 8% - 15% x x x x x x x x x x x x x x x x x x x
Dry mouth 3% - 18% 3% - 6% x x x x x x x x x x x x x x x x x x x x
Constipation 2% - 15% 3% - 4% x x x x x x x x x x x x x x x x x x x x
Dizziness 6% - 17% 5% - 7% x x x x x x x x x x x x x x x x x x x x
Fatigue 2% - 16% 5% - 8% x x x x x x x x x x x x x x x x x
Insomnia 5% - 16% 5% - 10% x x x x x x x x x x x x x x x x x
Somnolence 5% - 21% 3% - 5% x x x x x x x x x x x x x x x x x x x x
Diarrhoea 7% - 13% 5% - 8% x x x x x x x x x x x x x x x x x x x
Decreased appetite 1% - 14% 1% - 2% x x x x x x x x x x x x x x x x x x x x
Hyperhidrosis 2% - 10% 1% - 2% x x x x x x x x x x x x x x x x x x x
Abdominal pain common — 2% - 6% 4% - 5% x x x x x x x x x x x x x x x x x
Neck pain common x x x x x x
Hypoglycaemia infrequent, frequent x
Nasopharyngitis 4% - 9% 4% - 5% x x x x x x x x x x x x x x x x
Nervousness common, frequent x x x x x x x x x x
Nightmare uncommon, frequent x x x x x x x
Skin ulcer infrequent, frequent x
Myalgia common, 1% - 4% 1% x x x x x x x x
Increased appetite infrequent, frequent x
Tension infrequent, common x x x
Upset stomach common x x x x x
Initial insomnia frequent x x x x x x x x
Middle insomnia frequent x x x x x x x x
Feeling jittery infrequent, common x x x x x x x
Asthenia frequent, 2% - 8% 1% x x x x x x x x x x x x
Libido decreased frequent, 1% - 6% 0% - 2% x x x x x x x x x x x x x x x x x x
Cramp muscle 4% - 5% 3% x x x
Upper respiratory tract infection 3% - 7% 3% - 6% x x x x x x x x x x x x x x x
Vomiting 3% - 6% 2% - 4% x x x x x x x x x x x x x x x x x x x x
Agitation infrequent — 1% - 6% 1% - 3% x x x x x x x x x x x x x x x x
Erectile dysfunction 0% - 5% 0% - 1% x x x x x x x x x x x x x x x x x x x
Anorexia 3% - 5% 1% x x x x x x x x
Anxiety common — 3% 2% x x x x x x x x x x x x x x x x x
Back pain 2% - 5% 3% x x x x x x
Cough 2% - 6% 2% - 4% x x x x x x x x x x x x x x x x
Seasonal allergy 3% 2% x
Influenza 2% - 3% 2% x x x x x x x x x x x x x x
Musculoskeletal pain postmarketing — 3% - 5% 3% - 4% x x x x x x x x x x x x x x
Tremor 0% - 5% 0% - 1% x x x x x x x x x x x x x x x x x x x
Urinary tract infection 3% 3% x
Migraine 3% 3% x
Ejaculation delayed frequent, 2% - 3% 1% x x x x x x x x x x x x x x x x x x
Vision blurred postmarketing — 2% - 3% 1% - 2% x x x x x x x x x x x x x x x x x x x x
Pharyngolaryngeal pain 1% - 6% 1% - 3% x x x x
Pain postmarketing, 4% 4% x x x
Dyspepsia common — 2% - 5% 1% - 3% x x x x x x x x x x x x x x x x x x
Body temperature increased 1% - 3% 1% x x x
Orgasm abnormal postmarketing — 2% - 4% 0% - 1% x x x x x x x x x x x x x x x x x x x
Palpitations postmarketing — 2% 1% - 2% x x x x x x x x x x x x x x x x x x x x
Paraesthesia postmarketing — 1% - 4% 2% - 4% x x x x x x x x x x x x x x x x x x x
Penis disorder 2% 0% x
Muscle spasms postmarketing — 2% - 4% 2% - 3% x x x x x x x x x x x x x x x x x
Weight decreased postmarketing — 2% 1% x x x x x x x x x x x x x x
Yawning postmarketing — 2% 1% x x x x x x x x x x x x x x x x x x
Viral diarrhoea 2% 2% x
Ejaculation disorder uncommon — 2% - 4% 0% - 1% x x x x x x x x x x x x x x x x x x x
Blood pressure increased uncommon, 2% 1% x x x x x x
Loose stools 2% - 3% 1% x x x
Oropharyngeal pain postmarketing — 2% 2% x x x x x x x x x x x x
Pollakiuria postmarketing — 1% - 5% 2% x x x x x x
Alopecia infrequent x x
Anaemia infrequent x x
Ataxia infrequent
Atrial fibrillation infrequent x x x
Colitis rare, infrequent x x
Conjunctivitis infrequent x
Dermatitis exfoliative rare, infrequent x
Diverticulitis rare, infrequent x
Eczema infrequent x x
Oedema infrequent x
Flushing postmarketing — 2% - 3% 1% x x x x x x x x x x x x x x x x x x
Gingivitis rare, infrequent x x
Cardiac failure rare, infrequent x
Cardiac failure congestive rare, infrequent x
Hypercholesterolaemia infrequent x
Irritable bowel syndrome infrequent x x
Nephropathy rare, infrequent x
Leukopenia infrequent x x
Macular degeneration rare, infrequent x
Mydriasis uncommon x x x
Oliguria rare, infrequent x
Phlebitis rare, infrequent x x
Prurigo infrequent
Retinal detachment rare, infrequent x
Thrombocytopenia postmarketing, infrequent x x x
Urinary incontinence infrequent x x
Urinary retention postmarketing — uncommon x x x x x x
Bundle branch block right rare, infrequent x
Photopsia rare, infrequent x
Oedema peripheral infrequent x x x
Syndrome sicca infrequent
Gamma-glutamyltransferase increased uncommon x
Liver function test abnormal uncommon x
Muscular weakness rare, infrequent x
Aspartate aminotransferase increased postmarketing, uncommon x x
Alanine aminotransferase increased postmarketing, uncommon x x
Urinary hesitation infrequent — frequent x x x x x x
Abdominal pain lower infrequent x x x x x x x x
Pressure of speech rare, infrequent x x
Abnormal dreams postmarketing — 2% - 3% 1% x x x x x x x x x x x x x x x x x
Rash erythematous infrequent
Blood creatinine increased rare, infrequent x
Hepatic enzyme increased uncommon x x x
Blood pressure systolic increased uncommon x x
Blood pressure diastolic increased uncommon x x
Ejaculation failure uncommon x x x x x x x x
Gastric irritation infrequent
Lymphadenopathy infrequent x x
Coordination abnormal infrequent x
Influenza like illness infrequent x
Impaired gastric emptying rare, infrequent x
Face oedema rare, infrequent x x
Urine flow decreased rare, infrequent x x x x x
Maculopathy rare, infrequent x
White blood cell count increased rare, infrequent x x
Oropharyngeal swelling infrequent
Oesophageal stenosis acquired infrequent x
Hyperkeratosis rare, infrequent x
Hypersomnia infrequent, frequent x x x x
Sluggishness rare, infrequent x x
Musculoskeletal stiffness uncommon x
Blood in stool infrequent x
Coronary artery disease infrequent x
Hepatic steatosis rare, infrequent x
Loss of libido infrequent x x x x x x
Dysphagia postmarketing, infrequent x x x x x
Hypertriglyceridaemia rare, infrequent x
Aggression very rare, postmarketing x x x x x x x x x x x x x x x x x
Anaphylactic shock very rare, postmarketing x x x x x x x x x x x x x x x x x x
Anger very rare, postmarketing x x x x x x x x x x x x x x x x x
Angioedema very rare, postmarketing x x x x x x x x x x x x x x x x x x
Mental disorder postmarketing x x x x x x x x x x x x x x x x x x x x
Breast disorder postmarketing x x x x x x x x x x x x x x x x x x x
Bruxism postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Infection postmarketing x x x x x x x x x x x x x x x x x x
Confusional state postmarketing — uncommon x x x x x x x x x x x x x x x x
Connective tissue disorder postmarketing x x x x x x x x x x x x x x x x x x
Dehydration postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Dermatitis contact postmarketing — uncommon x x x x x x x x x x x x x x x x
Diplopia postmarketing, infrequent x x x x x x x x x x x x x x x
Dysarthria postmarketing — infrequent x x x x x x x x x x x x x x x
Dysgeusia postmarketing — 3% 1% x x x x x x x x x x x x x x x x x x
Dyskinesia postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Dysuria postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Ear pain postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Ecchymosis postmarketing — infrequent x x x x x x x x x x x x x x x x x
Endocrine disorder postmarketing x x x x x x x x x x x x x x x x x
Eructation postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Erythema multiforme postmarketing x x x x
Oesophageal stenosis rare x
Rash postmarketing — 4% 2% x x x x x x x x x x x x x x x x x x x
Extrapyramidal disorder very rare, postmarketing x x x x x x x x x x x x x x x x
Eye disorder postmarketing, 3% 2% x x x x x x x x x x x x x x x x x x x x
Flatulence postmarketing — frequent x x x x x x x x x x x x x x x x x x
Gastritis postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Gastroenteritis postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder postmarketing, 14% - 30% 9% x x x x x x x x x x x x x x x x x x x x
Gastrointestinal haemorrhage postmarketing — uncommon x x x x x x x
Glaucoma very rare — infrequent x x x x x x x x x x x x x x x
Angle closure glaucoma postmarketing x x x
Breath odour postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Hallucination postmarketing, rare x x x x x x x x x x x x x x x x x x
Cardiac disorder postmarketing, 2% 2% x x x x x x x x x x x x x x x x x x x
Haematochezia postmarketing, rare x x x x x x x x x x x x x x x
Blood disorder postmarketing x x
Haemorrhage very rare, postmarketing x x x x x x x x x x x x x x x x
Hyperglycaemia very rare, postmarketing x x x x x x x x x x x x x x x x x
Hyperlipidaemia postmarketing, infrequent x x x x x x x x x x x x x x x
Hyperprolactinaemia very rare, postmarketing x x x x x x x x x x x x x
Hypersensitivity very rare, postmarketing x x x x x x x x x x x x x x x x x
Hypertensive crisis very rare — infrequent x x x x x x x x x x x x x x x x x x
Hypoaesthesia postmarketing — frequent x x x x x x x x x x x x x x x x
Orthostatic hypotension very rare — uncommon x x x x x x x x x x x x x x x x x x x
Hypothyroidism postmarketing — infrequent x x x x x x x x x x x x x x x x x
Immune system disorder postmarketing x x x x x
Irritability postmarketing — frequent x x x x x x x x x x x x x x x x x x x x
Laryngitis postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Lethargy postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Mediastinal disorder postmarketing, 2% 1% x x x x x x x x x x x x x x x x x x x
Melaena postmarketing — infrequent x x x x x x x x x x x x
Menstrual disorder postmarketing, rare x x x x x
Myocardial infarction postmarketing, infrequent x x x x x x x x x x x x x x x x
Myoclonus postmarketing — infrequent x x x x x x x x x x x x x x x x x x
Nervous system disorder postmarketing x x x x x x x x x x x x x x x x x x x x
Night sweats postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Nocturia postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Polyuria postmarketing — uncommon x x x x x x x x x x x x x x x x x
Pruritus postmarketing — 3% 2% x x x x x x x x
Restless legs syndrome very rare, postmarketing x x x x x x x x x x x x x x x x
Convulsion very rare, postmarketing x x x x x x x x x x x x x x x x x
Stevens-Johnson syndrome very rare, postmarketing x x x x x x x
Gastric ulcer postmarketing — infrequent x x x x x x x x x x x x x x x x
Stomatitis postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Aphthous stomatitis rare x
Suicide attempt postmarketing, infrequent x x x x x x x x x x x x x x x x
Tachycardia postmarketing — uncommon x x x x x x x x x x x x x x x x
Testicular pain postmarketing, infrequent x x x
Thirst postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Tinnitus postmarketing — uncommon x x x x x x x x x x x x x x x x x
Trismus very rare, postmarketing x x x x x x x x x x x x x x x x x x
Erythema postmarketing, infrequent x x x x x x x x x x x x x x x x
Urinary tract disorder postmarketing x x x x x x x x x x x
Urticaria very rare, postmarketing x x x x x x x x x x x x x x x x x x
Angiopathy postmarketing, 2% - 3% 1% x x x x x x x x x x x x x x x x x x x x
Vertigo postmarketing — frequent x x x x x x x x x x x x x x x x x x x
Weight increased postmarketing — 2% 1% x x x x x x x x x x x x x x x x x x x x
Chills postmarketing — frequent x x x x x x x x x x x x x x x x x x
Micturition urgency postmarketing, infrequent x x x x x x x x x x x x x x x x
Apathy postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Mood swings postmarketing, infrequent x x x x x x x x x x x x x x x x
Malnutrition postmarketing, 7% - 9% 1% - 2% x x x x x x x x x x x x x x x x x x x x
Photosensitivity reaction postmarketing — uncommon x x x x x x x x x x x x x x x x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing, 6% 1% - 2% x x x x x x x x x x x x x x x x x x x
Malaise postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Muscle twitching postmarketing — frequent x x x x x x x x x x x x x x x x x x
Cold sweat postmarketing — uncommon x x x x x x x x x x x x x x x x x x x
Disorientation postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Disturbance in attention postmarketing — uncommon x x x x x x x x x x x x x x x x x
Anorgasmia postmarketing, frequent x x x x x x x x x x x x x x x x x x
Galactorrhoea very rare, postmarketing x x x x x x x x x x x x x
Pharyngeal oedema rare x
Throat tightness postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Menopausal symptoms postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Dyslipidaemia postmarketing — infrequent x x x x x x x x x x x x x x x
Hepatobiliary disease postmarketing x x x x x
Peripheral coldness postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Urine odour abnormal postmarketing — infrequent x x x x x x x x x x x x x x x x x x
Blood bilirubin increased very rare — uncommon x x
Dry eye postmarketing — uncommon x x x x
Mania very rare — infrequent x x x x x x
Increased tendency to bruise postmarketing, infrequent x x x x x x x x x x x x x x x x x x
Rigors postmarketing — frequent x x x x x x x x x x x x x x x x
Arrhythmia supraventricular very rare, postmarketing x x x x x x x x x x x x x x x x
Visual disturbance postmarketing, infrequent x x x x x x x x x x x x x
Sexual dysfunction postmarketing — uncommon x x x x x x x x x x x x x x x x x x x
Gait disturbance postmarketing, rare x x x x x x x x x x x x x x x x x
Blood cholesterol increased postmarketing — uncommon x x x x x x x x x x x x x x x x x
Hot flush postmarketing — 2% - 3% 1% - 2% x x x x x x x x x x x x x x x x x x
Infestation NOS postmarketing x x x x x x x x x x x x x x x x x x
Ear and labyrinth disorders postmarketing x x x x x x x x x x x x x x x x x
Sleep disorder postmarketing — 3% 2% x x x x x x x x x x x x x x x x x x x
Completed suicide postmarketing — infrequent x x x x x x x x x x x x x x x x
Muscle tightness postmarketing — frequent x x x x x x x x x x x x x x x x x
Poor quality sleep postmarketing — uncommon x x x x x x x x x x x x x x x x
Feeling abnormal postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Feeling hot postmarketing — uncommon x x x x x x x x x x x x x x x x x x
Visual impairment postmarketing — uncommon x x x x x
Hepatitis very rare, postmarketing x x x x
Hyponatraemia very rare, postmarketing x x x x
Inappropriate antidiuretic hormone secretion very rare, postmarketing x x x x
Jaundice very rare, postmarketing x x x x
Syncope very rare, postmarketing x x x x
Phosphatase alkaline increased very rare, postmarketing x x
Diabetic very rare
Serotonin syndrome very rare, postmarketing x x x x
Arrhythmia x x
Arthralgia x x x
Chest pain x x
Contusion x
Diabetes mellitus x x x x x x x x x x x x x x x
Electric shock x
Epistaxis x x
Hypertension x x x
Low back pain x x x x x x
Osteoarthritis x x x x x x
Pain in extremity x
Pancreatitis x
Pharyngitis x x x
Rhabdomyolysis x
Sleep disturbance x x
Supraventricular tachycardia x x
Essential hypertension x
Hepatic failure x x x x
Ventricular arrhythmia x
Withdrawal symptom x x
Creatine phosphokinase increased x
Secondary hypertension x
Liver injury x
Systolic hypertension x
Cardiac fibrillation
Abdominal discomfort x x x x x x x
Abdominal pain upper x x x x x x x x
Abdominal tenderness x x x x x x x
Extrapyramidal symptoms x
Diastolic hypertension x
Hepatotoxicity x
Glycosylated haemoglobin increased x
Blood pressure diastolic decreased x
Akathisia x x
Suicidal ideation x x
Paraesthesia oral x x
Terminal insomnia x x x x x x x
Orthostatic hypertension x
Gastrointestinal pain x x x x x x x
Sweating increased x x x x x
Hemorrhage abnormal x
Blood and lymphatic system disorders x x
Blood creatine phosphokinase increased x
Blood potassium increased x
Fasting blood glucose increased x
Renal impairment x
Hypoaesthesia facial x x x x
Suicidal behaviour x
Acute liver injury x x
Genital hypoaesthesia x
Labile hypertension x

Indications

Information about indications was extracted from the indications and usage sections of the labels.