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Ixabepilone

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01DC04

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Nausea Nausea 40% - 42% x x
Arthralgia Arthralgia 5% - 49% x x
Musculoskeletal discomfort Arthralgia 5% - 49% x x
Myalgia 5% - 49% x x
Myalgia Myalgia 5% - 49% x x
Vomiting Vomiting 2% - 29% x x
Neutropenia Neutropenia 2% - 36% x x
Diarrhoea Diarrhoea 9% - 39% x x
Decreased appetite Anorexia 15% - 19% x x
Asthenia Asthenia 4% - 56% x x
Fatigue 4% - 56% x x
Fatigue Fatigue 4% - 56% x x
Peripheral sensory neuropathy Peripheral sensory neuropathy 0% - 62% x x
Abdominal pain Abdominal pain 13% - 14% x x
Gastrointestinal pain Abdominal pain 13% - 14% x x
Leukopenia Leukopenia 1% - 41% x x
Stomatitis Stomatitis 4% - 29% x x
Mucosal inflammation Mucosal inflammation 4% - 29% x x
Nail disorder Nail disorder 0% - 10% x x
Dermatitis Rash 0% - 9% x x
Rash Rash 0% - 9% x x
Constipation Constipation 0% - 16% x x
Dizziness Dizziness 0% - 7% x x
Syncope x x
Oedema Oedema 0% - 9% x x
Musculoskeletal pain Musculoskeletal pain 0% - 20% x x
Pain Pain 0% - 9% x x
Body temperature increased Body temperature increased 0% - 8% x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease 0% - 8% x x
Dyspnoea Dyspnoea 1% - 9% x x
Chest pain Chest pain 0% - 5% x x
Anaemia Anaemia 1% - 8% x x
Dehydration Dehydration 2% x x
Thrombocytopenia Thrombocytopenia 2% - 5% x x
Lacrimation increased Lacrimation increased 0% - 4% x x
Febrile neutropenia Febrile neutropenia 1% - 3% x x
Headache Headache 0% - 11% x x
Pruritus Pruritus 0% - 6% x x
Skin exfoliation Skin exfoliation 0% - 3% x x
Insomnia Insomnia 0% - 5% x x
Neuritis Peripheral motor neuropathy 0% - 10% x x
Neuritis x
Peripheral motor neuropathy Peripheral motor neuropathy 0% - 10% x x
Alopecia Alopecia 0% - 48% x x
Angina pectoris Angina pectoris x x
Atrial flutter Atrial flutter x x
Bacterial infection Bacterial infection x x
Mental disorder Mental disorder x
Coagulopathy Coagulopathy x x
Bone disorder Bone disorder x x
Cognitive disorder Cognitive disorder x x
Colitis Colitis x x
Infection Infection x x
Connective tissue disorder Connective tissue disorder x
Cough Cough 0% - 2% x x
Dysphagia Dysphagia x x
Embolism Embolism x x
Enterocolitis Enterocolitis x x
Erythema multiforme Erythema multiforme x x
Oesophagitis Oesophagitis x x
Eye disorder Eye disorder x x
Gastritis Gastritis x x
Gastrointestinal disorder Gastrointestinal disorder x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x
Cardiac disorder Cardiac disorder x x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Hyperaesthesia Hyperaesthesia x
Hypersensitivity Hypersensitivity 0% - 5% x x
Hypoaesthesia Hypoaesthesia x
Hypokalaemia Hypokalaemia x x
Hyponatraemia Hyponatraemia x x
Hypotension Hypotension x x
Hypovolaemic shock Hypovolaemic shock x x
Immune system disorder Immune system disorder x x
Jaundice Jaundice x x
Laryngitis Laryngitis x x
Lethargy Lethargy x x
Lymphopenia Lymphopenia x x
Mediastinal disorder Mediastinal disorder x x
Myocardial infarction Myocardial infarction x x
Acute coronary syndrome Myocardial infarction x x
Nervous system disorder Nervous system disorder x x
Neuralgia Neuralgia x
Neuropathy peripheral Neuritis x
Neuropathy peripheral x x
Neuropathy x
Paraesthesia Paraesthesia x
Pneumonia Pneumonia x x
Renal failure Renal failure x x
Skin disorder Skin disorder x
Unspecified disorder of skin and subcutaneous tissue x x
Muscle spasms Muscle spasms x x
Shock Syncope x x
Syncope Syncope x x
Loss of consciousness Syncope x x
Thrombosis Thrombosis x x
Trismus Trismus x x
Upper respiratory tract infection Upper respiratory tract infection 0% - 6% x x
Urinary tract infection Urinary tract infection x x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Angiopathy Angiopathy x x
Vasculitis Vasculitis x x
Weight decreased Weight decreased 0% - 6% x x
Chills Chills x x
Burning sensation Burning sensation x
Lower respiratory tract infection Lower respiratory tract infection x x
Myocardial ischaemia Myocardial ischaemia x x
Muscular weakness Muscular weakness x x
Hyporeflexia Hyporeflexia x
Polyneuropathy Polyneuropathy x
Acute pulmonary oedema Acute pulmonary oedema x x
Malnutrition Malnutrition x x
Acute hepatic failure Acute hepatic failure x x
Skin hyperpigmentation Skin hyperpigmentation 0% - 14% x x
Metabolic acidosis Metabolic acidosis x x
Areflexia Areflexia x
Decreased vibratory sense Pallanesthesia x
Neurotoxicity Neurotoxicity x
Left ventricular dysfunction Left ventricular dysfunction x x
Sepsis Sepsis x x
Hepatobiliary disease Hepatobiliary disease x x
Toxic neuropathy Toxic neuropathy x
Nephrolithiasis Nephrolithiasis x x
Dysaesthesia Dysaesthesia x
Multifocal motor neuropathy Multifocal motor neuropathy x
Arrhythmia supraventricular Arrhythmia supraventricular x x
Transaminases increased Transaminases increased x x
Coordination abnormal Coordination abnormal x x
Impaired gastric emptying Impaired gastric emptying x x
Hypovolaemia Hypovolaemia x x
Menopausal symptoms Hot flush 0% - 6% x x
Hot flush Hot flush 0% - 6% x x
Infestation Infestation NOS x x
Allodynia Painful response to normal stimuli x
Pancytopenia Myelosuppression x x
Laryngeal pain Pharyngolaryngeal pain x x
Sensorimotor disorder Sensorimotor disorder x
Cardiomyopathy Cardiomyopathy x x
Peripheral sensorimotor neuropathy Peripheral sensorimotor neuropathy x
Respiratory failure Respiratory failure x x
Neutropenic infection Neutropenic infection x x
Ileus Ileus x x
Neuromuscular toxicity Neuromuscular toxicity x
Dysphonia Dysphonia x x
Cerebral haemorrhage Cerebral haemorrhage x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

ixabepilone

Side effects:114
Source:FDA Structured Product Label

IXABEPILONE / IXEMPRA KIT

Side effects:134
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label