Search results :

Amphotericin B

More information: STITCH, PubChem (stereo-specific compounds: 1, 2) and possibly Wikipedia

ATC Codes: A01AB04, A07AA07, G01AA03, J02AA01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Anaemia Anaemia 26.7% - 47.9% x x x x x x
Chills Chills 6% - 89.7% x x x x
Rigors 6% - 89.7% x x x
Hypomagnesaemia Hypomagnesaemia 20.4% - 48.9% x x x x x x x
Blood creatinine increased Creatinine increased 0% - 48.7% x x x x x x
Serum creatinine increased x
Body temperature increased Body temperature increased 7% - 91% x x x
Reaction febrile x
Blood urea increased Blood urea increased 7.4% - 31.1% x x x x x x
Serum urea increased x
Blood alkaline phosphatase increased Phosphatase alkaline increased 19.2% - 22.2% x x x x x x
Headache Headache 19.8% - 20.9% x x x x x x x
Abdominal pain Abdominal pain 7% - 21.8% x x x x x x
Stomach ache x
Gastrointestinal pain Abdominal pain 7% - 21.8% x x x x x x
Hypocalcaemia Hypocalcaemia 12.8% - 20.9% x x x x x x x
Epistaxis Epistaxis 14.9% - 20.1% x x x x x x
Hyperglycaemia Hyperglycaemia 7.58% - 27.9% x x x x x x
Insomnia Insomnia 14.2% - 22.1% x x x x x
Leukopenia Leukopenia 15.1% - 17.2% x x x x x x
Diarrhoea Diarrhoea 3.49% - 30.3% x x x x x x x x
Oedema peripheral Oedema peripheral 14.6% - 17.2% x x x x x
Leg edema x
Constipation Constipation 14.9% - 20.7% x x x x x x
Oedema Oedema 14.3% - 14.8% x x x x x
Dermatitis Rash 4.6% - 24.8% x x x x x x x x
Rash Rash 4.6% - 24.8% x x x x x x x x
Haematuria Haematuria 14% x x x x x
Fluid overload Fluid overload 12.2% - 15.4% x x x x x
Pain Pain 12.8% - 14% x x x x x x
Generalized aching x
Tachycardia Tachycardia 2.33% - 23.1% x x x x x x
Nausea Nausea 0% - 39.7% x x x
Anxiety Anxiety 11% - 13.7% x x x x x x
Asthenia Asthenia 10.8% - 13.1% x x x x x x
Chest pain Chest pain 11.6% - 12% x x x x x x
Retrosternal pain x
Hypokalaemia Hypokalaemia postmarketing, 2.47% - 51.1% x x x x x x x
Decreased appetite Anorexia 9.6% - 14% x x x x x x
Confusional state Confusional state 3.8% - 13.4% x x x x x
Feeling abnormal Confusional state 3.8% - 13.4% x x x x x
Malaise x x x x x
Hypertension Hypertension 2.33% - 23.1% x x x x x x x
Infection Infection 6.9% - 12.8% x x x
Pleural effusion Pleural effusion 9.6% - 12.5% x x x x x
Rhinitis Rhinitis 11% - 11.1% x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 9.9% - 11.3% x x x x x
Phlebitis Phlebitis 9.3% - 25.3% x x x x x x
Pruritus Pruritus 10.2% - 10.8% x x x x x x
Vomiting Vomiting 1.17% - 43.9% x x x
Cough Cough increased 2.1% - 21.8% x x x x x x
Cough x x x
Procedural complication Procedural complication 8.1% - 10.3% x x x
Hyponatraemia Hyponatraemia 8.5% - 11.6% x x x x x x
Liver function test abnormal Liver function test abnormal 4.3% - 12.8% x x x x x x
Hyperhidrosis Sweating 7% - 10.8% x x x x x
Sweating increased x
Dizziness Dizziness 7% - 10.3% x x x x x x
Syncope x x
Hypotension Hypotension 1.23% - 21.5% x x x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia 0% - 19.2% x x x x x x
Hypernatraemia Hypernatraemia 4.1% - 11% x x x x x x
Back pain Back pain common, 7.3% - 12% x x x x x x
Low back pain x
Dyspnoea Dyspnoea 2.47% - 29.1% x x x x x x x
Thrombocytopenia Thrombocytopenia 5.8% - 12.8% x x x x x x x
Sepsis Sepsis 2.35% - 14% x x x x x x
Hypoxia Hypoxia 0.292% - 20.5% x x x x x x
Hypoventilation postmarketing x x x
Lung disorder Lung disorder 0% - 17.8% x x x x x x
Respiratory failure Respiratory failure 1.23% - 5.13% x x x x
Hypoventilation postmarketing x x x
Respiratory insufficiency x x x x
Hyperventilation Hyperventilation 1.17% - 9% x x x x x
Asthma Asthma 1.2% - 5.1% x x x x x
Renal failure acute Renal failure acute 1.23% - 7.69% x x x x x
Agranulocytosis Agranulocytosis postmarketing x x x x
Angioedema Angioedema postmarketing x x x x x
Bronchospasm Bronchospasm postmarketing x x x x x
Cyanosis Cyanosis postmarketing x x x x
Pulmonary oedema Pulmonary oedema postmarketing x x x x x x
Rhabdomyolysis Rhabdomyolysis postmarketing x x
Erythema Erythema postmarketing x x x
Urticaria Urticaria postmarketing x x x x x x
Acute urticaria x
Meningitis cryptococcal Meningitis cryptococcal postmarketing x
Cystitis haemorrhagic Cystitis haemorrhagic postmarketing x x x
Nephropathy toxic Nephrotoxicity postmarketing, 18.7% - 33.7% x x x
Nephropathy toxic x x x x
Hypoventilation Hypoventilation postmarketing x x x
Acidosis Acidosis x x x x x
Renal tubular acidosis Renal tubular acidosis x
Road traffic accident Renal tubular acidosis x
Albuminuria Albuminuria x x x
Respiratory alkalosis Respiratory alkalosis x x x
Alopecia Alopecia x x x x x
Alveolitis allergic Alveolitis allergic x
Amblyopia Amblyopia x x
Anaphylactic shock Anaphylactic shock x x
Anaphylactoid reaction x
Hypochromic anaemia Hypochromic anaemia x x
Anuria Anuria x
Apnoea Apnoea x x
Arrhythmia Arrhythmia x x x x x x x
Arthralgia Arthralgia x x x x x x x
Musculoskeletal discomfort Arthralgia x x x x x x x
Myalgia x x x x x
Atelectasis Atelectasis x x x
Pneumothorax Atelectasis x x x
Atrial fibrillation Atrial fibrillation x x x x x
Coagulopathy Coagulopathy x x x x x x
Candida infection Oral candidiasis x x
Oral candidiasis Oral candidiasis x x
Cardiovascular disorder Cardiovascular disorder x x
Cellulitis Cellulitis x x x
Neck pain Neck pain x x x x x
Cholestasis Cholestasis x
Coma Coma x x x x
Conjunctivitis Conjunctivitis x x x
Connective tissue disorder Connective tissue disorder x
Deafness Deafness x x
Hearing impaired x
Dysphagia Dysphagia x x x
Dehydration Dehydration x x
Diplopia Diplopia x
Dyspepsia Dyspepsia x x x x x x x
Dysuria Dysuria x x x x x
Ear disorder Ear disorder x x
Ecchymosis Ecchymosis x x x x x
Eosinophilia Eosinophilia x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x
Epilepsy Epilepsy x
Eructation Eructation x x x
Extravasation Extravasation x
Eye haemorrhage Eye haemorrhage x x x x x
Faecal incontinence Faecal incontinence x x x x x
Flatulence Flatulence x x x
Flushing Flushing x x x x x
Folliculitis Folliculitis x
Gastroenteritis Gastroenteritis x
Gastrointestinal disorder Gastrointestinal disorder x x
Gingivitis Gingivitis x x
Glossitis Glossitis x x x
Glycosuria Glycosuria x x
Graft versus host disease Graft versus host disease x x x
Hallucination Hallucination x x x x x
Cardiac arrest Cardiac arrest x x x x x x x
Cardiomegaly Cardiomegaly x x x
Cardiac failure Cardiac failure x x
Cardiac failure congestive Cardiac failure congestive x x
Cardiac valve disease Cardiac valve disease x x x
Haematemesis Haematemesis x x x x x
Haemoptysis Haemoptysis x x x x x
Haemorrhage Haemorrhage x x x x x
Haemoglobin Haemorrhage x x x x x
Haemorrhoids Haemorrhoids x x x
Venoocclusive liver disease Venoocclusive liver disease x x x x x x
Hepatitis Hepatitis x
Hepatomegaly Hepatomegaly x x x x
Herpes simplex Herpes simplex x x x
Hiccups Hiccups x x x
Hyperkalaemia Hyperkalaemia x x x x x x x
Hyperlipidaemia Hyperlipidaemia x x
Hypersensitivity Hypersensitivity x x x x x x x
Type IV hypersensitivity reaction Type IV hypersensitivity reaction x x x
Hypoglycaemia Hypoglycaemia x x
Hypoproteinaemia Hypoproteinaemia x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x
Body temperature decreased Body temperature decreased x x
Hypothermia Body temperature decreased x x
Immune system disorder Immune system disorder x x x
Inflammation Inflammation x
Jaundice Jaundice x x x x x
Muscle spasms Cramps of lower extremities x
Cramp muscle x
Pain in extremity Leg pain x
Leukocytosis Leukocytosis x x x
Melaena Melaena x x x
Multi-organ failure Multi-organ failure x
Hypertonia Hypertonia x x
Musculoskeletal pain Musculoskeletal pain x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Nephrocalcinosis Nephrocalcinosis x
Nephrotic syndrome Nephrosis x
Nervousness Nervousness x x x x x
Tension Nervousness x x x x x
Neurosis Neurosis x
Nodule Nodule x
Oliguria Oliguria x x x
Mouth haemorrhage Mouth haemorrhage x x x
Pancreatitis Pancreatitis x
Paraesthesia Paraesthesia x x x x x x
Neuropathy peripheral Neuropathy peripheral x
Neuropathy x x x
Petechiae Petechiae x x x x x
Pharyngitis Pharyngitis x x x x x
Pneumonia Pneumonia x x x
Anal pruritus Anal pruritus x
Pruritus genital Anal pruritus x
Anorectal discomfort Anal pruritus x
Psychotic disorder Psychotic disorder x x
Purpura Purpura x x x
Vascular purpura Purpura x x x
Anorectal disorder Rectal disorder x x x x x
Renal failure Renal failure x x x x x x
Renal impairment x
Convulsion Convulsion x x x x x x x
Shock Shock x x x
Syncope x x
Sinusitis Sinusitis x x x x x
Skin disorder Skin disorder x x x x x
Skin mass Skin nodule x
Skin ulcer Skin ulcer x x x x x
Speech disorder Speech disorder x x
Splenomegaly Splenomegaly x
Erythema multiforme Stevens-Johnson syndrome x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x
Stomatitis Stomatitis x x x x x
Mouth ulceration x x
Mouth ulceration Ulcerative stomatitis x x x
Mouth ulceration x x
Swelling Swelling x
Syncope Syncope x x
Loss of consciousness Syncope x x
Supraventricular tachycardia Supraventricular tachycardia x x
Thrombophlebitis Thrombophlebitis x x
Tinnitus Tinnitus x x x
Tremor Tremor x x x x x x
Azotaemia Uremia x
Azotaemia x
Urinary incontinence Urinary incontinence x x x x x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Angiopathy Angiopathy x x x
Ventricular fibrillation Ventricular fibrillation x
Vertigo Vertigo x
Weight increased Weight increased x x
Weight decreased Weight decreased x x x
Wheezing Wheezing x x
Dry mouth Dry mouth x x x x x
Urinary retention Urinary retention x x
Normochromic normocytic anaemia Normocytic anemia x
Encephalopathy Encephalopathy x
Hepatic failure Hepatic failure x x
Burning sensation Burning sensation x
Stupor Stupor x x
Depressed level of consciousness Stupor x x
Agitation Agitation x x x x x
Hyperchloraemia Hyperchloraemia x x x
Hyperphosphataemia Hyperphosphataemia x x x
Hypophosphataemia Hypophosphataemia x x x x x
Hepatic function abnormal Hepatic function abnormal x
Hepatitis cholestatic Hepatitis cholestatic x
Renal abscess Renal abscess x
Amylase increased Amylase increased x x x
Blood creatine phosphokinase increased Creatine phosphokinase increased x
Diarrhoea haemorrhagic Diarrhoea haemorrhagic x x
Generalised oedema Generalised oedema x x x
Fluid retention Generalised oedema x x x
Ventricular extrasystoles Ventricular extrasystoles x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x x
Pulmonary haemorrhage Pulmonary haemorrhage x
Hypermagnesaemia Hypermagnesaemia x x x
Injection site inflammation Injection site inflammation x x x x
Injection site reaction Injection site reaction x x x
Injury Accidental injury x x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased x x x x x x
Hepatocellular injury Hepatocellular injury x x x x
Liver injury Hepatocellular injury x x x x
Mucous membrane disorder Mucous membrane disorder x x
Bone pain Bone pain x x x x
Injection site pain Injection site pain x x x x
Prothrombin level increased Prothrombin level increased x x x
Rash pustular Vesiculobullous rash x x x x x
Dermatitis bullous Vesiculobullous rash x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x x x
Alanine aminotransferase increased Alanine aminotransferase increased x x
Skin discolouration Skin discolouration x x x x x
Dry skin Dry skin x x x
Tendon disorder Tendon disorder x
Blood thromboplastin decreased Thromboplastin decreased x x
Sensory disturbance Sensory disturbance x
Streptobacillary fever Streptobacillary fever x
Septic arthritis streptobacillus Streptobacillary fever x
Nephrogenic diabetes insipidus Nephrogenic diabetes insipidus x
Malnutrition Malnutrition x x x x x x
Acute hepatic failure Acute hepatic failure x
Abdominal pain upper Stomach ache x
Epigastric pain x
Malaise Malaise x x x x x
Discomfort Malaise x x x x x
Ill-defined disorder Malaise x x x x x
Myalgia Myalgia x x x x x
Tachypnoea Tachypnoea x
Chest discomfort Chest tightness x x x x
Renal impairment Function kidney decreased x x x x
Renal impairment x
Hyposthenuria Hyposthenuria x
Thinking abnormal Thinking abnormal x x
Mental disability Thinking abnormal x x
Rash erythematous Rash erythematous x
Rash follicular Rash follicular x
Neurological symptom Neurological symptom x
Hepatotoxicity Hepatotoxicity x
Hepatic enzyme increased Hepatic enzyme increased x
Skin exfoliation Skin exfoliation x x
Hypoalbuminaemia Hypoalbuminaemia x
Transfusion reaction Transfusion reaction x x
Dry eye Dry eye x x x
Mucosal inflammation Mucosal inflammation x x x
Extrasystoles Extrasystoles x
Anaphylactoid reaction Anaphylactoid reaction x
Abdominal distension Enlargement abdomen x x x x x
Influenza like illness Influenza-like symptoms x x x x
Dysaesthesia Dysaesthesia x x x
Rash maculo-papular Rash maculo-papular x x x x x x
Bradycardia Bradycardia x x x x x x
Application site pain Application site pain x
Instillation site pain Application site pain x
Face oedema Face oedema x x x x x x
Abdominal discomfort Distress gastrointestinal x
Prothrombin level decreased Prothrombin level decreased x x x x x
Blood potassium decreased Serum potassium decreased x
Drug interaction Drug interaction x
Acne Acne x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Blood fibrinogen increased Hyperfibrinogenaemia x x
Hyperfibrinogenaemia Hyperfibrinogenaemia x x
Infusion related reaction Infusion related reaction x x x
Ileus Ileus x x x
Hearing impaired Hearing impaired x
Pelvic haemorrhage Pelvic haemorrhage x
Dysphonia Dysphonia x
Somnolence Somnolence x x x x x
Vaginal haemorrhage Vaginal haemorrhage x x x
Visual impairment Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Amphotericin B / Fungilin, Lozenge

Side effects:9
Source:Medsafe

AMPHOTERICIN B

Side effects:71
Source:FDA Structured Product Label

amphotericin B

Side effects:152
Source:FDA Structured Product Label

AMPHOTERICIN B / AMPHOTEC 100 MG

Side effects:153
Source:Health Canada

AMPHOTERICIN B / AMBISOME

Side effects:162
Source:FDA

AMPHOTERICIN B

Side effects:164
Source:FDA Structured Product Label

AMPHOTERICIN B / AMBISOME FOR INJECTION

Side effects:172
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label