Amphotericin b

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Chills def postmarketing, 3% - 79.5% x x x x x x x
Rigors postmarketing, 6% - 79.5% x x x x x
Hypokalaemia def postmarketing, 6.7% - 26% x x x x x x x
Phlebitis def 9.3% - 25.3% x x x x x x x
Rash def 4.6% - 23.5% x x x x x x x
Nausea def postmarketing, 4% - 20% x x x x x x x
Hyperbilirubinaemia def postmarketing, 2% - 19% x x x x x
Vomiting def postmarketing, 4% - 18% x x x x x x x
Haematuria def 14% x x x x x
Tachycardia def postmarketing, 2.33% - 12.5% x x x x x
Hypotension def 3.5% - 12% x x x x x x x
Hypertension def 2.33% - 11.3% x x x x x x x
Liver function test abnormal 4% - 11% x x x x
Cough def 2.1% - 10.3% x x x x x
Cough increased 2.1% - 10.3% x x x x x
Dyspnoea def postmarketing, 4% - 9% x x x x x x x
Hypoxia def 0.292% - 9% x x x x x
Headache def postmarketing, 4% - 8% x x x x x x x
Thrombocytopenia def postmarketing, 1% - 7% x x x x x x x
Fever chills postmarketing, 3% - 7% x x x x
Hypomagnesaemia def postmarketing, 4% - 7% x x x x x x x
Phosphatase alkaline increased 3% - 7% x x x x
Hyperglycaemia def 1% - 6% x x x x x
Vasodilation def 0.581% - 5.25% x x x x x
Hyperventilation def 1.17% - 4.94% x x x x x
Acidosis def postmarketing x x x x x x x
Renal tubular acidosis def postmarketing x x
Agranulocytosis def postmarketing x x x x x
Alveolitis allergic def postmarketing x x
Anaphylactic shock def postmarketing x
Anaemia def postmarketing x x x x x x x
Angioedema def postmarketing x x x
Anorexia def postmarketing x x x x x x x
Anuria def postmarketing x x
Coagulopathy def postmarketing x x x x x x x
Bronchospasm def postmarketing x x x x
Cholestasis def postmarketing x
Convulsion def postmarketing x x x x x x x
Cyanosis def postmarketing x x x
Cystitis def postmarketing x x x
Diabetes insipidus def postmarketing x x
Diabetes mellitus def postmarketing x x
Diplopia def postmarketing x x
Oedema def postmarketing x x x x x x x
Eosinophilia def postmarketing x x
Epilepsy def postmarketing x
Extravasation def postmarketing x x
Gastroenteritis def postmarketing x x
Haemorrhage def postmarketing x x x x x
Hyperkalaemia def postmarketing x x x x x x x
Hypersensitivity def postmarketing x x x x x x x
Hypocalcaemia def postmarketing x x x x x x
Infarction def postmarketing x
Jaundice def postmarketing x x x x x
Renal failure acute def postmarketing x x x x x
Leukocytosis def postmarketing x x x x
Leukopenia def postmarketing x x x x x x x
Melaena def postmarketing x x x x
Myocardial infarction def postmarketing x
Oliguria def postmarketing x x x x
Pain def postmarketing x x x x x x x
Neuropathy peripheral def postmarketing x x
Pneumonia def postmarketing x x x x x
Pulmonary oedema def postmarketing x x x x x x x
Renal failure def postmarketing x x x x x x x
Gastric disorder def postmarketing x
Sweating def postmarketing x x x x x
Swelling def postmarketing x
Thrombophlebitis def postmarketing x x
Tinnitus def postmarketing x x x x
Erythema def postmarketing x x x
Urticaria def postmarketing x x x x
Vertigo def postmarketing x x
Wheezing def postmarketing x x
Encephalopathy def postmarketing x x
Hepatic failure def postmarketing x x x x
Cystitis haemorrhagic postmarketing x x x
Generalised oedema postmarketing x x x
Renal tubular disorder def postmarketing x x
Retrosternal pain postmarketing x
Nephrogenic diabetes insipidus def postmarketing x x
Acute hepatic failure def postmarketing x x
Stomach ache def postmarketing x
Malaise def postmarketing x x x x x
Neurological symptom postmarketing x x
Reaction febrile postmarketing x x
Normochromic anemia postmarketing x
Hepatic enzyme increased postmarketing x
Vision blurred def postmarketing x
Hypoventilation def postmarketing x x x
Neuropathy def postmarketing x x x x
Serum potassium decreased postmarketing x
Organ failure postmarketing x
Hearing impaired def postmarketing x x
Abdominal pain def x x x x x
Albuminuria def x x
Alkalosis def x x x
Respiratory alkalosis def x x x
Alopecia def x x x x x
Amblyopia def x x
Hypochromic anaemia def x x
Anxiety def x x x x x
Apnoea def x x
Arrhythmia def x x x x x x x
Arthralgia def x x x x x x x
Asthenia def x x x x x
Asthma def x x x x x
Atelectasis def x x x
Atrial fibrillation def x x x x x
Back pain def x x x x x
Cardiovascular disorder def x x
Cellulitis def x x x
Neck pain def x x x x x
Chest pain def x x x x x
Coma def x x x
Confusional state def x x x x x
Conjunctivitis def x x x
Constipation def x x x x x
Deafness def x x
Dysphagia def x x x
Dehydration def x x
Diarrhoea def x x x x x x x
Dizziness def x x x x x
Dyspepsia def x x x x x x x
Dysuria def x x x x x
Ear disorder def x x
Ecchymosis def x x x x x
Effusion def x x x x x
Toxic epidermal necrolysis def x x
Epistaxis def x x x x x
Eructation def x x x
Eye haemorrhage def x x x x x
Faecal incontinence def x x x x x
Flatulence def x x x
Flushing def x x x x x
Gastrointestinal disorder def x x
Gastrointestinal haemorrhage def x x x x x
Gingivitis def x x
Glossitis def x x
Glycosuria def x x
Graft versus host disease def x x x
Hallucination def x x x x x
Cardiac arrest def x x x x x x x
Cardiac disorder def x x x
Cardiomegaly def x x x
Cardiac failure def x x x x
Cardiac failure congestive def x x
Cardiac valve disease def x x x
Haematemesis def x x x x x
Haemoptysis def x x x x x
Haemorrhoids def x x x
Venoocclusive liver disease def x x
Hepatitis def x
Hepatomegaly def x x x
Herpes NOS def x x x
Herpes simplex def x x x
Hiccups def x x x
HIV infection def x x x
Hyperlipidaemia def x x
Hypernatraemia def x x x x x
Type IV hypersensitivity reaction def x x
Hypoglycaemia def x x
Hyponatraemia def x x x x x
Hypoproteinaemia def x x x x x
Orthostatic hypotension def x x x x x
Body temperature decreased def x x
Immune system disorder def x x
Incontinence def x x x x x
Inflammation def x x x x x
Influenza def x x x
Nephropathy def x x x
Liver disorder def x x x x x
Lung disorder def x x x x x
Cramp muscle def x x
Hypertonia def x x
Nephrocalcinosis def x x
Nervousness def x x x x x
Nodule def x
Mouth haemorrhage def x x x
Paraesthesia def x x x x x
Petechiae def x x x x x
Pharyngitis def x x x x x
Pleural disorder def x x x x x
Pleural effusion def x x x x x
Pruritus def x x x x x x x
Psychotic disorder def x x
Purpura def x x x
Rectal disorder def x x x x x
Respiratory disorder def x x
Respiratory insufficiency def x x x
Rhinitis def x x x x x
Shock def x x x x
Sinusitis def x x x x x
Skin disorder def x x x x x
Skin nodule def x
Skin ulcer def x x x x
Speech disorder def x x
Stomatitis def x x x x x
Ulcerative stomatitis x x x
Progressive supranuclear palsy def x
Syncope def x x
Supraventricular tachycardia def x x
Ulcer def x x x x x
Urinary incontinence def x x x x x
Urinary tract disorder def x x
Angiopathy def x x x
Ventricular fibrillation def x x
Visual impairment def x
Weight increased def x x
Weight decreased def x x x x
Dry mouth def x x x x x
Urinary retention def x x
Normocytic anemia x x
Stupor def x x
Agitation def x x x x x
Oedema peripheral def x x x x x
Hyperchloraemia x x x
Hyperphosphataemia def x x
Hypophosphataemia def x x x x x
Mouth ulceration def x x
Amylase increased x x x
Blood urea increased x x x x x
Diarrhoea haemorrhagic x x
Necrolysis epidermal x x
Ventricular extrasystoles def x x
Gamma-glutamyltransferase increased def x x
Hypermagnesaemia x x x
Injection site inflammation x x x x
Injection site reaction def x x x
Kidney function abnormal x x x x x
Lactic dehydrogenase activity increased x x x x x
Hepatocellular injury x x x
Mucous membrane disorder x x
Bone pain def x x x
Injection site pain x x x x
Prothrombin level increased x x x
Vesiculobullous rash x x x x
Aspartate aminotransferase increased def x
Alanine aminotransferase increased def x
Skin discolouration def x x x x x
Dry skin def x x x
Thromboplastin decreased x x
Myalgia def x x x x x
Tachypnoea def x
Cardiac fibrillation x x x x x x x
Chest tightness x x x
Epigastric pain x x
Function kidney decreased x x x x x
Hyposthenuria x x
Thinking abnormal x x
Vein pain x
Skin exfoliation x x
Microscopic hematuria x
Azotaemia def x x
Sepsis def x x x x x
Transfusion reaction x x x
Generalized aching x x
Dry eye x x x
Mucosal inflammation def x x x
Extrasystoles def x x
Enlargement abdomen def x x x x x
Dysaesthesia def x x x
Dystonia def x x x
Rash maculo-papular def x x x x x x
Prolonged menses x
Casts urinary hyaline x
Bradycardia def x x x x x
Face oedema def x x x x x
Fluid overload def x x x x x
Prothrombin level decreased x x x x x
Nephropathy toxic x x x
Drug interaction def x
Acne def x x
Empiric treatment x x x
Insomnia def x x x x x
Hyperfibrinogenemia x x
Infusion related reaction def x x x
Pain during injection x x
Respiratory failure def x x x
Ileus def x x x
Death x x
Somnolence def x x x x x
Vaginal haemorrhage def x x x
Indication Labels
Adverse event def x x
Adverse reaction def x x
Aspergillosis def x x x x x x
Auditory recruitment x x
Blastomycosis def x x
Blood disorder def x x
Body temperature increased def x x
Candidiasis def x x x x
Coccidioidomycosis def x
Creatinine increased def x
Cryptococcosis def x x x x
Discomfort def x
Fungal infection def x x x x x
Histoplasmosis def x x
HIV test positive def x x x
Infection def x x x x x
Insufficiency renal def x x x
Leishmaniasis def x x x x
Meningitis def x x x
Meningitis cryptococcal def x x x
Mucocutaneous leishmaniasis def x
Mucormycosis def x x
Oesophageal candidiasis x
Oesophageal disorder def x
Oral candidiasis def x
Paracoccidioides infection def x
Renal impairment def x x x x
Sporotrichosis def x x
Systemic candida x x
Tremor def x
Vaginal moniliasis x
Visceral leishmaniasis def x x
Zygomycosis def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: A01AB04, A07AA07, G01AA03, J02AA01

Legend

Color scheme: standardalternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. AMPHOTERICIN B : 88 side effects (FDA XML label)
  2. AMPHOTERICIN B / FUNGIZONE INTRAVENOUS INJECTION 50MG : 90 side effects (Health Canada)
  3. AMPHOTERICIN B / AMPHOTEC 100 MG : 161 side effects (Health Canada)
  4. amphotericin B : 166 side effects (FDA XML label)
  5. AMPHOTERICIN B / AMBISOME : 169 side effects (Drugs@FDA)
  6. AMPHOTERICIN B / AMBISOME : 170 side effects (Drugs@FDA)
  7. AMPHOTERICIN B / AMBISOME FOR INJECTION : 184 side effects (Health Canada)