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Amphotericin B

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: A01AB04, A07AA07, G01AA03, J02AA01

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Anemia 26.7% - 47.9% x x x x x x
Chills 6% - 89.7% x x x x
Hypomagnesaemia 20.4% - 48.9% x x x x x x x
Rigor - Temperature-associated observation 6% - 89.7% x x x
Creatinine increased 0% - 48.7% x x x x x x
Fever 7% - 91% x x x
Blood urea increased 7.4% - 31.1% x x x x x x
Alkaline phosphatase raised 19.2% - 22.2% x x x x x x
Headache 19.8% - 20.9% x x x x x x x
Abdominal Pain 7% - 21.8% x x x x x x
Hypocalcemia 12.8% - 20.9% x x x x x x x
Epistaxis 14.9% - 20.1% x x x x x x
Sleeplessness 14.2% - 22.1% x x x x x
Hyperglycemia 7.58% - 27.9% x x x x x x
Leukopenia 15.1% - 17.2% x x x x x x
Diarrhea 3.49% - 30.3% x x x x x x x x
Peripheral edema 14.6% - 17.2% x x x x x
Constipation 14.9% - 20.7% x x x x x x
Edema 14.3% - 14.8% x x x x x
Exanthema 4.6% - 24.8% x x x x x x x x
Hematuria 14% x x x x x
Fluid overload 12.2% - 15.4% x x x x x
Pain 12.8% - 14% x x x x x x
Nausea 0% - 39.7% x x x
Tachycardia 2.3% - 23.1% x x x x x x
Anxiety 11% - 13.7% x x x x x x
Asthenia 10.8% - 13.1% x x x x x x
Chest Pain 11.6% - 12% x x x x x x
Hypokalemia postmarketing, 2.47% - 51.1% x x x x x x x
Anorexia 9.6% - 14% x x x x x x
Confusion 3.8% - 13.4% x x x x x
Hypertensive disease 2.3% - 23.1% x x x x x x x
Communicable Diseases 6.9% - 12.8% x x x
Rhinitis 11% - 11.1% x x x x x
Pleural effusion disorder 9.6% - 12.5% x x x x x
Gastrointestinal Hemorrhage 9.9% - 11.3% x x x x x
Phlebitis 9% - 25.3% x x x x x x
Pruritus 10.2% - 10.8% x x x x x x
Vomiting 1.17% - 43.9% x x x
Cough increased 2.1% - 21.8% x x x x x x
Procedural complication 8.1% - 10.3% x x x
Liver function tests abnormal finding 4.3% - 12.8% x x x x x x
Hyponatremia 8.5% - 11.6% x x x x x x
Sweating 7% - 10.8% x x x x x
Dizziness 7% - 10.3% x x x x x x
Hypotension 1.23% - 21.5% x x x x x x x
Hyperbilirubinemia 0% - 19.2% x x x x x x
Hypernatremia 4.1% - 11% x x x x x x
Back Pain common, 7.3% - 12% x x x x x x
Dyspnea 2.47% - 29.1% x x x x x x x
Thrombocytopenia 5.8% - 12.8% x x x x x x x
Sepsis 2.35% - 14% x x x x x x
Hypoxia 0.292% - 20.5% x x x x x x
Lung diseases 0% - 17.8% x x x x x x
Respiratory Failure 1.23% - 5.13% x x x x
Hyperventilation 1.17% - 9% x x x x x
Asthma 1.2% - 5.1% x x x x x
Kidney Failure, Acute 1.23% - 7.69% x x x x x
Meningitis, Cryptococcal postmarketing x
Rhabdomyolysis postmarketing x x
Erythema postmarketing x x x
Pulmonary Edema postmarketing x x x x x x
Cystitis haemorrhagic postmarketing x x x
Bronchial Spasm postmarketing x x x x x
Nephrotoxicity postmarketing, 18.7% - 33.7% x x x
Hypoventilation postmarketing x x x
Urticaria postmarketing x x x x x x
Angioedema postmarketing x x x x x
Agranulocytosis postmarketing x x x x
Cyanosis postmarketing x x x x
Hemorrhoids x x x
Anaphylactoid reaction x
Amblyopia x x
Body Weight decreased x x x
Hypothermia, natural x x
Creatine phosphokinase increased x
Swelling x
Atrial Fibrillation x x x x x
Dryness of eye x x x
Herpes Simplex Infections x x x
Increased sweating x
Liver Failure x x
Tendon disorder x
Icterus x x x x x
Hypersensitivity x x x x x x x
Hepatic Veno-Occlusive Disease x x x x x x
Supraventricular tachycardia x x
Prothrombin level increased x x x
Enlargement abdomen x x x x x
Drug Interactions x
Peeling of skin x x
Extravasation x
Hallucinations x x x x x
Hypotension, Orthostatic x x x x x
Alopecia x x x x x
Hypermagnesemia x x x
Tinnitus x x x
Bradycardia x x x x x x
Vascular Diseases x x x
Hepatitis cholestatic x
Pain in lower limb x
Deglutition Disorders x x x
Azotemia x
Anuria x
Amylase increased x x x
Arthralgia x x x x x x x
Stomatitis x x x x x
Eye Hemorrhage x x x x x
Hypoproteinemia x x x x x
Urologic Diseases x x
Pancreatitis x
Hyperlipidemia x x
Hypophosphatemia x x x x x
Rash maculo-papular x x x x x x
Kidney Failure x x x x x x
Dysesthesia x x x
Normocytic anemia x
Burning sensation x
Connective Tissue Diseases x
Encephalopathies x
Hypoglycemia x x
Stomach ache x
Nodule x
Pharyngitis x x x x x
Immune System Diseases x x x
Splenomegaly x
Tachypnea x
Stevens-Johnson Syndrome x x
Cardiac Arrest x x x x x x x
Inflammation x
Coughing x x x
Nephrosis x
Nervousness x x x x x
Epilepsy x
Hypochromic anemia x x
Cardiovascular Diseases x x
Hemoptysis x x x x x
Multiple Organ Failure x
Skin Ulcer x x x x x
Gastrointestinal Diseases x x
Epigastric pain x
hearing impairment x
Myalgia x x x x x
Acute urticaria x
Lactic dehydrogenase activity increased x x x x x x
Comatose x x x x
Dysphonia x
Thrombophlebitis x x
Nephropathy toxic x x x x
Nephrocalcinosis x
Gamma-glutamyltransferase increased x x
Muscle Cramp x
Visual Impairment x
Pulmonary hemorrhage x
Nephrogenic Diabetes Insipidus x
Injection site inflammation x x x x
Vaginal Hemorrhage x x x
Ventricular Fibrillation x
Mucositis x x x
Injection site pain x x x x
Speech Disorders x x
Premature Cardiac Complex x
Vertigo x
Hyperchloraemia x x x
Purpura x x x
Cardiac Arrhythmia x x x x x x x
Neuropathy x x x
Injection site reaction x x x
Hemorrhage x x x x x
Delayed Hypersensitivity x x x
Liver Dysfunction x
Dermatologic disorders x x x x x
Psychotic Disorders x x
Fecal Incontinence x x x x x
Accidental injury x x
Glycosuria x x
Transfusion Reaction x x
Serum potassium decreased x
Acidosis x x x x x
Vesiculobullous rash x x x x x
Reaction febrile x
Diplopia x
Congestive heart failure x x
Renal abscess x
Uremia x
Apnea x x
Cholestasis x
Blood Coagulation Disorders x x x x x x
Alkalosis, Respiratory x x x
Distress gastrointestinal x
Low Back Pain x
Hyperfibrinogenaemia x x
Eosinophilia x
Application site pain x
Hyposthenuria x
Diarrhoea haemorrhagic x x
Dehydration x x
Leg edema x
Function kidney decreased x x x x
Liver Failure, Acute x
Neurologic Symptoms x
Deafness x x
Cardiomegaly x x x
Hepatitis x
Hyperuricemia x
Alanine aminotransferase increased x x
Folliculitis x
Peripheral Neuropathy x
Bone pain x x x x
Syncope x x
Glossitis x x x
Streptobacillary fever x
Urinary Incontinence x x x x x
anaphylaxis x x
Pruritus Ani x
Ecchymosis x x x x x
Malnutrition x x x x x x
Oral candidiasis x x
Hepatomegaly x x x x
Stupor x x
Ileus x x x
Flushing x x x x x
HIV Infections x x x
Pelvic haemorrhage x
Hematemesis x x x x x
Agitation x x x x x
Rash erythematous x
Anasarca x x x
Tremor x x x x x x
Serum urea increased x
Disease of mucous membrane x x
Ear Diseases x x
Thromboplastin decreased x x
Prothrombin level decreased x x x x x
Aspartate aminotransferase increased x x x x
Paresthesia x x x x x x
Somnolence x x x x x
Gastroenteritis x
Dyspepsia x x x x x x x
Leukocytosis x x x
Urinary Retention x x
Oliguria x x x
Neurotic Disorders x
Petechiae x x x x x
Eructation x x x
Heart valve disease x x x
Flatulence x x x
Hyperphosphatemia (disorder) x x x
Extrinsic allergic alveolitis x
Respiration Disorders x x x
Conjunctivitis x x x
Generalized aches and pains x
Pneumonia x x x
Sinusitis x x x x x
Wheezing x x
Serum creatinine increased x
Liver damage x x x x
Malaise x x x x x
Disturbance in thinking x x
Cramps of lower extremities x
Hiccup x x x
Atelectasis x x x
Infusion related reaction x x x
Hypoalbuminemia x
Hepatotoxicity x
Weight Gain x x
Oral Ulcer x x
Cellulitis x x x
Toxic Epidermal Necrolysis x x
Gingivitis x x
Heart failure x x
Renal tubular acidosis x
Graft-vs-Host Disease x x x
Dry skin x x x
Discoloration of skin x x x x x
Chest tightness x x x x
Shock x x x
Renal Insufficiency x
Rash follicular x
Hyperkalemia x x x x x x x
Albuminuria x x x
Rectal Diseases x x x x x
Ulcerative stomatitis x x x
Muscle Hypertonia x x
Retrosternal pain x
Melena x x x
Sensory Disorders x
Dysuria x x x x x
Skin nodule x
Acne x
Xerostomia x x x x x
Premature ventricular contractions x x
Seizures x x x x x x x
Hepatic enzyme increased x
Facial edema x x x x x x
Influenza-like symptoms x x x x
Myocardial Infarction x
Musculoskeletal Pain x
Respiratory Insufficiency x x x x
Oral Hemorrhage x x x
Neck Pain x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Amphotericin B / Fungilin, Lozenge

Side effects:9
Source:Medsafe

AMPHOTERICIN B

Side effects:71
Source:FDA Structured Product Label

amphotericin B

Side effects:153
Source:FDA Structured Product Label

AMPHOTERICIN B / AMPHOTEC 100 MG

Side effects:154
Source:Health Canada

AMPHOTERICIN B / AMBISOME

Side effects:163
Source:FDA

AMPHOTERICIN B

Side effects:165
Source:FDA Structured Product Label

AMPHOTERICIN B / AMBISOME FOR INJECTION

Side effects:173
Source:Health Canada

Color scheme:

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    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label