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Amphotericin B

More information: STITCH, PubChem (stereo-specific compounds: 1, 2) and possibly Wikipedia

ATC Codes: A01AB04, A07AA07, G01AA03, J02AA01

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Anaemia 26.7% - 47.9% x x x x x x
Chills 6% - 89.7% x x x x
Hypomagnesaemia 20.4% - 48.9% x x x x x x x
Rigors 6% - 89.7% x x x
Creatinine increased 0% - 48.7% x x x x x x
Body temperature increased 7% - 91% x x x
Blood urea increased 7.4% - 31.1% x x x x x x
Phosphatase alkaline increased 19.2% - 22.2% x x x x x x
Headache 19.8% - 20.9% x x x x x x x
Abdominal pain 7% - 21.8% x x x x x x
Hypocalcaemia 12.8% - 20.9% x x x x x x x
Epistaxis 14.9% - 20.1% x x x x x x
Hyperglycaemia 7.58% - 27.9% x x x x x x
Insomnia 14.2% - 22.1% x x x x x
Leukopenia 15.1% - 17.2% x x x x x x
Diarrhoea 3.49% - 30.3% x x x x x x x x
Oedema peripheral 14.6% - 17.2% x x x x x
Constipation 14.9% - 20.7% x x x x x x
Oedema 14.3% - 14.8% x x x x x
Rash 4.6% - 24.8% x x x x x x x x
Haematuria 14% x x x x x
Fluid overload 12.2% - 15.4% x x x x x
Pain 12.8% - 14% x x x x x x
Tachycardia 2.33% - 23.1% x x x x x x
Nausea 0% - 39.7% x x x
Anxiety 11% - 13.7% x x x x x x
Asthenia 10.8% - 13.1% x x x x x x
Chest pain 11.6% - 12% x x x x x x
Hypokalaemia postmarketing, 2.47% - 51.1% x x x x x x x
Anorexia 9.6% - 14% x x x x x x
Confusional state 3.8% - 13.4% x x x x x
Hypertension 2.33% - 23.1% x x x x x x x
Infection 6.9% - 12.8% x x x
Pleural effusion 9.6% - 12.5% x x x x x
Rhinitis 11% - 11.1% x x x x x
Gastrointestinal haemorrhage 9.9% - 11.3% x x x x x
Phlebitis 9.3% - 25.3% x x x x x x
Pruritus 10.2% - 10.8% x x x x x x
Vomiting 1.17% - 43.9% x x x
Cough increased 2.1% - 21.8% x x x x x x
Procedural complication 8.1% - 10.3% x x x
Hyponatraemia 8.5% - 11.6% x x x x x x
Liver function test abnormal 4.3% - 12.8% x x x x x x
Sweating 7% - 10.8% x x x x x
Dizziness 7% - 10.3% x x x x x x
Hypotension 1.23% - 21.5% x x x x x x x
Hyperbilirubinaemia 0% - 19.2% x x x x x x
Hypernatraemia 4.1% - 11% x x x x x x
Back pain common, 7.3% - 12% x x x x x x
Dyspnoea 2.47% - 29.1% x x x x x x x
Thrombocytopenia 5.8% - 12.8% x x x x x x x
Sepsis 2.35% - 14% x x x x x x
Hypoxia 0.292% - 20.5% x x x x x x
Lung disorder 0% - 17.8% x x x x x x
Respiratory failure 1.23% - 5.13% x x x x
Hyperventilation 1.17% - 9% x x x x x
Asthma 1.2% - 5.1% x x x x x
Renal failure acute 1.23% - 7.69% x x x x x
Agranulocytosis postmarketing x x x x
Angioedema postmarketing x x x x x
Bronchospasm postmarketing x x x x x
Cyanosis postmarketing x x x x
Pulmonary oedema postmarketing x x x x x x
Rhabdomyolysis postmarketing x x
Erythema postmarketing x x x
Urticaria postmarketing x x x x x x
Meningitis cryptococcal postmarketing x
Cystitis haemorrhagic postmarketing x x x
Nephrotoxicity postmarketing, 18.7% - 33.7% x x x
Hypoventilation postmarketing x x x
Acidosis x x x x x
Renal tubular acidosis x
Albuminuria x x x
Respiratory alkalosis x x x
Alopecia x x x x x
Alveolitis allergic x
Amblyopia x x
Anaphylactic shock x x
Hypochromic anaemia x x
Anuria x
Apnoea x x
Arrhythmia x x x x x x x
Arthralgia x x x x x x x
Atelectasis x x x
Atrial fibrillation x x x x x
Coagulopathy x x x x x x
Oral candidiasis x x
Cardiovascular disorder x x
Cellulitis x x x
Neck pain x x x x x
Cholestasis x
Coma x x x x
Conjunctivitis x x x
Connective tissue disorder x
Cough x x x
Deafness x x
Dysphagia x x x
Dehydration x x
Diplopia x
Dyspepsia x x x x x x x
Dysuria x x x x x
Ear disorder x x
Ecchymosis x x x x x
Eosinophilia x
Toxic epidermal necrolysis x x
Epilepsy x
Eructation x x x
Extravasation x
Eye haemorrhage x x x x x
Faecal incontinence x x x x x
Flatulence x x x
Flushing x x x x x
Folliculitis x
Gastroenteritis x
Gastrointestinal disorder x x
Gingivitis x x
Glossitis x x x
Glycosuria x x
Graft versus host disease x x x
Hallucination x x x x x
Cardiac arrest x x x x x x x
Cardiomegaly x x x
Cardiac failure x x
Cardiac failure congestive x x
Cardiac valve disease x x x
Haematemesis x x x x x
Haemoptysis x x x x x
Haemorrhage x x x x x
Haemorrhoids x x x
Venoocclusive liver disease x x x x x x
Hepatitis x
Hepatomegaly x x x x
Herpes simplex x x x
Hiccups x x x
Hyperkalaemia x x x x x x x
Hyperlipidaemia x x
Hypersensitivity x x x x x x x
Type IV hypersensitivity reaction x x x
Hypoglycaemia x x
Hypoproteinaemia x x x x x
Orthostatic hypotension x x x x x
Body temperature decreased x x
Immune system disorder x x x
Inflammation x
Jaundice x x x x x
Cramps of lower extremities x
Leg pain x
Leukocytosis x x x
Low back pain x
Melaena x x x
Multi-organ failure x
Cramp muscle x
Hypertonia x x
Musculoskeletal pain x
Myocardial infarction x
Nephrocalcinosis x
Nephrosis x
Nervousness x x x x x
Neurosis x
Nodule x
Oliguria x x x
Mouth haemorrhage x x x
Pancreatitis x
Paraesthesia x x x x x x
Neuropathy peripheral x
Petechiae x x x x x
Pharyngitis x x x x x
Pneumonia x x x
Anal pruritus x
Psychotic disorder x x
Purpura x x x
Rectal disorder x x x x x
Renal failure x x x x x x
Respiratory insufficiency x x x x
Convulsion x x x x x x x
Shock x x x
Sinusitis x x x x x
Skin disorder x x x x x
Skin nodule x
Skin ulcer x x x x x
Speech disorder x x
Splenomegaly x
Stevens-Johnson syndrome x x
Stomatitis x x x x x
Ulcerative stomatitis x x x
Swelling x
Syncope x x
Supraventricular tachycardia x x
Thrombophlebitis x x
Tinnitus x x x
Tremor x x x x x x
Uremia x
Urinary incontinence x x x x x
Urinary tract disorder x x
Angiopathy x x x
Ventricular fibrillation x
Vertigo x
Weight increased x x
Weight decreased x x x
Wheezing x x
Dry mouth x x x x x
Urinary retention x x
Normocytic anemia x
Encephalopathy x
Hepatic failure x x
Burning sensation x
Stupor x x
Agitation x x x x x
Hyperchloraemia x x x
Hyperphosphataemia x x x
Hypophosphataemia x x x x x
Hepatic function abnormal x
Mouth ulceration x x
Hepatitis cholestatic x
Renal abscess x
Amylase increased x x x
Creatine phosphokinase increased x
Diarrhoea haemorrhagic x x
Generalised oedema x x x
Ventricular extrasystoles x x
Gamma-glutamyltransferase increased x x
Pulmonary haemorrhage x
Hypermagnesaemia x x x
Injection site inflammation x x x x
Injection site reaction x x x
Accidental injury x x
Lactic dehydrogenase activity increased x x x x x x
Hepatocellular injury x x x x
Mucous membrane disorder x x
Bone pain x x x x
Retrosternal pain x
Injection site pain x x x x
Prothrombin level increased x x x
Vesiculobullous rash x x x x x
Aspartate aminotransferase increased x x x x
Alanine aminotransferase increased x x
Skin discolouration x x x x x
Dry skin x x x
Tendon disorder x
Thromboplastin decreased x x
Sensory disturbance x
Streptobacillary fever x
Nephrogenic diabetes insipidus x
Malnutrition x x x x x x
Acute hepatic failure x
Stomach ache x
Malaise x x x x x
Myalgia x x x x x
Tachypnoea x
Chest tightness x x x x
Epigastric pain x
Function kidney decreased x x x x
Hyposthenuria x
Thinking abnormal x x
Rash erythematous x
Rash follicular x
Acute urticaria x
Neurological symptom x
Hepatotoxicity x
Reaction febrile x
Leg edema x
Hepatic enzyme increased x
Skin exfoliation x x
Hypoalbuminaemia x
Azotaemia x
Transfusion reaction x x
Generalized aching x
Dry eye x x x
Mucosal inflammation x x x
Extrasystoles x
Anaphylactoid reaction x
Enlargement abdomen x x x x x
Influenza-like symptoms x x x x
Dysaesthesia x x x
Rash maculo-papular x x x x x x
Bradycardia x x x x x x
Neuropathy x x x
Application site pain x
Face oedema x x x x x x
Distress gastrointestinal x
Prothrombin level decreased x x x x x
Serum potassium decreased x
Nephropathy toxic x x x x
Drug interaction x
Serum creatinine increased x
Sweating increased x
Acne x
Hyperuricaemia x
Serum urea increased x
Hyperfibrinogenaemia x x
Infusion related reaction x x x
Ileus x x x
Hearing impaired x
Pelvic haemorrhage x
Dysphonia x
Renal impairment x
Somnolence x x x x x
Vaginal haemorrhage x x x
Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Amphotericin B / Fungilin, Lozenge

Side effects:9
Source:Medsafe

AMPHOTERICIN B

Side effects:71
Source:FDA Structured Product Label

amphotericin B

Side effects:152
Source:FDA Structured Product Label

AMPHOTERICIN B / AMPHOTEC 100 MG

Side effects:153
Source:Health Canada

AMPHOTERICIN B / AMBISOME

Side effects:162
Source:FDA

AMPHOTERICIN B

Side effects:164
Source:FDA Structured Product Label

AMPHOTERICIN B / AMBISOME FOR INJECTION

Side effects:172
Source:Health Canada

Color scheme:

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    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label