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Procarbazine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XB01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Metastatic neoplasm Metastatic neoplasm <1-15% x
Pulmonary toxicity Pulmonary toxicity 1% x x
Abdominal pain Abdominal pain x x x
Gastrointestinal pain Abdominal pain x x x
Alopecia Alopecia x x x
Amenorrhoea Amenorrhoea x
Anaemia Anaemia x x x
Haemolytic anaemia Haemolytic anaemia x x x
Angina pectoris Angina pectoris x x
Decreased appetite Anorexia x x x
Arrhythmia Arrhythmia x
Arthralgia Arthralgia x x x
Musculoskeletal discomfort Arthralgia x x x
Myalgia x x x
Ascites Ascites x x
Asthenia Asthenia x x x
Fatigue x x x
Ataxia Ataxia x x x
Azoospermia Azoospermia x x x
Neoplasm malignant Neoplasm malignant x x x
Coma Coma x x x
Infection Infection x x x
Confusional state Confusional state x x x
Feeling abnormal Confusional state x x x
Constipation Constipation x x x
Cough Cough x x x
Dysphagia Dysphagia x x x
Dermatitis Dermatitis x x x
Rash x x x
Diarrhoea Diarrhoea x x x
Diplopia Diplopia x x x
Dizziness Dizziness x x x
Syncope x x x
Somnolence Drowsiness x x x
Oedema Oedema x x x
Eosinophilia Eosinophilia x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x
Epistaxis Epistaxis x x x
Rash Rash x x x
Fatigue Fatigue x x x
Body temperature increased Body temperature increased x x x
Flushing Flushing x x x
Gynaecomastia Gynaecomastia x x x
Hallucination Hallucination x x x
Headache Headache x x x
Haematemesis Haematemesis x x x
Haematuria Haematuria x x x
Haemoptysis Haemoptysis x x x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Herpes virus infection Herpes NOS x x x
Dysphonia Hoarseness x x x
Hypersensitivity Hypersensitivity x x x
Type IV hypersensitivity reaction Type IV hypersensitivity reaction x
Hypertension Hypertension x x
Hypotension Hypotension x x x
Infertility Infertility x
Jaundice Jaundice x x
Lethargy Lethargy x x
Acute myeloid leukaemia Acute myeloid leukaemia x x x
Acute leukaemia Acute myeloid leukaemia x x x
Leukopenia Leukopenia x x x
Lymphocytosis Lymphocytosis x
Melaena Melaena x x x
Menopause Menopause x
Nausea Nausea x x x
Nephritis Nephritis x x
Nervousness Nervousness x x x
Tension Nervousness x x x
Nightmare Nightmare x x x
Nocturia Nocturia x x x
Nystagmus Nystagmus x x x
Osteonecrosis Osteonecrosis x x
Pain Pain x x x
Pancreatitis Pancreatitis x x
Pancytopenia Pancytopenia x x x
Optic neuritis Papilloedema x x x
Papilloedema Papilloedema x x x
Paraesthesia Paraesthesia x x x
Pericarditis Pericarditis x x
Petechiae Petechiae x x x
Pleural effusion Pleural effusion x x x
Pneumonia Pneumonia x x x
Pruritus Pruritus x x x
Purpura Purpura x x x
Vascular purpura Purpura x x x
Raynaud's phenomenon Raynaud's disease x x
Retinal haemorrhage Retinal haemorrhage x x x
Convulsion Convulsion x x x
Stomatitis Stomatitis x x x
Hyperhidrosis Sweating x
Sweating increased x x x
Shock Syncope x x x
Syncope Syncope x x x
Loss of consciousness Syncope x x x
Tachycardia Tachycardia x x x
Thrombocytopenia Thrombocytopenia x x x
Thrombosis Thrombosis x x
Tremor Tremor x x x
Pollakiuria Pollakiuria x x x
Urticaria Urticaria x x x
Vomiting Vomiting x x x
Dry mouth Dry mouth x x x
Chills Chills x x x
Photophobia Photophobia x x x
Peroneal nerve palsy Footdrop x x
Hepatic function abnormal Hepatic function abnormal x x x
Hyporeflexia Hyporeflexia x x x
Lung cancer metastatic Lung cancer metastatic x x
Skin hyperpigmentation Skin hyperpigmentation x x x
Anisocytosis Anisocytosis x
Poikilocytosis Poikilocytosis x
Myalgia Myalgia x x x
Disorientation Disorientation x
Anxiety Apprehension x x x
Dysarthria Slurred speech x x x
Photosensitivity reaction Photosensitivity x x
Balance disorder Unsteadiness x x x
Neuropathy peripheral Neuropathy x x x
Lung neoplasm malignant Carcinoma of lung x x
Febrile neutropenia Febrile neutropenia x
Ovarian failure Ovarian failure x x
Cardiotoxicity Cardiotoxicity x x
Insomnia Insomnia x x x
Deafness Hearing impaired x x x
Hearing impaired Hearing impaired x x x
Haemorrhagic disorder Bleeding tendency x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PROCARBAZINE

Side effects:85
Source:FDA Structured Product Label

PROCARBAZINE (PROCARBAZINE HYDROCHLORIDE) / MATULANE

Side effects:100
Source:Health Canada

Procarbazine

Side effects:105
Source:BC Cancer

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label