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Vandetanib

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4
Nausea Nausea 1% - 33.3% 0% - 16.2% x x x x
Headache Headache 1% - 26% 0% - 9.09% x x x x
Acne Acne 1% - 35% 0% - 7% x x x
Dermatitis acneiform Dermatitis acneiform 1% - 35% 0% - 7% x x x
Dry skin Dry skin 0% - 15.2% 0% - 5.05% x x x x
Amylase increased Serum amylase increased 5% - 23.8% x x
Electrocardiogram QT prolonged Electrocardiogram QT prolonged 8% - 14.3% 1% - 1.01% x x x
Electrocardiogram QT corrected interval prolonged x
Insomnia Insomnia 13% 10.1% x x x
Decreased appetite Decreased appetite 1.73% - 21.2% 0% - 12.1% x x x x
Haemoglobin increased Haemoglobin increased 12.1% 0% x x
Upper respiratory tract infection Upper respiratory tract infection 0% - 23% 0% - 16% x x
Nasopharyngitis Nasopharyngitis 11.3% 9.09% x x x
Colitis Colitis 0.4% - 57% 2% - 27% x x x x
Diarrhoea Diarrhoea 0.9% - 57% 0% - 27% x x x x
Cough Cough 10.8% 10.1% x x
Dyspepsia Dyspepsia 0% - 11% 0% - 4.04% x x x x
Weight decreased Weight decreased 10.4% 9.09% x x x
Hypertension Hypertension 0.9% - 33% 0% - 5.05% x x x x
Malignant hypertension Malignant hypertension 0.4% - 33% 1% - 5% x x x
Hypertensive crisis Hypertensive crisis 1.73% - 33% 0% - 5% x x x x
Abdominal pain Abdominal pain 1.3% - 21% 0% - 11% x x x x
Gastrointestinal pain Abdominal pain 1.3% - 21% 0% - 11% x x x x
Alopecia Alopecia 8% 0% x x x
Vomiting Vomiting 0.9% - 15% 0% - 7.07% x x x x
Photosensitivity reaction Photosensitivity reaction 0.9% - 13.4% 0% x x x x
Hypocalcaemia Hypocalcaemia 0.9% - 11% 0% - 3.03% x x x x
Asthenia Fatigue 0.4% - 24% 1% - 23.2% x x x x
Asthenia 0.4% - 14.7% 11.1% x x x x
Fatigue Fatigue 0.4% - 24% 1% - 23.2% x x x x
Pruritus Pruritus 0.4% - 11% 0% - 4.04% x x x x
Dermatitis Rash 0.4% - 53% 0% - 12% x x x x
Dermatitis x
Rash Rash 0.4% - 53% 0% - 12% x x x x
Proteinuria Proteinuria 0% - 10% 0% - 2% x x x
Protein urine present Proteinuria 0% - 10% 0% - 2% x x x
Dry mouth Dry mouth 0% - 9% 0% - 3% x x
Nail disorder Nail abnormality NOS 0% - 9% 0% x
Nail disorder x x
Dysgeusia Dysgeusia 0% - 8% 0% - 3% x x
Hypothyroidism Hypothyroidism 0% - 6% 0% x x
Muscle spasms Muscle spasms 0% - 6% 0% - 1% x
Depression Depression 1.3% - 10% 0% - 3% x x x x
Pneumonia Pneumonia 0.9% - 2.16% 0% x x x
Hypercalcaemia Hypercalcaemia 1.3% 0% x x
Ca++ increased x
Urinary tract infection Urinary tract infection 1.3% 0% x x
Gastroenteritis Gastroenteritis 1% x
Appendicitis Appendicitis 0.9% x x
Bronchitis Bronchitis 0.9% x x
Transient ischaemic attack Transient ischaemic attack 0.9% x
Dysphagia Dysphagia 0.9% x x
Dehydration Dehydration 0.9% x x
Diverticulitis Diverticulitis 0.9% x x
Body temperature increased Body temperature increased 0.9% x x x
Hypokalaemia Hypokalaemia 0.9% x x
Loss of consciousness Loss of consciousness 0.9% x x
Blood creatinine increased Creatinine increased 0.9% x x x
Blood creatinine increased x
Serum creatinine increased x
Sepsis Sepsis 0.9% x x x
Nephrolithiasis Nephrolithiasis 0.9% x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 0.4% - 1% x x x
Anuria Anuria 0.4% x x
Arrhythmia Arrhythmia 0.4% x x
Atrial fibrillation Atrial fibrillation 0.4% x
Bipolar disorder Bipolar disorder 0.4% x
Bipolar I disorder Bipolar disorder 0.4% x
Bronchospasm Bronchospasm 0.4% x
Chest pain Chest pain 0.4% x
Cholecystitis Cholecystitis 0.4% x
Cholelithiasis Cholelithiasis 0.4% x x
Chylothorax Chylothorax 0.4% x
Dyspnoea Dyspnoea 0.4% x
Gastritis Gastritis 0.4% x x
Glaucoma Glaucoma 0.4% x x
Haemoptysis Haemoptysis 0.4% x x
Hypoglycaemia Hypoglycaemia 0.4% x x
Hyponatraemia Hyponatraemia 0.4% x x
Laryngitis Laryngitis 0.4% x x
Pericarditis Pericarditis 0.4% x
Peritonitis Peritonitis 0.4% x x
Pneumonia aspiration Pneumonia aspiration 0.4% x x x
Pyelonephritis Pyelonephritis 0.4% x x
Renal failure Renal failure 0.4% x x
Skin ulcer Skin ulcer 0.4% x
Staphylococcal infection Staphylococcal infection 0.4% x
Tracheitis Tracheitis 0.4% x
Tubulointerstitial nephritis Tubulointerstitial nephritis 0.4% x
Small intestinal perforation Small intestinal perforation 0.4% x
Renal colic Renal colic 0.4% x
Viral diarrhoea Viral diarrhoea 0.4% x
Staphylococcal bacteraemia Staphylococcal bacteraemia 0.4% x
Bone cancer metastatic Bone cancer metastatic 0.4% x
Respiratory arrest Respiratory arrest 0.4% x x
Malnutrition Malnutrition 0.4% x x x
Abdominal wall abscess Abdominal wall abscess 0.4% x x
Cardiac failure acute Cardiac failure acute 0.4% x x
Vena cava thrombosis Vena cava thrombosis 0.4% x
Mucosal inflammation Mucosal inflammation 0.4% x
Vision blurred Vision blurred 0% - 9% 0% - 1% x x x x
Joint injury Joint injury 0.4% x
Bradycardia Bradycardia 0.4% x
Altered state of consciousness Depressed level of consciousness 0.4% x
Depressed level of consciousness Depressed level of consciousness 0.4% x
Pelvic venous thrombosis Pelvic venous thrombosis 0.4% x
Infected bites Infected bites 0.4% x
General physical health deterioration General physical health deterioration 0.4% x
Cerebral ischaemia Cerebral ischaemia 0.4% x
Device occlusion Stent occlusion 0.4% x
Peripheral sensorimotor neuropathy Peripheral sensorimotor neuropathy 0.4% x
Pneumatosis intestinalis Pneumatosis intestinalis 0.4% x
Respiratory failure Respiratory failure 0.4% x x x
Ileus Ileus 0.4% x x
Venomous bite Venomous bite 0.4% x
Calculus ureteric Calculus ureteric 0.4% x
Brain oedema Brain oedema 0.4% x x
Anxiety Anxiety x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Mental disorder Mental disorder x x x
Cellulitis Cellulitis x
Clonus Clonus x
Infection Infection x x x
Conjunctivitis Conjunctivitis x
Constipation Constipation x
Corneal opacity Corneal opacity x x x x
Cystitis Cystitis x
Bladder pain Cystitis x
Cystitis noninfective Cystitis x
Cyst Cyst x
Sudden death Sudden death x
Dizziness Dizziness x
Dysuria Dysuria x
Oedema Oedema x
Endocrine disorder Endocrine disorder x x
Epistaxis Epistaxis x
Erythema multiforme Erythema multiforme x x
Stevens-Johnson syndrome x x x
Eye disorder Eye disorder x x x
Faecal incontinence Faecal incontinence x
Folliculitis Folliculitis x
Gastrointestinal disorder Gastrointestinal disorder x x x
Cardiac arrest Cardiac arrest x
Cardiac disorder Cardiac disorder x x
Cardiac failure Cardiac failure x x x
Haematuria Haematuria x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Hyperglycaemia Hyperglycaemia x
Influenza Influenza x
Intestinal perforation Intestinal perforation x x
Nephropathy Nephropathy x
Lethargy Lethargy x
Mediastinal disorder Mediastinal disorder x x
Musculoskeletal disorder Musculoskeletal disorder x
Fungal infection Fungal infection x
Neoplasm Neoplasm x
Nervous system disorder Nervous system disorder x x
Neutropenia Neutropenia x x
Pain Pain x
Pancreatitis Pancreatitis x x x x
Paraesthesia Paraesthesia x
Polyp Polyp x
Convulsion Convulsion x
Sinusitis Sinusitis x
Skin disorder Skin disorder x x
Unspecified disorder of skin and subcutaneous tissue x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x
Stomatitis Stomatitis x
Thrombocytopenia Thrombocytopenia x
Torsade de pointes Torsade de pointes x x x
Tremor Tremor x
Pollakiuria Pollakiuria x
Micturition urgency x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Angiopathy Angiopathy x x x
Micturition urgency Micturition urgency x
Ventricular arrhythmia Ventricular arrhythmia x
Photopsia Photopsia x
Dermatitis bullous Dermatitis bullous x
Cataract Cataract x
Impaired healing Impaired healing x
Hypomagnesaemia Hypomagnesaemia x
Alanine aminotransferase increased Alanine aminotransferase increased x x
Haemoglobin decreased Haemoglobin decreased x
Corneal deposits Corneal deposits x
Interstitial lung disease Interstitial lung disease x x
Visual acuity reduced Visual acuity reduced x x
Keratopathy Keratopathy x
Blood magnesium decreased Mg reduced x
Blood magnesium increased Mg++ increased x
Furuncle Furuncle x
Conduction disorder Conduction disorder x
Hepatobiliary disease Hepatobiliary disease x x
Blood bilirubin increased Blood bilirubin increased x
Dry eye Dry eye x
Platelet count decreased Platelet count decreased x
Dysaesthesia Dysaesthesia x
Halo vision Halo vision x
Chromaturia Chromaturia x
Gastroenteritis bacterial Gastroenteritis bacterial x
Balance disorder Balance disorder x
Cardio-respiratory arrest Cardio-respiratory arrest x
White blood cell count decreased White blood cell count decreased x
Infestation Infestation NOS x
Alanine aminotransferase normal Alanine aminotransferase normal x
Blood potassium increased Potassium increased x
Blood glucose decreased Glucose low x
Glucose decreased x
Blood glucose increased Glucose increased x
Blood potassium decreased Potassium low x
Blood calcium decreased Calcium low x
Posterior reversible encephalopathy syndrome Posterior reversible encephalopathy syndrome x x
Visual impairment Visual impairment x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

VANDETANIB

Side effects:59
Source:FDA Structured Product Label

VANDETANIB

Side effects:62
Source:FDA Structured Product Label

Vandetanib / CAPRELSA

Side effects:121
Source:medicines.org.au

vandetanib / vandetanib

Side effects:125
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label