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ATC Code: L01XX01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Blood bilirubin increased Blood bilirubin increased 30% x x
Anaemia Anaemia 1-10% x x
Confusional state Confusional state 1-10% x x
Feeling abnormal Confusional state 1-10% x x
Dizziness Dizziness 1-10% x
Headache Headache 1-10% x
Paraesthesia Paraesthesia 1-10% x
Convulsion Convulsion 1-10% x x
Vision blurred Vision blurred 1-10% x
Arrhythmia Arrhythmia 1% x x
Hypersensitivity Hypersensitivity 0.4% x x
Abdominal pain Abdominal pain x x
Gastrointestinal pain Abdominal pain x x
Agranulocytosis Agranulocytosis x x
Alopecia Alopecia x x
Aplastic anaemia Aplastic anaemia x
Decreased appetite Anorexia x x
Asthenia Asthenia x
Fatigue x
Atrial fibrillation Atrial fibrillation x x
Mental disorder Mental disorder x
Infection Infection x x
Connective tissue disorder Connective tissue disorder x
Dysphagia Dysphagia x x
Diarrhoea Diarrhoea x x
Dyspnoea Dyspnoea x x
Dermatitis Rash x x
Rash Rash x x
Extravasation Extravasation x
Fatigue Fatigue x
Body temperature increased Body temperature increased x x
Gastrointestinal disorder Gastrointestinal disorder x
Gingival bleeding Gingival bleeding x
Gingivitis Gingivitis x x
Cardiac disorder Cardiac disorder x
Cardiac failure congestive Cardiac failure congestive x x
Haematemesis Haematemesis x x
Haematuria Haematuria x x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Hepatitis Hepatitis x x
Hypoaesthesia Hypoaesthesia x
Hypotension Hypotension x x
Inflammation Inflammation x x
Jaundice Jaundice x
Lethargy Lethargy x
Leukopenia Leukopenia x x
Mediastinal disorder Mediastinal disorder x
Musculoskeletal pain Musculoskeletal pain x x
Nausea Nausea x x
Necrosis Necrosis x
Pain Pain x
Pancytopenia Pancytopenia x
Bone marrow depression x
Myelosuppression x x
Phlebitis Phlebitis x x
Proteinuria Proteinuria x x
Protein urine present Proteinuria x x
Purpura Purpura x x
Vascular purpura Purpura x x
Renal failure Renal failure x x
Stomatitis Stomatitis x x
Tachycardia Tachycardia x x
Sinus tachycardia Sinus tachycardia x x
Thrombocytopenia Thrombocytopenia x x
Ureteric obstruction Ureteric obstruction x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x x
Angiopathy Angiopathy x
Ventricular fibrillation Ventricular fibrillation x
Vomiting Vomiting x x
Weight increased Weight increased x
Weight decreased Weight decreased x
Hepatic failure Hepatic failure x x
Hepatic insufficiency x x
Ventricular arrhythmia Ventricular arrhythmia x x
Mood swings Mood swings x
Affect lability Mood swings x
Blood urea increased Blood urea increased x x
Blood creatinine increased Creatinine increased x x
Hypomagnesaemia Hypomagnesaemia x
Injection site inflammation Injection site inflammation x
Injection site reaction Injection site reaction x
Blood alkaline phosphatase increased Phosphatase alkaline increased x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Hepatotoxicity Hepatotoxicity x
Sepsis Sepsis x x
Aplasia Aplasia x
Perirectal abscess Perirectal abscess x x
Hepatobiliary disease Hepatobiliary disease x
Mucosal inflammation Mucosal inflammation x x
Bradycardia Bradycardia x x
Chromaturia Urine color abnormal x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Ejection fraction decreased Ejection fraction decreased x
Febrile neutropenia Febrile neutropenia x
Infestation Infestation NOS x
Cardiomyopathy Cardiomyopathy x x
Urine output Urine output x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:69
Source:BC Cancer


Side effects:75
Source:Health Canada

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label