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More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX01

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2
Blood bilirubin increased 30% x x
Anaemia 1-10% x x
Confusional state 1-10% x x
Dizziness 1-10% x
Headache 1-10% x
Paraesthesia 1-10% x
Convulsion 1-10% x x
Vision blurred 1-10% x
Arrhythmia 1% x x
Hypersensitivity 0.4% x x
Abdominal pain x x
Agranulocytosis x x
Alopecia x x
Aplastic anaemia x
Anorexia x x
Asthenia x
Atrial fibrillation x x
Mental disorder x
Infection x x
Connective tissue disorder x
Dysphagia x x
Diarrhoea x x
Dyspnoea x x
Rash x x
Extravasation x
Fatigue x
Body temperature increased x x
Gastrointestinal disorder x
Gingival bleeding x
Gingivitis x x
Cardiac disorder x
Cardiac failure congestive x x
Haematemesis x x
Haematuria x x
Haemorrhage x x
Hepatitis x x
Hypoaesthesia x
Hypotension x x
Inflammation x x
Jaundice x
Lethargy x
Leukopenia x x
Mediastinal disorder x
Musculoskeletal pain x x
Nausea x x
Necrosis x
Pain x
Pancytopenia x
Phlebitis x x
Proteinuria x x
Purpura x x
Renal failure x x
Stomatitis x x
Tachycardia x x
Sinus tachycardia x x
Thrombocytopenia x x
Ureteric obstruction x
Urinary tract disorder x
Urticaria x x
Angiopathy x
Ventricular fibrillation x
Vomiting x x
Weight increased x
Weight decreased x
Hepatic failure x x
Ventricular arrhythmia x x
Mood swings x
Blood urea increased x x
Creatinine increased x x
Hypomagnesaemia x
Injection site inflammation x
Injection site reaction x
Bone marrow depression x
Phosphatase alkaline increased x x
Aspartate aminotransferase increased x
Malnutrition x
Unspecified disorder of skin and subcutaneous tissue x
Hepatotoxicity x
Sepsis x x
Aplasia x
Perirectal abscess x x
Hepatobiliary disease x
Mucosal inflammation x x
Bradycardia x x
Urine color abnormal x
Hyperuricaemia x
Ejection fraction decreased x
Febrile neutropenia x
Infestation NOS x
Blood and lymphatic system disorders x
Myelosuppression x x
Cardiomyopathy x x
Urine output x
Hepatic insufficiency x x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:69
Source:BC Cancer


Side effects:75
Source:Health Canada

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label