Search results :

Tobramycin

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: J01GB01, S01AA12

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14
Cough Cough increased 46.1% 47.3% x
Cough very common, 31.1% - 48.4% x x
Pharyngitis Pharyngitis 38% 39.3% x
Sputum increased Sputum increased 37.6% 39.7% x
Increased bronchial secretion Sputum increased 37.6% 39.7% x
Asthenia Asthenia 35.7% 39.3% x x x x
Rhinitis Rhinitis 34.5% 33.6% x
Dyspnoea Dyspnoea very common, 12.4% - 33.7% 38.5% x x x
Body temperature increased Body temperature increased very common, 12.4% - 32.9% 43.5% x x x x x x x x x x
Lung disorder Lung disorder 30.1% - 33.8% 31.3% x x x
Headache Headache uncommon, 11.4% - 26.7% 32.1% x x x x x x x
Chest pain Chest pain 26% 29.8% x
Chest discomfort common, 2.9% - 6.5% x x
Haemoptysis Haemoptysis very common, 12.4% - 19.4% 23.7% x x x
Decreased appetite Anorexia 18.6% 27.9% x
Productive cough Productive cough very common, 18.2% - 19.6% x x
Respiratory depression Respiratory depression rare, 16.3% 15.3% x x x x
Pulmonary function test decreased Respiratory depression rare, 16.3% 15.3% x x x x
Pulmonary function test decreased 6.8% - 8.1% x
Asthma Asthma 15.9% 20.2% x
Renal impairment Function kidney decreased very common x
Vomiting Vomiting common, 5.7% - 14% 22.1% x x x x x x x x x x
Abdominal pain Abdominal pain 12.8% 23.7% x
Gastrointestinal pain Abdominal pain 12.8% 23.7% x
Oropharyngeal pain Oropharyngeal pain 10.5% - 14% x x x
Nausea Nausea common, 7.5% - 11.2% 16% x x x x x x x x x x
Weight decreased Weight decreased 10.1% 15.3% x
Dysphonia Dysphonia very common, 3.8% - 13.6% 1.74% x x x
Red blood cell sedimentation rate increased Red blood cell sedimentation rate increased 8.42% 5.22% x
Pain Pain very common, 8.1% 12.6% x x x x x
Stinging x
Sinusitis Sinusitis 8.1% 9.2% x
Upper respiratory tract infection Upper respiratory tract infection 6.8% - 8.6% x
Ear pain Ear pain 7.4% 8.8% x
Nasal congestion Nasal congestion common, 7.2% - 8.1% x x
Back pain Back pain 7% 8% x
Rales Rales common, 6.2% - 18.9% 15.7% x x x
Dysgeusia Dysgeusia common, 0.5% - 6.6% 6.9% x x x
Malaise Malaise 6.2% 5.3% x
Discomfort Malaise 6.2% 5.3% x
Feeling abnormal Malaise 6.2% 5.3% x
Confusional state x x x
Ill-defined disorder Malaise 6.2% 5.3% x
Epistaxis Epistaxis common, 1.9% - 7% 0% - 6.5% x x x x
Dizziness Dizziness common, 5.8% 7.6% x x x x x x x x
Lower respiratory tract infection Lower respiratory tract infection 5.8% 8% x
Wheezing Wheezing common, 5.26% - 6.8% 3.48% x x x
Diarrhoea Diarrhoea common, 1.58% - 6.2% 0.87% - 10.3% x x x x x x x x x x x
Hyperventilation Hyperventilation 5.4% 9.9% x
Dermatitis Rash rare — 2.3% - 5.4% 6.1% x x x x x x x x x x x
Dermatitis uncommon x
Rash Rash rare — 2.3% - 5.4% 6.1% x x x x x x x x x x x
Bronchospasm Bronchospasm common x x x
Deafness High frequency deafness common x x x
Hearing impaired postmarketing, common x x
Deafness x
Vertigo Vertigo common x x x x x x x
Endophthalmitis Ocular hyperaemia common x
Ocular hyperaemia Ocular hyperaemia common x
Chest discomfort Chest discomfort common, 2.9% - 6.5% x x
Ocular discomfort Ocular discomfort common x
Musculoskeletal chest pain Musculoskeletal chest pain common, 4.5% - 4.8% x x
Throat irritation Throat irritation common, 1.9% - 4.5% x x
Forced expiratory volume decreased Forced expiratory volume decreased 1% - 31.1% 28.7% x x
Bronchitis Bronchitis 2.63% 0.87% x
Laryngeal pain Pharyngolaryngeal pain 2.63% 1.74% x x x
Aphonia Aphonia postmarketing, common x x x
Tonsillitis Tonsillitis 2.11% 0% x
Blood glucose increased Blood glucose increased 0.5% - 2.9% x
Eosinophilia Eosinophilia 1.58% 0% x x x x x x x
Immunoglobulins increased Immunoglobulins increased 1.58% 0% x
Conjunctival disorder Conjunctival disorder uncommon x
Corneal abrasion Corneal abrasion uncommon x
Eyelid disorder Eyelid disorder uncommon x
Hypersensitivity Hypersensitivity uncommon x x x x x x x
Eye pruritus Eye pruritus uncommon x
Keratitis Keratitis uncommon x
Pruritus Pruritus uncommon x x x x x x x x x x x
Tinnitus Tinnitus postmarketing — common x x x x x x x x x x x
Ear roaring x x x x x x x
Urticaria Urticaria uncommon x x x x x x x x x
Conjunctival oedema Conjunctival oedema uncommon x
Eye pain Eye pain uncommon x
Dry skin Dry skin uncommon x
Lacrimation increased Lacrimation increased uncommon x
Lacrimation x x
Eyelid oedema Eyelid oedema uncommon x
Leukoderma Leukoderma uncommon x
Erythema of eyelid Erythema of eyelid uncommon x
Madarosis Madarosis uncommon x
Dry eye Dry eye uncommon x
Vision blurred Vision blurred uncommon x
Eye discharge Eye discharge uncommon x
Blood creatinine increased Serum creatinine increased uncommon x x
Creatinine increased x
Foreign body sensation in eyes Foreign body sensation in eyes uncommon x
Visual impairment Visual impairment uncommon x
Anaphylactic shock Anaphylactic shock rare x x x
Renal failure acute Renal failure acute rare x
Tubulointerstitial nephritis Nephritis interstitial rare x
Nervous system disorder Nervous system disorder postmarketing x x x
Ototoxicity Ototoxicity postmarketing, rare x x x x x x
Cochlear toxicity x
Nephropathy toxic Nephrotoxicity rare x
Nephropathy toxic x
Hearing impaired Hearing impaired postmarketing, common x x
Deafness unilateral x
Agranulocytosis Agranulocytosis x x x x x x x
Anaemia Anaemia x x x x x x x
Angioedema Angioedema x x x
Apnoea Apnoea x x x
Bone disorder Bone disorder x
Confusional state Confusional state x x x
Connective tissue disorder Connective tissue disorder x x
Dehydration Dehydration x x x
Delirium Delirium x x x
Dermatitis exfoliative Dermatitis exfoliative x x x x x x x
Eye disorder Eye disorder x
Gastrointestinal disorder Gastrointestinal disorder x x
Hypocalcaemia Hypocalcaemia x x x
Hypokalaemia Hypokalaemia x x x
Immune system disorder Immune system disorder x x
Laryngitis Laryngitis x
Lethargy Lethargy x x x x x x x
Leukocytosis Leukocytosis x x x
Leukopenia Leukopenia x x x
Mediastinal disorder Mediastinal disorder x x x x
Oliguria Oliguria x x x x x x x
Paraesthesia Paraesthesia x x x
Neuropathy peripheral Neuropathy peripheral x x x
Proteinuria Proteinuria x x x x x x
Protein urine present Proteinuria x x x x x x
Renal failure Renal failure x
Stomatitis Stomatitis x x x
Swelling Swelling x x x
Thrombocytopenia Thrombocytopenia x x x x x x x
Thrombophlebitis Thrombophlebitis x x
Erythema Erythema x x x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x x
Hypophosphataemia Hypophosphataemia x x x
Hypomagnesaemia Hypomagnesaemia x x x
Muscular weakness Muscular weakness x x x
Injection site pain Injection site pain x x x
Blood alkaline phosphatase increased Phosphatase alkaline increased x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x
Hypouricaemia Hypouricaemia x x x
Myalgia Myalgia x
Musculoskeletal discomfort Myalgia x
Disorientation Disorientation x x x
Neurotoxicity Neurotoxicity x x x x x x x
Eye irritation Eye irritation x
Blood creatinine decreased Creatinine low x
Hypoalbuminaemia Hypoalbuminaemia x x x
Punctate keratitis Punctate keratitis x
Platelet count decreased Platelet count decreased x x x
Rash maculo-papular Rash maculo-papular x x x
Application site pain Application site pain x x x
Instillation site pain Application site pain x x x
Metabolic syndrome Metabolic syndrome x x x
Blood calcium decreased Serum calcium decreased x x x
Drug interaction Drug interaction x x x
Eyelids pruritus Eyelids pruritus x
Infestation Infestation NOS x x
Eye allergy Eye allergy x
Local reaction Local reaction x
Blood bilirubin increased Serum bilirubin increased x
Transaminases increased Serum transaminase increased x x x
Ocular toxicity Ocular toxicity x x x
Deafness unilateral Deafness unilateral x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

tobramycin / Tobrex

Side effects:5
Source:FDA

TOBRAMYCIN / TOBREX 0.3% OPHTHALMIC SOL

Side effects:6
Source:Health Canada

TOBRAMYCIN

Side effects:16
Source:FDA Structured Product Label

tobramycin / tobramycin

Side effects:32
Source:EMA

TOBRAMYCIN

Side effects:40
Source:FDA Structured Product Label

Tobramycin

Side effects:50
Source:FDA Structured Product Label

TOBRAMYCIN SULFATE / TOBRAMYCIN SULFATE

Side effects:29
Source:FDA

TOBRAMYCIN

Side effects:30
Source:FDA Structured Product Label

TOBRAMYCIN

Side effects:30
Source:FDA Structured Product Label

Tobramycin BP / TOBRAMYCIN PF

Side effects:44
Source:medicines.org.au

TOBRAMYCIN INJECTION

Side effects:45
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label