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Cabozantinib

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Prehypertension Prehypertension 34% 54% x
Lymphopenia Lymphopenia 11% - 53% 51% x x
Hypocalcaemia Hypocalcaemia 3% - 52% 27% x x
Asthenia Fatigue 3% - 41% 28% x x
Asthenia 1% - 21% 15% x x
Fatigue Fatigue 3% - 41% 28% x x
Hypertension Hypertension 0% - 33% 4% x x
Alanine aminotransferase increased Alanine aminotransferase increased 2% - 86% 41% x x
Hyperbilirubinaemia Hyperbilirubinaemia 2% - 25% 14% x x
Stomatitis Stomatitis 0% - 51% 6% x x
Weight decreased Weight decreased 0% - 48% 10% x x
Decreased appetite Decreased appetite 1% - 46% 16% x x
Dysphagia Dysphagia 1% - 13% 6% x x
Hypokalaemia Hypokalaemia 3% - 18% 9% x
Abdominal pain Abdominal pain 1% - 27% 13% x x
Gastrointestinal pain Abdominal pain 1% - 27% 13% x x
Neutropenia Neutropenia 2% - 35% 15% x x
Thrombocytopenia Thrombocytopenia 0% - 35% 4% x x
Hypophosphataemia Hypophosphataemia 1% - 28% 10% x x
Blood alkaline phosphatase increased Phosphatase alkaline increased 3% - 52% 35% x x
Aspartate aminotransferase increased Aspartate aminotransferase increased 2% - 86% 35% x x
Dehydration Dehydration 1% - 7% 2% x x
Hyponatraemia Hyponatraemia 0% - 10% 5% x
Vomiting Vomiting 1% - 24% 2% x x
Oral pain Oral pain 0% - 36% 6% x
Arthralgia Arthralgia 0% - 14% 7% x x
Musculoskeletal discomfort Arthralgia 0% - 14% 7% x x
Dermatitis Rash 0% - 19% 10% x x
Rash Rash 0% - 19% 10% x x
Hypotension Hypotension 0% - 7% 0% x x
Nausea Nausea 0% - 43% 21% x x
Erythema Erythema 0% - 11% 2% x x
Hypomagnesaemia Hypomagnesaemia 0% - 19% 4% x
Musculoskeletal chest pain Musculoskeletal chest pain 0% - 9% 4% x x
Abscess Abscess x
Alopecia Alopecia 0% - 16% 2% x x
Amenorrhoea Amenorrhoea x
Angina pectoris Angina pectoris x
Anxiety Anxiety 0% - 9% 2% x x
Ataxia Ataxia x
Atelectasis Atelectasis x
Pneumothorax Atelectasis x
Atrial fibrillation Atrial fibrillation x
Mental disorder Mental disorder x x
Blister Blister x
Dermatitis bullous Blister x
Breast disorder Breast disorder x
Transient ischaemic attack Transient ischaemic attack x
Cheilitis Cheilitis x
Cholelithiasis Cholelithiasis x
Infection Infection x
Confusional state Confusional state x
Feeling abnormal Confusional state x
Conjunctivitis Conjunctivitis x
Connective tissue disorder Connective tissue disorder x x
Constipation Constipation 0% - 27% 6% x x
Delirium Delirium x
Diarrhoea Diarrhoea x x
Dizziness Dizziness 0% - 14% 7% x x
Dysgeusia Dysgeusia 0% - 34% 6% x x
Dyspepsia Dyspepsia 0% - 11% 0% x x
Dysuria Dysuria x
Ear pain Ear pain x
Localised oedema Localised oedema x
Endocrine disorder Endocrine disorder x
Oesophagitis Oesophagitis x
Eye disorder Eye disorder x
Facial pain Facial pain x
Anal fissure Anal fissure x
Fistula Fistula x
Folliculitis Folliculitis x
Gastrointestinal disorder Gastrointestinal disorder x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Glossodynia Glossodynia x
Headache Headache 0% - 18% 8% x x
Cardiac arrest Cardiac arrest x
Cardiac disorder Cardiac disorder x
Haematuria Haematuria x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Haemorrhoids Haemorrhoids 0% - 9% 3% x x
Hepatic encephalopathy Hepatic encephalopathy x
Malignant hypertension Malignant hypertension x
Hypothyroidism Hypothyroidism x
Renal failure acute Renal failure acute x
Mediastinal disorder Mediastinal disorder x x
Pneumomediastinum Pneumomediastinum x
Fungal infection Fungal infection x
Nervous system disorder Nervous system disorder x x
Pallor Pallor x
Pancreatitis Pancreatitis x x
Paraesthesia Paraesthesia 0% - 7% 2% x x
Neuropathy peripheral Neuropathy peripheral 0% - 5% 0% x x
Pneumonia Pneumonia x x
Pneumonia aspiration Pneumonia aspiration x
Proteinuria Proteinuria x x
Protein urine present Proteinuria x x
Pulmonary embolism Pulmonary embolism x
Rhabdomyolysis Rhabdomyolysis x
Sepsis Septicemia x
Skin ulcer Skin ulcer x
Muscle spasms Muscle spasms 0% - 12% 5% x x
Speech disorder Speech disorder x
Supraventricular tachycardia Supraventricular tachycardia x
Telangiectasia Telangiectasia x
Tinnitus Tinnitus x
Tremor Tremor x
Loss of consciousness Loss of consciousness x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x x
Venous thrombosis Venous thrombosis x
Wound Wound x
Chills Chills x
Cataract Cataract x
Peripheral sensory neuropathy Peripheral sensory neuropathy 0% - 7% 0% x
Gastrointestinal perforation Gastrointestinal perforation x
Impaired healing Impaired healing x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased x
Dry skin Dry skin 0% - 19% 3% x x
Arterial thrombosis Arterial thrombosis x
Malnutrition Malnutrition x x
Leukoderma Leukoderma 0% - 34% 1% x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x
Hair growth abnormal Hair growth abnormal x
Disturbance in attention Disturbance in attention x
Abnormal dreams Abnormal dreams x
Respiratory tract haemorrhage Respiratory tract haemorrhage x
Pharyngeal oedema Pharyngeal oedema x
Anal inflammation Anal inflammation x
Disease progression Disease progression x
Hepatobiliary disease Hepatobiliary disease x
Aspergilloma Aspergilloma x
Peripheral coldness Peripheral coldness x
Mucosal inflammation Mucosal inflammation x
Tracheal fistula Tracheal fistula x
Gastrointestinal fistula Gastrointestinal fistula x
Vision blurred Vision blurred x
Hair colour changes Hair colour changes 0% - 34% 1% x x
Blood pressure increased Blood pressure increased x
Face oedema Face oedema x
Lipase increased Lipase increased x
Blood thyroid stimulating hormone increased Thyrotropin high x
Thrombocytosis Thrombocytosis x
Infestation Infestation NOS x
Activated partial thromboplastin time shortened Activated partial thromboplastin time shortened x
Neutrophil count decreased Neutrophil count decreased x
Embolism Thromboembolic event x
Hyperkeratosis Hyperkeratosis 0% - 7% 0% x x
Respiratory failure Respiratory failure x
Deafness Hearing impaired x
Hearing impaired Hearing impaired x
Dysphonia Dysphonia 0% - 20% 9% x x
Eosinophil count increased Eosinophil count increased x
Oropharyngeal pain Oropharyngeal pain x
Ageusia Ageusia x
Osteonecrosis of jaw Osteonecrosis of jaw x x
Vaginal haemorrhage Vaginal haemorrhage x
Posterior reversible encephalopathy syndrome Posterior reversible encephalopathy syndrome x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

cabozantinib

Side effects:73
Source:FDA Structured Product Label

cabozantinib / cabozantinib

Side effects:131
Source:EMA

Color scheme:

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