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Imatinib

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XE01

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 26 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Neoplasm malignant Neoplasm malignant 79% - 91.2% x x x x
Haemoglobin decreased Haemoglobin decreased 0.5% - 80.3% 0% - 27% x x
Lethargy Lethargy 11.7% - 74.9% x
Oedema peripheral Oedema peripheral 0.3% - 40.9% 0% - 14.8% x x x x x
Edema of lower extremities x x x x x x x x x x x x
Asthenia Fatigue very common, 0% - 74.9% 1.2% - 40.9% x x x x x x x x x x x x x x x x x x x
Asthenia common, 0% - 74.9% x x x x x x x x x x x x x x x x x x x
Fatigue Fatigue very common, 0% - 74.9% 1.2% - 40.9% x x x x x x x x x x x x x x x x x x x
Hypoproteinaemia Hypoproteinaemia 0% - 31.8% x x
Skin exfoliation Skin exfoliation 7.6% - 49.8% x
Neutrophil count decreased Neutrophil count decreased 3.3% - 33.3% 0.9% - 6.1% x x
Abdominal pain Abdominal pain very common, 0% - 57.2% 1.4% - 22.3% x x x x x x x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain very common, 0% - 57.2% 1.4% - 22.3% x x x x x x x x x x x x x x x x x x x
Dermatitis Dermatitis very common, 1.5% - 38.9% x x x x x x x x x x x x x x x x x
Rash very common, 0% - 53% 0% - 12.8% x x x x x x x x x x x x x x x x x x x
Diarrhoea Diarrhoea very common, 0.464% - 70% 1.4% - 29.3% x x x x x x x x x x x x x x x x x x x
Loose stools 0% - 12% x x x x x x
Eczema Eczema very common x x x x x
Rash Rash very common, 0% - 53% 0% - 12.8% x x x x x x x x x x x x x x x x x x x
Headache Headache very common, 0% - 43.3% 0% - 20.3% x x x x x x x x x x x x x x x x x x x
Musculoskeletal pain Musculoskeletal pain very common, 0% - 49% x x x x x x x x x x x x x x x x x x x
Nausea Nausea very common, 0.4% - 74% 1.2% - 27.8% x x x x x x x x x x x x x x x x x x x
Muscle spasms Muscle spasms very common, 0% - 49% 0% - 3.3% x x x x x x
Cramp muscle very common, 0% - 62% x x x x x x x x x x x x x x x x x x x
Vomiting Vomiting very common, 0.5% - 58% 0.6% - 13.9% x x x x x x x x x x x x x x x x x x x
Periorbital oedema Periorbital oedema very common, 0.5% - 74.2% 0% - 14.5% x x x x x x x x x
Bone pain Bone pain very common, 1.6% - 15.6% x x x x x x x
White blood cell count decreased White blood cell count decreased 0.6% - 47% 0.3% - 4.3% x x
Pain Pain 0.7% - 45.5% x x x
Depression Depression uncommon, 0% - 35.8% 0.6% - 6.4% x x x x x x x x x x x x
Hypoalbuminaemia Hypoalbuminaemia 0% - 21.2% x x x
Skin toxicity Skin toxicity 5.7% - 20.1% x
Arthralgia Arthralgia very common, 0% - 40% 0.3% - 14.5% x x x x x x x x x x x x x x x x x x x
Musculoskeletal discomfort Arthralgia very common, 0% - 40% 0.3% - 14.5% x x x x x x x x x x x x x x x x x x x
Myalgia very common, 0% - 38.8% 0.3% - 11.6% x x x x x x x x x x x x x x x x x x x
Dyspepsia Dyspepsia very common, 0% - 27% 0% - 13% x x x x x x x x x x x x x x x x x x x
Heartburn 0.5% - 11.5% x
Digestion impaired x x
Oedema Oedema very common, 0% - 86.1% x x x x x x x x x x x x x x x x x x x
Oedema aggravated x x x x x x x x x x x x x x x
Myalgia Myalgia very common, 0% - 38.8% 0.3% - 11.6% x x x x x x x x x x x x x x x x x x x
Platelet count decreased Platelet count decreased 0% - 14.1% 0% - 3.5% x x
Ascites Ascites uncommon, 3% - 15% x x x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased common, 0% - 42.6% x x x x x x x x x x x x x x x x x x x
Pleural effusion Pleural effusion uncommon, 0% - 15% x x x x x x x x x x
Agranulocytosis Agranulocytosis 3.1% - 16.1% x
Dizziness Lightheadedness 2.8% - 11% x
Dizziness common, 0% - 24.4% 0.3% - 10.7% x x x x x x x x x x x x x x x x x x
Syncope infrequent, uncommon x x x x x x x x x x x x x x
Pharyngitis Pharyngeal mucositis 4.3% - 10% x
Pharyngitis uncommon, 0% - 15% x x x x x x x x x x x x x x
Dyspnoea Dyspnoea common, 0.5% - 21% x x x x x x x x x x x x x x x x x x x
Pneumonia Pneumonia uncommon, 0.155% - 13% x x x x x x x x x x x x x x x x x x x
Fluid retention Fluid retention very common, 0% - 81% x x x x x x x x x x x x x x x x x x x
Generalised oedema common x x x x x x x x x x x x x x x x x x x
Back pain Back pain 0% - 26% 0% - 8.1% x x x x x x x x x x x x x x
Hyperhidrosis Sweating 2.8% - 12.7% x
Sweating increased uncommon, 0.2% - 14.8% x x x x x x x
Abdominal distension Abdominal distension common, 0% - 19.2% 0.3% - 6.4% x x x x x x x x x x x x x x
Alopecia Alopecia common, 0% - 22.3% 0% - 6.7% x x x x x x x x x x x x x x
Decreased appetite Anorexia common, 0% - 35.8% 0% - 8.7% x x x x x x x x x x x x x x x x x x x
Decreased appetite uncommon, 0% - 10.1% x x x x x x
Conjunctivitis Conjunctivitis common, 0% - 7.6% x x x x x x x x x x x x x x
Constipation Constipation common, 0% - 16% 0.3% - 17.7% x x x x x x x x x x x x x x x x x x x
Cough Cough common, 0% - 27% 0% - 11.3% x x x x x x x x x x x x x x x x x x x
Epistaxis Epistaxis common, 0% - 13% x x x x x x x x x x x x x x x
Flatulence Flatulence common, 0% - 34% 0% - 9.6% x x x x x x x x x x x x x x x x x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease common x x x x x x x x x x x x x x
Haemorrhage Haemorrhage postmarketing — 0% - 53% x x x x x x x x x x x x x x x x x x x
Haemoglobin Haemorrhage postmarketing — 0% - 53% x x x x x x x x x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia common x x x x x x
Night sweats Night sweats common, 0.2% - 17% x x x x x x x x x x x x x x x x x x x
Paraesthesia Paraesthesia common, 0% - 12.1% x x x x x x x x x x x x x x
Pruritus Pruritus common, 0% - 25.8% 0% - 7.8% x x x x x x x x x x x x x x x x x x x
Erythema Erythema common x x x x x x
Weight increased Weight increased very common, 0% - 32% 0% - 11.6% x x x x x x x x x x x x x x x x x x x
Dry mouth Dry mouth common, 0% - 10.9% x x x x x x x
Chills Chills common, 3% - 11% x x x x x x
Rigors common, 0% - 34% x x x x x x x x x x x x x x x x x x
Stomatitis Mouth ulceration uncommon, common x x x x x x x x x x x x x x
Stomatitis uncommon, 0.6% - 16.3% 0% - 1.7% x x x x x x
Mouth ulceration Mouth ulceration uncommon, common x x x x x x x x x x x x x x
Generalised oedema Generalised oedema common x x x x x x x x x x x x x x x x x x x
Dry skin Dry skin common, 0% - 6.7% 0% - 5.2% x x x x x x x x x x x x x x
Joint swelling Joint swelling common x x x x x x x x x x x x x x
Lacrimation increased Lacrimation increased common, 0% - 18% 0% - 3.8% x x x x x x x x x x x x x x x x x x
Eyelid oedema Eyelid oedema common x x x x x x
Vision blurred Vision blurred common, 0% - 11.1% 0% - 2.3% x x x x x x x x x x x x x x
Face oedema Face oedema common, 0.3% - 6.8% 0% - 1.2% x x x x x x x x x x x x x x x x x x
Febrile neutropenia Febrile neutropenia common x x x x x x
Insomnia Insomnia common, 0% - 19% 0% - 7.2% x x x x x x x x x x x x x x x x x x
Neutropenia Neutropenia postmarketing — 0% - 100% x x x x x x x x
Anaemia Anaemia postmarketing — 0% - 42% x x x x x x x x x x x x x x x x x x x
Influenza like illness Influenza like illness 0% - 15.9% x
Hypokalaemia Hypokalaemia uncommon, 0.2% - 33.7% 0.6% - 2% x x x x x x x x x x x x x x x x x x x
Oropharyngeal discomfort Throat sore 0% - 11% x x x x
Oropharyngeal pain Throat sore 0% - 11% x x x x
Pain in extremity Pain in extremity 0.3% - 7.4% 0% - 7.2% x
Leukopenia Leukopenia 0.3% - 19.6% 0% - 2.6% x x x x
Abdominal pain upper Abdominal pain upper 0.3% - 6.2% 0% - 6.4% x
Weight decreased Weight decreased infrequent — 0% - 17.3% 0% - 5.2% x x x x x x x x x x x x x x
Dysgeusia Dysgeusia common, 0% - 15% 0% - 2.9% x x x x x x x x x x x x x x x x x
Upper respiratory tract infection Upper respiratory tract infection uncommon — 0% - 21.2% 0% - 3.5% x x x x x x x x x x x x x x x x x x
Hypocalcaemia Hypocalcaemia 0.3% - 5.6% 0% - 1.7% x x
Hypoxia Hypoxia 0.309% - 8.7% x
Sinusitis Sinusitis uncommon, 0.2% - 11.4% x x x x x x x x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased 0% - 37.9% x x x x x x x x x x x x x x x
Mucosal inflammation Mucosal inflammation 0% - 10.3% x
Alanine aminotransferase increased Alanine aminotransferase increased 0% - 34.3% x x x x x x x x x x x x x x x
Photosensitivity reaction Photosensitivity reaction infrequent — 0% - 7.1% x x x x x x x x x x x x x x
Chest pain Chest pain uncommon, 0.4% - 11% x x x x x x x x x x x x x x
Infection Infection postmarketing — 0% - 53.3% x x x x x x x x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage uncommon, 0.2% - 8% x x x x x x x x x x x x x x x
Petechiae Petechiae uncommon, 0% - 10% x x x x x x x x x x x
Tumour haemorrhage Tumour haemorrhage postmarketing — 1% - 4% x x x x x x x x x x x x x x x x x
Ecchymosis Ecchymosis uncommon, 0% - 11% x x x x x x x x x x
Anxiety Anxiety infrequent — 0% - 12% x x x x x x x x x x x x x x
Nasopharyngitis Nasopharyngitis uncommon, 0% - 30.5% x x x x x x x x x x x x x x x x x x
Influenza Influenza uncommon, 0% - 13.8% x x x x x x x x x x x x x x x x x x
Blepharitis Blepharitis uncommon x x x x x x
Cellulitis Cellulitis uncommon x x x x x x
Cheilitis Cheilitis uncommon x x x x x x
Conjunctival haemorrhage Conjunctival haemorrhage infrequent, common x x x x x x x x x x x x x x
Contusion Contusion uncommon x x x x x x x x x x
Libido decreased Libido decreased uncommon x x x x x x
Disturbance in sexual arousal Libido decreased uncommon x x x x x x
Dysphagia Dysphagia uncommon x x x x x x
Dehydration Dehydration infrequent, uncommon x x x x x x x x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative infrequent, uncommon x x x x x x x x x x x x x x
Eosinophilia Eosinophilia postmarketing, uncommon x x x x x x
Eructation Eructation uncommon x x x x x
Oesophagitis Oesophagitis uncommon x x x x x x
Flushing Flushing infrequent, common x x x x x x x x x x x x x x
Folliculitis Folliculitis uncommon x x x x x x
Gastritis Gastritis infrequent, common x x x x x x x x x x x x x x
Gastroenteritis Gastroenteritis infrequent, uncommon x x x x x x x x x x x x x x
Gout Gout infrequent, uncommon x x x x x x x x x x x x x x
Gynaecomastia Gynaecomastia uncommon x x x x x x
Cardiac failure Cardiac failure infrequent x x x x x x x x
Cardiac failure congestive Cardiac failure congestive uncommon x x x x x
Haematemesis Haematemesis uncommon x x x x x x
Haematoma Haematoma uncommon x x x x x x
Subdural haematoma Subdural haematoma uncommon x x x x x x
Haematuria Haematuria infrequent, uncommon x x x x x x x x x x x x x x
Hepatitis Hepatitis uncommon x x x x x x x x x x
Herpes simplex Herpes simplex infrequent, uncommon x x x x x x x x x x x x x x
Herpes zoster Herpes zoster infrequent, uncommon x x x x x x x x x x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia uncommon x x x x x
Hypercalcaemia Hypercalcaemia uncommon x x x x x x
Hyperglycaemia Hyperglycaemia uncommon, 0.6% - 9.8% 1.7% - 11.3% x x x x x x x
Hypertension Hypertension infrequent, uncommon x x x x x x x x x x x x x x
Hypotension Hypotension infrequent — 0.927% - 10.9% x x x x x x x x x x x x x x
Hypotrichosis Hypotrichosis uncommon x x x x x x
Jaundice Jaundice uncommon x x x x x x x
Renal failure acute Renal failure acute uncommon x x x x x x
Acute respiratory failure postmarketing, uncommon x x x x x x
Lymphopenia Lymphopenia uncommon, 0.7% - 10.1% x x x x x x x x x
Melaena Melaena uncommon x x x x x x
Menorrhagia Menorrhagia infrequent, uncommon x x x x x x x x x x x x x x
Nail disorder Nail disorder infrequent x x x x x x x x x
Palpitations Palpitations uncommon, 0% - 5.2% x x x x x x
Pancreatitis Pancreatitis rare, uncommon x x x x x x x x x x x x x
Pancytopenia Pancytopenia infrequent, common x x x x x x x x x x x x x x
Bone marrow depression uncommon x x x x x x
Cytopenia postmarketing x x x x x x x x x x x x x x x x x x
Myelosuppression x x x x x
Neuropathy peripheral Neuropathy peripheral infrequent — 0% - 5.9% 0% - 6.4% x x x x x x x x x x x x x x
Psoriasis Psoriasis infrequent, uncommon x x x x x x x x x x x x
Pulmonary oedema Pulmonary oedema uncommon x x x x x x x x x x x x x x x x x x x
Purpura Purpura infrequent, uncommon x x x x x x x x x x x x x x
Vascular purpura Purpura infrequent, uncommon x x x x x x x x x x x x x x
Renal failure Renal failure infrequent, uncommon x x x x
Restless legs syndrome Restless legs syndrome uncommon x x x x x x
Sciatica Sciatica infrequent, uncommon x x x x x x x x x x x x x x
Pigmentation disorder Pigmentation skin infrequent x x x x x x x x
Gastric ulcer Gastric ulcer infrequent, uncommon x x x x x x x x x x x x x x
Shock Syncope infrequent, uncommon x x x x x x x x x x x x x x
Syncope Syncope infrequent, uncommon x x x x x x x x x x x x x x
Loss of consciousness Syncope infrequent, uncommon x x x x x x x x x x x x x x
Tachycardia Tachycardia infrequent, uncommon x x x x x x x x x x x x x x
Tinnitus Tinnitus infrequent, uncommon x x x x x x x x x x x x x x
Tremor Tremor uncommon x x x x x x
Pollakiuria Pollakiuria infrequent, uncommon x x x x x x x x x x x x x x
Urinary tract infection Urinary tract infection uncommon x x x x x x
Urticaria Urticaria uncommon x x x x x x
Vertigo Vertigo infrequent, uncommon x x x x x x x x x x x x x x
Rash pustular Rash pustular uncommon x x x x x x
Hypophosphataemia Hypophosphataemia infrequent, uncommon x x x x x x x x x x x x x x
Migraine Migraine infrequent, uncommon x x x x x x x x x x x x x x
Blood creatine phosphokinase increased Creatine phosphokinase increased infrequent x x x x x x x x x
Blood creatine phosphokinase increased uncommon x x x x x
Scrotal oedema Scrotal oedema uncommon x x x x x x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased infrequent x x x x x x x x x
Blood lactate dehydrogenase increased uncommon, 0% - 60.1% x x x x x x
Eye pain Eye pain uncommon x x x x x x
Menstruation irregular Menstruation irregular uncommon x x x x x x
Skin hyperpigmentation Skin hyperpigmentation uncommon x x x x x x
Leukoderma Leukoderma uncommon x x x x x x
Musculoskeletal stiffness Muscle stiffness infrequent, uncommon x x x x x x x x x x x x x x
Malaise Malaise uncommon, 11.7% - 74.9% x x x x x x
Discomfort Malaise uncommon, 11.7% - 74.9% x x x x x x
Feeling abnormal Malaise uncommon, 11.7% - 74.9% x x x x x x
Confusional state rare x x x x x x x x x x x x x
Ill-defined disorder Malaise uncommon, 11.7% - 74.9% x x x x x x
Increased appetite Increased appetite uncommon x x x x x x
Memory impairment Memory impairment infrequent, uncommon x x x x x x x x x x x x x x
Eye irritation Eye irritation uncommon x x x x x x
Blood creatinine increased Blood creatinine increased uncommon — 0% - 44.4% 0.3% - 5.8% x x x x x x
Creatinine increased 0% - 8% x x x x x x x x x x x x x x
Dermatitis bullous Bullous eruption infrequent, uncommon x x x x x x x x x x x x x x
Hyperaesthesia Nipple pain uncommon x x x x x x
Nipple pain Nipple pain uncommon x x x x x x
Erectile dysfunction Erectile dysfunction uncommon x x x x x x
Sepsis Sepsis infrequent, uncommon x x x x x x x x x x x x x x
Peripheral coldness Peripheral coldness infrequent, uncommon x x x x x x x x x x x x x x
Dry eye Dry eye infrequent, common x x x x x x x x x x x x x x
Increased tendency to bruise Increased tendency to bruise uncommon x x x x x x
Orbital oedema Orbital oedema uncommon x x x x x x
Lymphadenopathy Lymphadenopathy uncommon x x x x x x
Onychoclasis Onychoclasis uncommon x x x x x x
Sexual dysfunction Sexual dysfunction infrequent, uncommon x x x x x x x x x x x x x x
Renal pain Renal pain uncommon x x x x x x
Blood uric acid increased Hyperuricaemia uncommon x x x x x x
Hyperuricaemia Hyperuricaemia uncommon x x x x x x
Scleral haemorrhage Scleral haemorrhage uncommon x x x x x x
Thrombocytosis Thrombocytosis uncommon x x x x x x
Blood alkaline phosphatase increased Blood alkaline phosphatase increased uncommon, 0% - 16.7% 0% - 7.5% x x x x x x
Phosphatase alkaline increased 0% - 5.5% x x x x x x x x x x x x x x
Laryngeal pain Pharyngolaryngeal pain uncommon, 0% - 18.1% x x x x x x x x x x x x x x x x x
Deafness Hearing impaired uncommon x x x x x x
Hearing impaired Hearing impaired uncommon x x x x x x
Breast enlargement Breast enlargement infrequent, uncommon x x x x x x x x x x x x x x
Somnolence Somnolence infrequent, uncommon x x x x x x x x x x x x x x
Cerebral haemorrhage Cerebral haemorrhage uncommon, 0% - 1% x x x x x x x x x x x x x x x x x
Thrombocytopenia Thrombocytopenia postmarketing — 0% - 97.8% x x x x x x x x x x x x x x x x x x x
Blood bilirubin increased Blood bilirubin increased 0% - 13.1% x x x x x x x x x x x x x x x
Skin disorder Skin disorder 0% - 4.35% x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x
Retinal haemorrhage Retinal haemorrhage rare, uncommon x x x x x x x x x x x x x x
Macular oedema Macular oedema rare, uncommon x x x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock very rare — rare x x x x x x x
Aplastic anaemia Aplastic anaemia rare x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia rare x x x x x x
Angina pectoris Angina pectoris rare x x x x x x
Angioedema Angioedema rare x x x x x x x x x x x x x
Arrhythmia Arrhythmia rare x x x x x x
Arthritis Arthritis rare x x x x x x
Atrial fibrillation Atrial fibrillation rare x x x x x x
Blast cell crisis Blast cell crisis postmarketing x x x
Brain oedema Edema cerebral postmarketing, rare x x x x x x x x x x x x x x x x
Cardiac tamponade Cardiac tamponade postmarketing, rare x x x x x x
Pleuritic pain Pleuritic pain rare x x x x x x
Colitis Colitis rare x x x x x x x x x x x x x x
Confusional state Confusional state rare x x x x x x x x x x x x x
Connective tissue disorder Connective tissue disorder postmarketing x x x x x x
Cyst Cyst postmarketing x x x x x
Drug eruption Drug eruption postmarketing x x
Diverticulitis Diverticulitis postmarketing, rare x x x x x x x x x x
Embolism Embolism postmarketing — uncommon x x x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis very rare, postmarketing x x x x x x
Erythema multiforme Erythema multiforme rare x x x x x x
Stevens-Johnson syndrome rare x x x x x x x x x x x x x x
Eye disorder Eye disorder postmarketing x x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x x x x x
Digestion impaired x x
Glaucoma Glaucoma rare x x x x x x x x x x x x x
Cardiac arrest Cardiac arrest rare x x x x x x
Cardiac disorder Cardiac disorder postmarketing, rare x x x x x x
Hyperkalaemia Hyperkalaemia rare x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity rare x x x x x x x x x
Pulmonary hypertension Pulmonary hypertension rare x x x x x x
Hyponatraemia Hyponatraemia rare, uncommon x x x x x x x x x x x x x x
Immune system disorder Immune system disorder postmarketing x x x
Inflammatory bowel disease Inflammatory bowel disease rare x x x x x x
Intestinal obstruction Intestinal obstruction postmarketing — uncommon x x x x x x x x x x x x x
Chronic myeloid leukaemia Chronic phase chronic myeloid leukemia postmarketing x x x
Lichen planus Lichen planus postmarketing, rare x x x x x x
Mediastinal disorder Mediastinal disorder postmarketing x x x x x x
Myopathy Myopathy postmarketing, rare x x x x x x
Fungal infection Fungal infection rare x x x x x x
Myocardial infarction Myocardial infarction rare x x x x x x
Acute coronary syndrome Myocardial infarction rare x x x x x x
Necrosis Necrosis postmarketing x x x
Necrosis ischaemic Necrosis ischaemic postmarketing, rare x x x x x x x x x x
Osteonecrosis Necrosis ischaemic postmarketing, rare x x x x x x x x x x
Osteonecrosis postmarketing, rare x x x x x x x
Neoplasm Neoplasm postmarketing, 5% - 20.8% x x x x x x x
Nervous system disorder Nervous system disorder postmarketing x x x x x x
Optic neuritis Optic neuritis rare x x x x x x
Papilloedema postmarketing, rare x x x x x x x x x x x x x x x x
Papilloedema Papilloedema postmarketing, rare x x x x x x x x x x x x x x x x
Pericardial effusion Pericardial effusion rare