Side effect information for Imatinib

Side effects

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MedDRA Preferred Term	Side effect	Data for drug	Placebo	Labels
				1	2	3	4	5	6	7	8	9	10	11	12	13	14	15	16	17	18	19	20
Neoplasm malignant	Neoplasm malignant	79% - 91.2%																	x		x
Haemoglobin decreased	Haemoglobin decreased	0.5% - 80.3%	0% - 27%																			x	x
Lethargy	Lethargy	11.7% - 74.9%																					x
Oedema peripheral	Oedema peripheral	0.3% - 40.9%	0% - 14.8%														x	x	x			x	x
Oedema peripheral	Edema of lower extremities					x	x	x	x	x	x	x	x	x	x	x	x	x					x
Asthenia	Fatigue	very common, 0% - 74.9%	1.2% - 40.9%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Asthenia	Asthenia	common, 0% - 74.9%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Fatigue	Fatigue	very common, 0% - 74.9%	1.2% - 40.9%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypoproteinaemia	Hypoproteinaemia	0% - 31.8%																				x	x
Skin exfoliation	Skin exfoliation	7.6% - 49.8%																					x
Neutrophil count decreased	Neutrophil count decreased	3.3% - 33.3%	0.9% - 6.1%																			x	x
Abdominal pain	Abdominal pain	very common, 0% - 57.2%	1.4% - 22.3%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrointestinal pain	Abdominal pain	very common, 0% - 57.2%	1.4% - 22.3%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dermatitis	Dermatitis	very common, 1.5% - 38.9%				x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x	x
Dermatitis	Rash	very common, 0% - 53%	0% - 12.8%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Diarrhoea	Diarrhoea	very common, 0.464% - 70%	1.4% - 29.3%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Diarrhoea	Loose stools	0% - 12%												x	x	x	x	x	x			x
Eczema	Eczema	very common																		x	x	x
Rash	Rash	very common, 0% - 53%	0% - 12.8%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Headache	Headache	very common, 0% - 43.3%	0% - 20.3%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Musculoskeletal pain	Musculoskeletal pain	very common, 0% - 49%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Nausea	Nausea	very common, 0.4% - 74%	1.2% - 27.8%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Muscle spasms	Muscle spasms	very common, 0% - 49%	0% - 3.3%																	x	x	x	x
Muscle spasms	Cramp muscle	very common, 0% - 62%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Vomiting	Vomiting	very common, 0.5% - 58%	0.6% - 13.9%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Periorbital oedema	Periorbital oedema	very common, 0.5% - 74.2%	0% - 14.5%														x	x	x	x	x	x	x
Bone pain	Bone pain	very common, 1.6% - 15.6%																	x	x	x	x	x
White blood cell count decreased	White blood cell count decreased	0.6% - 47%	0.3% - 4.3%																			x	x
Pain	Pain	0.7% - 45.5%																	x			x	x
Depression	Depression	uncommon, 0% - 35.8%	0.6% - 6.4%										x	x	x	x	x	x	x	x	x	x	x
Hypoalbuminaemia	Hypoalbuminaemia	0% - 21.2%																	x			x	x
Skin toxicity	Skin toxicity	5.7% - 20.1%																					x
Arthralgia	Arthralgia	very common, 0% - 40%	0.3% - 14.5%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Musculoskeletal discomfort	Arthralgia	very common, 0% - 40%	0.3% - 14.5%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Musculoskeletal discomfort	Myalgia	very common, 0% - 38.8%	0.3% - 11.6%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dyspepsia	Dyspepsia	very common, 0% - 27%	0% - 13%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
	Heartburn	0.5% - 11.5%																					x
	Digestion impaired																					x	x
Oedema	Oedema	very common, 0% - 86.1%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Oedema	Oedema aggravated				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			x	x
Myalgia	Myalgia	very common, 0% - 38.8%	0.3% - 11.6%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Platelet count decreased	Platelet count decreased	0% - 14.1%	0% - 3.5%																			x	x
Ascites	Ascites	uncommon, 3% - 15%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Body temperature increased	Body temperature increased	common, 0% - 42.6%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Pleural effusion	Pleural effusion	uncommon, 0% - 15%												x	x	x	x	x		x	x	x	x
Agranulocytosis	Agranulocytosis	3.1% - 16.1%																					x
Dizziness	Lightheadedness	2.8% - 11%																					x
	Dizziness	common, 0% - 24.4%	0.3% - 10.7%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
	Syncope	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Pharyngitis	Pharyngeal mucositis	4.3% - 10%																					x
Pharyngitis	Pharyngitis	uncommon, 0% - 15%									x	x	x	x	x	x	x	x	x	x	x	x	x
Dyspnoea	Dyspnoea	common, 0.5% - 21%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Pneumonia	Pneumonia	uncommon, 0.155% - 13%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Fluid retention	Fluid retention	very common, 0% - 81%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Fluid retention	Generalised oedema	common			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Back pain	Back pain	0% - 26%	0% - 8.1%			x	x	x	x	x	x	x	x	x	x	x	x	x	x			x	x
Hyperhidrosis	Sweating	2.8% - 12.7%																					x
Hyperhidrosis	Sweating increased	uncommon, 0.2% - 14.8%																	x	x	x	x	x
Abdominal distension	Abdominal distension	common, 0% - 19.2%	0.3% - 6.4%								x	x	x	x	x	x	x	x	x	x	x	x	x
Alopecia	Alopecia	common, 0% - 22.3%	0% - 6.7%								x	x	x	x	x	x	x	x	x	x	x	x	x
Decreased appetite	Anorexia	common, 0% - 35.8%	0% - 8.7%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Decreased appetite	Decreased appetite	uncommon, 0% - 10.1%																		x	x	x	x
Conjunctivitis	Conjunctivitis	common, 0% - 7.6%									x	x	x	x	x	x	x	x	x	x	x	x	x
Constipation	Constipation	common, 0% - 16%	0.3% - 17.7%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Cough	Cough	common, 0% - 27%	0% - 11.3%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Epistaxis	Epistaxis	common, 0% - 13%			x	x	x	x	x	x				x	x	x	x	x		x	x	x	x
Flatulence	Flatulence	common, 0% - 34%	0% - 9.6%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Gastrooesophageal reflux disease	Gastrooesophageal reflux disease	common									x	x	x	x	x	x	x	x	x	x	x	x	x
Haemorrhage	Haemorrhage	postmarketing — 0% - 53%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Haemoglobin	Haemorrhage	postmarketing — 0% - 53%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypoaesthesia	Hypoaesthesia	common																		x	x	x	x
Night sweats	Night sweats	common, 0.2% - 17%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Paraesthesia	Paraesthesia	common, 0% - 12.1%									x	x	x	x	x	x	x	x	x	x	x	x	x
Pruritus	Pruritus	common, 0% - 25.8%	0% - 7.8%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Erythema	Erythema	common																		x	x	x	x
Weight increased	Weight increased	very common, 0% - 32%	0% - 11.6%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dry mouth	Dry mouth	common, 0% - 10.9%																	x	x	x	x	x
Chills	Chills	common, 3% - 11%																		x	x	x	x
Chills	Rigors	common, 0% - 34%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Stomatitis	Mouth ulceration	uncommon, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Stomatitis	Stomatitis	uncommon, 0.6% - 16.3%	0% - 1.7%																	x	x	x	x
Mouth ulceration	Mouth ulceration	uncommon, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Generalised oedema	Generalised oedema	common			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Dry skin	Dry skin	common, 0% - 6.7%	0% - 5.2%								x	x	x	x	x	x	x	x	x	x	x	x	x
Joint swelling	Joint swelling	common									x	x	x	x	x	x	x	x	x	x	x	x	x
Lacrimation increased	Lacrimation increased	common, 0% - 18%	0% - 3.8%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Eyelid oedema	Eyelid oedema	common																		x	x	x	x
Vision blurred	Vision blurred	common, 0% - 11.1%	0% - 2.3%								x	x	x	x	x	x	x	x	x	x	x	x	x
Face oedema	Face oedema	common, 0.3% - 6.8%	0% - 1.2%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Febrile neutropenia	Febrile neutropenia	common																		x	x	x	x
Insomnia	Insomnia	common, 0% - 19%	0% - 7.2%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Neutropenia	Neutropenia	postmarketing — 0% - 100%			x				x	x									x	x	x		x
Anaemia	Anaemia	postmarketing — 0% - 42%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Influenza like illness	Influenza like illness	0% - 15.9%																	x
Hypokalaemia	Hypokalaemia	uncommon, 0.2% - 33.7%	0.6% - 2%		x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Oropharyngeal discomfort	Throat sore	0% - 11%				x	x	x	x	x
Oropharyngeal pain	Throat sore	0% - 11%				x	x	x	x	x
Pain in extremity	Pain in extremity	0.3% - 7.4%	0% - 7.2%																				x
Leukopenia	Leukopenia	0.3% - 19.6%	0% - 2.6%														x	x	x				x
Abdominal pain upper	Abdominal pain upper	0.3% - 6.2%	0% - 6.4%																				x
Weight decreased	Weight decreased	infrequent — 0% - 17.3%	0% - 5.2%								x	x	x	x	x	x	x	x	x	x	x	x	x
Dysgeusia	Dysgeusia	common, 0% - 15%	0% - 2.9%			x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x	x
Upper respiratory tract infection	Upper respiratory tract infection	uncommon — 0% - 21.2%	0% - 3.5%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Hypocalcaemia	Hypocalcaemia	0.3% - 5.6%	0% - 1.7%																x				x
Hypoxia	Hypoxia	0.309% - 8.7%																					x
Sinusitis	Sinusitis	uncommon, 0.2% - 11.4%									x	x	x	x	x	x	x	x	x	x	x	x	x
Aspartate aminotransferase increased	Aspartate aminotransferase increased	0% - 37.9%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			x	x
Mucosal inflammation	Mucosal inflammation	0% - 10.3%																	x
Alanine aminotransferase increased	Alanine aminotransferase increased	0% - 34.3%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			x	x
Photosensitivity reaction	Photosensitivity reaction	infrequent — 0% - 7.1%									x	x	x	x	x	x	x	x	x	x	x	x	x
Chest pain	Chest pain	uncommon, 0.4% - 11%									x	x	x	x	x	x	x	x	x	x	x	x	x
Infection	Infection	postmarketing — 0% - 53.3%							x	x	x	x	x			x	x	x			x	x	x
Gastrointestinal haemorrhage	Gastrointestinal haemorrhage	uncommon, 0.2% - 8%			x	x					x	x	x	x	x	x	x	x		x	x	x	x
Petechiae	Petechiae	uncommon, 0% - 10%			x	x	x	x	x	x										x	x	x	x
Tumour haemorrhage	Tumour haemorrhage	postmarketing — 1% - 4%				x	x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x
Ecchymosis	Ecchymosis	uncommon, 0% - 11%				x	x	x	x	x										x	x	x	x
Anxiety	Anxiety	infrequent — 0% - 12%									x	x	x	x	x	x	x	x	x	x	x	x	x
Nasopharyngitis	Nasopharyngitis	uncommon, 0% - 30.5%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Influenza	Influenza	uncommon, 0% - 13.8%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blepharitis	Blepharitis	uncommon																		x	x	x	x
Cellulitis	Cellulitis	uncommon																		x	x	x	x
Cheilitis	Cheilitis	uncommon																		x	x	x	x
Conjunctival haemorrhage	Conjunctival haemorrhage	infrequent, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Contusion	Contusion	uncommon												x	x	x	x	x		x	x	x	x
Libido decreased	Libido decreased	uncommon																		x	x	x	x
Disturbance in sexual arousal	Libido decreased	uncommon																		x	x	x	x
Dysphagia	Dysphagia	uncommon																		x	x	x	x
Dehydration	Dehydration	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Dermatitis exfoliative	Dermatitis exfoliative	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Eosinophilia	Eosinophilia	postmarketing, uncommon																		x	x	x	x
Eructation	Eructation	uncommon																		x	x		x
Oesophagitis	Oesophagitis	uncommon																		x	x	x	x
Flushing	Flushing	infrequent, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Folliculitis	Folliculitis	uncommon																		x	x	x	x
Gastritis	Gastritis	infrequent, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Gastroenteritis	Gastroenteritis	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Gout	Gout	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Gynaecomastia	Gynaecomastia	uncommon																		x	x	x	x
Cardiac failure	Cardiac failure	infrequent									x	x	x	x	x	x	x	x	x
Cardiac failure congestive	Cardiac failure congestive	uncommon																		x	x	x
Haematemesis	Haematemesis	uncommon																		x	x	x	x
Haematoma	Haematoma	uncommon																		x	x	x	x
Subdural haematoma	Subdural haematoma	uncommon																	x	x		x	x
Haematuria	Haematuria	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Hepatitis	Hepatitis	uncommon													x	x	x	x	x	x	x	x	x
Herpes simplex	Herpes simplex	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Herpes zoster	Herpes zoster	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Hyperbilirubinaemia	Hyperbilirubinaemia	uncommon																	x	x	x
Hypercalcaemia	Hypercalcaemia	uncommon																		x	x	x	x
Hyperglycaemia	Hyperglycaemia	uncommon, 0.6% - 9.8%	1.7% - 11.3%																x	x	x	x	x
Hypertension	Hypertension	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Hypotension	Hypotension	infrequent — 0.927% - 10.9%									x	x	x	x	x	x	x	x	x	x	x	x	x
Hypotrichosis	Hypotrichosis	uncommon																		x	x	x	x
Jaundice	Jaundice	uncommon																	x	x	x	x	x
Renal failure acute	Renal failure acute	uncommon																		x	x	x	x
Renal failure acute	Acute respiratory failure	postmarketing, uncommon																	x	x	x	x
Lymphopenia	Lymphopenia	uncommon, 0.7% - 10.1%															x	x	x	x	x	x	x
Melaena	Melaena	uncommon																		x	x	x	x
Menorrhagia	Menorrhagia	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Nail disorder	Nail disorder	infrequent									x	x	x	x	x	x	x	x	x				x
Palpitations	Palpitations	uncommon, 0% - 5.2%																		x	x	x	x
Pancreatitis	Pancreatitis	rare, uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Pancytopenia	Pancytopenia	infrequent, common									x	x	x	x	x	x	x	x	x	x	x	x	x
	Bone marrow depression	uncommon																		x	x	x	x
	Cytopenia	postmarketing			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x
	Myelosuppression																			x	x		x
Neuropathy peripheral	Neuropathy peripheral	infrequent — 0% - 5.9%	0% - 6.4%								x	x	x	x	x	x	x	x	x	x	x	x	x
Psoriasis	Psoriasis	infrequent, uncommon										x	x	x	x	x	x	x		x	x	x	x
Pulmonary oedema	Pulmonary oedema	uncommon			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Purpura	Purpura	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Vascular purpura	Purpura	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Renal failure	Renal failure	infrequent, uncommon									x	x	x									x
Restless legs syndrome	Restless legs syndrome	uncommon																		x	x	x	x
Sciatica	Sciatica	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Pigmentation disorder	Pigmentation skin	infrequent									x	x	x	x	x	x	x	x	x
Gastric ulcer	Gastric ulcer	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Shock	Syncope	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Syncope	Syncope	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Loss of consciousness	Syncope	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Tachycardia	Tachycardia	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Tinnitus	Tinnitus	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Tremor	Tremor	uncommon																		x	x	x	x
Pollakiuria	Pollakiuria	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Urinary tract infection	Urinary tract infection	uncommon																		x	x	x	x
Urticaria	Urticaria	uncommon																		x	x	x	x
Vertigo	Vertigo	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Rash pustular	Rash pustular	uncommon																		x	x	x	x
Hypophosphataemia	Hypophosphataemia	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Migraine	Migraine	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Blood creatine phosphokinase increased	Creatine phosphokinase increased	infrequent									x	x	x	x	x	x	x	x	x				x
Blood creatine phosphokinase increased	Blood creatine phosphokinase increased	uncommon																		x	x	x
Scrotal oedema	Scrotal oedema	uncommon																		x	x	x	x
Blood lactate dehydrogenase increased	Lactic dehydrogenase activity increased	infrequent									x	x	x	x	x	x	x	x	x				x
Blood lactate dehydrogenase increased	Blood lactate dehydrogenase increased	uncommon, 0% - 60.1%																		x	x	x	x
Eye pain	Eye pain	uncommon																		x	x	x	x
Menstruation irregular	Menstruation irregular	uncommon																		x	x	x	x
Skin hyperpigmentation	Skin hyperpigmentation	uncommon																		x	x	x	x
Leukoderma	Leukoderma	uncommon																		x	x	x	x
Musculoskeletal stiffness	Muscle stiffness	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Malaise	Malaise	uncommon, 11.7% - 74.9%																		x	x	x	x
Discomfort	Malaise	uncommon, 11.7% - 74.9%																		x	x	x	x
Feeling abnormal	Malaise	uncommon, 11.7% - 74.9%																		x	x	x	x
Feeling abnormal	Confusional state	rare										x	x	x	x	x	x	x	x	x	x	x	x
Ill-defined disorder	Malaise	uncommon, 11.7% - 74.9%																		x	x	x	x
Increased appetite	Increased appetite	uncommon																		x	x	x	x
Memory impairment	Memory impairment	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Eye irritation	Eye irritation	uncommon																		x	x	x	x
Blood creatinine increased	Blood creatinine increased	uncommon — 0% - 44.4%	0.3% - 5.8%																	x	x	x	x
Blood creatinine increased	Creatinine increased	0% - 8%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x				x
Dermatitis bullous	Bullous eruption	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Hyperaesthesia	Nipple pain	uncommon																		x	x	x	x
Nipple pain	Nipple pain	uncommon																		x	x	x	x
Erectile dysfunction	Erectile dysfunction	uncommon																		x	x	x	x
Sepsis	Sepsis	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Peripheral coldness	Peripheral coldness	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Dry eye	Dry eye	infrequent, common									x	x	x	x	x	x	x	x	x	x	x	x	x
Increased tendency to bruise	Increased tendency to bruise	uncommon																		x	x	x	x
Orbital oedema	Orbital oedema	uncommon																		x	x	x	x
Lymphadenopathy	Lymphadenopathy	uncommon																		x	x	x	x
Onychoclasis	Onychoclasis	uncommon																		x	x	x	x
Sexual dysfunction	Sexual dysfunction	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Renal pain	Renal pain	uncommon																		x	x	x	x
Blood uric acid increased	Hyperuricaemia	uncommon																		x	x	x	x
Hyperuricaemia	Hyperuricaemia	uncommon																		x	x	x	x
Scleral haemorrhage	Scleral haemorrhage	uncommon																		x	x	x	x
Thrombocytosis	Thrombocytosis	uncommon																		x	x	x	x
Blood alkaline phosphatase increased	Blood alkaline phosphatase increased	uncommon, 0% - 16.7%	0% - 7.5%																	x	x	x	x
Blood alkaline phosphatase increased	Phosphatase alkaline increased	0% - 5.5%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x				x
Laryngeal pain	Pharyngolaryngeal pain	uncommon, 0% - 18.1%					x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Deafness	Hearing impaired	uncommon																		x	x	x	x
Hearing impaired	Hearing impaired	uncommon																		x	x	x	x
Breast enlargement	Breast enlargement	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Somnolence	Somnolence	infrequent, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Cerebral haemorrhage	Cerebral haemorrhage	uncommon, 0% - 1%				x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Thrombocytopenia	Thrombocytopenia	postmarketing — 0% - 97.8%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Blood bilirubin increased	Blood bilirubin increased	0% - 13.1%			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x			x	x
Skin disorder	Skin disorder	0% - 4.35%																					x
Skin disorder	Unspecified disorder of skin and subcutaneous tissue	postmarketing																		x	x	x	x
Retinal haemorrhage	Retinal haemorrhage	rare, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Macular oedema	Macular oedema	rare, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Anaphylactic shock	Anaphylactic shock	very rare — rare																	x	x	x	x	x
Aplastic anaemia	Aplastic anaemia	rare									x	x	x	x	x	x	x	x	x				x
Haemolytic anaemia	Haemolytic anaemia	rare																		x	x	x	x
Angina pectoris	Angina pectoris	rare																		x	x	x	x
Angioedema	Angioedema	rare									x	x	x	x	x	x	x	x		x	x	x	x
Arrhythmia	Arrhythmia	rare																		x	x	x	x
Arthritis	Arthritis	rare																		x	x	x	x
Atrial fibrillation	Atrial fibrillation	rare																		x	x	x	x
Blast cell crisis	Blast cell crisis	postmarketing																			x
Brain oedema	Edema cerebral	postmarketing, rare					x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Cardiac tamponade	Cardiac tamponade	postmarketing, rare																	x	x	x	x
Pleuritic pain	Pleuritic pain	rare																		x	x	x	x
Colitis	Colitis	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Confusional state	Confusional state	rare										x	x	x	x	x	x	x	x	x	x	x	x
Connective tissue disorder	Connective tissue disorder	postmarketing																		x	x	x	x
Cyst	Cyst	postmarketing																		x	x	x
Drug eruption	Drug eruption	postmarketing																					x
Diverticulitis	Diverticulitis	postmarketing, rare													x	x	x	x	x	x	x	x	x
Embolism	Embolism	postmarketing — uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Toxic epidermal necrolysis	Toxic epidermal necrolysis	very rare, postmarketing																		x	x	x	x
Erythema multiforme	Erythema multiforme	rare																		x	x	x	x
Erythema multiforme	Stevens-Johnson syndrome	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Eye disorder	Eye disorder	postmarketing																		x	x	x	x
Gastrointestinal disorder	Gastrointestinal disorder	postmarketing																		x	x	x	x
Gastrointestinal disorder	Digestion impaired																					x	x
Glaucoma	Glaucoma	rare										x	x	x	x	x	x	x	x	x	x	x	x
Cardiac arrest	Cardiac arrest	rare																		x	x	x	x
Cardiac disorder	Cardiac disorder	postmarketing, rare																		x	x	x	x
Hyperkalaemia	Hyperkalaemia	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Hypersensitivity	Hypersensitivity	rare									x	x	x	x	x	x	x	x	x				x
Pulmonary hypertension	Pulmonary hypertension	rare																		x	x	x	x
Hyponatraemia	Hyponatraemia	rare, uncommon									x	x	x	x	x	x	x	x	x	x	x	x	x
Immune system disorder	Immune system disorder	postmarketing																			x
Inflammatory bowel disease	Inflammatory bowel disease	rare																		x	x	x	x
Intestinal obstruction	Intestinal obstruction	postmarketing — uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Chronic myeloid leukaemia	Chronic phase chronic myeloid leukemia	postmarketing																			x
Lichen planus	Lichen planus	postmarketing, rare																		x	x	x	x
Mediastinal disorder	Mediastinal disorder	postmarketing																		x	x	x	x
Myopathy	Myopathy	postmarketing, rare																		x	x	x	x
Fungal infection	Fungal infection	rare																		x	x	x	x
Myocardial infarction	Myocardial infarction	rare																		x	x	x	x
Acute coronary syndrome	Myocardial infarction	rare																		x	x	x	x
Necrosis	Necrosis	postmarketing																			x
Necrosis ischaemic	Necrosis ischaemic	postmarketing, rare													x	x	x	x	x	x	x	x	x
Osteonecrosis	Necrosis ischaemic	postmarketing, rare													x	x	x	x	x	x	x	x	x
Osteonecrosis	Osteonecrosis	postmarketing, rare													x	x	x	x	x	x		x	x
Neoplasm	Neoplasm	postmarketing, 5% - 20.8%																	x	x	x	x	x
Nervous system disorder	Nervous system disorder	postmarketing																		x	x	x	x
Optic neuritis	Optic neuritis	rare																		x	x	x	x
Optic neuritis	Papilloedema	postmarketing, rare					x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Papilloedema	Papilloedema	postmarketing, rare					x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Pericardial effusion	Pericardial effusion	rare			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Pericarditis	Pericarditis	postmarketing, rare										x	x	x	x	x	x	x	x	x	x	x	x
Polyp	Polyp	postmarketing																		x	x	x
Pulmonary fibrosis	Pulmonary fibrosis	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Rhabdomyolysis	Rhabdomyolysis	postmarketing, rare																		x	x	x	x
Convulsion	Convulsion	rare										x	x	x	x	x	x	x	x	x	x	x	x
Stevens-Johnson syndrome	Stevens-Johnson syndrome	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Thrombosis	Thrombosis	postmarketing — uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Tumour lysis syndrome	Tumour lysis syndrome	rare																		x	x	x
Angiopathy	Angiopathy	postmarketing										x	x	x	x	x	x	x		x	x	x	x
Vitreous haemorrhage	Vitreous haemorrhage	postmarketing, rare										x	x	x	x	x	x	x	x	x	x	x	x
Acute febrile neutrophilic dermatosis	Acute febrile neutrophilic dermatosis	rare													x	x	x	x	x	x	x	x	x
Hepatic failure	Hepatic failure	postmarketing — 4% - 17.3%													x	x	x	x	x	x	x	x	x
Cataract	Cataract	rare																		x	x	x	x
Hepatitis cholestatic	Hepatitis cholestatic	postmarketing																	x		x
Leukocytoclastic vasculitis	Allergic cutaneous angiitis	rare																		x	x	x	x
Gastrointestinal perforation	Gastrointestinal perforation	postmarketing, uncommon													x	x	x	x	x	x	x	x
Growth retardation	Growth retardation	postmarketing																		x	x	x	x
Pulmonary haemorrhage	Pulmonary haemorrhage	rare																		x	x	x	x
Hypomagnesaemia	Hypomagnesaemia	rare																		x	x	x	x
Intracranial pressure increased	Intracranial pressure increased	postmarketing, rare					x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x
Muscular weakness	Muscular weakness	rare																		x	x	x	x
Hepatic necrosis	Hepatic necrosis	rare																	x	x	x	x
Interstitial lung disease	Interstitial pneumonia	rare									x	x	x	x	x	x	x	x	x				x
Interstitial lung disease	Interstitial lung disease	postmarketing, uncommon																		x	x	x	x
Rash vesicular	Rash vesicular	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Nail discolouration	Nail discolouration	rare																		x	x	x	x
Acute respiratory failure	Acute respiratory failure	postmarketing, uncommon																	x	x	x	x
Tumour necrosis	Tumour necrosis	postmarketing — uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Haemorrhagic ovarian cyst	Haemorrhagic ovarian cyst	very rare — rare																		x	x	x	x
Amylase increased	Blood amylase increased	rare																		x	x	x	x
Acute generalised exanthematous pustulosis	Acute generalised exanthematous pustulosis	rare									x	x	x	x	x	x	x	x	x	x	x	x	x
Ileus	Ileus	postmarketing — uncommon										x	x	x	x	x	x	x	x	x	x	x	x
Lichenoid keratosis	Lichenoid keratosis	postmarketing, rare																		x	x	x	x
Mental disorder	Mental disorder																			x	x	x
Bladder cancer	Bladder cancer																		x
Bone disorder	Bone disorder																					x
Breast disorder	Breast disorder																			x	x	x
Hypoglycaemia	Hypoglycaemia																		x
Mastocytosis	Mastocytosis																		x
Musculoskeletal disorder	Musculoskeletal disorder																x	x	x				x
Rhinitis	Rhinitis																x	x	x				x
Ulcer	Ulcer																			x		x
Urethral disorder	Urinary tract disorder																			x	x	x
Urinary tract disorder	Urinary tract disorder																			x	x	x
Vasculitis	Vasculitis
Lower respiratory tract infection	Lower respiratory tract infection																x	x	x				x
Malnutrition	Malnutrition																			x	x	x
Acute hepatic failure	Acute hepatic failure				x	x	x	x	x	x	x	x	x	x	x	x	x	x					x
Dyspnoea exertional	Dyspnoea exertional																x	x	x				x
Hepatotoxicity	Hepatotoxicity			x	x	x	x	x	x	x	x	x	x	x	x	x	x	x		x		x	x
Gastrointestinal obstruction	Gastrointestinal obstruction																			x		x
Gastrointestinal stromal tumour	Gastrointestinal stromal tumour																		x				x
Hepatobiliary disease	Hepatobiliary disease																		x	x	x	x
Chronic eosinophilic leukaemia	Chronic eosinophilic leukaemia																		x				x
Prostate cancer	Prostate cancer																		x
Haematological malignancy	Haematological malignancy																x	x	x				x
Drug interaction	Drug interaction																		x
Skin cancer	Skin carcinoma																		x
Renal cancer	Renal cancer																		x
Eye oedema	Eye oedema																x	x	x				x
Infestation	Infestation NOS																			x	x	x
Post procedural haemorrhage	Post procedural haemorrhage													x	x	x	x	x
Haematochezia	Blood in stool													x	x	x	x	x

Side effects:	45
Source:	FDA

Side effects:	61
Source:	FDA

Side effects:	64
Source:	FDA

Side effects:	64
Source:	FDA

Side effects:	66
Source:	FDA

Search results :

Imatinib

Side effects

Indications

IMATINIB MESYLATE / GLEEVEC

IMATINIB MESYLATE / GLEEVEC

imatinib mesylate / Gleevec

IMATINIB MESYLATE / GLEEVEC

imatinib mesylate / Gleevec

imatinib mesylate / Gleevec

IMATINIB MESYLATE / GLEEVEC

IMATINIB MESYLATE / GLEEVEC

imatinib mesylate / Gleevec

IMATINIB MESYLATE / GLEEVEC

IMATINIB MESYLATE / GLEEVEC

imatinib mesylate / Gleevec

IMATINIB MESYLATE / GLEEVEC

imatinib mesylate / Gleevec

IMATINIB MESYLATE / GLEEVEC

IMATINIB (IMATINIB MESYLATE) / GLEEVEC

imatinib mesilate / Glivec, Film coated tablet

imatinib / imatinib

imatinib as the mesylate salt. (beta crystals) / GLIVEC

IMATINIB

Color scheme:

Indication	Labels
Acute lymphocytic leukaemia	x													x	x	x	x	x	x
Aggressive systemic mastocytosis	x													x	x				x
Blast cell crisis	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x		x
Cardiac failure congestive																x		x
Chronic eosinophilic leukaemia	x													x	x		x	x	x
Chronic myeloid leukaemia	x	x	x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x
Chronic phase chronic myeloid leukemia						x	x	x	x	x	x	x	x	x	x			x
Dermatofibrosarcoma protuberans	x													x	x	x	x	x	x
Gastrointestinal stromal tumour	x		x	x	x	x	x	x	x	x	x	x	x	x	x		x		x
Hypereosinophilic syndrome	x													x	x	x	x	x	x
Infection																x	x
Leukaemia																			x
Neutropenia																x	x
Philadelphia chromosome positive			x	x	x	x	x	x	x	x	x	x	x	x	x		x	x	x
Pleural effusion																x		x
Renal failure																x		x
Systemic mastocytosis																	x

		100%
		75%
		50%
		10%
		frequent (1% to 100%)
		infrequent (0.1% to 1%)
		rare (<0.1%)
		postmarketing
		0%
		no frequency information
		not found on label

Side effects:	181
Source:	Health Canada

Side effects:	280
Source:	FDA Structured Product Label