Octreotide
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
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2
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3
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4
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5
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6
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7
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8
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9
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10
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11
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12
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Diarrhoea
|
Diarrhoea
|
very common, 3.1% - 57.9%
|
10.9% - 14.5%
|
|
|
|
|
|
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x
|
x
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|
|
x
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Loose stools
|
common, 3.1% - 36%
|
14.5%
|
|
x
|
x
|
x
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x
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x
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x
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x
|
x
|
|
x
|
x
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Abdominal discomfort
|
Abdominal discomfort
|
4.1% - 43.9%
|
12.7%
|
|
x
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x
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x
|
x
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|
|
|
|
|
x
|
x
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Nausea
|
Nausea
|
very common, 8.7% - 29.8%
|
10.9%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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Abdominal pain
|
Abdominal pain
|
very common
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|
|
|
|
|
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x
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x
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x
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x
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x
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x
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Abdominal cramps
|
|
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x
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x
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Stomach ache
|
|
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x
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Gastrointestinal pain
|
Abdominal pain
|
very common
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|
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|
|
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x
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x
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x
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x
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x
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x
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Headache
|
Headache
|
very common, 13.3% - 18.4%
|
10.9%
|
|
|
|
|
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x
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x
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x
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x
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|
x
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Hyperglycaemia
|
Hyperglycaemia
|
very common, 15%
|
|
|
x
|
x
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x
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x
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x
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x
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x
|
x
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x
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x
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x
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Pain
|
Pain localised
|
very common
|
|
|
|
|
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x
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x
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x
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x
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Pain
|
0.5% - 8-10%
|
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Stinging
|
|
|
|
|
|
|
|
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x
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x
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x
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x
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x
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x
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Flatulence
|
Flatulence
|
very common, 0.5% - 13.2%
|
3.64%
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Abdominal bloating
|
common
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|
|
|
|
|
|
x
|
x
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x
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x
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x
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x
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Injection site pain
|
Injection site pain
|
8.2% - 9.6%
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|
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x
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x
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Constipation
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Constipation
|
very common, 1% - 8.8%
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|
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Dizziness
|
Dizziness
|
common, 8.33% - 14.9%
|
10.9%
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Syncope
|
|
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x
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x
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x
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x
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x
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Abdominal distension
|
Abdominal distension
|
3.33% - 7.9%
|
|
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Abdominal bloating
|
common
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x
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x
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x
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x
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x
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x
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Distention
|
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x
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Asthenia
|
Fatigue
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5% - 9.65%
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3.64%
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x
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Asthenia
|
1-0%
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Fatigue
|
Fatigue
|
5% - 9.65%
|
3.64%
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x
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Tired and heavy
|
2.6%
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x
|
x
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Haematoma
|
Haematoma
|
1.67% - 9.65%
|
10.9%
|
|
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x
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x
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x
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Abnormal faeces
|
Abnormal faeces
|
0.5% - 6.14%
|
|
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x
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x
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x
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x
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x
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x
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Decreased appetite
|
Anorexia
|
common, 0-2%
|
|
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x
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x
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x
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x
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x
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x
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x
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Appetite absent
|
|
|
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x
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Dyspepsia
|
Dyspepsia
|
common
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|
|
|
|
|
|
x
|
x
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x
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x
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|
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x
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Dyspnoea
|
Dyspnoea
|
common, 0-2%
|
|
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x
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x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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Dermatitis
|
Rash
|
common
|
|
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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Rash
|
Rash
|
common
|
|
|
x
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x
|
x
|
x
|
x
|
x
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x
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x
|
x
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x
|
x
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Hyperbilirubinaemia
|
Hyperbilirubinaemia
|
common
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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Hypoglycaemia
|
Hypoglycaemia
|
common, 0-2%
|
|
|
|
|
|
|
x
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x
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x
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x
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x
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Hypothyroidism
|
Hypothyroidism
|
common, 0-2%
|
|
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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Urinary tract infection
|
Urinary tract infection
|
0-6% - 6.14%
|
|
|
x
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x
|
x
|
x
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|
|
|
|
x
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x
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x
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Blood thyroid stimulating hormone decreased
|
Thyrotropin low
|
common
|
|
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|
|
|
|
x
|
x
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x
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x
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Glucose tolerance impaired
|
Glucose tolerance impaired
|
common
|
|
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x
|
x
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x
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x
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Cholelithiasis
|
Biliary sludge
|
common
|
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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Cholelithiasis
|
very common, 1% - 4.4%
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|
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|
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x
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x
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x
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x
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x
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x
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Thyroid disorder
|
Dysfunction thyroid
|
common
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|
|
|
|
|
|
x
|
x
|
x
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x
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Bradycardia
|
Bradycardia
|
common
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
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x
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x
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Transaminases increased
|
Transaminases increased
|
common
|
|
|
|
|
|
|
x
|
x
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x
|
x
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Thyroxine free decreased
|
Thyroxine free decreased
|
common
|
|
|
|
|
|
|
x
|
x
|
x
|
x
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|
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Nasopharyngitis
|
Cold symptoms
|
3.33% - 6.14%
|
|
|
x
|
x
|
x
|
x
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|
|
|
|
|
x
|
x
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Influenza
|
Flu symptoms
|
3.33% - 6.14%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Vomiting
|
Vomiting
|
common, 2.6% - 5%
|
1.82%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Arthralgia
|
Arthralgia
|
1.67% - 4.4%
|
3.64%
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
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Musculoskeletal discomfort
|
Arthralgia
|
1.67% - 4.4%
|
3.64%
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
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|
Myalgia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Back pain
|
Back pain
|
0.5% - 4.4%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Pruritus
|
Pruritus
|
common, 0-4% - 4.4%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Acne
|
Acne
|
3.33% - 4.4%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Steatorrhoea
|
Steatorrhoea
|
common, 3.6%
|
|
|
|
|
|
|
x
|
|
x
|
x
|
|
x
|
x
|
Alopecia
|
Alopecia
|
common, 1% - 3.51%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Muscle spasms
|
Cramps of lower extremities
|
3.51%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Cramp muscle
|
0-3% - 0-4%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Sinusitis
|
Sinusitis
|
0-4% - 3.51%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Contusion
|
Contusion
|
0.5% - 4.4%
|
1.82%
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Influenza like illness
|
Influenza-like symptoms
|
0-6%
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Arthritis
|
Arthritis
|
0-3% - 2.6%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Oedema
|
Oedema
|
1-3%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
Pollakiuria
|
Pollakiuria
|
1.67% - 3.51%
|
3.64%
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Cholecystitis
|
Cholecystitis
|
common, 0-2% - 1.8%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eructation
|
Eructation
|
0-2% - 1.8%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Haemorrhoids
|
Haemorrhoids
|
0-2% - 1.8%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Osteoarthritis
|
Osteoarthritis
|
0-2% - 1.8%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Arthropathy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Muscle twitching
|
Muscle twitching
|
0-2% - 1.8%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Anxiety
|
Anxiety
|
0.5-3%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Oropharyngeal discomfort
|
Throat sore
|
0.5-3%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Oropharyngeal pain
|
Throat sore
|
0.5-3%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Visual impairment
|
Visual disturbance
|
0.5-3%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Adrenal insufficiency
|
Adrenal insufficiency
|
0-3%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Infection
|
Infection
|
0-3%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Flushing
|
Flushing
|
0.5-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Dry mouth
|
Dry mouth
|
0.5-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Insomnia
|
Insomnia
|
0.5-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dysuria
|
Dysuria
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Epistaxis
|
Epistaxis
|
0-2%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Body temperature increased
|
Body temperature increased
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Pain in extremity
|
Foot pain
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypogonadism
|
Hypogonadism
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Irritability
|
Irritability
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Breast mass
|
Breast mass
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Nasal congestion
|
Nasal congestion
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypoaesthesia
|
Numbness
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Sensory loss
|
Numbness
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Polyuria
|
Polyuria
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Urine output increased
|
Polyuria
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Prostatitis
|
Prostatitis
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Tinnitus
|
Tinnitus
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Vulvovaginal pruritus
|
Vaginal itching
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Weight increased
|
Weight increased
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Renal pain
|
Renal pain
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Menopausal symptoms
|
Hot flush
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hot flush
|
Hot flush
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Breast neoplasm
|
Breast neoplasm
|
0-2%
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Dehydration
|
Dehydration
|
uncommon
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Tachycardia
|
Tachycardia
|
uncommon
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
Gastrointestinal haemorrhage
|
Gastrointestinal haemorrhage
|
0.5%
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Anorectal disorder
|
Rectal disorder
|
0.5%
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Pancreatitis acute
|
Pancreatitis acute
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Anaphylactic shock
|
Anaphylactic shock
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Anaphylactoid reaction
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Arrhythmia
|
Arrhythmia
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Cholestasis
|
Cholestasis
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Hypersensitivity
|
Hypersensitivity
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Immune system disorder
|
Immune system disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Intestinal obstruction
|
Intestinal obstruction
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Jaundice
|
Jaundice
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
Jaundice cholestatic
|
Jaundice cholestatic
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Thrombocytopenia
|
Thrombocytopenia
|
postmarketing
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
Urticaria
|
Urticaria
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
Hepatitis cholestatic
|
Hepatitis cholestatic
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Skin disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hepatobiliary disease
|
Hepatobiliary disease
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Hepatitis acute
|
Hepatitis acute
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Amenorrhoea
|
Amenorrhoea
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Amnesia
|
Amnesia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Anaemia
|
Anaemia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Hypochromic anaemia
|
Hypochromic anaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Appendicitis
|
Appendicitis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Asthma
|
Asthma
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Mental disorder
|
Mental disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Coagulopathy
|
Clotting
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Breast feeding
|
Breast feeding
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Bronchospasm
|
Bronchospasm
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Bronchitis
|
Bronchitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Neoplasm malignant
|
Neoplasm malignant
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Candida infection
|
Candida infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Basal cell carcinoma
|
Basal cell carcinoma
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Cellulitis
|
Cellulitis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Chest pain
|
Chest pain
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Conjunctivitis
|
Conjunctivitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Cough
|
Cough
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Acne cystic
|
Acne cystic
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Cystitis
|
Cystitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Bladder pain
|
Cystitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Cystitis noninfective
|
Cystitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Deafness
|
Deafness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hearing impaired
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Depression
|
Depression
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Diabetes insipidus
|
Diabetes insipidus
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Diabetes mellitus
|
Diabetes mellitus
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Diabetic
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Somnolence
|
Drowsiness
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Somnolence
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Ear disorder
|
Ear disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Endocrine disorder
|
Endocrine disorder
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
|
|
|
Extravasation
|
Extravasation
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Hepatic steatosis
|
Liver fatty
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Multiple fractures
|
Fracture
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Fracture
|
Fracture
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Gallbladder disorder
|
Gallbladder disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Gastritis
|
Gastritis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Gastroenteritis
|
Gastroenteritis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Gastrointestinal symptom NOS
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Goitre
|
Goitre
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Gynaecomastia
|
Gynaecomastia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Cardiac failure congestive
|
Cardiac failure congestive
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Haematuria
|
Haematuria
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Hepatitis
|
Hepatitis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Hernia
|
Hernia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Herpes simplex
|
Herpes simplex
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Herpes zoster
|
Herpes zoster
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hyperkalaemia
|
Hyperkalaemia
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Hypertension
|
Hypertension
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Hypertension worsened
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hypertensive
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Ischaemia
|
Ischaemia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Arthropathy
|
Arthropathy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Malabsorption
|
Malabsorption
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
|
|
Menstrual disorder
|
Menstrual disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Metrorrhagia
|
Metrorrhagia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Nail disorder
|
Nail disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Nervous system disorder
|
Nervous system disorder
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Nervousness
|
Nervousness
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Tension
|
Nervousness
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Neuralgia
|
Neuralgia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Neuritis
|
Neuritis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Neuropathy peripheral
|
Neuritis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Neuropathy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Oligomenorrhoea
|
Oligomenorrhoea
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Osteonecrosis
|
Osteonecrosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Ear infection
|
Otitis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
Otitis media
|
Otitis media
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Palpitations
|
Palpitations
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Pancreatitis
|
Pancreatitis
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Peptic ulcer
|
Peptic ulcer
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Petechiae
|
Petechiae
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Pharyngitis
|
Pharyngitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Phlebitis
|
Phlebitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Pituitary haemorrhage
|
Pituitary apoplexy
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Pneumonia
|
Pneumonia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Polymenorrhoea
|
Polymenorrhoea
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Pregnancy
|
Pregnancy
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
Prostatic disorder
|
Prostatic disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Pulmonary mass
|
Lung nodule
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Rhinitis
|
Rhinitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Convulsion
|
Convulsion
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Shock
|
Shock
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Syncope
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Status asthmaticus
|
Status asthmaticus
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Mouth ulceration
|
Ulcerative stomatitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Syncope
|
Syncope
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Loss of consciousness
|
Syncope
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Thrombophlebitis
|
Thrombophlebitis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Tremor
|
Tremor
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Upper respiratory tract infection
|
Upper respiratory tract infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Vaginal inflammation
|
Vaginal inflammation
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Vaginal infection
|
Vaginal inflammation
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Varicose vein
|
Varicose vein
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Vertigo
|
Vertigo
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Viral infection
|
Viral infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Weight decreased
|
Weight decreased
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Wheezing
|
Wheezing
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Injury
|
Trauma
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Sinus bradycardia
|
Sinus bradycardia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Burning sensation
|
Burning sensation
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Oedema peripheral
|
Oedema peripheral
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Blood creatine phosphokinase increased
|
Creatine phosphokinase increased
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Glucose tolerance decreased
|
Glucose tolerance decreased
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Injection site reaction
|
Injection site reaction
|
|
|
|
|
|
|
|
x
|
|
|
|
x
|
|
x
|
Muscular weakness
|
Muscular weakness
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Blood alkaline phosphatase increased
|
Phosphatase alkaline increased
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
|
|
x
|
Dry skin
|
Dry skin
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Otorrhoea
|
Otorrhoea
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Malnutrition
|
Malnutrition
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
Abdominal pain upper
|
Stomach ache
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Epigastric pain
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Malaise
|
Malaise
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Discomfort
|
Malaise
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Discomfort
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Feeling abnormal
|
Malaise
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Ill-defined disorder
|
Malaise
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Myalgia
|
Myalgia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
x
|
Abdominal tenderness
|
Abdominal tenderness
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Proctalgia
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Rectal tenesmus
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Anorectal discomfort
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Intraocular pressure increased
|
Intraocular pressure increased
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Seborrhoeic dermatitis
|
Oily skin
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Faeces discoloured
|
Faeces discoloured
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Galactorrhoea
|
Galactorrhoea
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Iron deficiency
|
Iron deficiency
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Gallbladder polyp
|
Gallbladder polyp
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Rectal haemorrhage
|
Rectal haemorrhage
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Blood growth hormone increased
|
Growth hormone overproduction
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Erythema
|
Redness
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Anaphylactoid reaction
|
Anaphylactoid reaction
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Vision blurred
|
Vision blurred
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
VIIth nerve paralysis
|
Bell's palsy
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
x
|
x
|
Nephrolithiasis
|
Nephrolithiasis
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Agitation
|
Hyperkinesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Increased activity
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Hyperkinesia
|
Hyperkinesia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Pruritus generalised
|
Pruritus generalised
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Injection site haematoma
|
Injection site haematoma
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Breast pain
|
Breast pain female
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Drug interaction
|
Drug interaction
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
Hyperhidrosis
|
Sweating increased
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Sleep disorder
|
Sleep disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Local reaction
|
Local reaction
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
x
|
Joint effusion
|
Joint effusion
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Hearing impaired
|
Hearing impaired
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Psychotic disorder
|
Paranoia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Paranoia
|
Paranoia
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Paraesthesia
|
Tingling sensation
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Loss of libido
|
Loss of libido
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 2 |
Source: | FDA |
---|
Side effects: | 91 |
Source: | FDA |
---|
Side effects: | 94 |
Source: | FDA Structured Product Label |
---|
Side effects: | 95 |
Source: | FDA Structured Product Label |
---|
Side effects: | 95 |
Source: | FDA Structured Product Label |
---|
Side effects: | 59 |
Source: | medicines.org.au |
---|
Side effects: | 60 |
Source: | Medsafe |
---|
Side effects: | 63 |
Source: | Medsafe |
---|
Side effects: | 64 |
Source: | medicines.org.au |
---|
Side effects: | 77 |
Source: | BC Cancer |
---|
Side effects: | 119 |
Source: | Health Canada |
---|
Side effects: | 170 |
Source: | Health Canada |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|