Guanfacine
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
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3
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4
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Dry mouth
|
Dry mouth
|
postmarketing, 2% - 60%
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0% - 6.85%
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x
|
x
|
x
|
x
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Somnolence
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Somnolence
|
postmarketing, 18% - 38%
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1.37% - 12%
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x
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x
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x
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x
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Drowsiness
|
6% - 33%
|
|
|
x
|
x
|
x
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Dizziness
|
Dizziness
|
postmarketing, 1% - 15%
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2.74% - 8%
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x
|
x
|
x
|
x
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Syncope
|
postmarketing
|
|
x
|
x
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x
|
x
|
Asthenia
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Fatigue
|
postmarketing, 2% - 14%
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2% - 4.11%
|
x
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x
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x
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x
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Asthenia
|
postmarketing, 1% - 5%
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0%
|
x
|
x
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x
|
x
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Fatigue
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Fatigue
|
postmarketing, 2% - 14%
|
2% - 4.11%
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x
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x
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x
|
x
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Decreased appetite
|
Decreased appetite
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5% - 7%
|
3% - 4%
|
x
|
|
|
|
Irritability
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Irritability
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6%
|
4%
|
x
|
|
|
|
Lethargy
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Lethargy
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6%
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3%
|
x
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|
|
|
Constipation
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Constipation
|
postmarketing, 2% - 14%
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0% - 1%
|
x
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x
|
x
|
x
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Headache
|
Headache
|
postmarketing, 0.2% - 24%
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4.11% - 19%
|
x
|
x
|
x
|
x
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Hypotension
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Hypotension
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3% - 7%
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0% - 3%
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x
|
|
|
|
Insomnia
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Insomnia
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postmarketing, 0% - 12%
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6%
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x
|
x
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x
|
x
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Affect lability
|
Affect lability
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2%
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1%
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x
|
|
|
|
Abdominal pain
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Abdominal pain
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postmarketing, 10% - 11%
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3% - 9%
|
x
|
x
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x
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x
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Gastrointestinal pain
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Abdominal pain
|
postmarketing, 10% - 11%
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3% - 9%
|
x
|
x
|
x
|
x
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Alopecia
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Alopecia
|
postmarketing
|
|
x
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x
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x
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x
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Anxiety
|
Anxiety
|
postmarketing
|
|
x
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x
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x
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x
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Arthralgia
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Arthralgia
|
postmarketing
|
|
x
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x
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x
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x
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Musculoskeletal discomfort
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Arthralgia
|
postmarketing
|
|
x
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x
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x
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x
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Myalgia
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postmarketing
|
|
x
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x
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x
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x
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Chest pain
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Chest pain
|
postmarketing
|
|
x
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x
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x
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x
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Retrosternal pain
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|
|
|
x
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x
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x
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Confusional state
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Confusional state
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postmarketing
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|
x
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x
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x
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x
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Feeling abnormal
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Confusional state
|
postmarketing
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|
x
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x
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x
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x
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Malaise
|
postmarketing
|
|
x
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x
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x
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x
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Dermatitis
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Dermatitis
|
postmarketing
|
|
x
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x
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x
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x
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Rash
|
postmarketing
|
|
x
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x
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x
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x
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Dermatitis exfoliative
|
Dermatitis exfoliative
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postmarketing
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|
x
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x
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x
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x
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Diarrhoea
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Diarrhoea
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postmarketing, 4%
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1%
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x
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x
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x
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x
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Dysgeusia
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Dysgeusia
|
postmarketing
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|
x
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x
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x
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x
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Dyspepsia
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Dyspepsia
|
postmarketing
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|
x
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x
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x
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x
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Dyspnoea
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Dyspnoea
|
postmarketing
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|
x
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x
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x
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x
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Oedema
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Oedema
|
postmarketing
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|
x
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x
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x
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x
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Rash
|
Rash
|
postmarketing
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|
x
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x
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x
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x
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Eye disorder
|
Eye disorder
|
postmarketing
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|
x
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x
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x
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x
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Hallucination
|
Hallucination
|
postmarketing
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|
x
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|
|
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Atrioventricular block
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Block heart
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postmarketing
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|
|
x
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x
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x
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Atrioventricular block
|
|
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x
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|
|
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Cardiac failure congestive
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Cardiac failure congestive
|
postmarketing
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|
|
x
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x
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x
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Renal failure acute
|
Renal failure acute
|
postmarketing
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|
|
x
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x
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x
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Muscle spasms
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Cramps of lower extremities
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postmarketing
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|
x
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x
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x
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x
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Pain in extremity
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Leg pain
|
postmarketing
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|
x
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x
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x
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x
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Myocardial infarction
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Myocardial infarction
|
postmarketing
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|
|
x
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x
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x
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Acute coronary syndrome
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Myocardial infarction
|
postmarketing
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|
|
x
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x
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x
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Nausea
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Nausea
|
postmarketing, 5% - 6%
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2% - 3%
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x
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x
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x
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x
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Nervousness
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Nervousness
|
postmarketing
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|
|
x
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x
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x
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Tension
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Nervousness
|
postmarketing
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|
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x
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x
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x
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Nocturia
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Nocturia
|
postmarketing
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|
|
x
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x
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x
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Palpitations
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Palpitations
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postmarketing
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|
x
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x
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x
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x
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Paraesthesia
|
Paraesthesia
|
postmarketing
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|
x
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x
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x
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x
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Pruritus
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Pruritus
|
postmarketing
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|
x
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x
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x
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x
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Cerebrovascular accident
|
Cerebrovascular accident
|
postmarketing
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|
|
x
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x
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x
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Shock
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Syncope
|
postmarketing
|
|
x
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x
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x
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x
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Syncope
|
Syncope
|
postmarketing
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|
x
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x
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x
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x
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Loss of consciousness
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Syncope
|
postmarketing
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|
x
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x
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x
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x
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Tachycardia
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Tachycardia
|
postmarketing
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|
x
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x
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x
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x
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Tremor
|
Tremor
|
postmarketing
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|
x
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x
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x
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x
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Pollakiuria
|
Pollakiuria
|
postmarketing
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|
x
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x
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x
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x
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Vertigo
|
Vertigo
|
postmarketing
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|
x
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x
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x
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x
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Agitation
|
Agitation
|
postmarketing
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|
x
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x
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x
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x
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Liver function test abnormal
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Liver function test abnormal
|
postmarketing
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|
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x
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x
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x
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Malaise
|
Malaise
|
postmarketing
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|
x
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x
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x
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x
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Discomfort
|
Malaise
|
postmarketing
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|
x
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x
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x
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x
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Ill-defined disorder
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Malaise
|
postmarketing
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|
x
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x
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x
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x
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Myalgia
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Myalgia
|
postmarketing
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|
x
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x
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x
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x
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Cardiac fibrillation
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Cardiac fibrillation
|
postmarketing
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|
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x
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x
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x
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Erectile dysfunction
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Erectile dysfunction
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postmarketing
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0% - 1.37%
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x
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x
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x
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x
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Vision blurred
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Vision blurred
|
postmarketing
|
|
x
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x
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x
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x
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Bradycardia
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Bradycardia
|
postmarketing, 2%
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0%
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x
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x
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x
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x
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Amnesia
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Amnesia
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|
|
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x
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x
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x
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Sinus arrhythmia
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Sinus arrhythmia
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|
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x
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|
|
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Asthma
|
Asthma
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|
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x
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|
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Conjunctivitis
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Conjunctivitis
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|
|
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x
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x
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x
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Dysphagia
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Dysphagia
|
|
|
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x
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x
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x
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Enuresis
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Enuresis
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|
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x
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|
|
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Hypersensitivity
|
Hypersensitivity
|
|
|
x
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|
|
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Orthostatic hypotension
|
Orthostatic hypotension
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|
|
x
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x
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x
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x
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Immune system disorder
|
Immune system disorder
|
|
|
x
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|
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Iritis
|
Iritis
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|
|
|
x
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x
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x
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Nightmare
|
Nightmare
|
|
|
x
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x
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x
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x
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Pallor
|
Pallor
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|
|
x
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|
|
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Paresis
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Paresis
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|
|
|
x
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x
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x
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Purpura
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Purpura
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|
|
|
x
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x
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x
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Vascular purpura
|
Purpura
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|
|
|
x
|
x
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x
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Rhinitis
|
Rhinitis
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|
|
|
x
|
x
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x
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Convulsion
|
Convulsion
|
|
|
x
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|
|
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Hyperhidrosis
|
Sweating
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|
|
|
x
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x
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x
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Testicular disorder
|
Testicular disorder
|
|
|
|
x
|
x
|
x
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Tinnitus
|
Tinnitus
|
|
|
|
x
|
x
|
x
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Urinary incontinence
|
Urinary incontinence
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|
|
|
x
|
x
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x
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Vomiting
|
Vomiting
|
|
|
x
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|
|
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Weight increased
|
Weight increased
|
|
|
x
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|
|
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Hypokinesia
|
Hypokinesia
|
|
|
|
x
|
x
|
x
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Alanine aminotransferase increased
|
Alanine aminotransferase increased
|
|
|
x
|
|
|
|
Abdominal pain upper
|
Abdominal pain upper
|
|
|
x
|
|
|
|
Abdominal pain lower
|
Abdominal pain lower
|
|
|
x
|
|
|
|
Abdominal discomfort
|
Upset stomach
|
|
|
x
|
|
|
|
Skin exfoliation
|
Skin exfoliation
|
|
|
|
x
|
x
|
x
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Initial insomnia
|
Initial insomnia
|
|
|
x
|
|
|
|
Middle insomnia
|
Middle insomnia
|
|
|
x
|
|
|
|
Hypertension
|
Hypertensive
|
|
|
|
x
|
x
|
x
|
Hypersomnia
|
Hypersomnia
|
|
|
x
|
|
|
|
Loss of libido
|
Loss of libido
|
|
|
|
x
|
x
|
x
|
Visual impairment
|
Visual impairment
|
|
|
|
x
|
x
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 65 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Side effects: | 69 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|