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Bexarotene

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX25

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Malnutrition Malnutrition 78.6% - 79.2% x x x x
Pruritus Pruritus very common, 18% - 40% x x x x x x x
Hypercholesterolaemia Hypercholesterolaemia very common, 0% - 62.3% x x x x x
Pain Pain very common, 12% - 40% x x x x
Hypothyroidism Hypothyroidism very common, 0% - 52.8% x x x x x
Dermatitis Rash very common, 0% - 78% x x x x x x x
Dermatitis x
Rash Rash very common, 0% - 78% x x x x x x x
Headache Headache very common, 0% - 41.5% x x x x x x x
Asthenia Asthenia 0% - 45.3% x x x x x x x
Fatigue x x x x
Skin disorder Skin disorder common, 18% - 26% x x x
Unspecified disorder of skin and subcutaneous tissue x
Leukopenia Leukopenia very common, 0% - 47.2% x x x x x x x
Nausea Nausea 7.55% - 16% x x x x
Infection Infection common, 0% - 22.6% x x x x x x x
Dermatitis contact Dermatitis contact 8% - 14% x x x
Dermatitis irritant contact x
Dry skin Dry skin 9.43% - 11% x x x x
Hyperlipidaemia Hyperlipidaemia very common, 0% - 79.2% x x x x x x x
Chills Chills 9.52% - 13.2% x x x x
Cataract Cataract uncommon, 19% x x
Dermatitis exfoliative Dermatitis exfoliative very common, 0% - 28.3% x x x x x x x
Hypochromic anaemia Hypochromic anaemia 3.57% - 13.2% x x x
Abdominal pain Abdominal pain common, 3.77% - 11% x x x x x
Gastrointestinal pain Abdominal pain common, 3.77% - 11% x x x x x
Diarrhoea Diarrhoea 1% - 41.5% x x x x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased common, 7.14% - 13.2% x x x x
Anaemia Anaemia 5.95% - 24.5% x x x x
Paraesthesia Paraesthesia 6% x x x
Oedema peripheral Oedema peripheral common, 0% - 13.1% x x x x x x x
Tachycardia Tachycardia uncommon, 10% x x x x x
Albuminuria Albuminuria 10% x x x x
Angina pectoris Angina pectoris 10% x x x x
Arthralgia Arthralgia common, 10% x x x x x
Musculoskeletal discomfort Arthralgia common, 10% x x x x x
Myalgia common, 10% x x x x x
Bronchitis Bronchitis 10% x x x x
Cheilitis Cheilitis 10% x x x x
Chest pain Chest pain 10% x x x x x
Colitis Colitis 10% x x x x
Confusional state Confusional state 10% x x x x x
Feeling abnormal Confusional state 10% x x x x x
Malaise x
Conjunctivitis Conjunctivitis 10% x x x x
Constipation Constipation common, 10% x x x x x
Cough Cough 10% x
Cough increased 0% - 6% x x x x x x
Deafness Deafness common x
Dizziness Dizziness common, 10% x x x x x
Syncope 10% x x x x
Dyspepsia Dyspepsia 10% x x x x x
Dyspnoea Dyspnoea 10% x x x x x
Dysuria Dysuria 10% x x x x
Ear pain Ear pain 10% x x x x
Eosinophilia Eosinophilia 10% x x x x
Eye disorder Eye disorder common x
Body temperature increased Body temperature increased 4.76% - 17% x x x x
Flatulence Flatulence common, 10% x x x x x
Gastroenteritis Gastroenteritis 10% x x x x
Gingivitis Gingivitis 10% x x x x x
Haematuria Haematuria 10% x x x x x
Haemoptysis Haemoptysis 10% x x x x x
Hypersensitivity Hypersensitivity common x x x x x
Hypoaesthesia Hypoaesthesia common, 10% x x x x x
Hypoproteinaemia Hypoproteinaemia common, 10% x x x x x
Arthropathy Arthropathy 10% x x x x x
Osteoarthritis Arthropathy 10% x x x x x
Keratitis Keratitis 10% x x x x
Breast pain Breast pain 10% x x x x
Melaena Melaena 10% x x x x x
Otitis externa Otitis externa 10% x x x x
Pleural effusion Pleural effusion 10% x x x x
Pulmonary oedema Pulmonary oedema 10% x x x x
Rhinitis Rhinitis 10% x x x x x
Skin mass Skin nodule common, 10% x x x x x
Skin ulcer Skin ulcer common, 10% x x x x x
Cerebrovascular accident Cerebrovascular accident 10% x x x x
Shock Syncope 10% x x x x
Syncope Syncope 10% x x x x
Loss of consciousness Syncope 10% x x x x
Thrombocytopenia Thrombocytopenia 10% x x x x
Thyroid disorder Thyroid disorder common x
Urinary incontinence Urinary incontinence 10% x x x x
Urinary tract infection Urinary tract infection 10% x x x x
Weight increased Weight increased common, 10% x x x x x
Weight decreased Weight decreased 10% x x x x x
Dry mouth Dry mouth 10% x x x x
Pollakiuria Micturition urgency 10% x x x x
Micturition urgency Micturition urgency 10% x x x x
Coagulation time prolonged Coagulation time prolonged 10% x x x x
Blood creatinine increased Creatinine increased common x x x x
Skin hypertrophy Skin hypertrophy common x
Liver function test abnormal Liver function test abnormal common x
Bone pain Bone pain common, 10% x x x x x
Pseudolymphoma Pseudolymphoma common x
Myalgia Myalgia common, 10% x x x x x
Right ventricular failure Cardiac failure right 10% x x x x
Sepsis Sepsis 10% x x x x
Dry eye Dry eye common, 10% x x x x x
Acne Acne common x
Insomnia Insomnia common, 4.76% - 11.3% x x x x x
Muscular weakness Myasthenia 10% x x x x
Alopecia Alopecia 3.57% - 11.3% x x x x
Influenza Influenza 3.57% - 13.2% x x x x x
Pneumonia Pneumonia 2% - 3.8% x x x x x
Vomiting Vomiting common, 0% - 13.2% x x x x x
Ataxia Ataxia uncommon, 10% x x x x x
Blepharitis Blepharitis uncommon, 10% x x x x x
Cellulitis Cellulitis uncommon, 10% x x x x x
Hyperaesthesia Hyperaesthesia uncommon, 10% x x x x x
Hypertension Hypertension uncommon, 10% x x x x x
Lymphocytosis Lymphocytosis uncommon, 10% x x x x x
Scotoma Scotoma uncommon, 10% x x x x x
Agitation Agitation uncommon, 10% x x x x x
Corneal lesion Corneal lesion uncommon, 10% x x x x x
Neuropathy peripheral Neuropathy uncommon, 10% x x x x x
Neuritis x
Thrombocytosis Thrombocytosis uncommon, 10% x x x x x
Pharyngitis Pharyngitis 0% - 6% x x x x x x x
Hyperhidrosis Sweating common, 0% - 6% x x x
Lymphadenopathy Lymphadenopathy common, 0% - 6% x x x
Decreased appetite Anorexia 0% - 22.6% x x x x
Back pain Back pain 2% - 11.3% x x x x
Bacterial infection Bacterial infection 0% - 13.2% x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased common, 0% - 3.77% x x x x
Alanine aminotransferase increased Alanine aminotransferase increased common, 0% - 3.77% x x x x
Coagulopathy Coagulopathy uncommon x
Ear disorder Ear disorder uncommon x
Gout Gout uncommon x
Blood disorder Blood disorder uncommon x
Haemorrhage Haemorrhage uncommon x x x x x
Haemoglobin Haemorrhage uncommon x x x x x
Herpes simplex Herpes simplex uncommon x
Hyperthyroidism Hyperthyroidism uncommon x
Neoplasm Neoplasm uncommon x
Purpura Purpura uncommon x
Vascular purpura Purpura uncommon x
Varicose vein Varicose vein uncommon x
Vertigo Vertigo uncommon x
Hepatic failure Hepatic failure uncommon x x x x
Rash pustular Rash pustular uncommon x x x x
High density lipoprotein decreased High density lipoprotein decreased uncommon x x x x
Renal impairment Kidney function abnormal uncommon x x x x
Laboratory test abnormal Laboratory test abnormal uncommon x
Infection parasitic Infection parasitic uncommon x
Pancreatitis acute Pancreatitis acute x x x x
Anxiety Anxiety x
Arrhythmia Arrhythmia x x
Arthritis Arthritis x
Candida infection Oral candidiasis x
Oral candidiasis Oral candidiasis x
Neoplasm malignant Carcinoma x
Cholecystitis Cholecystitis x
Connective tissue disorder Connective tissue disorder x
Libido decreased Libido decreased x
Disturbance in sexual arousal Libido decreased x
Dysphagia Dysphagia x
Dehydration Dehydration x
Dysgeusia Dysgeusia x
Ecchymosis Ecchymosis x
Oedema Oedema 0% - 10% x x
Endocrine disorder Endocrine disorder x
Epistaxis Epistaxis x
Eructation Eructation x
Excoriation Excoriation x
Fasting Fasting x
Fatigue Fatigue x x x x
Furuncle Furunculosis x
Gastrointestinal disorder Gastrointestinal disorder x
Cardiac disorder Cardiac disorder x
Cardiac failure congestive Cardiac failure congestive x
Subdural haematoma Subdural haematoma x x x x
Herpes zoster Herpes zoster x
Hyperbilirubinaemia Hyperbilirubinaemia 0% - 3.77% x x x x
Hypercalcaemia Hypercalcaemia x
Hyperglycaemia Hyperglycaemia 0% - 5.7% x x x x
Hyperkalaemia Hyperkalaemia 0% - 1.9% x x x
Hypernatraemia Hypernatraemia 0% - 1.2% x x x
Hypertriglyceridaemia Hypertriglyceridaemia x x x x x
Blood triglycerides increased Hypertriglyceridaemia x x x x x
Hypocalcaemia Hypocalcaemia 0% - 1.2% x x x
Hypokalaemia Hypokalaemia x
Hyponatraemia Hyponatraemia 0% - 9.4% x x x x
Jaundice Jaundice x
Jaundice cholestatic Jaundice cholestatic x
Lacrimal disorder Lacrimal disorder x
Lacrimal structural disorder Lacrimal disorder x
Laryngospasm Laryngospasm x
Muscle spasms Cramps of lower extremities x
Muscle spasms x x x x
Lethargy Lethargy x x x x
Lung disorder Lung disorder x
Hypertonia Hypertonia x
Nervous system disorder Nervous system disorder x
Nervousness Nervousness x
Tension Nervousness x
Neuritis Neuritis x
Neutropenia Neutropenia x x x x
Night blindness Night blindness x
Nocturia Nocturia x
Nystagmus Nystagmus x
Pallor Pallor x
Palpitations Palpitations x
Pancreatitis Pancreatitis 0% - 5.66% x x x x
Pelvic pain Pelvic pain x
Petechiae Petechiae x
Pleural disorder Pleural disorder x
Polyuria Polyuria x
Urine output increased Polyuria x
Psoriasis Psoriasis x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Sinusitis Sinusitis x
Stomatitis Stomatitis x
Mouth ulceration x
Thirst Thirst x
Tinnitus Tinnitus x
Erythema Erythema x
Redness x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x
Viral infection Viral infection x
Urinary retention Urinary retention x
Peripheral vascular disorder Peripheral vascular disorder x
Skin odour abnormal Body odor x
Stupor Stupor x
Depressed level of consciousness Stupor x
Mood swings Mood swings x
Affect lability Mood swings x
Mouth ulceration Mouth ulceration x
Migraine Migraine x
Amylase increased Amylase increased x x x x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Hypocholesterolaemia Hypocholesterolaemia x
Hypomagnesaemia Hypomagnesaemia x
Hepatocellular injury Hepatocellular injury x
Liver injury Hepatocellular injury x
Pancytopenia Bone marrow depression x
Eye pain Eye pain x
Paraesthesia oral Circumoral paresthesia x
Blood alkaline phosphatase increased Phosphatase alkaline increased x
Blood thromboplastin decreased Thromboplastin decreased x
White blood cell disorder WBC abnormal NOS 0% - 6% x x x
Vascular anomaly Vascular anomaly x
Abnormal faeces Abnormal faeces x
Photosensitivity reaction Photosensitivity reaction x
Lichenoid keratosis Eruption lichenoid x
Malaise Malaise x
Discomfort Malaise x
Ill-defined disorder Malaise x
Increased appetite Increased appetite x
Proctalgia Rectal tenesmus x
Rectal tenesmus Rectal tenesmus x
Anorectal discomfort Rectal tenesmus x
Thinking abnormal Thinking abnormal x
Mental disability Thinking abnormal x
Urine abnormality Urine abnormality x
Urine analysis abnormal Urine abnormality x
Dermatitis bullous Rash bullous x x x
Erectile dysfunction Erectile dysfunction x
Hypolipidaemia Hypolipidaemia x
Abdominal distension Enlargement abdomen x
Rash maculo-papular Rash maculo-papular 0% - 6% x x x
Face oedema Face oedema x
Hypovolaemia Hypovolaemia x
Lipase increased Lipase increased x
Gait disturbance Gait disturbance x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Febrile neutropenia Febrile neutropenia x
Rash papular Rash papular x x x
Breast enlargement Breast enlargement x
Somnolence Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

bexarotene

Side effects:20
Source:FDA Structured Product Label

BEXAROTENE / TARGRETIN

Side effects:25
Source:FDA

Bexarotene

Side effects:103
Source:BC Cancer

BEXAROTENE / TARGRETIN

Side effects:118
Source:FDA

BEXAROTENE

Side effects:118
Source:FDA Structured Product Label

BEXAROTENE / TARGRETIN

Side effects:118
Source:FDA

bexarotene / bexarotene

Side effects:186
Source:EMA

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label