MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
Malnutrition
|
Malnutrition
|
78.6% - 79.2%
|
|
|
|
|
x
|
x
|
x
|
x
|
Pruritus
|
Pruritus
|
very common, 18% - 40%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypercholesterolaemia
|
Hypercholesterolaemia
|
very common, 0% - 62.3%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Pain
|
Pain
|
very common, 12% - 40%
|
|
x
|
x
|
x
|
|
|
|
x
|
Hypothyroidism
|
Hypothyroidism
|
very common, 0% - 52.8%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Dermatitis
|
Rash
|
very common, 0% - 78%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis
|
|
|
|
x
|
|
|
|
|
|
Rash
|
Rash
|
very common, 0% - 78%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Headache
|
Headache
|
very common, 0% - 41.5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
Asthenia
|
0% - 45.3%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Fatigue
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Skin disorder
|
Skin disorder
|
common, 18% - 26%
|
|
x
|
x
|
|
|
|
|
x
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
|
|
|
|
|
|
x
|
Leukopenia
|
Leukopenia
|
very common, 0% - 47.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Nausea
|
Nausea
|
7.55% - 16%
|
|
|
|
x
|
x
|
x
|
x
|
|
Infection
|
Infection
|
common, 0% - 22.6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis contact
|
Dermatitis contact
|
8% - 14%
|
|
x
|
x
|
|
|
|
|
x
|
Dermatitis irritant contact
|
|
|
|
x
|
|
|
|
|
|
Dry skin
|
Dry skin
|
9.43% - 11%
|
|
|
|
x
|
x
|
x
|
x
|
|
Hyperlipidaemia
|
Hyperlipidaemia
|
very common, 0% - 79.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Chills
|
Chills
|
9.52% - 13.2%
|
|
|
|
x
|
x
|
x
|
x
|
|
Cataract
|
Cataract
|
uncommon, 19%
|
|
|
|
x
|
|
|
|
x
|
Dermatitis exfoliative
|
Dermatitis exfoliative
|
very common, 0% - 28.3%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypochromic anaemia
|
Hypochromic anaemia
|
3.57% - 13.2%
|
|
|
|
|
x
|
x
|
x
|
|
Abdominal pain
|
Abdominal pain
|
common, 3.77% - 11%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal pain
|
Abdominal pain
|
common, 3.77% - 11%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Diarrhoea
|
Diarrhoea
|
1% - 41.5%
|
|
|
|
x
|
x
|
x
|
x
|
|
Blood lactate dehydrogenase increased
|
Lactic dehydrogenase activity increased
|
common, 7.14% - 13.2%
|
|
|
|
|
x
|
x
|
x
|
x
|
Anaemia
|
Anaemia
|
5.95% - 24.5%
|
|
|
|
x
|
x
|
x
|
x
|
|
Paraesthesia
|
Paraesthesia
|
6%
|
|
x
|
x
|
|
|
|
|
x
|
Oedema peripheral
|
Oedema peripheral
|
common, 0% - 13.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Tachycardia
|
Tachycardia
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Albuminuria
|
Albuminuria
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Angina pectoris
|
Angina pectoris
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Arthralgia
|
Arthralgia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Musculoskeletal discomfort
|
Arthralgia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Myalgia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Bronchitis
|
Bronchitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Cheilitis
|
Cheilitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Chest pain
|
Chest pain
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Colitis
|
Colitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Confusional state
|
Confusional state
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Feeling abnormal
|
Confusional state
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Malaise
|
|
|
|
|
|
|
|
|
x
|
Conjunctivitis
|
Conjunctivitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Constipation
|
Constipation
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Cough
|
Cough
|
10%
|
|
|
|
x
|
|
|
|
|
Cough increased
|
0% - 6%
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
Deafness
|
Deafness
|
common
|
|
|
|
|
|
|
|
x
|
Dizziness
|
Dizziness
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Dyspepsia
|
Dyspepsia
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Dyspnoea
|
Dyspnoea
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Dysuria
|
Dysuria
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Ear pain
|
Ear pain
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Eosinophilia
|
Eosinophilia
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Eye disorder
|
Eye disorder
|
common
|
|
|
|
|
|
|
|
x
|
Body temperature increased
|
Body temperature increased
|
4.76% - 17%
|
|
|
|
x
|
x
|
x
|
x
|
|
Flatulence
|
Flatulence
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Gastroenteritis
|
Gastroenteritis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Gingivitis
|
Gingivitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Haematuria
|
Haematuria
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Haemoptysis
|
Haemoptysis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypersensitivity
|
Hypersensitivity
|
common
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypoaesthesia
|
Hypoaesthesia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypoproteinaemia
|
Hypoproteinaemia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Arthropathy
|
Arthropathy
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Osteoarthritis
|
Arthropathy
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Keratitis
|
Keratitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Breast pain
|
Breast pain
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Melaena
|
Melaena
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Otitis externa
|
Otitis externa
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Pleural effusion
|
Pleural effusion
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Pulmonary oedema
|
Pulmonary oedema
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Rhinitis
|
Rhinitis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Skin mass
|
Skin nodule
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Skin ulcer
|
Skin ulcer
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Cerebrovascular accident
|
Cerebrovascular accident
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Shock
|
Syncope
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Syncope
|
Syncope
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Loss of consciousness
|
Syncope
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Thrombocytopenia
|
Thrombocytopenia
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Thyroid disorder
|
Thyroid disorder
|
common
|
|
|
|
|
|
|
|
x
|
Urinary incontinence
|
Urinary incontinence
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Urinary tract infection
|
Urinary tract infection
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Weight increased
|
Weight increased
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Weight decreased
|
Weight decreased
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Dry mouth
|
Dry mouth
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Pollakiuria
|
Micturition urgency
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Micturition urgency
|
Micturition urgency
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Coagulation time prolonged
|
Coagulation time prolonged
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Blood creatinine increased
|
Creatinine increased
|
common
|
|
|
|
|
x
|
x
|
x
|
x
|
Skin hypertrophy
|
Skin hypertrophy
|
common
|
|
|
|
|
|
|
|
x
|
Liver function test abnormal
|
Liver function test abnormal
|
common
|
|
|
|
|
|
|
|
x
|
Bone pain
|
Bone pain
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Pseudolymphoma
|
Pseudolymphoma
|
common
|
|
|
|
|
|
|
|
x
|
Myalgia
|
Myalgia
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Right ventricular failure
|
Cardiac failure right
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Sepsis
|
Sepsis
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Dry eye
|
Dry eye
|
common, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Acne
|
Acne
|
common
|
|
|
|
|
|
|
|
x
|
Insomnia
|
Insomnia
|
common, 4.76% - 11.3%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Muscular weakness
|
Myasthenia
|
10%
|
|
|
|
x
|
x
|
x
|
x
|
|
Alopecia
|
Alopecia
|
3.57% - 11.3%
|
|
|
|
x
|
x
|
x
|
x
|
|
Influenza
|
Influenza
|
3.57% - 13.2%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Pneumonia
|
Pneumonia
|
2% - 3.8%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Vomiting
|
Vomiting
|
common, 0% - 13.2%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Ataxia
|
Ataxia
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Blepharitis
|
Blepharitis
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Cellulitis
|
Cellulitis
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hyperaesthesia
|
Hyperaesthesia
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypertension
|
Hypertension
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Lymphocytosis
|
Lymphocytosis
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Scotoma
|
Scotoma
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Agitation
|
Agitation
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Corneal lesion
|
Corneal lesion
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Neuropathy peripheral
|
Neuropathy
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Neuritis
|
|
|
|
|
|
|
|
|
x
|
Thrombocytosis
|
Thrombocytosis
|
uncommon, 10%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Pharyngitis
|
Pharyngitis
|
0% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hyperhidrosis
|
Sweating
|
common, 0% - 6%
|
|
x
|
x
|
|
|
|
|
x
|
Lymphadenopathy
|
Lymphadenopathy
|
common, 0% - 6%
|
|
x
|
x
|
|
|
|
|
x
|
Decreased appetite
|
Anorexia
|
0% - 22.6%
|
|
|
|
x
|
x
|
x
|
x
|
|
Back pain
|
Back pain
|
2% - 11.3%
|
|
|
|
x
|
x
|
x
|
x
|
|
Bacterial infection
|
Bacterial infection
|
0% - 13.2%
|
|
|
|
|
x
|
x
|
x
|
|
Aspartate aminotransferase increased
|
Aspartate aminotransferase increased
|
common, 0% - 3.77%
|
|
|
|
|
x
|
x
|
x
|
x
|
Alanine aminotransferase increased
|
Alanine aminotransferase increased
|
common, 0% - 3.77%
|
|
|
|
|
x
|
x
|
x
|
x
|
Coagulopathy
|
Coagulopathy
|
uncommon
|
|
|
|
|
|
|
|
x
|
Ear disorder
|
Ear disorder
|
uncommon
|
|
|
|
|
|
|
|
x
|
Gout
|
Gout
|
uncommon
|
|
|
|
|
|
|
|
x
|
Blood disorder
|
Blood disorder
|
uncommon
|
|
|
|
|
|
|
|
x
|
Haemorrhage
|
Haemorrhage
|
uncommon
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Haemoglobin
|
Haemorrhage
|
uncommon
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Herpes simplex
|
Herpes simplex
|
uncommon
|
|
|
|
|
|
|
|
x
|
Hyperthyroidism
|
Hyperthyroidism
|
uncommon
|
|
|
|
|
|
|
|
x
|
Neoplasm
|
Neoplasm
|
uncommon
|
|
|
|
|
|
|
|
x
|
Purpura
|
Purpura
|
uncommon
|
|
|
|
|
|
|
|
x
|
Vascular purpura
|
Purpura
|
uncommon
|
|
|
|
|
|
|
|
x
|
Varicose vein
|
Varicose vein
|
uncommon
|
|
|
|
|
|
|
|
x
|
Vertigo
|
Vertigo
|
uncommon
|
|
|
|
|
|
|
|
x
|
Hepatic failure
|
Hepatic failure
|
uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
Rash pustular
|
Rash pustular
|
uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
High density lipoprotein decreased
|
High density lipoprotein decreased
|
uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
Renal impairment
|
Kidney function abnormal
|
uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
Laboratory test abnormal
|
Laboratory test abnormal
|
uncommon
|
|
|
|
|
|
|
|
x
|
Infection parasitic
|
Infection parasitic
|
uncommon
|
|
|
|
|
|
|
|
x
|
Pancreatitis acute
|
Pancreatitis acute
|
|
|
|
|
|
x
|
x
|
x
|
x
|
Anxiety
|
Anxiety
|
|
|
|
|
|
|
|
|
x
|
Arrhythmia
|
Arrhythmia
|
|
|
|
|
x
|
|
|
|
x
|
Arthritis
|
Arthritis
|
|
|
|
|
|
|
|
|
x
|
Candida infection
|
Oral candidiasis
|
|
|
|
|
|
|
|
|
x
|
Oral candidiasis
|
Oral candidiasis
|
|
|
|
|
|
|
|
|
x
|
Neoplasm malignant
|
Carcinoma
|
|
|
|
|
|
|
|
|
x
|
Cholecystitis
|
Cholecystitis
|
|
|
|
|
|
|
|
|
x
|
Connective tissue disorder
|
Connective tissue disorder
|
|
|
|
|
|
|
|
|
x
|
Libido decreased
|
Libido decreased
|
|
|
|
|
|
|
|
|
x
|
Disturbance in sexual arousal
|
Libido decreased
|
|
|
|
|
|
|
|
|
x
|
Dysphagia
|
Dysphagia
|
|
|
|
|
|
|
|
|
x
|
Dehydration
|
Dehydration
|
|
|
|
|
|
|
|
|
x
|
Dysgeusia
|
Dysgeusia
|
|
|
|
|
|
|
|
|
x
|
Ecchymosis
|
Ecchymosis
|
|
|
|
|
|
|
|
|
x
|
Oedema
|
Oedema
|
0% - 10%
|
|
x
|
x
|
|
|
|
|
|
Endocrine disorder
|
Endocrine disorder
|
|
|
|
|
|
|
|
|
x
|
Epistaxis
|
Epistaxis
|
|
|
|
|
|
|
|
|
x
|
Eructation
|
Eructation
|
|
|
|
|
|
|
|
|
x
|
Excoriation
|
Excoriation
|
|
|
|
x
|
|
|
|
|
|
Fasting
|
Fasting
|
|
|
|
|
x
|
|
|
|
|
Fatigue
|
Fatigue
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Furuncle
|
Furunculosis
|
|
|
|
|
|
|
|
|
x
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
|
|
|
|
|
|
|
|
x
|
Cardiac disorder
|
Cardiac disorder
|
|
|
|
|
|
|
|
|
x
|
Cardiac failure congestive
|
Cardiac failure congestive
|
|
|
|
|
|
|
|
|
x
|
Subdural haematoma
|
Subdural haematoma
|
|
|
|
|
|
x
|
x
|
x
|
x
|
Herpes zoster
|
Herpes zoster
|
|
|
|
|
|
|
|
|
x
|
Hyperbilirubinaemia
|
Hyperbilirubinaemia
|
0% - 3.77%
|
|
|
|
x
|
x
|
x
|
x
|
|
Hypercalcaemia
|
Hypercalcaemia
|
|
|
|
|
|
|
|
|
x
|
Hyperglycaemia
|
Hyperglycaemia
|
0% - 5.7%
|
|
|
|
x
|
x
|
x
|
x
|
|
Hyperkalaemia
|
Hyperkalaemia
|
0% - 1.9%
|
|
|
|
|
x
|
x
|
x
|
|
Hypernatraemia
|
Hypernatraemia
|
0% - 1.2%
|
|
|
|
|
x
|
x
|
x
|
|
Hypertriglyceridaemia
|
Hypertriglyceridaemia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Blood triglycerides increased
|
Hypertriglyceridaemia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
Hypocalcaemia
|
Hypocalcaemia
|
0% - 1.2%
|
|
|
|
|
x
|
x
|
x
|
|
Hypokalaemia
|
Hypokalaemia
|
|
|
|
|
|
|
|
|
x
|
Hyponatraemia
|
Hyponatraemia
|
0% - 9.4%
|
|
|
|
|
x
|
x
|
x
|
x
|
Jaundice
|
Jaundice
|
|
|
|
|
|
|
|
|
x
|
Jaundice cholestatic
|
Jaundice cholestatic
|
|
|
|
|
|
|
|
|
x
|
Lacrimal disorder
|
Lacrimal disorder
|
|
|
|
|
|
|
|
|
x
|
Lacrimal structural disorder
|
Lacrimal disorder
|
|
|
|
|
|
|
|
|
x
|
Laryngospasm
|
Laryngospasm
|
|
|
|
|
|
|
|
|
x
|
Muscle spasms
|
Cramps of lower extremities
|
|
|
|
|
|
|
|
|
x
|
Muscle spasms
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Lethargy
|
Lethargy
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Lung disorder
|
Lung disorder
|
|
|
|
|
|
|
|
|
x
|
Hypertonia
|
Hypertonia
|
|
|
|
|
|
|
|
|
x
|
Nervous system disorder
|
Nervous system disorder
|
|
|
|
|
|
|
|
|
x
|
Nervousness
|
Nervousness
|
|
|
|
|
|
|
|
|
x
|
Tension
|
Nervousness
|
|
|
|
|
|
|
|
|
x
|
Neuritis
|
Neuritis
|
|
|
|
|
|
|
|
|
x
|
Neutropenia
|
Neutropenia
|
|
|
|
|
x
|
x
|
x
|
x
|
|
Night blindness
|
Night blindness
|
|
|
|
|
|
|
|
|
x
|
Nocturia
|
Nocturia
|
|
|
|
|
|
|
|
|
x
|
Nystagmus
|
Nystagmus
|
|
|
|
|
|
|
|
|
x
|
Pallor
|
Pallor
|
|
|
|
|
|
|
|
|
x
|
Palpitations
|
Palpitations
|
|
|
|
|
|
|
|
|
x
|
Pancreatitis
|
Pancreatitis
|
0% - 5.66%
|
|
|
|
x
|
x
|
x
|
x
|
|
Pelvic pain
|
Pelvic pain
|
|
|
|
|
|
|
|
|
x
|
Petechiae
|
Petechiae
|
|
|
|
|
|
|
|
|
x
|
Pleural disorder
|
Pleural disorder
|
|
|
|
|
|
|
|
|
x
|
Polyuria
|
Polyuria
|
|
|
|
|
|
|
|
|
x
|
Urine output increased
|
Polyuria
|
|
|
|
|
|
|
|
|
x
|
Psoriasis
|
Psoriasis
|
|
|
|
|
|
|
|
|
x
|
Seborrhoeic dermatitis
|
Seborrhoeic dermatitis
|
|
|
|
|
|
|
|
|
x
|
Sinusitis
|
Sinusitis
|
|
|
|
|
|
|
|
|
x
|
Stomatitis
|
Stomatitis
|
|
|
|
|
|
|
|
|
x
|
Mouth ulceration
|
|
|
|
|
|
|
|
|
x
|
Thirst
|
Thirst
|
|
|
|
|
|
|
|
|
x
|
Tinnitus
|
Tinnitus
|
|
|
|
|
|
|
|
|
x
|
Erythema
|
Erythema
|
|
|
|
x
|
|
|
|
|
|
Redness
|
|
|
|
x
|
|
|
|
|
|
Urethral disorder
|
Urinary tract disorder
|
|
|
|
|
|
|
|
|
x
|
Urinary tract disorder
|
Urinary tract disorder
|
|
|
|
|
|
|
|
|
x
|
Angiopathy
|
Angiopathy
|
|
|
|
|
|
|
|
|
x
|
Viral infection
|
Viral infection
|
|
|
|
|
|
|
|
|
x
|
Urinary retention
|
Urinary retention
|
|
|
|
|
|
|
|
|
x
|
Peripheral vascular disorder
|
Peripheral vascular disorder
|
|
|
|
|
|
|
|
|
x
|
Skin odour abnormal
|
Body odor
|
|
|
|
|
|
|
|
|
x
|
Stupor
|
Stupor
|
|
|
|
|
|
|
|
|
x
|
Depressed level of consciousness
|
Stupor
|
|
|
|
|
|
|
|
|
x
|
Mood swings
|
Mood swings
|
|
|
|
|
|
|
|
|
x
|
Affect lability
|
Mood swings
|
|
|
|
|
|
|
|
|
x
|
Mouth ulceration
|
Mouth ulceration
|
|
|
|
|
|
|
|
|
x
|
Migraine
|
Migraine
|
|
|
|
|
|
|
|
|
x
|
Amylase increased
|
Amylase increased
|
|
|
|
|
|
x
|
x
|
x
|
x
|
Generalised oedema
|
Generalised oedema
|
|
|
|
|
|
|
|
|
x
|
Fluid retention
|
Generalised oedema
|
|
|
|
|
|
|
|
|
x
|
Hypocholesterolaemia
|
Hypocholesterolaemia
|
|
|
|
|
|
|
|
|
x
|
Hypomagnesaemia
|
Hypomagnesaemia
|
|
|
|
|
|
|
|
|
x
|
Hepatocellular injury
|
Hepatocellular injury
|
|
|
|
|
|
|
|
|
x
|
Liver injury
|
Hepatocellular injury
|
|
|
|
|
|
|
|
|
x
|
Pancytopenia
|
Bone marrow depression
|
|
|
|
|
|
|
|
|
x
|
Eye pain
|
Eye pain
|
|
|
|
|
|
|
|
|
x
|
Paraesthesia oral
|
Circumoral paresthesia
|
|
|
|
|
|
|
|
|
x
|
Blood alkaline phosphatase increased
|
Phosphatase alkaline increased
|
|
|
|
|
|
|
|
|
x
|
Blood thromboplastin decreased
|
Thromboplastin decreased
|
|
|
|
|
|
|
|
|
x
|
White blood cell disorder
|
WBC abnormal NOS
|
0% - 6%
|
|
x
|
x
|
|
|
|
|
x
|
Vascular anomaly
|
Vascular anomaly
|
|
|
|
|
|
|
|
|
x
|
Abnormal faeces
|
Abnormal faeces
|
|
|
|
|
|
|
|
|
x
|
Photosensitivity reaction
|
Photosensitivity reaction
|
|
|
|
|
|
|
|
|
x
|
Lichenoid keratosis
|
Eruption lichenoid
|
|
|
|
|
|
|
|
|
x
|
Malaise
|
Malaise
|
|
|
|
|
|
|
|
|
x
|
Discomfort
|
Malaise
|
|
|
|
|
|
|
|
|
x
|
Ill-defined disorder
|
Malaise
|
|
|
|
|
|
|
|
|
x
|
Increased appetite
|
Increased appetite
|
|
|
|
|
|
|
|
|
x
|
Proctalgia
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
x
|
Rectal tenesmus
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
x
|
Anorectal discomfort
|
Rectal tenesmus
|
|
|
|
|
|
|
|
|
x
|
Thinking abnormal
|
Thinking abnormal
|
|
|
|
|
|
|
|
|
x
|
Mental disability
|
Thinking abnormal
|
|
|
|
|
|
|
|
|
x
|
Urine abnormality
|
Urine abnormality
|
|
|
|
|
|
|
|
|
x
|
Urine analysis abnormal
|
Urine abnormality
|
|
|
|
|
|
|
|
|
x
|
Dermatitis bullous
|
Rash bullous
|
|
|
|
|
|
x
|
x
|
x
|
|
Erectile dysfunction
|
Erectile dysfunction
|
|
|
|
|
|
|
|
|
x
|
Hypolipidaemia
|
Hypolipidaemia
|
|
|
|
|
|
|
|
|
x
|
Abdominal distension
|
Enlargement abdomen
|
|
|
|
|
|
|
|
|
x
|
Rash maculo-papular
|
Rash maculo-papular
|
0% - 6%
|
|
x
|
x
|
|
|
|
|
x
|
Face oedema
|
Face oedema
|
|
|
|
|
|
|
|
|
x
|
Hypovolaemia
|
Hypovolaemia
|
|
|
|
|
|
|
|
|
x
|
Lipase increased
|
Lipase increased
|
|
|
|
|
|
|
|
|
x
|
Gait disturbance
|
Gait disturbance
|
|
|
|
|
|
|
|
|
x
|
Blood uric acid increased
|
Hyperuricaemia
|
|
|
|
|
|
|
|
|
x
|
Hyperuricaemia
|
Hyperuricaemia
|
|
|
|
|
|
|
|
|
x
|
Febrile neutropenia
|
Febrile neutropenia
|
|
|
|
|
x
|
|
|
|
|
Rash papular
|
Rash papular
|
|
|
|
|
|
x
|
x
|
x
|
|
Breast enlargement
|
Breast enlargement
|
|
|
|
|
|
|
|
|
x
|
Somnolence
|
Somnolence
|
|
|
|
|
|
|
|
|
x
|