Nicotine

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.)

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Headache def Headache def 18% 15% x x
Back pain def Back pain def 6% 4% x
Pain def Pain def 3% - 6% 3% - 4% x x
Arthralgia def Arthralgia def 5% 1% x
Musculoskeletal discomfort Arthralgia def 5% 1% x
Myalgia def 3% 4% x x
Dyspnoea def Dyspnoea def 5% 6% x
Nausea def Nausea def 5% 5% x x
Flatulence def Flatulence def 4% 3% x x
Menstrual disorder def Menstrual disorder def 4% 4% x
Palpitations def Palpitations def 4% 4% x
Tooth disorder def Tooth disorder def 4% 1% x x
Abdominal pain def Abdominal pain def 3% 3% x
Gastrointestinal pain def Abdominal pain def 3% 3% x
Confusional state def Confusional state def 3% 3% x
Feeling abnormal Confusional state def 3% 3% x
Dysmenorrhoea def Dysmenorrhoea def 3% 0% x
Myalgia def Myalgia def 3% 4% x x
Acne def Acne def 3% 1% x
Pruritus def Pruritus def 2% 3% x
Amnesia def Amnesia def x
Anxiety def Anxiety def x x
Aphasia def Aphasia def x
Blister def Blister def x
Dermatitis bullous def Blister def x
Bronchospasm def Bronchospasm def x
Bronchitis def Bronchitis def x x
Constipation def Constipation def x
Cough def Cough def x x
Diarrhoea def Diarrhoea def x x
Dizziness def Dizziness def x x
Drug abuse def Drug abuse def x
Dyspepsia def Dyspepsia def x x
Ear pain def Ear pain def x
Oedema def Oedema def x
Epistaxis def Epistaxis def x
Dermatitis def Rash def x
Rash def Rash def x
Asthenia def Fatigue def x x
Fatigue def Fatigue def x x
Body temperature increased def Body temperature increased def x
Flushing def Flushing def x
Hiccups def Hiccups def x x
Dysphonia def Hoarseness def x
Hypersensitivity def Hypersensitivity def x x
Hypertension def Hypertension def x
Influenza def Influenza def x
Irritability def Irritability def x
Nasal congestion def Nasal congestion def x
Hypoaesthesia def Numbness def x
Sensory loss Numbness def x
Paraesthesia def Paraesthesia def x x
Tingling sensation def x
Pharyngitis def Pharyngitis def x
Purpura def Purpura def x
Vascular purpura Purpura def x
Rhinitis def Rhinitis def x
Sinusitis def Sinusitis def x
Sneezing def Sneezing def x
Stomatitis def Stomatitis def x
Withdrawal syndrome def Withdrawal syndrome def x
Hyperhidrosis def Sweating def x
Sweating increased x
Tremor def Tremor def x
Ulcer def Ulcer def x
Visual impairment def Visual impairment def x
Visual acuity reduced Visual impairment def x
Blindness def Visual impairment def x
Weight increased def Weight increased def x
Dry mouth def Dry mouth def x
Agitation def Agitation def x
Apathy def Apathy def x
Flat affect Apathy def x
Mood swings Mood swings x
Affect lability Mood swings x
Oedema peripheral def Oedema peripheral def x
Migraine def Migraine def x
Lacrimation increased def Lacrimation increased def x
Malaise def Sickness x
Chest discomfort Chest tightness x
Chest discomfort x
Increased appetite Increased appetite x
Discomfort def Discomfort def x
Disturbance in attention Cerebration impaired def x
Mental disability Cerebration impaired def x
Eye irritation Eye irritation x
Sputum increased Sputum increased x
Increased bronchial secretion Sputum increased x
Chest pain def Chest discomfort x
Pain in jaw Pain in jaw x
Nasal discomfort Nasal irritation x
Nasal ulcer Nasal ulcer x
Tobacco user Smoker def x x
Dependence def Dependence def x
Coordination abnormal Coordination abnormal x
Throat irritation Throat irritation x x
Sleep disorder def Sleep disorder def x
Insomnia def Insomnia def x
Nasopharyngitis def Rhinorrhoea def x
Rhinorrhoea def Rhinorrhoea def x
Drug dependence def Drug dependence def x
Somnolence def Somnolence def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N07BA01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. nicotine : 29 side effects (FDA XML label)
  2. nicotine : 74 side effects (FDA XML label)