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Zidovudine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: J05AF01, S01AD05

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 26 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Headache Headache very common, 8.5% - 63% 37% - 53% x x x x x x x x x x x x x x x x x x x x
Malaise Malaise common, 8% - 55.6% 7% - 45% x x x x x x x x x x x x x x x x x x x x
Sickness x x x x x
Discomfort Malaise common, 8% - 55.6% 7% - 45% x x x x x x x x x x x x x x x x x x x x
Feeling abnormal Malaise common, 8% - 55.6% 7% - 45% x x x x x x x x x x x x x x x x x x x x
Confusional state postmarketing x x x x x x x x x x x x x x x x x x
Ill-defined disorder Malaise common, 8% - 55.6% 7% - 45% x x x x x x x x x x x x x x x x x x x x
Nausea Nausea rare — 7% - 61% 18% - 41% x x x x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased uncommon, 2.13% - 32% 12% x x x x x x x x x x x x x x x x x x x x
Decreased appetite Anorexia rare, 6.38% - 20.1% 8% - 11% x x x x x x x x x x x x x x x x x x x x
Gastrointestinal pain Gastrointestinal pain 20% 19% x x x x x
Abdominal pain common, 8.51% - 21.3% x x x x x x x x x x x x x x x x x x x x
Cough Cough rare, 15% - 18% x x x x x x x x x x x x x x x x x x x x
Vomiting Vomiting common, 2.13% - 25% 3% - 13% x x x x x x x x x x x x x x x x x x x x
Dermatitis Rash postmarketing — 12% - 17% 15% x x x x x x x x x x x x x x x x x x x x
Rash Rash postmarketing — 12% - 17% 15% x x x x x x x x x x x x x x x x x x x x
Stomatitis Stomatitis 6% - 12% x x x x x x x x x x x x x
Mouth ulceration postmarketing, 4.26% - 27.7% x x x x x x x x x x x x x x x x x x
Hepatomegaly Hepatomegaly postmarketing — 11% x x x x x x x x x x x x x x x x x x x x
Nasopharyngitis Rhinorrhoea 8% - 11% x x x x x x x x x x x x x
Rhinorrhoea Rhinorrhoea 8% - 11% x x x x x x x x x x x x x
Asthenia Asthenia uncommon, 8.6% - 9% 5.8% - 6% x x x x x x x x x x x x x x x x x x x x
Fatigue x x x x x x x x x x x x x x x x
Wheezing Wheezing 7% - 9% x x x x x x x x x x x x x
Breath sounds abnormal Breath sounds abnormal 7% - 9% x x x x x x x x x x x x x
Lymphadenopathy Lymphadenopathy postmarketing, 9% - 11% x x x x x x x x x x x x x x x x x x
Splenomegaly Splenomegaly 5% - 8% x x x x x x x x x x x x x
Myalgia Myalgia common, 8% 2% x x x x x x x x x x x x x x x x x x x x
Musculoskeletal discomfort Myalgia common, 8% 2% x x x x x x x x x x x x x x x x x x x x
Arthralgia x x x x x x x x x x x x x x x x x x
Abdominal pain Abdominal pain common, 8.51% - 21.3% x x x x x x x x x x x x x x x x x x x x
Abdominal cramps x x x x x x x x x x x x x
Constipation Constipation 6% - 8.1% 3.5% - 4% x x x x x x x x x x x x x x x x x x
Diarrhoea Diarrhoea common, 6% - 14.9% 18% x x x x x x x x x x x x x x x x x x x x
Weight decreased Weight decreased 4.26% - 6.38% x x x x x x x x x x x x x x x x x x
Chills Rigors 2.13% - 8.51% x x
Chills rare x x x x x x x x x x x x x x x x x x x x
Dyspepsia Dyspepsia rare, 5% - 6% 1% - 4% x x x x x x x x x x x x x x x x x x x x
Hyperhidrosis Sweating increased 5% 4% x x x x x
Sweating rare x x x x
Hyperlactacidaemia Hyperlactacidaemia common x x x x
Insomnia Insomnia rare, 5% 1% x x x x x x x x x x x x x x x x x x x x
Neuropathy peripheral Neuropathy peripheral 4% - 25.5% x x x
Neuropathy x x x x x x x x x x x x x
Neutropenia Neutropenia common, 3% x x x x x x x x x x x x x x x x x x x x
Pharyngitis Pharyngitis 2.1% - 8.51% x x x x x
Agranulocytosis Agranulocytosis 1.8% - 2% 1.6% - 2% x x x x x x x x x x x x x x x x x
Anaemia Anaemia common, 1% - 2% 0.2% - 1% x x x x x x x x x x x x x x x x x x x x
Pain Pain uncommon x x x x x x x
Generalized aching postmarketing x x x x x x x x x x x x x
Thrombocytopenia Thrombocytopenia uncommon, 0% - 3% 0.5% - 1% x x x x x x x x x x x x x x x x x x x x
Lactic acidosis Lactic acidosis postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Amblyopia Amblyopia postmarketing x x x x x x x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x x x x x x x x x x x
Aplastic anaemia Aplastic anaemia very rare, postmarketing x x x x x x x x x x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia postmarketing x x x x x x x x x x x x x
Angioedema Angioedema postmarketing x x x x x x x x x x x x x
Anxiety Anxiety postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Back pain Back pain postmarketing x x x x x x x x x x x x x x x x x x
Chest pain Chest pain postmarketing — 2.13% - 6.38% x x x x x x x x x x x x x x x x x x x x
Confusional state Confusional state postmarketing x x x x x x x x x x x x x x x x x x
Dysphagia Dysphagia postmarketing x x x x x x x x x x x x x x x x x x
Dizziness Dizziness postmarketing — 6% - 20.8% 4% - 15.2% x x x x x x x x x x x x x x x x x x x x
Syncope postmarketing x x x x x x x x x x x x x x x x x x
Dysgeusia Dysgeusia postmarketing — 5% 8% x x x x x x x x x x x x x x x x x x x x
Dyspnoea Dyspnoea postmarketing — 5% 3% x x x x x x x x x x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis postmarketing x x x x x x x x x x x x
Flatulence Flatulence postmarketing, uncommon x x x x x x x x x x x x x x x x x x x x
Gynaecomastia Gynaecomastia postmarketing, rare x x x x x x x x x x x x x x x x
Hepatitis Hepatitis postmarketing x x x x x x x x x x x x x x x x x
Influenza Influenza rare x x x x x x x
Jaundice Jaundice postmarketing x x x x x x x x x x x x x
Leukopenia Leukopenia postmarketing, common x x x x x x x x x x x x x x x x x x
Liver disorder Liver disorder rare x x x
Hepatocellular injury Liver disorder rare x x x
Foetor hepaticus Liver disorder rare x x x
Myopathy Myopathy postmarketing, uncommon x x x x x x x x x x x x x x x x x x x x
Myositis Myositis postmarketing x x x x x x x x x x x x x x x x x
Pancreatitis Pancreatitis postmarketing x x x x x x x x x x x x x x x x x x x x
Pancytopenia Pancytopenia postmarketing, uncommon x x x x x x x x x x x x x x x x x x
Bone marrow depression postmarketing, uncommon x x x x x x x x x x x x x x x x x x
Paraesthesia Paraesthesia postmarketing — 6% 3% x x x x x x x x x x x x x x x x x x x x
Pruritus Pruritus postmarketing, uncommon x x x x x x x x x x x x x x x x x x x x
Aplasia pure red cell Aplasia pure red cell postmarketing, rare x x x x x x x x x x x x x x x
Red cell aplasia x
Rhabdomyolysis Rhabdomyolysis postmarketing x x x x x x x x x x x x x
Rhinitis Rhinitis postmarketing x x x x x x x x x x x x x x x x x x
Convulsion Convulsion postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Sinusitis Sinusitis postmarketing x x x x x x x x x x x x x x x x x x
Pigmentation disorder Pigmentation skin rare x x
Muscle spasms Muscle spasms postmarketing x x x x x x x x x x x x x x x x x x
Erythema multiforme Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x
Shock Syncope postmarketing x x x x x x x x x x x x x x x x x x
Syncope Syncope postmarketing x x x x x x x x x x x x x x x x x x
Loss of consciousness Syncope postmarketing x x x x x x x x x x x x x x x x x x
Tremor Tremor postmarketing x x x x x x x x x x x x x x x x x x
Pollakiuria Pollakiuria postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Urticaria Urticaria postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Vasculitis Vasculitis postmarketing x x x x x x x x x x x x x x x x x
Vertigo Vertigo postmarketing x x x x x x x x x x x x x x x x x x
Photophobia Photophobia postmarketing x x x x x x x x x x x x x x x x x x
Mouth ulceration Mouth ulceration postmarketing, 4.26% - 27.7% x x x x x x x x x x x x x x x x x x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased postmarketing x x x x x x x x x x x x x
Urinary hesitation Urinary hesitation postmarketing x x x x x x x x x x x x x x x x x x
Macular oedema Macular oedema postmarketing x x x x x x x x x x x x x x x x x
Mania Mania postmarketing x x x x x x x x x x x x x
Cardiomyopathy Cardiomyopathy postmarketing, rare x x x x x x x x x x x x x x x x x x x x
Nail pigmentation Nail pigmentation postmarketing x x x x x x x x x x x x x x x x x x
Sensitisation Sensitisation postmarketing x x x x x x x x x x x x x x x x x x
Deafness Hearing impaired postmarketing x x x x x x x x x x x x x x x x x x
Hearing impaired Hearing impaired postmarketing x x x x x x x x x x x x x x x x x x
Mucosal pigmentation Mucosal pigmentation postmarketing, rare x x x x x x x x x x x x x x x x x
Somnolence Somnolence postmarketing — 8% 9% x x x x x x x x x x x x x x x x x x x x
Congenital anomaly Congenital anomaly x
Developmental delay Congenital anomaly x
Acidosis Acidosis x
Acquired immunodeficiency syndrome Acquired immunodeficiency syndrome x x
Autoimmune disorder Acquired immunodeficiency syndrome x x
Arthralgia Arthralgia x x x x x x x x x x x x x x x x x x
Bacteraemia Bacteraemia x x x x
Mental disorder Mental disorder x x
Breast disorder Breast disorder x x
Connective tissue disorder Connective tissue disorder x x
Cystitis Cystitis x x x x
Bladder pain Cystitis x x x x
Cystitis noninfective Cystitis x x x x
Dysuria Dysuria x x x x x
Oedema Oedema x x x x x x x x x x x x x x x x x x
Epistaxis Epistaxis x x x x x
Eructation Eructation x x x x x
Fatigue Fatigue x x x x x x x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x x
Gingival bleeding Gingival bleeding x x x x x
Cardiac disorder Cardiac disorder x x
Cardiac failure congestive Cardiac failure congestive x x x x x x x x x x x x x x x x x
Haematuria Haematuria x x x x x x x x x x x x x x x x x
Hepatitis C Hepatitis C x x x x x x x x x x
Dysphonia Hoarseness x x x x x
Hyperpathia Hyperpathia x x x x x
Hyperaesthesia Hyperpathia x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia x x x x x x x x x x x x x x x x x
Irritability Irritability x x x x x x x x x x x x x x x x x
Mediastinal disorder Mediastinal disorder x x
Musculoskeletal pain Musculoskeletal pain x x x x x x x x x x x x x
Nervous system disorder Nervous system disorder x x
Nervousness Nervousness x x x x x x x x x x x x x x x x x x
Tension Nervousness x x x x x x x x x x x x x x x x x x
Night sweats Night sweats x x x
Phlebitis Phlebitis x x x x
Polyuria Polyuria x x x x x
Urine output increased Polyuria x x x x x
Erythema Erythema x x x x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Vasodilation procedure Vasodilation x x x x x
Skin odour abnormal Body odor x x x x x
Mood swings Mood swings x x x x x
Affect lability Mood swings x x x x x
Generalised oedema Generalised oedema x x x x
Fluid retention Generalised oedema x x x x
Tongue disorder Tongue oedema x x x
Tongue oedema Tongue oedema x x x
Hyporeflexia Hyporeflexia x x x x x x x x x x x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Skin discolouration Skin discolouration x
Malnutrition Malnutrition x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x
Muscle twitching Muscle twitching x x x x x
Rash erythematous Rash erythematous x x x
Rash follicular Rash follicular x x x
Swollen tongue Swollen tongue x x x
Localised oedema Oedema auricular x x x x
Rectal haemorrhage Rectal haemorrhage x x x x x
Hepatobiliary disease Hepatobiliary disease x
Rash maculo-papular Rash maculo-papular x x x
Auricular swelling Auricular swelling x x x x
Drug interaction Drug interaction x
Hypoxia Hypoxemia x
Acne Acne x x x
Local reaction Local reaction x x x
Fat redistribution Fat redistribution x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

ZIDOVUDINE / RETROVIR

Side effects:93
Source:FDA

Zidovudine

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

Zidovudine

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE

Side effects:94
Source:FDA Structured Product Label

ZIDOVUDINE / RETROVIR

Side effects:94
Source:FDA

ZIDOVUDINE / RETROVIR

Side effects:94
Source:FDA

zidovudine / RETROVIR

Side effects:97
Source:FDA

zidovudine / RETROVIR

Side effects:97
Source:FDA

ZIDOVUDINE

Side effects:98
Source:FDA Structured Product Label

ZIDOVUDINE / APO ZIDOVUDINE CAP 100MG

Side effects:107
Source:Health Canada

ZIDOVUDINE / RETROVIR (AZT)

Side effects:108
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label