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Thiotepa

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01AC01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Chemical cystitis Chemical cystitis 1-69% x
Alopecia Alopecia 1-10% x x
Amenorrhoea Amenorrhoea 1-10% x x
Decreased appetite Anorexia 1-10% x x
Decreased appetite x
Asthenia Asthenia 1-10% x x
Fatigue 1-10% x
Conjunctivitis Conjunctivitis 1-10% x x
Dizziness Dizziness 1-10% x x
Dermatitis Rash 1-10% x x
Dermatitis x
Rash Rash 1-10% x x
Fatigue Fatigue 1-10% x
Body temperature increased Body temperature increased 1-10% x x
Headache Headache 1-10% x x
Hypersensitivity Hypersensitivity 1-10% x x
Pruritus Pruritus 1-10% x x
Urticaria Urticaria 1-10% x
Vomiting Vomiting 1-10% x x
Urinary retention Urinary retention 1-10% x
Skin hyperpigmentation Skin hyperpigmentation 1-10% x
Acute myeloid leukaemia Acute myeloid leukaemia 1% x
Acute leukaemia Acute myeloid leukaemia 1% x
Myeloid leukaemia x
Abdominal pain Abdominal pain x x
Gastrointestinal pain Abdominal pain x x
Agranulocytosis Agranulocytosis x
Anaemia Anaemia x x
Anxiety Anxiety x
Arrhythmia Arrhythmia x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Myalgia x
Ataxia Ataxia x
Azoospermia Azoospermia x x
Back pain Back pain x
Mental disorder Mental disorder x
Bladder disorder Bladder disorder x
Neoplasm malignant Neoplasm malignant x
Intracranial aneurysm Intracranial aneurysm x
Cognitive disorder Cognitive disorder x
Colitis Colitis x
Infection Infection x x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Connective tissue disorder Connective tissue disorder x
Constipation Constipation x
Cough Cough x
Cystitis Cystitis x
Bladder pain Cystitis x
Cystitis noninfective Cystitis x
Cyst Cyst x
Pancytopenia Cytopenia x
Pancytopenia x
Myelosuppression x
Dehydration Dehydration x
Delirium Delirium x
Dermatitis contact Dermatitis contact x
Diarrhoea Diarrhoea x
Dyspepsia Dyspepsia x
Dysuria Dysuria x x
Embolism Embolism x
Endocrine disorder Endocrine disorder x
Enteritis Enteritis x
Epistaxis Epistaxis x
Oesophagitis Oesophagitis x
Extrapyramidal disorder Extrapyramidal disorder x
Extravasation Extravasation x
Eye disorder Eye disorder x
Gastrointestinal disorder Gastrointestinal disorder x
Graft versus host disease Graft versus host disease x
Hallucination Hallucination x
Cardiac arrest Cardiac arrest x
Cardiac disorder Cardiac disorder x
Cardiac failure Cardiac failure x
Haematuria Haematuria x
Haemorrhage Haemorrhage x x
Haemoglobin Haemorrhage x x
Venoocclusive liver disease Venoocclusive liver disease x
Hepatomegaly Hepatomegaly x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hyperglycaemia Hyperglycaemia x
Hypertension Hypertension x
Hypogonadism Hypogonadism x
Hypopituitarism Hypopituitarism x
Hypothyroidism Hypothyroidism x
Immune system disorder Immune system disorder x
Infertility female Infertility female x
Infertility male Infertility male x
Intestinal obstruction Intestinal obstruction x
Jaundice Jaundice x
Myeloid leukaemia Myeloid leukaemia x
Leukopenia Leukopenia x x
Lymphoedema Lymphoedema x
Mediastinal disorder Mediastinal disorder x
Meningism Meningism x
Menopause Menopause x
Multi-organ failure Multi-organ failure x
Myelodysplastic syndrome Myelodysplastic syndrome x
Myocarditis Myocarditis x
Nausea Nausea x x
Nervous system disorder Nervous system disorder x
Nervousness Nervousness x
Tension Nervousness x
Oliguria Oliguria x
Pain Pain x x
Paresis Paresis x
Paraesthesia Paraesthesia x
Pneumonia Pneumonia x
Polyp Polyp x
Pulmonary oedema Pulmonary oedema x
Renal failure Renal failure x
Convulsion Convulsion x
Sepsis Septicemia x
Sepsis x
Stomatitis Stomatitis x x
Tachycardia Tachycardia x
Thrombocytopenia Thrombocytopenia x x
Tinnitus Tinnitus x
Erythema Erythema x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x
Weight increased Weight increased x
Encephalopathy Encephalopathy x
Chills Chills x
Hepatic failure Hepatic failure x
Agitation Agitation x
Photophobia Photophobia x
Cystitis haemorrhagic Cystitis haemorrhagic x x
Cataract Cataract x
Blood urea increased Blood urea increased x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Gastrointestinal perforation Gastrointestinal perforation x
Growth retardation Growth retardation x
Injection site inflammation Injection site inflammation x
Injection site pain Injection site pain x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Respiratory arrest Respiratory arrest x
Malnutrition Malnutrition x
Leukoderma Leukoderma x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Myalgia Myalgia x
Memory impairment Memory impairment x
Ototoxicity Ototoxicity x
Blood creatinine increased Blood creatinine increased x
Infection susceptibility increased Infection susceptibility increased x
Skin exfoliation Skin exfoliation x
Gastrointestinal ulcer Gastrointestinal ulcer x
Hypoxia Hypoxia x
Hepatobiliary disease Hepatobiliary disease x
Blood bilirubin increased Blood bilirubin increased x
Mucosal inflammation Mucosal inflammation x x
Vision blurred Vision blurred x x
Meningitis chemical Meningitis chemical x
Transaminases increased Transaminases increased x
Transaminitis x
Skin discolouration Pigmentation disorder x
Pigmentation disorder Pigmentation disorder x
Toxic shock syndrome Toxic shock syndrome x
Blood uric acid increased Hyperuricaemia x
Hyperuricaemia Hyperuricaemia x
Eosinophilic cystitis Eosinophilic cystitis x
Febrile neutropenia Febrile neutropenia x x
Erythrodermic psoriasis Erythrodermic psoriasis x
Infestation Infestation NOS x
Blood alkaline phosphatase increased Blood alkaline phosphatase increased x
Amylase increased Blood amylase increased x
Blood electrolytes abnormal Blood electrolytes abnormal x
Mental status changes Mental status changes x
Acute graft versus host disease Acute graft versus host disease x
Thrombocytopenic purpura Thrombocytopenic purpura x
Chronic graft versus host disease Chronic graft versus host disease x
Cardiomyopathy Cardiomyopathy x
Ileus Ileus x
Deafness Hearing impaired x
Hearing impaired Hearing impaired x
Cardiovascular insufficiency Cardiovascular insufficiency x
Idiopathic pneumonia syndrome Idiopathic pneumonia syndrome x
Somnolence Somnolence x
Cerebral haemorrhage Cerebral haemorrhage x
Vaginal haemorrhage Vaginal haemorrhage x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Thiotepa

Side effects:52
Source:BC Cancer

thiotepa / thiotepa

Side effects:147
Source:EMA

Color scheme:

standard – alternative

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    infrequent (0.1% to 1%)
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    postmarketing
    0%
    no frequency information
    not found on label