Definition: A rare acute life-threatening systemic bacterial noncontagious illness caused by any of several related staphylococcal exotoxins. TSS characterized by high fever, hypotension, rash, multi-organ dysfunction, and cutaneous desquamation during the early convalescent period. The toxins affect the host immune system, causing an exuberant and pathological host inflammatory response. Laboratory findings consistent with TSS include leukocytosis, elevated prothrombin time, hypoalbuminemia, hypocalcemia, and pyuria.
Synonyms (terms occurring on more labels are shown first): toxic shock syndrome, toxic shock
Drugs with this side effect as MedDRA Preferred Term