Testosterone

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 27)
1 2 3 4 5 6 7 8 9 10
Pruritus def Pruritus def postmarketing, 1.9% - 37% x x x x x x
Blister def Blister def postmarketing, 12% x x x x
Dermatitis bullous def Blister def postmarketing, 12% x x x x
Rash bullous postmarketing x
Prostatic disorder def Prostatic disorder def postmarketing, 1.2% - 11.7% x x x x x x
Prostatomegaly Enlarged prostate postmarketing, 11.7% x x
Prostatic specific antigen increased Prostatic specific antigen increased 1% - 11.1% 0% x x x
Laboratory test abnormal Laboratory test abnormal postmarketing, 3% - 9.3% x
Stomatitis def Mouth irritation 9.2% x
Stomatitis def x
Buccal inflammation x
Acne def Acne def postmarketing, 1% - 8% x x x x x x x x x
Erythema def Erythema def postmarketing, 5% - 7% x x x x x x
Redness def x
Haematocrit increased Haematocrit increased 4% - 7% x x x x
Back pain def Back pain def 6% x
Headache def Headache def postmarketing, 0% - 6% 0% x x x x x x x x x x
Pain def Pain def postmarketing, 1% - 6% x x x x x
Stinging x
Application site reaction Application site reaction 3% - 5.6% x x
Dysgeusia def Taste bitter 4.1% x
Dysgeusia def 2% x
Dermatitis def Dermatitis def postmarketing, 2.14% - 4% 0% x x x x x
Rash def postmarketing, 2% x x x x x
Dermatitis contact def Dermatitis contact def 2.14% - 4% 0% x x x x
Allergic contact dermatitis def x
Diarrhoea def Diarrhoea def postmarketing, 3% - 4% x x x x
Vomiting def Vomiting def postmarketing, 3% - 4% x x
Tenderness def Tenderness def postmarketing, 3.1% x x x
Gingival pain def Gingival pain def 3.1% x
Irritation gum x
Asthenia def Asthenia def 0% - 3% x x
Fatigue def postmarketing x x x x x x
Libido decreased def Libido decreased def postmarketing, 0% - 3% x x x x x
Disturbance in sexual arousal Libido decreased def postmarketing, 0% - 3% x x x x x
Libido increased def
Gynaecomastia def Gynaecomastia def postmarketing, 0% - 3% 0% x x x x x
Hypertension def Hypertension def postmarketing, 0% - 3% 0% x x x x x x x x
Hypertension worsened
Breast pain def Breast pain def postmarketing, 1% - 3% x x x
Nervousness def Nervousness def 0% - 3% x
Tension def Nervousness def 0% - 3% x
Mood swings Mood swings 0% - 3% 0% x x x x
Mood alteration NOS def
Affect lability Mood swings 0% - 3% 0% x x x x
Affect lability x
Induration def Induration def postmarketing, 3% x x x
Anaemia def Anaemia def 2.5% x
Haemoglobin increased def Haemoglobin increased def postmarketing, 1% - 2.14% 0% x x
Oedema def Oedema def postmarketing, 2% x x x x
Rash def Rash def postmarketing, 2% x x x x x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def postmarketing, 2% x x x
Haemorrhage def Haemorrhage def postmarketing, 2% x x x
Haemoglobin def Haemorrhage def postmarketing, 2% x x x
Dry skin def Dry skin def 1.9% x x
Abnormal dreams Abnormal dreams 1.3% x
Neoplasm malignant def Carcinoma def postmarketing, 1.2% x x x
Prostate cancer def Prostate carcinoma def postmarketing, 1.2% x x
Prostate cancer def x
Alopecia def Alopecia def postmarketing, 0% - 1% x x x x
Flushing def Flushing def 0% - 1% 0% x x x
Hyperplasia def Hyperplasia def 0% - 1% 1% x x
Lacrimation increased def Lacrimation increased def 0% - 1% 0% x x x
Lacrimation def 0% - 1% 0% x x x
Blood pressure diastolic decreased Blood pressure diastolic decreased 0% - 1% 0%
Blood pressure increased Blood pressure increased 1% 0% x x x x
Menopausal symptoms def Hot flush def 0% - 1% 0% x x x
Hot flush def Hot flush def 0% - 1% 0% x x x
Insomnia def Insomnia def postmarketing, 0% - 1% 0% x x x x
Benign prostatic hyperplasia def Benign prostatic hyperplasia def 0% - 1% 1% x
Prostatic hyperplasia def 0% - 1% 1% x
Benign prostatic hypertrophy def x
Prostatic hypertrophy x
Abdominal pain def Abdominal pain def postmarketing x
Abdominal cramps def x
Gastrointestinal pain def Abdominal pain def postmarketing x
Aggression def Aggression def postmarketing x x x x
Anger def Anger def postmarketing x x x
Anxiety def Anxiety def postmarketing x x x x x x x
Apnoea def Apnoea def postmarketing x x
Arthralgia def Arthralgia def postmarketing x
Musculoskeletal discomfort Arthralgia def postmarketing x
Myalgia def postmarketing x
Mental disorder def Mental disorder def postmarketing x x
Breast disorder def Breast disorder def postmarketing x x x
Confusional state def Confusional state def postmarketing x x x
Feeling abnormal Confusional state def postmarketing x x x
Malaise def postmarketing x x x
Connective tissue disorder def Connective tissue disorder def postmarketing x x
Dizziness def Dizziness def postmarketing x x x
Syncope def x
Dyspnoea def Dyspnoea def postmarketing x x x
Dysuria def Dysuria def postmarketing x x x
Urination impaired postmarketing x
Difficulty in micturition x
Endocrine disorder def Endocrine disorder def postmarketing x x x
Hormone level abnormal Endocrine disorder def postmarketing x x x
Epididymitis def Epididymitis def postmarketing
Fatigue def Fatigue def postmarketing x x x x x x
Gastrointestinal disorder def Gastrointestinal disorder def postmarketing x x x x
Haematuria def Haematuria def postmarketing x x x
Hirsutism def Hirsutism def postmarketing x x x x
Hypercholesterolaemia def Hypercholesterolaemia def postmarketing x x
Hypersensitivity def Hypersensitivity def postmarketing x
Hypertriglyceridaemia def Hypertriglyceridaemia def postmarketing x
Blood triglycerides increased Hypertriglyceridaemia def postmarketing x
Hypertrophy def Hypertrophy def postmarketing x x x x x
Immune system disorder def Immune system disorder def postmarketing x
Incontinence def Incontinence def postmarketing x x x x
Irritability def Irritability def postmarketing x
Nephropathy def Nephropathy def postmarketing
Congenital cystic kidney disease Polycystic kidney def postmarketing
Hepatic neoplasm def Hepatic neoplasm def postmarketing
Mediastinal disorder def Mediastinal disorder def postmarketing x
Nausea def Nausea def postmarketing x x x x x
Nervous system disorder def Nervous system disorder def postmarketing x x x
Nocturia def Nocturia def postmarketing x
Azoospermia def Oligospermia def postmarketing x x x
Peliosis hepatis def Peliosis hepatis def postmarketing x x x
Penis disorder def Penis disorder def postmarketing x x x
Personality disorder def Personality disorder def postmarketing x
Polycythaemia def Polycythaemia def postmarketing x x x x x
Priapism def Priapism def postmarketing x x x
Precocious puberty def Precocious puberty def postmarketing x
Purpura def Purpura def postmarketing x x x
Vascular purpura Purpura def postmarketing x x x
Seborrhoeic dermatitis def Seborrhoeic dermatitis def postmarketing x x
Serum sickness def Serum sickness def postmarketing
Sleep apnoea syndrome def Sleep apnoea syndrome def postmarketing x x
Urinary incontinence def Urinary incontinence def postmarketing x x x
Urethral disorder def Urinary tract disorder def postmarketing x
Urinary tract disorder def Urinary tract disorder def postmarketing x
Urticaria def Urticaria def postmarketing x
Varicocele def Varicocele def postmarketing x
Angiopathy def Angiopathy def postmarketing x x x x
Virilism def Virilism def postmarketing x x x x
Weight increased def Weight increased def postmarketing x x
Urinary retention def Urinary retention def postmarketing x
Urogenital disorder Urogenital disorder postmarketing x
Pollakiuria def Micturition urgency def postmarketing x
Pollakiuria def x
Micturition urgency def Micturition urgency def postmarketing x
Hepatic function abnormal Hepatic function abnormal postmarketing x
Gamma-glutamyltransferase increased def Gamma-glutamyltransferase increased def postmarketing
Growth accelerated def Growth accelerated def postmarketing x x x
Liver function test abnormal Liver function test abnormal postmarketing x x
Aspartate aminotransferase increased def Aspartate aminotransferase increased def postmarketing x
Alanine aminotransferase increased def Alanine aminotransferase increased def postmarketing x
Urinary hesitation Urinary hesitation postmarketing x
Testicular atrophy Testicular atrophy postmarketing x
Androgenetic alopecia Androgenetic alopecia postmarketing x
Malaise def Sickness postmarketing x
Malaise def postmarketing x x x
Discomfort def Malaise def postmarketing x x x
Ill-defined disorder Malaise def postmarketing x x x
Myalgia def Myalgia def postmarketing x
Increased appetite Increased appetite postmarketing x x x x x
Erectile dysfunction def Erectile dysfunction def postmarketing x x x x
Hepatobiliary disease def Hepatobiliary disease def postmarketing x x
Glucose tolerance impaired def Glucose tolerance impaired def postmarketing x x
Atrophy def Atrophy def postmarketing x x
Cognitive disorder def Cognitive impairment def postmarketing x
Surgery def Surgical intervention postmarketing x x x
Blood creatinine increased Serum creatinine increased postmarketing x
Creatinine increased def x x
Aortic dissection def Dissecting aortic aneurysm, thoracic postmarketing x
Hepatic neoplasm malignant Liver carcinoma def postmarketing
Hypertonic bladder def Bladder irritation postmarketing x
Bladder irritation Bladder irritation postmarketing x
Adenoma benign def Adenoma benign def
Amenorrhoea def Amenorrhoea def x
Amnesia def Amnesia def x
Memory loss
Angina pectoris def Angina pectoris def
Appetite disorder Appetite disorder
Asthma def Asthma def x
Convulsion def Convulsion def
Cyst def Cyst def
Dermatitis atopic def Dermatitis atopic def x
Diabetes mellitus def Diabetes mellitus def x
Drug abuse def Drug abuse def
Drug tolerance def Drug habit def
Drug dependence def Drug habit def
Toxic epidermal necrolysis def Toxic epidermal necrolysis def x
Eye disorder def Eye disorder def x
Fasting def Fasting def
Folliculitis def Folliculitis def x
Gastrooesophageal reflux disease def Gastrooesophageal reflux disease def x
Gingivitis def Gingivitis def x
Cardiac disorder def Cardiac disorder def
Haemarthrosis def Haemarthrosis def x
Hepatitis def Hepatitis def
Hostility def Hostility def x
Hyperlipidaemia def Hyperlipidaemia def x
Hypernatraemia def Hypernatraemia def x x
Hypokalaemia def Hypokalaemia def x
Libido increased def Libido increased def
Infection def Infection def x x x x x
Inflammation def Inflammation def x x
Influenza def Influenza def x
Jaundice def Jaundice def x x x
Jaundice cholestatic def Jaundice cholestatic def x x x
Leukopenia def Leukopenia def
Leukoplakia def Leukoplakia def x
Muscle spasms def Cramp muscle def x
Nasopharyngitis def Nasopharyngitis def x
Necrosis def Necrosis def x
Nodule def Nodule def x
Pain in extremity def Pain in extremity def x
Paraesthesia def Paraesthesia def x x x x x
Paresthesia generalized x x x
Pelvic pain def Pelvic pain def x x
Pituitary tumour def Pituitary tumour def x
Pneumonia def Pneumonia def x x
Polyp def Polyp def
Polyuria def Polyuria def x
Urine output increased Polyuria def x
Neoplasm prostate def Neoplasm prostate def x
Prostatitis def Prostatitis def x
Renal failure def Renal failure def
Respiratory disorder def Respiratory disorder def x
Sinusitis def Sinusitis def x
Skin disorder def Skin disorder def
Skin mass Skin nodule def x
Hyperhidrosis def Sweating def x
Swelling def Swelling def x
Shock def Syncope def x
Syncope def Syncope def x
Syncope vasovagal def x
Loss of consciousness def Syncope def x
Thrombosis def Thrombosis def
Toothache def Toothache def x
Ulcer def Ulcer def x x
Urinary tract infection def Urinary tract infection def x x x x
Vasodilation procedure Vasodilation def x
Presyncope def Syncope vasovagal def x
Venous thrombosis def Venous thrombosis def
Vertigo def Vertigo def x x x x
Vitreous detachment def Vitreous detachment def x
Dry mouth def Dry mouth def x
Peripheral vascular disorder def Peripheral vascular disorder def x x
Chills def Chills def x
Oedema peripheral def Oedema peripheral def
Oral disorder def Oral lesion x
Deep vein thrombosis def Deep vein thrombosis def
Migraine def Migraine def x
Hair colour changes Hair discoloration x
High density lipoprotein decreased High density lipoprotein decreased
Injection site inflammation Injection site inflammation
Renal impairment def Kidney function abnormal x
Injection site pain Injection site pain
Pain during injection
Prothrombin level increased Prothrombin level increased x x
Hypogeusia Hypogeusia x
Skin irritation def Skin irritation def x
Enlarged clitoris Enlarged clitoris x
Menstruation irregular def Menstruation irregular def x
Endometrial sarcoma Endometrial stromal sarcoma def
Rash papular Rash papular x
Depression suicidal Depression suicidal x x
Hair growth abnormal Hair growth abnormal
Dermatitis acneiform def Dermatitis acneiform def
Application site oedema Application site oedema x
Skin exfoliation Skin exfoliation x
Hyperaesthesia def Nipple pain
Nipple pain Nipple pain
Activated partial thromboplastin time prolonged PTT prolonged def x x
Activated partial thromboplastin time prolonged x x
Breast tenderness Breast tenderness x
Soft tissue disorder Soft tissue disorder
Electrolyte imbalance def Disorders of fluid, electrolyte and acid-base balance x x
Fluid retention Fluid retention
Blood pressure systolic increased Blood pressure systolic increased
Anaphylactic shock def Anaphylactoid reaction x x
Anaphylactoid reaction Anaphylactoid reaction x x
Depressed mood def Depressed mood def
Haemoglobin abnormal Haemoglobin abnormal
Nipple disorder Nipple disorder
Suicidal ideation def Suicidal ideation def x x
Agitation def Hyperkinesia def
Hyperkinesia def Hyperkinesia def
Red blood cell count increased Red blood cell count increased
Nasal congestion def Nasal oedema x
Nasal oedema Nasal oedema x
Penile pain def Penile pain def
Prostatic adenoma Prostatic adenoma
Influenza like illness Influenza like illness x
Affective disorder def Affective disorder def x
Dissociation Detachment psychological x
Lipids abnormal Lipids abnormal
Blood glucose increased Blood glucose increased x
Blood cholesterol increased Cholesterol serum elevated x x
Abdominal symptom Abdominal symptom x
Blood bilirubin increased def Bilirubin total increased
Arterial disorder def Arterial disorder def x x
International normalised ratio increased def International normalised ratio increased def
Lipids increased Raised serum lipid levels x
Blood testosterone decreased Serum testosterone decreased x
Gingival erythema Redness gum x
Gingival blister Gingival blister x
Impatience Impatience x
Epidermal necrosis Epidermal necrosis x
Sensitisation def Sensitisation def x
Parosmia def Parosmia def
Coronary artery disease def Coronary artery disease def x x
Scar def Scar def x
Breast enlargement Breast enlargement x
Cerebral haemorrhage def Cerebral haemorrhage def
Indication Labels
Adverse reaction def x
Breast cancer def x
Cryptorchism def x x x x x x x x
Delayed puberty def x
Elderly def x
Hypogonadism def x x x x x x x x x
Hypogonadism male def x x x x x x x x
Klinefelter's syndrome def x
Neoplasm def x x x x x x x x x
Neoplasm malignant def x
Orchitis def x x x x x x x x
Primary hypogonadism x x x x x x x x
Puberty def x
Secondary hypogonadism x x x x x x x x
Testosterone deficiency x x
Testosterone low x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: G03BA03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. TESTOSTERONE ENANTHATE / DELATESTRYL : 22 side effects (Drugs@FDA)
  2. testosterone gel / Testim 1% : 25 side effects (FDA CDER)
  3. TESTOSTERONE : 26 side effects (FDA XML label)
  4. TESTOSTERONE : 32 side effects (FDA XML label)
  5. TESTOSTERONE : 41 side effects (FDA XML label)
  6. TESTOSTERONE : 42 side effects (FDA XML label)
  7. testosterone : 48 side effects (FDA XML label)
  8. TESTOSTERONE : 56 side effects (FDA XML label)
  9. TESTOSTERONE CYPIONATE / DEPO-TESTOSTERONE INJ 100MG/ML : 82 side effects (Health Canada)
  10. testosterone : 97 side effects (FDA XML label)