Search results :

Aprepitant

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: A04AD12

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15
Alopecia Alopecia 11.9% - 24% x x x x x x x x x x x
Nausea Nausea 7.1% - 12.7% x x x x
Body temperature increased Body temperature increased 5.9% - 10.6% x x x x x x x x x x x x
Constipation Constipation 2% - 18% x x x x x x x x x x x x x x x
Obstipation x x x x x x x x x x x x x
Pruritus Pruritus postmarketing, 7.6% - 8.4% x x x x x x x x x x x
Decreased appetite Anorexia 0.5% - 10.1% x x x x x x x x x x x x x
Decreased appetite 0.5% - 2% x x x x x x x x x x x x x
Headache Headache 1.8% - 16.4% x x x x x x x x x x x x x x
Diarrhoea Diarrhoea 0.9% - 10.3% x x x x x x x x x x x x x x
Neutropenia Neutropenia 2.9% - 8.9% x x x x x x x x x x x
Hypotension Hypotension 4.6% - 5.7% x x x x x x x x x x x x
Dyspepsia Heartburn 4.9% - 5.3% x x x x x x x x x x x
Dyspepsia 0.4% - 8.4% x x x x x x x x x x x x x x x
Flatulence Flatulence 4.1% - 5.8% x x x x x x x x x x x x x x x
Stomatitis Stomatitis 4.4% - 5.3% x x x x x x x x x x x x x
Hiccups Hiccups 0.2% - 10.8% x x x x x x x x x x x x x x x
Bradycardia Bradycardia 3.9% - 4.4% x x x x x x x x x x x x x x x
Dizziness Dizziness 3.4% - 4.2% x x x x x x x x x x x x x x x
Syncope x x x x x x x
Mediastinal disorder Mediastinal disorder 2.9% - 4.6% x x x x x x x x x x x x x
Tinnitus Tinnitus 3.7% - 3.8% x x x x x x x x x x x x x x x
Gastritis Gastritis 3.1% - 4.2% x x x x x x x x x x x
Epigastric discomfort Epigastric discomfort 3.1% - 4% x x x x x x x x x x x x x
Vomiting Vomiting 2.5% - 3.9% x x x
Insomnia Insomnia 2.1% - 5.6% x x x x x x x x x x x x x x x
Mucosal inflammation Mucosal inflammation 2.5% - 3.5% x x x x x x
Anaemia Anaemia 0% - 4.3% x x x x x x x x x x x x x x x
Urinary tract infection Urinary tract infection 2.3% - 3.2% x x x x x x x x x x
Hypertension Hypertension 2.1% - 3.2% x x x x x x x x x x x x
Laryngeal pain Pharyngolaryngeal pain 2.3% - 3% x x x x x x x x x
Asthenia Asthenia 0.2% - 3.7% x x x x x x x x x x x x x x
Fatigue 0.9% - 21.9% x x x x x x x x x x x x x x x
Menopausal symptoms Hot flush 1.4% - 3% x x x x x x x x x x x x x
Hot flush Hot flush 1.4% - 3% x x x x x x x x x x x x x
Fatigue Fatigue 0.9% - 21.9% x x x x x x x x x x x x x x x
Alanine aminotransferase increased Alanine aminotransferase increased 1.1% - 2.8% x x x x x x x x x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased 0.9% - 1.1% x x x x x x x x x x x x x x x
Eructation Eructation 0.1% - 1% x x x x x x x x x x x x x
Anxiety Anxiety 0% - 0.5% x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis postmarketing x x x x x
Dermatitis Rash postmarketing x x x x x x x x x x x x x x x
Rash Rash postmarketing x x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity postmarketing x x x x x x x x
Immune system disorder Immune system disorder postmarketing x x x x x x x
Nervous system disorder Nervous system disorder postmarketing x x x x x x x x x x x x x
Erythema multiforme Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x x
Urticaria Urticaria postmarketing x x x x x x x x x x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x x x x x x x x
Neurotoxicity Neurotoxicity postmarketing x x
Abdominal distension Abdominal distension x x x
Abdominal pain Abdominal pain x x x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain x x x x x x x x x x x x x x x
Angioedema Angioedema x x x x x x x x x x x x
Anxiety disorder Anxiety disorder x x x x x x x x x x x
Arthralgia Arthralgia x x x x x x x x x
Musculoskeletal discomfort Arthralgia x x x x x x x x x
Myalgia x x x x x x x x x x x x x
Back pain Back pain x x x x x x x x x
Mental disorder Mental disorder x x x x x x x x x x x x x x x
Breast disorder Breast disorder x x x x x x x x x
Candida infection Candida infection x x x x x x x x x x x x x
Oral candidiasis x x x
Oral candidiasis Oral candidiasis x x x
Non-small cell lung cancer Non-small cell lung cancer x x x x x x x x x x x
Cardiovascular disorder Cardiovascular disorder x x x
Cognitive disorder Cognitive disorder x x x x
Infection Infection x x x x x x x x x x x x
Confusional state Confusional state x x x x x x x x x x x
Feeling abnormal Confusional state x x x x x x x x x x x
Malaise x x x x x x x x x x x x x x x
Conjunctivitis Conjunctivitis x x x x x x x x x x x x x
Connective tissue disorder Connective tissue disorder x x x x x x x x x x x x
Cough Cough x x x x x x x x x x x x x x x
Cyst Cyst x x x x x x x x x
Dysphagia Dysphagia x x x x x x x x x x x
Dehydration Dehydration x x x x x x x x x x x
Diabetes mellitus Diabetes mellitus x x x x x x x x x x x
Duodenal ulcer Duodenal ulcer x x x x x x x x x x x x x
Dysarthria Dysarthria x x x x x x x x x x
Osteoarthritis Dysarthria x x x x x x x x x x
Dysgeusia Dysgeusia x x x x x x x x x x x x x x x
Dyspnoea Dyspnoea x x x x x x x x x x x x x x x
Dysuria Dysuria x x x x x x x x x x x x x x x
Oedema Oedema x x x x x x x x x x x x x x x
Embolism Embolism x
Enterocolitis Enterocolitis x x x x x x x
Eye disorder Eye disorder x x x x x x x x x x x x x
Fasting Fasting x
Flushing Flushing x x x x x x x x x x x x x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x x x x x x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x x x x x x x x x x x x x
Glycosuria Glycosuria x x x x x x x x
Hallucination Hallucination x x
Cardiac disorder Cardiac disorder x x x x x x x x x x x x x
Haematoma Haematoma x x x x x x x
Herpes simplex Herpes simplex x x x x x x x x x
Hyperglycaemia Hyperglycaemia x x x x x x x x x x x x x
Hyperhidrosis Hyperhidrosis x x x x
Sweating increased x x x x x x x x x x x
Hypoaesthesia Hypoaesthesia x x x x x x x x x x x x x
Hypokalaemia Hypokalaemia x x x x x x x x x x x x
Hyponatraemia Hyponatraemia x x x x x x x x x x x x x x x
Body temperature decreased Body temperature decreased x x x x x x x
Hypothermia Body temperature decreased x x x x x x x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion x x
Lethargy Lethargy x x x x
Miosis Miosis x x x x x x x x x x
Muscle spasms Cramp muscle x x
Muscle spasms x x
Musculoskeletal pain Musculoskeletal pain x x x x x x x x x x x
Myocardial infarction Myocardial infarction x x x x x x x x x x x
Acute coronary syndrome Myocardial infarction x x x x x x x x x x x
Neoplasm Neoplasm x x x x x x x x x
Pain Pain x x x x x x x
Palpitations Palpitations x x x x x x x x x x x x x
Paraesthesia Paraesthesia x x
Pelvic pain Pelvic pain x x x x x x x x x x x
Neuropathy peripheral Neuropathy peripheral x x x x x x x x x x x
Pharyngitis Pharyngitis x x x x x x x x x x x x x
Pneumonia Pneumonia x x x x x x x x x x x
Polyp Polyp x x x x x x x x x
Polyuria Polyuria x x
Urine output increased Polyuria x x
Urine output increased x x
Upper-airway cough syndrome Postnasal drip x x x x
Proteinuria Proteinuria x x x x x x x x x x x
Protein urine present Proteinuria x x x x x x x x x x x
Prurigo Prurigo x x
Pulmonary embolism Pulmonary embolism x x x x x x x x x x
Respiratory failure Respiratory insufficiency x x x x x x x x x x x
Respiratory tract infection Respiratory tract infection x
Salivary hypersecretion Salivation x x x x x x x x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis x x
Oily skin x x
Convulsion Convulsion x x
Septic shock Septic shock x x x x x x x x x x x
Skin lesion Skin lesion x x x x
Sneezing Sneezing x x x x
Staphylococcal infection Staphylococcal infection x x x x
Shock Syncope x x x x x x x
Syncope Syncope x x x x x x x
Loss of consciousness Syncope x x x x x x x
Loss of consciousness x x
Tachycardia Tachycardia x x x x x x x x x x x
Sinus tachycardia Sinus tachycardia x x x x x x
Thirst Thirst x x
Thrombocytopenia Thrombocytopenia x x x x x x x x x x x
Thrombophlebitis Thrombophlebitis x
Tremor Tremor x x x x x x x x x
Erythema Erythema x
Upper respiratory tract infection Upper respiratory tract infection x x x x x x x x x x
Pollakiuria Pollakiuria x x x x
Urethral disorder Urinary tract disorder x x x x x x x x x x x x
Urinary tract disorder Urinary tract disorder x x x x x x x x x x x x
Angiopathy Angiopathy x x x x x x x x x x x x
Weight increased Weight increased x x
Weight decreased Weight decreased x x x x x x x x x x x x x x x
Wheezing Wheezing x x x x x x x x x x
Dry mouth Dry mouth x x x x x x x x x x x x x
Procedural haemorrhage Intraoperative hemorrhage x x x x x x x
Chills Chills x
Rigors x x x x x x x x x
Polydipsia Polydipsia x x x x
Lower respiratory tract infection Lower respiratory tract infection x x x x x x x x x x x
Deep vein thrombosis Deep vein thrombosis x x x x x x x x x x x
Peripheral sensory neuropathy Peripheral sensory neuropathy x x x x x x x x x x x
Blood urea increased Blood urea increased x x x x x x x x x x x
Mucous membrane disorder Mucous membrane disorder x x x x x x x x x x x
Muscular weakness Muscular weakness x x x x x x x x x x x x x x
Blood alkaline phosphatase increased Phosphatase alkaline increased x x x x x x x x x x x x x
Blood alkaline phosphatase increased x x
Sensory disturbance Sensory disturbance x x x x x x x x x x
Gastrointestinal sounds abnormal Abnormal bowel sounds x x x x x x x x x x
Haemoglobin decreased Haemoglobin decreased x x x x x x x x x x
Malnutrition Malnutrition x x x x x x x x x x x x
Photosensitivity reaction Photosensitivity reaction x x
Photosensitivity x x
Haematuria Blood urine x x x x x x x x x x x x x
Microscopic hematuria x x
Blood urine Blood urine x x x x x x x x x x x x x
Blood urine present Blood urine x x x x x x x x x x x x x
Malaise Malaise x x x x x x x x x x x x x x x
Discomfort Malaise x x x x x x x x x x x x x x x
Ill-defined disorder Malaise x x x x x x x x x x x x x x x
Myalgia Myalgia x x x x x x x x x x x x x
Abdominal pain upper Abdominal pain upper x x x x x x x x x x
Disorientation Disorientation x x x x x x x x x x x x x x x
Visual acuity reduced Visual acuity reduced x x x x x x x x x x
Respiratory depression Respiratory depression x x x x x x x
Pulmonary function test decreased Respiratory depression x x x x x x x
Euphoric mood Euphoric mood x x x x
Abdominal discomfort Upset stomach x x x x x x x x x x
Chest pain Chest discomfort x x x x
Chest discomfort Chest discomfort x x x x
Wound dehiscence Wound dehiscence x x x x x x x
Faeces hard Faeces hard x x x
Blood bilirubin increased Blood bilirubin increased x x x x x x x
Post procedural infection Postoperative infection x x x x x x x
Neutropenic colitis Neutropenic colitis x x x
Blood pressure increased Blood pressure increased x
Hypovolaemia Hypovolaemia x x x x x x x
Altered state of consciousness Depressed level of consciousness x x
Depressed level of consciousness Depressed level of consciousness x x
White blood cells urine positive White blood cells urine positive x x x x x x x x x x x
Gait disturbance Gait disturbance x x x
Blood glucose increased Blood glucose increased x x x x x x x
Throat irritation Throat irritation x x x x
Blood creatinine increased Serum creatinine increased x x x x x x x x x x
Duodenal ulcer perforation Duodenal ulcer perforation x x
Febrile neutropenia Febrile neutropenia x x x x x x x x x x x x x x x
White blood cell count decreased White blood cell count decreased x x x x x x
White blood cell count increased White blood cell count increased x x x x x x x x x x x
Infestation Infestation NOS x x x x x x x x x x x x
Neutrophil count decreased Neutrophil count decreased x x x
Blood potassium decreased Blood potassium decreased x x x x x x x
Blood albumin decreased Blood albumin decreased x x x x x x x
Blood creatine increased Creatine increased x
Neutropenic sepsis Neutropenic sepsis x x x x x x
Infusion site erythema Infusion site erythema x
Subileus Subileus x x x x x x x
Infusion site induration Infusion site induration x
Infusion site pain Infusion site pain x
Infusion site pruritus Infusion site pruritus x
Renal failure Renal impairment x x x x x x x x x x x
Renal impairment Renal impairment x x x x x x x x x x x
Infusion site thrombosis Infusion site thrombophlebitis x
Oropharyngeal pain Oropharyngeal pain x x
Somnolence Somnolence x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

APREPITANT

Side effects:115
Source:FDA Structured Product Label

aprepitant / aprepitant

Side effects:88
Source:EMA

aprepitant / EMEND Capsule

Side effects:122
Source:medicines.org.au

APREPITANT / EMEND

Side effects:81
Source:FDA

APREPITANT / EMEND

Side effects:81
Source:FDA

APREPITANT / EMEND

Side effects:119
Source:FDA

APREPITANT / EMEND TRI-PACK

Side effects:124
Source:Health Canada

APREPITANT / EMEND

Side effects:128
Source:Health Canada

APREPITANT

Side effects:142
Source:FDA Structured Product Label

aprepitant

Side effects:143
Source:FDA Structured Product Label

aprepitant

Side effects:144
Source:FDA Structured Product Label

aprepitant / Emend

Side effects:143
Source:FDA

APREPITANT / EMEND

Side effects:144
Source:FDA

APREPITANT / EMEND

Side effects:144
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label