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ATC Code: L02AE04

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Menopausal symptoms Hot flush 50% - 73% x x x
Hot flush Hot flush 50% - 73% x x x
Bone pain Bone pain 12.1% - 13.2% x x x
Influenza Influenza 0% - 15.8% x
Testicular atrophy Testicular atrophy 7.5% x x
Erectile dysfunction Erectile dysfunction 2.3% - 10% x x x
Oedema Oedema 6.3% x x
Headache Headache postmarketing, 1.7% - 7.5% x x x
Metastatic pain Metastatic pain 5% x
Dysuria Dysuria 4.6% x x
Pain in extremity Pain in extremity 0.8% - 7.5% x x
Leg pain 2.1% - 5.2% x x
Hypertension Hypertension 0.8% - 14.2% x x x
Injection site pain Injection site pain 3.6% - 4% x x
Injection site reaction Injection site reaction 3% x x
Back pain Back pain 0.8% - 10.8% x x x
Nausea Nausea 2.9% x x x
Pain Pain 2.1% - 3.4% x x x
Libido decreased Libido decreased 2.3% - 3% x x x
Disturbance in sexual arousal Libido decreased 2.3% - 3% x x x
Bronchitis Bronchitis 0% - 5% x
Diabetes mellitus Diabetes mellitus 0% - 5% x x x
Hyperglycaemia Hyperglycaemia 0% - 5% x
Arthralgia Arthralgia 0.8% - 7.5% x x x
Musculoskeletal discomfort Arthralgia 0.8% - 7.5% x x x
Myalgia 1.1% x x x
Breast pain Breast pain 2.3% x x
Breast pain male x
Gravitational oedema Gravitational oedema 2.3% x x
Asthenia Fatigue 2.1% - 2.3% x x x
Asthenia 1.1% x x x
Fatigue Fatigue 2.1% - 2.3% x x x
Dizziness Dizziness 1.4% - 2.9% x x x
Insomnia Insomnia 0.8% - 5% x x x
Decreased appetite Anorexia 1.7% x x x
Chest pain Chest pain 1.7% x x x
Constipation Constipation 1.7% x x x
Cough Cough 1.7% x x
Dyspepsia Dyspepsia 1.7% x x
Dermatitis Rash 1.7% x x x
Rash Rash 1.7% x x x
Gynaecomastia Gynaecomastia 1.7% x x x
Muscle spasms Cramps of lower extremities 1.7% x x
Cramp muscle x
Blood alkaline phosphatase increased Phosphatase alkaline increased 1.7% x
Blood alkaline phosphatase increased x
Anaemia Anaemia 1.4% x
Pruritus Pruritus 1.4% x x x
Urinary tract infection Urinary tract infection 0% - 11.6% x x
Mood swings Mood swings 1.4% x x
Affect lability Mood swings 1.4% x x
Diarrhoea Diarrhoea 1.1% - 1.4% x x x
Urinary retention Urinary retention 0% - 5% x x
Abdominal pain Abdominal pain 1.1% x x x
Gastrointestinal pain Abdominal pain 1.1% x x x
Conjunctivitis Conjunctivitis 1.1% x
Dyspnoea Dyspnoea 1.1% x x x
Pharyngitis Pharyngitis 1.1% x x
Oedema peripheral Oedema peripheral 0% - 5% x x
Leg edema x
Eye pain Eye pain 1.1% x x
Myalgia Myalgia 1.1% x x x
Vomiting Vomiting postmarketing, 2.1% x x
Hypersensitivity Hypersensitivity 0.2% x x x
Transient ischaemic attack Transient ischaemic attack postmarketing x
Myocardial infarction Myocardial infarction postmarketing x
Acute coronary syndrome Myocardial infarction postmarketing x
IIIrd nerve paralysis Ophthalmoplegia postmarketing x
Ophthalmoplegia Ophthalmoplegia postmarketing x
Pituitary tumour benign Pituitary adenoma postmarketing x
Pituitary haemorrhage Pituitary apoplexy postmarketing x
Convulsion Convulsion postmarketing x
Shock Shock postmarketing x x
Cerebrovascular accident Cerebrovascular accident postmarketing x
Thrombophlebitis Thrombophlebitis postmarketing x
Deep vein thrombosis Deep vein thrombosis postmarketing x
Mental disorder Mental state abnormal postmarketing x
Mental disorder x x x
Pituitary infarction Pituitary infarction postmarketing x
Embolism Thromboembolic event postmarketing x
Abdominal distension Abdominal distension x
Alopecia Alopecia x
Anaphylactic shock Anaphylactic shock x x
Angioedema Angioedema x x
Anxiety Anxiety x
Bladder neck obstruction Bladder neck obstruction x
Blister Blister x
Dermatitis bullous Blister x
Breast disorder Breast disorder x x
Cardiovascular disorder Cardiovascular disorder x x
Infection Infection x x
Confusional state Confusional state x
Feeling abnormal Confusional state x
Malaise x x
Connective tissue disorder Connective tissue disorder x x
Depression Depression x x
Dysgeusia Dysgeusia x
Endocrine disorder Endocrine disorder x x
Epistaxis Epistaxis x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x
Flatulence Flatulence x
Gastrointestinal disorder Gastrointestinal disorder x x
Gout Gout x
Hyperhidrosis Hyperhidrosis x
Hypotension Hypotension x
Immune system disorder Immune system disorder x
Inflammation Inflammation x
Irritability Irritability x
Lethargy Lethargy x
Lymphocytosis Lymphocytosis x
Mediastinal disorder Mediastinal disorder x
Musculoskeletal disorder Musculoskeletal disorder x
Musculoskeletal pain Musculoskeletal pain x
Nasopharyngitis Nasopharyngitis x
Metastasis Metastasis x
Nervous system disorder Nervous system disorder x x
Osteoarthritis Osteoarthritis x
Palpitations Palpitations x
Paraesthesia Paraesthesia x
Paresthesia lower limb x
Neuropathy peripheral Neuropathy peripheral x
Neuropathy x
Purpura Purpura x
Vascular purpura Purpura x
Rhinitis Rhinitis x
Skin disorder Skin disorder x
Unspecified disorder of skin and subcutaneous tissue x
Spinal cord compression Spinal cord compression x x
Testicular pain Testicular pain x
Tinnitus Tinnitus x
Urethral obstruction Urethral obstruction x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Urticaria Urticaria x
Angiopathy Angiopathy x x
Vertigo Vertigo x
Visual impairment Disorder sight x x
Visual disturbance x
Weight increased Weight increased x
Weight decreased Weight decreased x
Dry mouth Dry mouth x
Orthopnoea Orthopnoea x
Hypokinesia Hypokinesia x
Hepatic function abnormal Hepatic function abnormal x
Blood urea increased Blood urea increased x
Muscular weakness Muscular weakness x x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Joint swelling Joint swelling x
Bone cancer metastatic Bone cancer metastatic x
Haemoglobin decreased Haemoglobin decreased x
Joint stiffness Joint stiffness x
Malnutrition Malnutrition x x
Malaise Malaise x x
Discomfort Malaise x x
Ill-defined disorder Malaise x x
Increased appetite Increased appetite x
Memory impairment Memory impairment x
Euphoric mood Euphoric mood x
Blood creatinine increased Blood creatinine increased x
Condition aggravated Condition aggravated x
Dysstasia Dysstasia x
Blood testosterone decreased Testosterone low x
Ejaculation failure Ejaculation failure x
Vision blurred Vision blurred x
Prostate cancer Prostate cancer x x
Chills Rigors x
Abnormal sensation in eye Abnormal sensation in eye x
Blood pressure increased Blood pressure increased x
Influenza like illness Influenza like illness x
Paralysis Paralysis x
Metastases to spine Metastases to spine x
Acne Acne x
Infestation Infestation NOS x x
Injection site erythema Injection site erythema x
Lymphocyte count increased Lymphocyte count increased x
Local reaction Local reaction x
Tumour flare Tumour flare x
Blood testosterone increased Serum testosterone increased x
Blood glucose increased Glucose increased x
Musculoskeletal stiffness Musculoskeletal stiffness x
Somnolence Somnolence x
Loss of libido Loss of libido x
Hormone-dependent prostate cancer Hormone-dependent prostate cancer x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:62
Source:Health Canada


Side effects:85
Source:FDA Structured Product Label


Side effects:117

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label