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More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: R05DA03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Constipation Constipation 7.95% - 11% 0% x x
Nausea Nausea 7.28% - 9.8% 3.31% x x
Vomiting Vomiting 2.75% - 4.64% 0.662% x x
Urinary tract infection Urinary tract infection 0.784% - 5.3% 1.99% x
Somnolence Somnolence 0.662% - 4.71% 0% x
Drowsiness x
Dizziness Dizziness 1.99% - 3.33% 0.662% x x
Lightheadedness x
Asthenia Fatigue 0.662% - 4.12% 1.32% x
Fatigue Fatigue 0.662% - 4.12% 1.32% x
Back pain Back pain 0.784% - 3.97% 3.31% x
Low back pain x
Upper respiratory tract infection Upper respiratory tract infection 1.37% - 3.31% 0.662% x
Abdominal pain Abdominal pain 1.57% - 2.65% 0% x
Gastrointestinal pain Abdominal pain 1.57% - 2.65% 0% x
Oedema peripheral Oedema peripheral 1.37% - 2.65% 0% x
Muscle spasms Muscle spasms 1.18% - 2.65% 1.32% x x
Headache Headache 0% - 3.73% 1.32% x
Dry mouth Dry mouth 0% - 3.14% 0% x
Tremor Tremor 0.196% - 2.65% 0.662% x
Pruritus Pruritus 0% - 2.55% 0% x x
Agranulocytosis Agranulocytosis x
Anxiety Anxiety x x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Myalgia x
Mental disorder Mental disorder x
Neck pain Neck pain x
Connective tissue disorder Connective tissue disorder x
Contusion Contusion x
Cough Cough x
Dehydration Dehydration x
Dyspnoea Dyspnoea x
Dermatitis Rash x x
Rash Rash x x
Body temperature increased Body temperature increased x
Gastrooesophageal reflux disease Gastrooesophageal reflux disease x
Gastrointestinal disorder Gastrointestinal disorder x
Hyperhidrosis Hyperhidrosis x
Hypersensitivity Hypersensitivity x
Hypokalaemia Hypokalaemia x
Lethargy Lethargy x x
Mediastinal disorder Mediastinal disorder x
Musculoskeletal pain Musculoskeletal pain x
Nervous system disorder Nervous system disorder x
Night sweats Night sweats x
Osteoarthritis Osteoarthritis x
Pain in extremity Pain in extremity x
Paraesthesia Paraesthesia x
Convulsion Convulsion x
Withdrawal syndrome Withdrawal syndrome x
Thrombocytopenia Thrombocytopenia x
Angiopathy Angiopathy x
Muscle strain Muscle strain x
Urinary retention Urinary retention x
Mood swings Mood swings x
Affect lability Mood swings x
Migraine Migraine x
Malnutrition Malnutrition x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Myalgia Myalgia x
Abdominal discomfort Abdominal discomfort x
Dysphoria Dysphoria x
Respiratory depression Respiratory depression x x
Pulmonary function test decreased Respiratory depression x x
Foot fracture Foot fracture x
Joint injury Joint injury x
Ligament sprain Joint sprain x
Non-cardiac chest pain Non-cardiac chest pain x
Laceration Skin laceration x
Menopausal symptoms Hot flush x
Hot flush Hot flush x
Drug interaction Drug interaction x
Hypotension Hypotensive x
Insomnia Insomnia x
Ureteral spasm Ureteral spasm x
Deafness Hearing impaired x
Hearing impaired Hearing impaired x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:20
Source:FDA Structured Product Label


Side effects:59
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label