| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 
| Injection site reaction | Injection site reaction | 33% |  | x |  |  |  |  | x | 
| Muscle spasms | Cramps of lower extremities | 10% |  |  |  |  |  |  | x | 
| Cramp muscle | 0% - 29.4% |  |  |  |  |  | x | x | 
| Infection | Infection | 8% |  |  |  |  |  | x | x | 
| Hypertension | Hypertension | postmarketing, 0.4% - 23% |  |  | x | x | x | x | x | 
| Diarrhoea | Diarrhoea | postmarketing, 2% - 35% |  |  | x | x | x | x | x | 
| Asthenia | Fatigue | 6% |  |  |  |  |  |  | x | 
| Asthenia | 0% - 7% |  |  |  | x | x | x | x | 
| Fatigue | Fatigue | 6% |  |  |  |  |  |  | x | 
| Hyperkalaemia | Hyperkalaemia | 6% |  |  |  |  |  |  | x | 
| Rhinitis | Rhinitis | 6% |  |  |  |  |  |  | x | 
| Dizziness | Syncope | postmarketing, 6% |  | x | x | x | x |  | x | 
| Dizziness | postmarketing, 0% - 13% |  | x | x | x | x | x | x | 
| Lightheadedness | postmarketing |  |  |  |  |  | x | x | 
| Shock | Syncope | postmarketing, 6% |  | x | x | x | x |  | x | 
| Shock | postmarketing |  | x |  | x | x | x | x | 
| Syncope | Syncope | postmarketing, 6% |  | x | x | x | x |  | x | 
| Loss of consciousness | Syncope | postmarketing, 6% |  | x | x | x | x |  | x | 
| Loss of consciousness | postmarketing |  |  |  | x | x | x | x | 
| Thrombosis | Thrombosis | 6% |  |  |  |  |  |  | x | 
| Oedema peripheral | Oedema peripheral | 2.6% - 10.9% |  |  |  |  |  | x | x | 
| Leg edema |  |  |  |  |  |  |  | x | 
| Tachycardia | Tachycardia | postmarketing, 5% - 17% |  | x | x | x | x |  | x | 
| Generalised oedema | Generalised oedema | 5% |  |  |  |  |  |  | x | 
| Fluid retention | Generalised oedema | 5% |  |  |  |  |  |  | x | 
| Nasopharyngitis | Nasopharyngitis | 2.2% - 16% |  |  |  |  |  | x |  | 
| Nausea | Nausea | postmarketing, 1.2% - 14.7% |  | x | x | x | x | x | x | 
| Pain in extremity | Pain in extremity | 0% - 6.5% |  |  |  |  |  | x |  | 
| Pain in arm |  |  |  |  |  |  |  | x | 
| Pharyngitis | Pharyngitis | 2.2% - 16% |  |  |  |  |  | x | x | 
| Sinusitis | Sinusitis | 2.2% - 16% |  |  |  |  |  | x |  | 
| Upper respiratory tract infection | Upper respiratory tract infection | 2.2% - 16% |  |  |  |  |  | x | x | 
| Peritonitis | Peritonitis | 4% |  |  |  |  |  | x |  | 
| Viral infection | Viral infection | 4% |  |  |  |  |  | x |  | 
| Vomiting | Vomiting | postmarketing, 0.4% - 11% |  | x | x | x | x | x | x | 
| Abdominal pain | Abdominal pain | postmarketing, 1.4% - 9% |  | x | x | x | x | x | x | 
| Gastrointestinal pain | Abdominal pain | postmarketing, 1.4% - 9% |  | x | x | x | x | x | x | 
| Arthralgia | Arthralgia | postmarketing, 1.4% - 4.3% |  | x | x | x | x | x | x | 
| Musculoskeletal discomfort | Arthralgia | postmarketing, 1.4% - 4.3% |  | x | x | x | x | x | x | 
| Myalgia | postmarketing, 0% - 3.6% |  | x |  | x | x | x | x | 
| Headache | Headache | postmarketing, 0% - 24% |  | x | x | x | x | x | x | 
| Cough | Cough | 0% - 6% |  |  |  |  |  | x | x | 
| Pruritus | Pruritus | postmarketing, 0% - 6% |  |  | x | x | x | x | x | 
| Hypotension | Hypotension | postmarketing, 0% - 39.4% |  | x | x | x | x | x | x | 
| Arteriovenous fistula thrombosis | Arteriovenous fistula thrombosis | 2% |  |  |  |  |  | x |  | 
| Dyspnoea | Dyspnoea | postmarketing, 1.3% - 11% |  | x | x | x | x | x | x | 
| Back pain | Back pain | postmarketing, 0.4% - 4.3% |  | x | x | x | x | x | x | 
| Body temperature increased | Body temperature increased | postmarketing, 0% - 9% |  | x | x | x | x | x | x | 
| Nasal congestion | Nasal congestion | 0% - 2.2% |  |  |  |  |  | x |  | 
| Fluid overload | Fluid overload | 0% - 3% |  |  |  |  |  | x | x | 
| Constipation | Constipation | 0.5% - 3.2% |  |  | x |  |  |  |  | 
| Hypoglycaemia | Hypoglycaemia | 0% - 4% |  |  |  |  |  | x | x | 
| Pain | Pain | postmarketing, 0.7% - 10% |  |  |  |  | x |  | x | 
| Ache | postmarketing |  |  |  |  |  | x |  | 
| Chest pain | Chest pain | postmarketing, 0% - 10% |  |  |  | x | x | x | x | 
| Chest discomfort | postmarketing |  |  | x |  |  |  |  | 
| Hypersensitivity | Hypersensitivity | postmarketing, 0.5% |  | x | x |  |  |  | x | 
| Alanine aminotransferase increased | Alanine aminotransferase increased | 0% - 1.1% |  |  | x |  |  |  |  | 
| Menopausal symptoms | Hot flush | 0% - 3.6% |  |  | x |  |  |  |  | 
| Hot flush | Hot flush | 0% - 3.6% |  |  | x |  |  |  |  | 
| Blood phosphorus decreased | Phosphorus low | 0% - 2.1% |  |  | x |  |  |  |  | 
| Angioedema | Angioedema | postmarketing |  | x | x |  |  | x |  | 
| Bronchospasm | Bronchospasm | postmarketing |  | x |  | x | x | x |  | 
| Confusional state | Confusional state | postmarketing |  |  |  |  |  | x |  | 
| Feeling abnormal | Confusional state | postmarketing |  |  |  |  |  | x |  | 
| Malaise |  |  |  |  | x | x |  | x | 
| Feeling abnormal | 0% - 3% |  |  |  |  |  | x |  | 
| Dysgeusia | Dysgeusia | postmarketing, 0% - 7.9% |  |  | x |  |  | x | x | 
| Taste altered |  |  |  |  | x | x |  |  | 
| Oedema | Oedema | postmarketing |  |  |  |  |  | x | x | 
| Extravasation | Extravasation | postmarketing |  |  |  |  |  | x |  | 
| Flushing | Flushing | postmarketing, 0% - 3.6% |  | x | x | x | x |  | x | 
| Cardiac failure congestive | Cardiac failure congestive | postmarketing |  |  |  |  |  | x |  | 
| Haemorrhage | Haemorrhage | postmarketing |  |  |  |  |  |  | x | 
| Haemoglobin | Haemorrhage | postmarketing |  |  |  |  |  |  | x | 
| Hyperhidrosis | Hyperhidrosis | postmarketing |  |  |  |  |  | x |  | 
| Sweating |  |  | x |  | x | x |  |  | 
| Sweating increased |  |  |  |  |  |  |  | x | 
| Hypoaesthesia | Hypoaesthesia | postmarketing |  |  |  |  |  |  | x | 
| Numbness |  |  |  |  | x | x |  |  | 
| Hypertonia | Hypertonia | postmarketing |  |  |  |  |  |  | x | 
| Nervousness | Nervousness | postmarketing |  |  |  |  |  |  | x | 
| Tension | Nervousness | postmarketing |  |  |  |  |  |  | x | 
| Osteomalacia | Osteomalacia | postmarketing |  |  | x |  |  |  |  | 
| Pallor | Pallor | postmarketing |  |  |  |  |  |  | x | 
| Paraesthesia | Paraesthesia | postmarketing, 6% |  |  | x | x | x | x | x | 
| Phlebitis | Phlebitis | postmarketing |  |  |  | x | x |  | x | 
| Convulsion | Convulsion | postmarketing |  |  |  | x | x | x | x | 
| Swelling | Swelling | postmarketing |  |  |  | x | x | x |  | 
| Erythema | Erythema | postmarketing |  |  | x |  |  |  |  | 
| Redness |  |  |  |  |  |  |  | x | 
| Urticaria | Urticaria | postmarketing |  | x | x | x | x |  | x | 
| Dry mouth | Dry mouth | postmarketing |  |  |  |  |  |  | x | 
| Chills | Chills | postmarketing |  | x | x | x | x |  | x | 
| Shivering |  |  |  |  | x | x |  |  | 
| Rigors |  |  |  |  |  |  |  | x | 
| Skin discolouration | Skin discolouration | postmarketing |  |  |  |  |  |  | x | 
| Chest discomfort | Chest discomfort | postmarketing |  |  | x |  |  |  |  | 
| Chest tightness |  |  |  |  | x | x |  |  | 
| Sepsis | Sepsis | postmarketing |  |  |  |  |  | x | x | 
| Drug intolerance | Drug intolerance | postmarketing |  |  |  |  |  |  | x | 
| Bradycardia | Bradycardia | postmarketing |  |  |  | x | x | x | x | 
| Chromaturia | Chromaturia | postmarketing |  |  |  |  |  | x |  | 
| Local swelling | Peripheral swelling | postmarketing |  |  |  |  |  |  | x | 
| Injection site discolouration | Injection site discolouration | postmarketing, 0% - 1.4% |  |  | x |  |  | x |  | 
| Myalgia | Myalgia | postmarketing, 0% - 3.6% |  | x |  | x | x | x | x | 
| Abscess | Abscess |  |  |  |  | x | x |  | x | 
| Anaphylactic shock | Anaphylactic shock |  |  | x |  | x | x |  |  | 
| Anaphylactoid reaction |  |  |  |  | x | x |  |  | 
| Anaemia | Anaemia |  |  |  |  |  |  |  | x | 
| Angina pectoris | Angina pectoris |  |  |  |  |  |  |  | x | 
| Decreased appetite | Anorexia |  |  |  |  |  |  |  | x | 
| Arcus lipoides | Arcus senilis |  |  |  |  |  |  |  | x | 
| Arrhythmia | Arrhythmia |  |  |  |  | x | x |  |  | 
| Arthritis | Arthritis |  |  |  |  | x | x |  |  | 
| Rheumatoid arthritis |  |  |  |  | x | x |  |  | 
| Rheumatoid arthritis | Rheumatoid arthritis |  |  |  |  | x | x |  |  | 
| Neoplasm malignant | Carcinoma |  |  |  |  |  |  |  | x | 
| Cellulitis | Cellulitis |  |  |  |  | x | x |  |  | 
| Conjunctivitis | Conjunctivitis | 0% - 2.7% |  |  |  |  |  | x | x | 
| Cyanosis | Cyanosis |  |  |  |  | x | x |  |  | 
| Deafness | Deafness |  |  |  |  |  |  |  | x | 
| Diplopia | Diplopia |  |  |  |  |  |  |  | x | 
| Dyspepsia | Dyspepsia |  |  |  |  |  |  |  | x | 
| Ear pain | Ear pain | 0% - 2.2% |  |  |  |  |  | x |  | 
| Eructation | Eructation |  |  |  |  |  |  |  | x | 
| Dermatitis | Rash |  |  | x | x | x | x |  | x | 
| Rash | Rash |  |  | x | x | x | x |  | x | 
| Eye disorder | Eye disorder |  |  |  |  |  |  | x |  | 
| Fibrosis | Fibrosis |  |  |  |  |  | x |  |  | 
| Flatulence | Flatulence |  |  |  |  |  |  |  | x | 
| Gastrointestinal disorder | Gastrointestinal disorder |  |  |  |  |  |  | x | x | 
| Gout | Gout | 0% - 2.9% |  |  |  |  |  | x |  | 
| Cardiac arrest | Cardiac arrest |  |  |  |  | x | x |  |  | 
| Haematuria | Haematuria |  |  |  |  | x | x |  |  | 
| Hyperglycaemia | Hyperglycaemia | 0% - 2.9% |  |  |  |  |  | x |  | 
| Hypokalaemia | Hypokalaemia |  |  |  |  |  |  |  | x | 
| Inflammation | Inflammation |  |  | x |  | x | x |  |  | 
| Leukocytosis | Leukocytosis |  |  |  |  | x | x |  | x | 
| Mediastinal disorder | Mediastinal disorder |  |  |  |  |  |  | x |  | 
| Melaena | Melaena |  |  |  |  |  |  |  | x | 
| Myocardial infarction | Myocardial infarction |  |  |  |  |  |  |  | x | 
| Acute coronary syndrome | Myocardial infarction |  |  |  |  |  |  |  | x | 
| Nervous system disorder | Nervous system disorder |  |  |  |  |  |  | x |  | 
| Sensory loss | Numbness |  |  |  |  | x | x |  |  | 
| Pneumonia | Pneumonia |  |  |  |  |  |  |  | x | 
| Pulmonary oedema | Pulmonary oedema |  |  |  |  |  |  |  | x | 
| Purpura | Purpura |  |  |  |  | x | x |  |  | 
| Vascular purpura | Purpura |  |  |  |  | x | x |  |  | 
| Anorectal disorder | Rectal disorder |  |  |  |  |  |  |  | x | 
| Sneezing | Sneezing |  |  |  | x |  |  |  |  | 
| Urinary tract infection | Urinary tract infection |  |  |  |  |  |  |  | x | 
| Angiopathy | Angiopathy |  |  |  |  |  |  | x |  | 
| Wheezing | Wheezing |  |  |  |  | x | x |  |  | 
| Agitation | Agitation |  |  |  |  |  |  |  | x | 
| Gamma-glutamyltransferase increased | Gamma-glutamyltransferase increased |  |  |  | x |  |  |  |  | 
| Injection site pain | Injection site pain |  |  | x | x |  |  |  |  | 
| Respiratory arrest | Respiratory arrest |  |  |  |  | x | x |  |  | 
| Malnutrition | Malnutrition |  |  |  |  |  |  | x | x | 
| Malaise | Malaise |  |  |  |  | x | x |  | x | 
| Discomfort | Malaise |  |  |  |  | x | x |  | x | 
| Ill-defined disorder | Malaise |  |  |  |  | x | x |  | x | 
| Disorientation | Disorientation |  |  |  |  | x | x |  |  | 
| Tenderness | Tenderness |  |  |  |  |  | x |  |  | 
| Graft complication | Graft complication | 0% - 9.5% |  |  |  |  |  | x |  | 
| Atrophy | Atrophy |  |  |  |  |  | x |  |  | 
| Anaphylactoid reaction | Anaphylactoid reaction |  |  |  |  | x | x |  |  | 
| Lymphadenopathy | Generalized lymphadenopathy |  |  | x |  |  |  |  |  | 
| Lymphadenopathy |  |  |  |  | x | x |  | x | 
| Lymphadenopathy inguinal |  |  | x |  |  |  |  |  | 
| Injection site extravasation | Injection site extravasation | 0% - 2.2% |  |  |  |  |  | x |  | 
| Eyelid oedema | Swelling of eyelid |  |  |  |  |  |  |  | x | 
| Infestation | Infestation NOS |  |  |  |  |  |  | x |  | 
| Infusion site pain | Infusion site pain | 0% - 5.8% |  |  |  |  |  | x |  | 
| Somnolence | Somnolence |  |  |  |  |  |  |  | x | 
| Lacrimation increased | Tearing eyes |  |  |  |  |  |  |  | x |