Gadolinium
  
Side effects 
	
		
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| MedDRA Preferred Term | Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 
| Discomfort | Discomfort | 26.4% |  |  |  |  | x |  | x | x | 
| Malaise | postmarketing |  |  | x | x | x | x | x | x | 
| Dysgeusia | Dysgeusia | 0.4% - 6.2% |  | x | x | x | x | x | x | x | 
| Dizziness | Dizziness | 0.5% - 3.74% |  | x |  | x | x | x | x | x | 
| Syncope | postmarketing |  |  |  |  |  | x |  | x | 
| Paraesthesia | Paraesthesia | 0.1% - 2.22% |  | x | x | x | x | x | x | x | 
| Diarrhoea | Diarrhoea | postmarketing, 1.91% |  |  |  |  |  | x | x | x | 
| Asthenia | Asthenia | 1.53% |  |  |  |  |  |  |  | x | 
| Fatigue | 0.2% |  |  |  |  | x | x |  |  | 
| Rhinitis | Rhinitis | postmarketing, 1.53% |  |  |  |  | x |  |  | x | 
| Headache | Headache | 0.5% - 9.4% |  | x | x | x | x | x | x | x | 
| Nausea | Nausea | 0.6% - 3.21% |  | x | x | x | x | x | x | x | 
| Back pain | Back pain | 0.6% - 1.22% |  |  |  |  | x |  |  | x | 
| Dyspepsia | Dyspepsia | 1.22% |  |  |  |  |  |  |  | x | 
| Pain | Pain | postmarketing, 0.4% - 1.83% |  |  |  |  | x |  | x | x | 
| Body temperature increased | Body temperature increased | postmarketing, 0.9% |  |  |  |  |  | x | x | x | 
| Vomiting | Vomiting | 0.3% - 1.4% |  |  | x | x | x | x | x | x | 
| Injection site reaction | Injection site reaction | postmarketing, 0.3% - 1.53% |  |  | x | x | x | x | x | x | 
| Injection site pain | Injection site pain | 0.4% |  |  |  |  |  | x |  |  | 
| Feeling cold | Coldness | 0.4% |  |  |  |  | x |  |  |  | 
| Feeling hot | Feeling hot | 0.4% - 0.8% |  |  | x | x | x |  | x |  | 
| Warmth |  |  |  |  |  |  | x |  |  | 
| Dermatitis | Rash | 0.3% |  |  | x | x | x | x | x |  | 
| Rash | Rash | 0.3% |  |  | x | x | x | x | x |  | 
| Flushing | Flushing | 0.3% |  |  | x | x | x |  |  |  | 
| Dyspnoea | Dyspnoea | 0.2% |  |  | x | x | x |  | x | x | 
| Fatigue | Fatigue | 0.2% |  |  |  |  | x | x |  |  | 
| Pruritus | Pruritus | 0.2% - 0.3% |  | x | x | x | x | x | x | x | 
| Erythema | Erythema | 0.2% |  |  | x | x |  |  |  |  | 
| Respiratory distress | Respiratory distress | 0.2% |  |  |  |  | x |  |  |  | 
| Injection site coldness | Injection site coldness | 0.2% |  |  |  |  |  | x |  |  | 
| Vertigo | Vertigo | 0.1% |  | x |  |  | x |  |  | x | 
| Dry mouth | Dry mouth | 0.1% |  |  | x | x | x |  | x | x | 
| Chills | Chills | 0.1% |  |  |  |  | x |  | x |  | 
| Feeling abnormal | Feeling abnormal | 0.1% |  |  |  |  | x |  |  |  | 
| Malaise | postmarketing |  |  | x | x | x | x | x | x | 
| Confusional state |  |  |  |  |  |  |  |  | x | 
| Abdominal pain | Abdominal pain | postmarketing |  |  |  |  | x |  | x |  | 
| Gastrointestinal pain | Abdominal pain | postmarketing |  |  |  |  | x |  | x |  | 
| Anaphylactic shock | Anaphylactic shock | postmarketing |  | x |  |  |  |  | x |  | 
| Anaphylactoid reaction | postmarketing |  | x | x | x | x | x | x |  | 
| Angioedema | Angioedema | postmarketing |  |  | x | x |  | x |  |  | 
| Arrhythmia | Arrhythmia | postmarketing |  |  |  |  |  | x |  | x | 
| Blister | Blister | postmarketing |  |  |  |  |  |  | x |  | 
| Dermatitis bullous | Blister | postmarketing |  |  |  |  |  |  | x |  | 
| Bronchospasm | Bronchospasm | postmarketing |  |  | x | x |  | x |  |  | 
| Chest pain | Chest pain | postmarketing, 0.1% |  |  | x | x | x |  | x | x | 
| Coma | Coma | postmarketing |  |  |  |  |  | x |  |  | 
| Conjunctivitis | Conjunctivitis | postmarketing |  |  | x | x | x | x |  | x | 
| Connective tissue disorder | Connective tissue disorder | postmarketing |  |  |  |  |  | x | x |  | 
| Muscle contracture | Muscle contracture | postmarketing |  |  |  |  |  | x |  |  | 
| Cough | Cough | postmarketing |  |  | x | x | x |  |  | x | 
| Cyanosis | Cyanosis | postmarketing |  |  | x | x |  | x |  |  | 
| Oedema | Oedema | postmarketing |  |  |  |  | x |  |  | x | 
| Extravasation | Extravasation | postmarketing, 0.4% |  |  |  |  | x | x | x |  | 
| Gastrointestinal disorder | Gastrointestinal disorder | postmarketing |  |  |  |  |  | x | x |  | 
| Cardiac arrest | Cardiac arrest | postmarketing |  |  | x | x |  | x |  |  | 
| Cardiac disorder | Cardiac disorder | postmarketing |  |  |  |  |  | x | x |  | 
| Hyperhidrosis | Hyperhidrosis | postmarketing, 0.9% |  |  | x | x | x | x | x |  | 
| Sweating increased |  |  |  |  |  |  |  |  | x | 
| Hypersensitivity | Hypersensitivity | postmarketing, 0.2% |  | x | x | x | x | x | x | x | 
| Hypoaesthesia | Hypoaesthesia | postmarketing |  |  |  |  | x |  |  | x | 
| Numbness |  |  |  |  |  |  |  |  | x | 
| Hypotension | Hypotension | postmarketing |  |  | x | x | x |  |  | x | 
| Immune system disorder | Immune system disorder | postmarketing |  |  |  |  |  | x | x |  | 
| Laryngeal oedema | Laryngeal oedema | postmarketing |  |  | x | x |  |  |  |  | 
| Laryngospasm | Laryngospasm | postmarketing |  |  |  |  |  | x | x | x | 
| Necrosis | Necrosis | postmarketing |  |  |  |  |  |  | x |  | 
| Nervous system disorder | Nervous system disorder | postmarketing |  |  |  |  |  | x | x |  | 
| Pallor | Pallor | postmarketing |  |  | x | x | x |  |  | x | 
| Pulmonary oedema | Pulmonary oedema | postmarketing |  |  | x | x |  |  | x |  | 
| Convulsion | Convulsion | postmarketing |  |  | x | x |  | x | x |  | 
| Shock | Shock | postmarketing |  |  | x | x | x |  |  |  | 
| Syncope | postmarketing |  |  |  |  |  | x |  | x | 
| Salivary hypersecretion | Salivary hypersecretion | postmarketing |  |  |  |  | x | x |  | x | 
| Sneezing | Sneezing | postmarketing |  |  | x | x | x |  | x |  | 
| Swelling | Swelling | postmarketing |  |  |  |  |  |  | x |  | 
| Syncope | Syncope | postmarketing |  |  |  |  |  | x |  | x | 
| Loss of consciousness | Syncope | postmarketing |  |  |  |  |  | x |  | x | 
| Loss of consciousness | postmarketing |  |  | x | x |  |  | x |  | 
| Tachycardia | Tachycardia | postmarketing |  |  | x | x | x | x |  | x | 
| Tremor | Tremor | postmarketing |  |  |  |  | x | x | x | x | 
| Urticaria | Urticaria | postmarketing |  |  | x | x | x | x | x | x | 
| Angiopathy | Angiopathy | postmarketing |  |  |  |  |  | x |  |  | 
| Burning sensation | Burning sensation | postmarketing, 0.2% |  | x | x | x |  | x | x |  | 
| Agitation | Agitation | postmarketing |  |  |  |  | x |  |  | x | 
| Muscular weakness | Muscular weakness | postmarketing |  |  |  |  |  | x |  |  | 
| Myasthenia |  |  |  |  |  |  |  |  | x | 
| Lacrimation increased | Lacrimation increased | postmarketing |  |  |  |  |  | x |  |  | 
| Endophthalmitis | Ocular hyperaemia | postmarketing |  |  |  |  |  | x | x |  | 
| Ocular hyperaemia | Ocular hyperaemia | postmarketing |  |  |  |  |  | x | x |  | 
| Eyelid oedema | Eyelid oedema | postmarketing |  |  | x | x |  | x |  |  | 
| Respiratory arrest | Respiratory arrest | postmarketing |  |  | x | x |  | x |  |  | 
| Skin disorder | Unspecified disorder of skin and subcutaneous tissue | postmarketing |  |  |  |  |  | x | x |  | 
| Malaise | Malaise | postmarketing |  |  | x | x | x | x | x | x | 
| Ill-defined disorder | Malaise | postmarketing |  |  | x | x | x | x | x | x | 
| Pharyngeal oedema | Pharyngeal oedema | postmarketing |  |  |  |  |  | x |  |  | 
| Anaphylactoid reaction | Anaphylactoid reaction | postmarketing |  | x | x | x | x | x | x |  | 
| Bradycardia | Bradycardia | postmarketing |  |  |  |  |  | x |  |  | 
| Blood pressure increased | Blood pressure increased | postmarketing, 0.4% |  |  | x | x | x |  |  |  | 
| Face oedema | Face oedema | postmarketing |  |  | x | x | x |  |  | x | 
| Presyncope | Presyncope | postmarketing |  |  |  |  |  | x |  |  | 
| Phlebitis superficial | Phlebitis superficial | postmarketing |  |  |  |  |  | x |  |  | 
| Oropharyngeal swelling | Oropharyngeal swelling | postmarketing |  |  | x | x |  |  |  |  | 
| Parosmia | Parosmia | postmarketing, 0.3% |  |  | x | x | x | x | x | x | 
| Nephrogenic systemic fibrosis | Nephrogenic systemic fibrosis | postmarketing |  | x | x | x | x |  | x |  | 
| Amblyopia | Amblyopia |  |  |  |  |  |  |  |  | x | 
| Decreased appetite | Anorexia |  |  |  |  |  |  |  |  | x | 
| Anxiety | Anxiety |  |  |  |  |  |  | x |  | x | 
| Arthralgia | Arthralgia |  |  |  |  |  |  |  |  | x | 
| Musculoskeletal discomfort | Arthralgia |  |  |  |  |  |  |  |  | x | 
| Myalgia |  |  |  |  |  |  |  | x | x | 
| Asthma | Asthma |  |  |  |  |  |  |  |  | x | 
| Bundle branch block | Bundle branch block |  |  |  |  |  | x |  |  |  | 
| Neck pain | Neck pain |  |  |  |  |  |  |  |  | x | 
| Confusional state | Confusional state |  |  |  |  |  |  |  |  | x | 
| Constipation | Constipation |  |  |  |  |  |  |  |  | x | 
| Dysphagia | Dysphagia |  |  |  |  |  |  |  |  | x | 
| Depersonalisation | Depersonalisation |  |  |  |  |  |  |  |  | x | 
| Diplopia | Diplopia |  |  |  |  |  |  |  |  | x | 
| Dysuria | Dysuria |  |  |  |  |  |  |  |  | x | 
| Epistaxis | Epistaxis |  |  |  |  |  |  |  |  | x | 
| Eructation | Eructation |  |  |  |  |  |  |  |  | x | 
| Erythema multiforme | Erythema multiforme |  |  |  |  |  |  |  |  | x | 
| Eye disorder | Eye disorder |  |  |  |  |  |  |  | x |  | 
| Flatulence | Flatulence |  |  |  |  |  |  |  |  | x | 
| Glioma | Glioma |  |  |  |  |  |  |  | x |  | 
| Hallucination | Hallucination |  |  |  |  |  |  |  |  | x | 
| Haemoptysis | Haemoptysis |  |  |  |  |  |  |  |  | x | 
| Hypercalcaemia | Hypercalcaemia |  |  |  |  |  |  |  |  | x | 
| Hyperglycaemia | Hyperglycaemia |  |  |  |  |  |  |  |  | x | 
| Hypertension | Hypertension |  |  | x |  |  |  | x |  | x | 
| Hypoglycaemia | Hypoglycaemia |  |  |  |  |  |  |  |  | x | 
| Hyponatraemia | Hyponatraemia |  |  |  |  |  |  |  |  | x | 
| Inflammation | Inflammation |  |  |  |  |  |  | x |  |  | 
| Eye pruritus | Eye pruritus |  |  |  |  |  |  |  | x |  | 
| Muscle spasms | Cramps of lower extremities |  |  |  |  |  |  |  |  | x | 
| Muscle spasms |  |  |  |  |  |  |  |  | x | 
| Mediastinal disorder | Mediastinal disorder |  |  |  |  |  |  |  | x |  | 
| Hypertonia | Hypertonia |  |  |  |  |  |  |  |  | x | 
| Nasal congestion | Nasal congestion |  |  |  |  |  |  |  | x |  | 
| Nervousness | Nervousness |  |  |  |  |  |  |  |  | x | 
| Tension | Nervousness |  |  |  |  |  |  |  |  | x | 
| Sensory loss | Numbness |  |  |  |  |  |  |  |  | x | 
| Oliguria | Oliguria |  |  |  |  |  |  |  |  | x | 
| Pain in extremity | Pain in extremity |  |  |  |  |  |  | x |  |  | 
| Palpitations | Palpitations |  |  |  | x | x | x | x |  | x | 
| Pelvic pain | Pelvic pain |  |  |  |  |  |  |  |  | x | 
| Pharyngitis | Pharyngitis |  |  |  |  |  |  |  |  | x | 
| Hyperacusis | Hyperacusis |  |  |  |  |  |  |  |  | x | 
| Sinusitis | Sinusitis |  |  |  |  |  |  |  |  | x | 
| Thirst | Thirst |  |  |  |  |  |  |  |  | x | 
| Thrombocytopenia | Thrombocytopenia |  |  |  |  |  |  |  |  | x | 
| Thrombophlebitis | Thrombophlebitis |  |  |  |  |  |  |  |  | x | 
| Tinnitus | Tinnitus |  |  |  |  |  |  |  |  | x | 
| Wheezing | Wheezing |  |  |  |  |  |  |  | x |  | 
| Atrioventricular block first degree | Atrioventricular block first degree |  |  |  |  |  |  |  | x |  | 
| Vasospasm | Vasospasm |  |  |  |  |  |  |  |  | x | 
| Musculoskeletal stiffness | Neck stiffness |  |  |  |  |  |  |  |  | x | 
| Nuchal rigidity | Neck stiffness |  |  |  |  |  |  |  |  | x | 
| Application site reaction | Application site reaction |  |  |  |  |  |  |  |  | x | 
| Blood creatinine increased | Creatinine increased |  |  |  |  |  |  |  |  | x | 
| Serum creatinine increased |  |  |  |  |  |  | x |  |  | 
| Swelling face | Swelling face |  |  |  |  |  |  |  | x |  | 
| Injection site swelling | Injection site swelling |  |  |  |  |  |  |  |  | x | 
| Tongue disorder | Tongue oedema |  |  |  |  |  |  |  | x |  | 
| Tongue oedema | Tongue oedema |  |  |  |  |  |  |  | x |  | 
| Injection site inflammation | Injection site inflammation |  |  |  |  |  |  |  |  | x | 
| Dry skin | Dry skin |  |  |  |  |  |  |  |  | x | 
| Rash macular | Rash macular |  |  |  |  |  |  |  |  | x | 
| Myalgia | Myalgia |  |  |  |  |  |  |  | x | x | 
| Increased appetite | Increased appetite |  |  |  |  |  |  |  |  | x | 
| Lip swelling | Lip swelling |  |  |  |  |  |  |  | x |  | 
| Pancreatitis necrotising | Pancreatitis necrotising |  |  |  |  |  |  |  | x |  | 
| Eye swelling | Eye swelling |  |  |  |  |  |  |  | x |  | 
| Akathisia | Akathisia |  |  |  |  |  | x |  |  |  | 
| Oral discomfort | Oral discomfort |  |  |  |  |  | x |  |  |  | 
| Rash maculo-papular | Rash maculo-papular |  |  |  |  |  | x |  |  |  | 
| Injection site haemorrhage | Injection site bruising |  |  | x |  |  |  |  |  |  | 
| Injection site bruising | Injection site bruising |  |  | x |  |  |  |  |  |  | 
| Paraesthesia oral | Paraesthesia oral |  |  |  |  |  |  |  | x |  | 
| Visual impairment | Visual disturbance |  |  |  |  |  |  |  | x |  | 
| Basophilia | Basophilia |  |  |  |  |  |  |  | x |  | 
| Vessel puncture site bruise | Venipuncture site bruise |  |  | x |  |  |  |  |  |  | 
| Oropharyngeal discomfort | Oropharyngeal discomfort |  |  |  |  |  |  | x |  |  | 
| Renal failure acute | Acute kidney injury |  |  |  |  |  |  | x |  |  | 
| Somnolence | Somnolence |  |  |  |  |  |  | x |  | x | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 15 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 43 | 
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		| Source: | FDA Structured Product Label | 
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		| Side effects: | 44 | 
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		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 52 | 
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		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 62 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 62 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 89 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |