Gadolinium
Side effects
Options:
Hide MedDRA Preferred Terms
MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
Discomfort
|
Discomfort
|
26.4%
|
|
|
|
|
x
|
|
x
|
x
|
Malaise
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Dysgeusia
|
Dysgeusia
|
0.4% - 6.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
Dizziness
|
0.5% - 3.74%
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
Syncope
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Paraesthesia
|
Paraesthesia
|
0.1% - 2.22%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Diarrhoea
|
Diarrhoea
|
postmarketing, 1.91%
|
|
|
|
|
|
x
|
x
|
x
|
Asthenia
|
Asthenia
|
1.53%
|
|
|
|
|
|
|
|
x
|
Fatigue
|
0.2%
|
|
|
|
|
x
|
x
|
|
|
Rhinitis
|
Rhinitis
|
postmarketing, 1.53%
|
|
|
|
|
x
|
|
|
x
|
Headache
|
Headache
|
0.5% - 9.4%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Nausea
|
Nausea
|
0.6% - 3.21%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Back pain
|
Back pain
|
0.6% - 1.22%
|
|
|
|
|
x
|
|
|
x
|
Dyspepsia
|
Dyspepsia
|
1.22%
|
|
|
|
|
|
|
|
x
|
Pain
|
Pain
|
postmarketing, 0.4% - 1.83%
|
|
|
|
|
x
|
|
x
|
x
|
Body temperature increased
|
Body temperature increased
|
postmarketing, 0.9%
|
|
|
|
|
|
x
|
x
|
x
|
Vomiting
|
Vomiting
|
0.3% - 1.4%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Injection site reaction
|
Injection site reaction
|
postmarketing, 0.3% - 1.53%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Injection site pain
|
Injection site pain
|
0.4%
|
|
|
|
|
|
x
|
|
|
Feeling cold
|
Coldness
|
0.4%
|
|
|
|
|
x
|
|
|
|
Feeling hot
|
Feeling hot
|
0.4% - 0.8%
|
|
|
x
|
x
|
x
|
|
x
|
|
Warmth
|
|
|
|
|
|
|
x
|
|
|
Dermatitis
|
Rash
|
0.3%
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Rash
|
Rash
|
0.3%
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Flushing
|
Flushing
|
0.3%
|
|
|
x
|
x
|
x
|
|
|
|
Dyspnoea
|
Dyspnoea
|
0.2%
|
|
|
x
|
x
|
x
|
|
x
|
x
|
Fatigue
|
Fatigue
|
0.2%
|
|
|
|
|
x
|
x
|
|
|
Pruritus
|
Pruritus
|
0.2% - 0.3%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Erythema
|
Erythema
|
0.2%
|
|
|
x
|
x
|
|
|
|
|
Respiratory distress
|
Respiratory distress
|
0.2%
|
|
|
|
|
x
|
|
|
|
Injection site coldness
|
Injection site coldness
|
0.2%
|
|
|
|
|
|
x
|
|
|
Vertigo
|
Vertigo
|
0.1%
|
|
x
|
|
|
x
|
|
|
x
|
Dry mouth
|
Dry mouth
|
0.1%
|
|
|
x
|
x
|
x
|
|
x
|
x
|
Chills
|
Chills
|
0.1%
|
|
|
|
|
x
|
|
x
|
|
Feeling abnormal
|
Feeling abnormal
|
0.1%
|
|
|
|
|
x
|
|
|
|
Malaise
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Confusional state
|
|
|
|
|
|
|
|
|
x
|
Abdominal pain
|
Abdominal pain
|
postmarketing
|
|
|
|
|
x
|
|
x
|
|
Gastrointestinal pain
|
Abdominal pain
|
postmarketing
|
|
|
|
|
x
|
|
x
|
|
Anaphylactic shock
|
Anaphylactic shock
|
postmarketing
|
|
x
|
|
|
|
|
x
|
|
Anaphylactoid reaction
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Angioedema
|
Angioedema
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Arrhythmia
|
Arrhythmia
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Blister
|
Blister
|
postmarketing
|
|
|
|
|
|
|
x
|
|
Dermatitis bullous
|
Blister
|
postmarketing
|
|
|
|
|
|
|
x
|
|
Bronchospasm
|
Bronchospasm
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Chest pain
|
Chest pain
|
postmarketing, 0.1%
|
|
|
x
|
x
|
x
|
|
x
|
x
|
Coma
|
Coma
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Conjunctivitis
|
Conjunctivitis
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
|
x
|
Connective tissue disorder
|
Connective tissue disorder
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Muscle contracture
|
Muscle contracture
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Cough
|
Cough
|
postmarketing
|
|
|
x
|
x
|
x
|
|
|
x
|
Cyanosis
|
Cyanosis
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Oedema
|
Oedema
|
postmarketing
|
|
|
|
|
x
|
|
|
x
|
Extravasation
|
Extravasation
|
postmarketing, 0.4%
|
|
|
|
|
x
|
x
|
x
|
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Cardiac arrest
|
Cardiac arrest
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Hyperhidrosis
|
Hyperhidrosis
|
postmarketing, 0.9%
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Sweating increased
|
|
|
|
|
|
|
|
|
x
|
Hypersensitivity
|
Hypersensitivity
|
postmarketing, 0.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypoaesthesia
|
Hypoaesthesia
|
postmarketing
|
|
|
|
|
x
|
|
|
x
|
Numbness
|
|
|
|
|
|
|
|
|
x
|
Hypotension
|
Hypotension
|
postmarketing
|
|
|
x
|
x
|
x
|
|
|
x
|
Immune system disorder
|
Immune system disorder
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Laryngeal oedema
|
Laryngeal oedema
|
postmarketing
|
|
|
x
|
x
|
|
|
|
|
Laryngospasm
|
Laryngospasm
|
postmarketing
|
|
|
|
|
|
x
|
x
|
x
|
Necrosis
|
Necrosis
|
postmarketing
|
|
|
|
|
|
|
x
|
|
Nervous system disorder
|
Nervous system disorder
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Pallor
|
Pallor
|
postmarketing
|
|
|
x
|
x
|
x
|
|
|
x
|
Pulmonary oedema
|
Pulmonary oedema
|
postmarketing
|
|
|
x
|
x
|
|
|
x
|
|
Convulsion
|
Convulsion
|
postmarketing
|
|
|
x
|
x
|
|
x
|
x
|
|
Shock
|
Shock
|
postmarketing
|
|
|
x
|
x
|
x
|
|
|
|
Syncope
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Salivary hypersecretion
|
Salivary hypersecretion
|
postmarketing
|
|
|
|
|
x
|
x
|
|
x
|
Sneezing
|
Sneezing
|
postmarketing
|
|
|
x
|
x
|
x
|
|
x
|
|
Swelling
|
Swelling
|
postmarketing
|
|
|
|
|
|
|
x
|
|
Syncope
|
Syncope
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Loss of consciousness
|
Syncope
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Loss of consciousness
|
postmarketing
|
|
|
x
|
x
|
|
|
x
|
|
Tachycardia
|
Tachycardia
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
|
x
|
Tremor
|
Tremor
|
postmarketing
|
|
|
|
|
x
|
x
|
x
|
x
|
Urticaria
|
Urticaria
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Angiopathy
|
Angiopathy
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Burning sensation
|
Burning sensation
|
postmarketing, 0.2%
|
|
x
|
x
|
x
|
|
x
|
x
|
|
Agitation
|
Agitation
|
postmarketing
|
|
|
|
|
x
|
|
|
x
|
Muscular weakness
|
Muscular weakness
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Myasthenia
|
|
|
|
|
|
|
|
|
x
|
Lacrimation increased
|
Lacrimation increased
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Endophthalmitis
|
Ocular hyperaemia
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Ocular hyperaemia
|
Ocular hyperaemia
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Eyelid oedema
|
Eyelid oedema
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Respiratory arrest
|
Respiratory arrest
|
postmarketing
|
|
|
x
|
x
|
|
x
|
|
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
|
|
|
|
x
|
x
|
|
Malaise
|
Malaise
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Ill-defined disorder
|
Malaise
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Pharyngeal oedema
|
Pharyngeal oedema
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Anaphylactoid reaction
|
Anaphylactoid reaction
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bradycardia
|
Bradycardia
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Blood pressure increased
|
Blood pressure increased
|
postmarketing, 0.4%
|
|
|
x
|
x
|
x
|
|
|
|
Face oedema
|
Face oedema
|
postmarketing
|
|
|
x
|
x
|
x
|
|
|
x
|
Presyncope
|
Presyncope
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Phlebitis superficial
|
Phlebitis superficial
|
postmarketing
|
|
|
|
|
|
x
|
|
|
Oropharyngeal swelling
|
Oropharyngeal swelling
|
postmarketing
|
|
|
x
|
x
|
|
|
|
|
Parosmia
|
Parosmia
|
postmarketing, 0.3%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Nephrogenic systemic fibrosis
|
Nephrogenic systemic fibrosis
|
postmarketing
|
|
x
|
x
|
x
|
x
|
|
x
|
|
Amblyopia
|
Amblyopia
|
|
|
|
|
|
|
|
|
x
|
Decreased appetite
|
Anorexia
|
|
|
|
|
|
|
|
|
x
|
Anxiety
|
Anxiety
|
|
|
|
|
|
|
x
|
|
x
|
Arthralgia
|
Arthralgia
|
|
|
|
|
|
|
|
|
x
|
Musculoskeletal discomfort
|
Arthralgia
|
|
|
|
|
|
|
|
|
x
|
Myalgia
|
|
|
|
|
|
|
|
x
|
x
|
Asthma
|
Asthma
|
|
|
|
|
|
|
|
|
x
|
Bundle branch block
|
Bundle branch block
|
|
|
|
|
|
x
|
|
|
|
Neck pain
|
Neck pain
|
|
|
|
|
|
|
|
|
x
|
Confusional state
|
Confusional state
|
|
|
|
|
|
|
|
|
x
|
Constipation
|
Constipation
|
|
|
|
|
|
|
|
|
x
|
Dysphagia
|
Dysphagia
|
|
|
|
|
|
|
|
|
x
|
Depersonalisation
|
Depersonalisation
|
|
|
|
|
|
|
|
|
x
|
Diplopia
|
Diplopia
|
|
|
|
|
|
|
|
|
x
|
Dysuria
|
Dysuria
|
|
|
|
|
|
|
|
|
x
|
Epistaxis
|
Epistaxis
|
|
|
|
|
|
|
|
|
x
|
Eructation
|
Eructation
|
|
|
|
|
|
|
|
|
x
|
Erythema multiforme
|
Erythema multiforme
|
|
|
|
|
|
|
|
|
x
|
Eye disorder
|
Eye disorder
|
|
|
|
|
|
|
|
x
|
|
Flatulence
|
Flatulence
|
|
|
|
|
|
|
|
|
x
|
Glioma
|
Glioma
|
|
|
|
|
|
|
|
x
|
|
Hallucination
|
Hallucination
|
|
|
|
|
|
|
|
|
x
|
Haemoptysis
|
Haemoptysis
|
|
|
|
|
|
|
|
|
x
|
Hypercalcaemia
|
Hypercalcaemia
|
|
|
|
|
|
|
|
|
x
|
Hyperglycaemia
|
Hyperglycaemia
|
|
|
|
|
|
|
|
|
x
|
Hypertension
|
Hypertension
|
|
|
x
|
|
|
|
x
|
|
x
|
Hypoglycaemia
|
Hypoglycaemia
|
|
|
|
|
|
|
|
|
x
|
Hyponatraemia
|
Hyponatraemia
|
|
|
|
|
|
|
|
|
x
|
Inflammation
|
Inflammation
|
|
|
|
|
|
|
x
|
|
|
Eye pruritus
|
Eye pruritus
|
|
|
|
|
|
|
|
x
|
|
Muscle spasms
|
Cramps of lower extremities
|
|
|
|
|
|
|
|
|
x
|
Muscle spasms
|
|
|
|
|
|
|
|
|
x
|
Mediastinal disorder
|
Mediastinal disorder
|
|
|
|
|
|
|
|
x
|
|
Hypertonia
|
Hypertonia
|
|
|
|
|
|
|
|
|
x
|
Nasal congestion
|
Nasal congestion
|
|
|
|
|
|
|
|
x
|
|
Nervousness
|
Nervousness
|
|
|
|
|
|
|
|
|
x
|
Tension
|
Nervousness
|
|
|
|
|
|
|
|
|
x
|
Sensory loss
|
Numbness
|
|
|
|
|
|
|
|
|
x
|
Oliguria
|
Oliguria
|
|
|
|
|
|
|
|
|
x
|
Pain in extremity
|
Pain in extremity
|
|
|
|
|
|
|
x
|
|
|
Palpitations
|
Palpitations
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
Pelvic pain
|
Pelvic pain
|
|
|
|
|
|
|
|
|
x
|
Pharyngitis
|
Pharyngitis
|
|
|
|
|
|
|
|
|
x
|
Hyperacusis
|
Hyperacusis
|
|
|
|
|
|
|
|
|
x
|
Sinusitis
|
Sinusitis
|
|
|
|
|
|
|
|
|
x
|
Thirst
|
Thirst
|
|
|
|
|
|
|
|
|
x
|
Thrombocytopenia
|
Thrombocytopenia
|
|
|
|
|
|
|
|
|
x
|
Thrombophlebitis
|
Thrombophlebitis
|
|
|
|
|
|
|
|
|
x
|
Tinnitus
|
Tinnitus
|
|
|
|
|
|
|
|
|
x
|
Wheezing
|
Wheezing
|
|
|
|
|
|
|
|
x
|
|
Atrioventricular block first degree
|
Atrioventricular block first degree
|
|
|
|
|
|
|
|
x
|
|
Vasospasm
|
Vasospasm
|
|
|
|
|
|
|
|
|
x
|
Musculoskeletal stiffness
|
Neck stiffness
|
|
|
|
|
|
|
|
|
x
|
Nuchal rigidity
|
Neck stiffness
|
|
|
|
|
|
|
|
|
x
|
Application site reaction
|
Application site reaction
|
|
|
|
|
|
|
|
|
x
|
Blood creatinine increased
|
Creatinine increased
|
|
|
|
|
|
|
|
|
x
|
Serum creatinine increased
|
|
|
|
|
|
|
x
|
|
|
Swelling face
|
Swelling face
|
|
|
|
|
|
|
|
x
|
|
Injection site swelling
|
Injection site swelling
|
|
|
|
|
|
|
|
|
x
|
Tongue disorder
|
Tongue oedema
|
|
|
|
|
|
|
|
x
|
|
Tongue oedema
|
Tongue oedema
|
|
|
|
|
|
|
|
x
|
|
Injection site inflammation
|
Injection site inflammation
|
|
|
|
|
|
|
|
|
x
|
Dry skin
|
Dry skin
|
|
|
|
|
|
|
|
|
x
|
Rash macular
|
Rash macular
|
|
|
|
|
|
|
|
|
x
|
Myalgia
|
Myalgia
|
|
|
|
|
|
|
|
x
|
x
|
Increased appetite
|
Increased appetite
|
|
|
|
|
|
|
|
|
x
|
Lip swelling
|
Lip swelling
|
|
|
|
|
|
|
|
x
|
|
Pancreatitis necrotising
|
Pancreatitis necrotising
|
|
|
|
|
|
|
|
x
|
|
Eye swelling
|
Eye swelling
|
|
|
|
|
|
|
|
x
|
|
Akathisia
|
Akathisia
|
|
|
|
|
|
x
|
|
|
|
Oral discomfort
|
Oral discomfort
|
|
|
|
|
|
x
|
|
|
|
Rash maculo-papular
|
Rash maculo-papular
|
|
|
|
|
|
x
|
|
|
|
Injection site haemorrhage
|
Injection site bruising
|
|
|
x
|
|
|
|
|
|
|
Injection site bruising
|
Injection site bruising
|
|
|
x
|
|
|
|
|
|
|
Paraesthesia oral
|
Paraesthesia oral
|
|
|
|
|
|
|
|
x
|
|
Visual impairment
|
Visual disturbance
|
|
|
|
|
|
|
|
x
|
|
Basophilia
|
Basophilia
|
|
|
|
|
|
|
|
x
|
|
Vessel puncture site bruise
|
Venipuncture site bruise
|
|
|
x
|
|
|
|
|
|
|
Oropharyngeal discomfort
|
Oropharyngeal discomfort
|
|
|
|
|
|
|
x
|
|
|
Renal failure acute
|
Acute kidney injury
|
|
|
|
|
|
|
x
|
|
|
Somnolence
|
Somnolence
|
|
|
|
|
|
|
x
|
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 15 |
Source: | FDA Structured Product Label |
---|
Side effects: | 43 |
Source: | FDA Structured Product Label |
---|
Side effects: | 44 |
Source: | FDA Structured Product Label |
---|
Side effects: | 52 |
Source: | FDA Structured Product Label |
---|
Side effects: | 62 |
Source: | FDA Structured Product Label |
---|
Side effects: | 62 |
Source: | FDA Structured Product Label |
---|
Side effects: | 89 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|