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Diltiazem

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: C08DB01

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 37 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Oedema peripheral Edema of lower extremities postmarketing, 3.78% - 8.13% 3.33% x x x x x x x
Oedema peripheral 2% - 5% x
Headache Headache 2.1% - 17% 2% - 13.8% x x x x x x x x x x x x x x x x x x x
Asthenia Fatigue 4.8% x x x x x
Asthenia 0.6% - 6% 0% - 4% x x x x x x x x x x x x x x x x x x
Fatigue Fatigue 4.8% x x x x x
Oedema Oedema 1.9% - 14.6% 0% - 2% x x x x x x x x x x x x x x x x x x x x
Pain Pain 0.99% - 6.33% 0% - 2.3% x x x x x x x x
Dizziness Dizziness 1.5% - 10.2% 0% - 7.02% x x x x x x x x x x x x x x x x x x x
Syncope x x x x x x x x x x x x x x x x x x x
Lightheadedness x
Sinus bradycardia Sinus bradycardia 3% x
Nasopharyngitis Nasopharyngitis 2.94% x
Atrioventricular block first degree Atrioventricular block first degree 1.8% - 3.3% 0% x x x x x x x x x x x x x x x
Bronchitis Bronchitis 0.633% - 4.08% 0% x x x x
Vasodilation procedure Vasodilation postmarketing, 1% - 3.36% 1.75% x x x x x x x x
Cough Cough 1.27% - 2.97% 0% - 2.3% x x x x x x x x x
Influenza Influenza 0% - 2.31% 0% - 1.15% x x x
Myalgia Myalgia postmarketing, 0% - 2.31% 0% x x x x x
Musculoskeletal discomfort Myalgia postmarketing, 0% - 2.31% 0% x x x x x
Arthralgia 1.44% 0% x
Pharyngitis Pharyngitis 1.44% - 6.25% 2% - 4.6% x x x x
Palpitations Palpitations 1.2% - 2.08% 0% - 0.948% x x x x x x x x x x x x x x x x x x x
Rhinitis Rhinitis 1% - 9.57% 2% - 8.05% x x x x x x x
Diarrhoea Diarrhoea 1.34% - 2.08% 0% x x x x x x x x x x x x x x x x x x x
Sinusitis Sinusitis 1.98% - 2.94% 1.15% x
Vomiting Vomiting 1.98% 0% x x x x x x x x x x x x x x x x x x x x
Bradycardia Bradycardia postmarketing, 1.44% - 6.03% 0% - 1.42% x x x x x x x x x x x x x x
Atrioventricular block Atrioventricular block 0% - 4.08% 0% x x x x x x x x x x x x x x x x x x x x
Block heart postmarketing x
Nervousness Nervousness 0% - 2.01% 0% x x x x x x x x x x x x x x x x x x
Feeling jittery x
Tension Nervousness 0% - 2.01% 0% x x x x x x x x x x x x x x x x x x
Paraesthesia Paraesthesia 1% - 2% x x x x x x x x x x x x x x x x x x x
Tachycardia Tachycardia 1% - 2% x x x x x x x x x x x x x x x x x x
Arthralgia Arthralgia 1.44% 0% x
Cardiac fibrillation Cardiac fibrillation 1.44% 0% x
Flushing Flushing postmarketing, 1.4% - 3% x x x x x x x x x x x x x x
Nausea Nausea 1.27% - 5% 0% - 1.15% x x x x x x x x x x x x x x x x x x x
Constipation Constipation 1% - 3.63% 0.948% - 2.3% x x x x x x x x x x x x x x x x x x
Infection Infection 0.6% - 6.25% 0% - 3.51% x x x x x x
Somnolence Somnolence 1.27% x x x x x x x x x x x x x x x x x x x
Dyspepsia Dyspepsia 0% - 6.12% 0% - 0.474% x x x x x x x x x x x x x x x x
Gout Gout 1.2% - 2.04% 0% x x x x x
Albuminuria Albuminuria 1.2% x x x x x x x
Arrhythmia Arrhythmia 1.2% x
Dermatitis Rash postmarketing, 0% - 2.04% 0% - 1.15% x x x x x x x x x x x x x x x x x x
Dermatitis x
Rash Rash postmarketing, 0% - 2.04% 0% - 1.15% x x x x x x x x x x x x x x x x x x
Hyperglycaemia Hyperglycaemia 1.2% x x x x x x x x x x x x x x x x x x
Crystalluria Crystalluria 1.2% x x x x x x x
Conjunctivitis Conjunctivitis 0% - 2.04% 0% x x x
Erectile dysfunction Erectile dysfunction 0% - 2.04% 0% x x x x x x x x x x x x x x x x x x x
Extrasystoles Extrasystoles 0% - 2.04% 0% x x x x
Abdominal distension Enlargement abdomen 0% - 2.04% 0% x x x
Sinus congestion Sinus congestion 0.399% - 1.63% 0% x x x
Decreased appetite Anorexia 1% x x x x x x x x x x x x x x x x x x x
Dyspnoea Dyspnoea 0.6% - 6.12% 0% x x x x x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity 1% x x x x x x x x x x x x x x x
Polyuria Polyuria 1% - 1.27% 0.948% x x x x x x x x x x x x x x x x x x
Urine output increased Polyuria 1% - 1.27% 0.948% x x x x x x x x x x x x x x x x x x
Dry mouth Dry mouth 1% x x x x x x x x x x x x x x x x x x x
Musculoskeletal stiffness Neck stiffness 1% x x x x x x x x
Nuchal rigidity Neck stiffness 1% x x x x x x x x
Arthropathy Arthropathy 0.99% 0%
Osteoarthritis Arthropathy 0.99% 0%
Tinnitus Tinnitus 0.99% 0% x x x x x x x x x x x x x x x x x x x
Insomnia Insomnia 0.952% - 0.99% 0% - 0.474% x x x x x x x x x x x x x x x x x x
Hypotension Hypotension 0.952% 0.474% x x x x x x x x x x x x x x x x x x x
Hypotension asymptomatic x
Hypotension symptomatic x
Agranulocytosis Agranulocytosis postmarketing x
Alopecia Alopecia postmarketing x x x x x x x x x x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia postmarketing x x x x x x x x x x x x x x x x x x
Angioedema Angioedema postmarketing x x x x x x x x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative postmarketing x x x x x x x x x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis postmarketing x x x x x x x x x x x x x x x x x x x
Necrolysis epidermal x
Erythema multiforme Erythema multiforme postmarketing x x x x x x x x x x x x x x x x x x
Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased postmarketing x x x x
Gingival hyperplasia Gingival hyperplasia postmarketing x x x x x x x x x x x x x x x x x x
Gynaecomastia Gynaecomastia postmarketing x x x x x x x x
Orthostatic hypotension Orthostatic hypotension postmarketing x x x x
Leukopenia Leukopenia postmarketing x x x x x x x x x x x x x x x x x x
Myocardial infarction Myocardial infarction postmarketing x x x x x x x x x x x x x x x x x x x
Acute coronary syndrome Myocardial infarction postmarketing x x x x x x x x x x x x x x x x x x x
Purpura Purpura postmarketing x x x x x x x x x x x x x x x x x x
Vascular purpura Purpura postmarketing x x x x x x x x x x x x x x x x x x
Retinal disorder Retinal disorder postmarketing x x x x x x x x x x x x x x x x x x
Sinoatrial block Sinoatrial block postmarketing x x x
Device capturing issue Sinoatrial block postmarketing x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x x x
Hyperhidrosis Sweating postmarketing x x x x x
Thrombocytopenia Thrombocytopenia postmarketing x x x x x x x x x x x x x x x x x x
Erythema Erythema postmarketing x x x x
Vasculitis Vasculitis postmarketing x x x
Rash pustular Rash pustular postmarketing x x x
Leukocytoclastic vasculitis Allergic cutaneous angiitis postmarketing x
Leukocytoclastic vasculitis x x x x x x x x x x x x x x x x x
Bleeding time prolonged Bleeding time prolonged postmarketing x x x x x x x x x x x x x x x x x x
Abdominal pain Stomach ache postmarketing x x x
Abdominal pain upper Stomach ache postmarketing x x x
Malaise Malaise postmarketing x x x x
Discomfort Malaise postmarketing x x x x
Feeling abnormal Malaise postmarketing x x x x
Ill-defined disorder Malaise postmarketing x x x x
Extrapyramidal disorder Extrapyramidal symptoms postmarketing x x x x x x x x x x x x x x x x x x
Extrapyramidal disorder x x
Visual impairment Abnormal vision postmarketing x
Amblyopia Amblyopia x x x x x x x x x x x x x x x x x x x
Amnesia Amnesia x x x x x x x x x x x x x x x x x x
Bundle branch block Bundle branch block x x x x x x x x x x x x x x x x
Bursitis Bursitis x
Neck pain Neck pain x
Chest pain Chest pain x x
Colitis Colitis x
Cystitis Cystitis x
Bladder pain Cystitis x
Cystitis noninfective Cystitis x
Dermatitis contact Dermatitis contact x
Diplopia Diplopia x
Dysgeusia Dysgeusia x x x x x x x x x x x x x x x x x x x
Dysmenorrhoea Dysmenorrhoea x
Ear pain Ear pain x
Ecchymosis Ecchymosis x x
Endophthalmitis Endophthalmitis x
Panophthalmitis Endophthalmitis x
Epistaxis Epistaxis x x x x x x x x x x x x x x x x x x x
Eructation Eructation x
Eye disorder Eye disorder x
Eye haemorrhage Eye haemorrhage x
Flatulence Flatulence x
Vitreous floaters Vitreous floaters x
Cardiac flutter Cardiac flutter x
Gastrointestinal disorder Gastrointestinal disorder x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x
Hallucination Hallucination x x x x x x x x x x x x x x x x x x
Cardiac arrest Cardiac arrest x x x x x x x x x x
Cardiac disorder Cardiac disorder x
Cardiac failure congestive Cardiac failure congestive x x x x x x x x x x x x x x x x x x
Hepatitis Hepatitis x x x
Nephrolithiasis Calculus of kidney x
Lethargy Lethargy x
Mediastinal disorder Mediastinal disorder x
Muscle spasms Cramp muscle x x x x x x x x x x x x x x x x
Hypertonia Hypertonia x
Myopathy Myopathy x x x x
Nasal congestion Nasal congestion x x x x x x x x x x x x x x x x x x
Nervous system disorder Nervous system disorder x
Melanocytic naevus Nevus x
Nocturia Nocturia x x x x x x x x x x x x x x x x x x
Otitis media Otitis media x
Pallor Pallor x
Petechiae Petechiae x x x x x x x x x x x x x x x x x x
Phlebitis Phlebitis x
Prostatic disorder Prostatic disorder x
Pruritus Pruritus x x x x x x x x x x x x x x x x x x x
Pyelonephritis Pyelonephritis x
Renal failure Renal failure x
Sinus headache Sinus headache x
Gastric ulcer Gastric ulcer x
Swelling Swelling x x x
Shock Syncope x x x x x x x x x x x x x x x x x x x
Syncope Syncope x x x x x x x x x x x x x x x x x x x
Loss of consciousness Syncope x x x x x x x x x x x x x x x x x x x
Thirst Thirst x x x x x x x x x x x x x x x x x x
Tooth disorder Tooth disorder x
Tremor Tremor x x x x x x x x x x x x x x x x x x
Pollakiuria Pollakiuria x
Urinary tract infection Urinary tract infection x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x x x x x x x x x x x
Vaginal inflammation Vaginal inflammation x
Vaginal infection Vaginal inflammation x
Angiopathy Angiopathy x
Ventricular fibrillation Ventricular fibrillation x
Ventricular tachycardia Ventricular tachycardia x
Vertigo Vertigo x x
Weight increased Weight increased x x x x x x x x x x x x x x x x x x x
Ventricular arrhythmia Ventricular arrhythmia x
Mood swings Mood swings x x
Affect lability Mood swings x x
Dissociation Dissociation x
Periorbital oedema Periorbital oedema x x x x x x x x x
Atrioventricular block complete Atrioventricular block complete
Blood creatine phosphokinase increased Creatine phosphokinase increased x x x x x x x x x x x x x
Ventricular extrasystoles Ventricular extrasystoles x x x x x x x x x x x x x x x x x x x
Skin hypertrophy Skin hypertrophy x
Injection site reaction Injection site reaction x
Injury Accidental injury x
Myocardial ischaemia Myocardial ischaemia x
Bone pain Bone pain x
Aspartate aminotransferase increased Aspartate aminotransferase increased x x
Joint swelling Joint swelling x
Malnutrition Malnutrition x
Skin hyperpigmentation Skin hyperpigmentation x x x
Nodal rhythm Nodal rhythm x
Thinking abnormal Thinking abnormal x
Mental disability Thinking abnormal x
Abnormal dreams Abnormal dreams x x x x x x x x x x x x x x x x x x
Eye irritation Eye irritation x x x x x x x x x x x x x x x x x x
Personality change Personality change x x x x x x x x x x x x x x x x x x
Left ventricular dysfunction Left ventricular dysfunction x
Atrioventricular block second degree Atrioventricular block second degree x
Parkinsonism Drug-induced parkinsonism
Vision blurred Vision blurred x
Photosensitivity reaction Photosensitivity x x x x x x x x x x x x x x x x x x
Sinus arrhythmia Sinoatrial node dysfunction x
Neuropathy peripheral Neuropathy x
Respiratory distress Respiratory distress x
Lymphadenopathy Lymphadenopathy x
Rash generalised Rash generalised x x x x x x x x x x x x x x
Electrocardiogram ST segment elevation Electrocardiogram ST segment elevation x
Sinus arrest Sinus arrest x
Face oedema Face oedema x
Feeling jittery Feeling jittery x
Gait disturbance Gait disturbance x x x x x x x x x x x x x x x x x x
Local swelling Neck swelling x
Peripheral swelling x
Blood uric acid increased Hyperuricaemia x x x x x x x x x x x x x x x x x x
Hyperuricaemia Hyperuricaemia x x x x x x x x x x x x x x x x x x
Liver injury Acute liver damage x x x x x
Acute liver injury x x x x x
Acute generalised exanthematous pustulosis Acute generalised exanthematous pustulosis x x x
Abdominal discomfort Gastrointestinal discomfort x
Lichenoid keratosis Lichenoid keratosis x x x
Musculoskeletal pain Osteoarticular pain x x x x x x x x x x x x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

DILZEM / Dilzem, Film coated tablet

Side effects:18
Source:Medsafe

DILTIAZEM

Side effects:71
Source:FDA Structured Product Label

Diltiazem

Side effects:72
Source:FDA Structured Product Label

DILTIAZEM

Side effects:73
Source:FDA Structured Product Label

DILTIAZEM

Side effects:73
Source:FDA Structured Product Label

Diltiazem

Side effects:77
Source:FDA Structured Product Label

DILTIAZEM

Side effects:78
Source:FDA Structured Product Label

DILTIAZEM

Side effects:80
Source:FDA Structured Product Label

diltiazem hydrochloride / Cardizem LA

Side effects:81
Source:FDA

Diltiazem hydrochloride / Coras

Side effects:82
Source:medicines.org.au

DILTIAZEM HYDROCHLORIDE / CARDIZEM LA

Side effects:83
Source:FDA

Diltiazem

Side effects:84
Source:FDA Structured Product Label

Diltiazem hydrochloride / CARDIZEM CD

Side effects:84
Source:medicines.org.au

DILTIAZEM

Side effects:85
Source:FDA Structured Product Label

Diltiazem

Side effects:85
Source:FDA Structured Product Label

diltiazem hydrochloride / Tiazac

Side effects:85
Source:FDA

Diltiazem hydrochloride / DILTIAZEM CD CAPSULES

Side effects:86
Source:medicines.org.au

DILTIAZEM

Side effects:90
Source:FDA Structured Product Label

DILTIAZEM HYDROCHLORIDE / TIAZAC XC

Side effects:98
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label