Side effect information for Conjugated estrogens

Side effects

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MedDRA Preferred Term	Side effect	Data for drug	Placebo	Labels
				1	2	3	4	5	6	7	8	9
Pruritus	Pruritus	postmarketing, 0.714% - 5.03%	0% - 2.11%		x	x	x	x	x	x	x	x
Breast pain	Breast pain	2.14% - 4.9%	0% - 4.17%		x		x	x	x	x	x	x
Vulvovaginal disorder	Vulvovaginal disorder	2.14% - 2.8%	0% - 2.94%		x
Vasodilation procedure	Vasodilation	1.43% - 2.1%	0% - 2.78%		x
Candida infection	Candida infection	0.714% - 1.4%	0% - 1.39%		x
Vaginal haemorrhage	Vaginal haemorrhage	0.714% - 1.4%	0% - 1.47%		x		x	x	x	x	x	x
Acne	Acne	0% - 1.43%	0%		x
Dysuria	Dysuria	0% - 1.4%	0%	x	x
Muscle spasms	Cramp muscle	0% - 1.4%	0%	x	x
Muscle spasms	Cramps of lower extremities	postmarketing			x	x	x	x	x	x	x	x
Pollakiuria	Micturition urgency	0% - 0.699%	0% - 1.39%		x
Pollakiuria	Pollakiuria	0%	0% - 1.39%		x
Micturition urgency	Micturition urgency	0% - 0.699%	0% - 1.39%		x
Breast enlargement	Breast enlargement	0% - 0.699%	0% - 1.39%	x	x
Abdominal pain	Abdominal cramps	postmarketing			x	x	x	x	x		x	x
Abdominal pain	Abdominal pain	postmarketing	9.72%	x	x		x	x	x	x	x	x
Gastrointestinal pain	Abdominal pain	postmarketing	9.72%	x	x		x	x	x	x	x	x
Arthralgia	Arthralgia	postmarketing			x	x	x	x	x	x	x	x
Musculoskeletal discomfort	Arthralgia	postmarketing			x	x	x	x	x	x	x	x
Musculoskeletal discomfort	Myalgia									x	x	x
Breast cancer	Breast cancer	postmarketing			x					x
Vulvovaginal candidiasis	Vaginal moniliasis	postmarketing, 0% - 1.4%	0%		x	x	x	x	x	x	x	x
Vulvovaginal mycotic infection	Vaginal moniliasis	postmarketing, 0% - 1.4%	0%		x	x	x	x	x	x	x	x
Cystitis	Cystitis	postmarketing		x	x
Bladder pain	Cystitis	postmarketing		x	x
Cystitis noninfective	Cystitis	postmarketing		x	x
Depression	Depression	postmarketing		x	x	x	x	x	x	x	x	x
Dizziness	Dizziness	postmarketing, 0% - 0.699%	0% - 4.17%	x	x	x	x	x	x	x	x	x
Dizziness	Syncope			x
Dysmenorrhoea	Dysmenorrhoea	postmarketing	2.78%	x	x	x	x	x	x	x	x	x
Oedema	Oedema	postmarketing		x	x	x	x	x	x	x	x	x
Endometrial hyperplasia	Endometrial hyperplasia	postmarketing			x	x	x	x	x	x	x	x
Epilepsy	Epilepsy	postmarketing				x	x	x	x	x	x	x
Erythema multiforme	Erythema multiforme	postmarketing		x		x	x	x	x	x	x	x
Erythema nodosum	Erythema nodosum	postmarketing		x		x	x	x	x	x	x	x
Dermatitis	Rash	postmarketing			x	x	x	x	x	x	x	x
Rash	Rash	postmarketing			x	x	x	x	x	x	x	x
Fibrocystic breast disease	Fibrocystic breast disease	postmarketing			x	x	x	x	x	x	x	x
Gallbladder disorder	Gallbladder disorder	postmarketing		x	x	x	x	x	x	x	x	x
Gynaecomastia	Gynaecomastia	postmarketing			x					x
Headache	Headache	postmarketing, 2.14% - 3.5%	1.39% - 20.8%	x	x	x	x	x	x	x	x	x
Haemangioma	Haemangioma	postmarketing				x	x	x	x	x	x	x
Hirsutism	Hirsutism	postmarketing		x	x	x	x	x	x	x	x	x
Hypersensitivity	Hypersensitivity	postmarketing			x					x
Irritability	Irritability	postmarketing		x	x		x	x	x	x	x	x
Jaundice cholestatic	Jaundice cholestatic	postmarketing		x		x	x	x	x	x	x	x
Vaginal discharge	Leukorrhea	postmarketing, 2.1% - 2.86%	1.39% - 7.35%		x					x	x	x
Chloasma	Chloasma	postmarketing		x	x	x	x	x	x	x	x	x
Myocardial infarction	Myocardial infarction	postmarketing			x	x	x	x	x	x	x	x
Acute coronary syndrome	Myocardial infarction	postmarketing			x	x	x	x	x	x	x	x
Nausea	Nausea	postmarketing	8.33%	x	x	x	x	x	x	x	x	x
Nervousness	Nervousness	postmarketing		x	x	x	x	x	x	x	x	x
Tension	Nervousness	postmarketing		x	x	x	x	x	x	x	x	x
Pain	Pain	postmarketing, 0.714% - 1.4%	0% - 8.33%		x					x
Pancreatitis	Pancreatitis	postmarketing				x	x	x	x	x	x	x
Pelvic pain	Pelvic pain	postmarketing, 2.8% - 2.86%	0% - 2.78%		x	x				x	x	x
Porphyrin metabolism disorder	Porphyrin metabolism disorder	postmarketing				x	x	x	x	x	x	x
Pruritus genital	Pruritus genital	postmarketing			x
Precocious puberty	Precocious puberty	postmarketing			x
Pulmonary embolism	Pulmonary embolism	postmarketing			x	x	x	x	x	x	x	x
Cerebrovascular accident	Cerebrovascular accident	postmarketing			x	x	x	x	x	x	x	x
Thrombophlebitis	Thrombophlebitis	postmarketing		x		x	x	x	x	x	x	x
Urticaria	Urticaria	postmarketing			x	x	x	x	x	x	x	x
Uterine leiomyoma	Uterine leiomyoma	postmarketing			x	x	x	x	x	x	x	x
Uterine haemorrhage	Uterine haemorrhage	postmarketing			x					x
Vaginal inflammation	Vaginal inflammation	postmarketing, 1.4% - 2.14%	1.39% - 4.41%		x	x	x	x	x	x	x	x
Vaginal infection	Vaginal inflammation	postmarketing, 1.4% - 2.14%	1.39% - 4.41%		x	x	x	x	x	x	x	x
Vomiting	Vomiting	postmarketing		x	x	x	x	x	x	x	x	x
Deep vein thrombosis	Deep vein thrombosis	postmarketing			x
Migraine	Migraine	postmarketing, 0%	0% - 1.47%	x	x	x	x	x	x	x	x	x
Colitis ischaemic	Colitis ischaemic	postmarketing				x				x	x	x
Tenderness	Tenderness	postmarketing		x	x	x		x	x	x	x	x
Thrombophlebitis superficial	Superficial phlebothrombosis	postmarketing				x	x	x	x	x	x	x
Galactorrhoea	Galactorrhoea	postmarketing				x	x	x	x	x	x	x
Glucose tolerance impaired	Glucose tolerance impaired	postmarketing			x	x				x	x	x
Meningioma benign	Meningioma benign	postmarketing				x				x	x	x
Asthma	Exacerbation of asthma	postmarketing			x	x	x	x	x	x	x	x
Endometrial cancer	Endometrial cancer	postmarketing			x	x	x	x	x	x	x	x
Blood pressure increased	Blood pressure increased	postmarketing		x	x	x	x	x	x	x	x	x
Dementia	Dementia	postmarketing			x	x	x	x	x	x	x	x
Vulvovaginal discomfort	Vulvovaginal discomfort	postmarketing			x
Retinal vascular thrombosis	Retinal vascular thrombosis	postmarketing			x	x	x	x	x	x	x	x
Ovarian cancer	Ovarian cancer	postmarketing				x	x	x	x	x	x	x
Abdominal distension	Abdominal bloating	postmarketing		x	x	x	x	x	x	x	x	x
Flatulence	Abdominal bloating	postmarketing		x	x	x	x	x	x	x	x	x
Flatulence	Flatulence		2.78%				x	x	x	x	x	x
Mood swings	Mood alteration NOS	postmarketing			x		x	x	x	x	x	x
Anaphylactic shock	Anaphylactic shock						x	x	x		x	x
Angioedema	Angioedema						x	x	x		x	x
Asthenia	Asthenia									x	x	x
Asthenia	Fatigue			x
Back pain	Back pain									x	x	x
Coagulopathy	Clotting			x
Breast swelling	Breast swelling			x
Bronchitis	Bronchitis		4.17%				x	x	x
Neoplasm malignant	Neoplasm malignant			x	x
Cardiovascular disorder	Cardiovascular disorder				x
Uterine cervical erosion	Uterine cervical erosion			x
Chorea	Chorea					x	x	x	x		x	x
Infection	Infection									x	x	x
Coronary artery thrombosis	Coronary artery thrombosis			x
Diarrhoea	Diarrhoea									x	x	x
Dyspepsia	Dyspepsia									x	x	x
Dyspnoea	Dyspnoea			x
Endometriosis	Endometriosis			x
Epistaxis	Epistaxis			x
Fatigue	Fatigue			x
Hyperglycaemia	Hyperglycaemia			x
Hypernatraemia	Hypernatraemia			x
Hypocalcaemia	Hypocalcaemia					x	x	x	x		x	x
Influenza	Influenza		4.17%				x	x	x	x	x	x
Jaundice	Jaundice			x
Pain in extremity	Leg pain			x
Hepatic neoplasm	Hepatic neoplasm			x
Menorrhagia	Menorrhagia			x
Metrorrhagia	Metrorrhagia	0%	0% - 2.94%	x	x		x	x	x
Metrorrhagia	Bleeding breakthrough			x			x	x	x
Musculoskeletal pain	Musculoskeletal pain			x
Neuritis	Neuritis			x
Neuropathy peripheral	Neuritis			x
Hypoaesthesia	Numbness			x
Sensory loss	Numbness			x
Optic neuritis	Optic neuritis			x
Palpitations	Palpitations			x
Paraesthesia	Paraesthesia		0%				x	x	x
Pharyngitis	Pharyngitis									x	x	x
Phlebitis	Phlebitis					x
Rhinitis	Rhinitis		5.56%				x	x	x	x	x	x
Sinusitis	Sinusitis		2.78%				x	x	x	x	x	x
Swelling	Swelling			x
Shock	Syncope			x
Syncope	Syncope			x
Loss of consciousness	Syncope			x
Embolism	Thromboembolism			x
Embolism venous	Thromboembolism			x
Thrombosis	Thrombosis			x
Erythema	Erythema	0%	0% - 1.39%		x
Upper respiratory tract infection	Upper respiratory tract infection									x	x	x
Urinary tract infection	Urinary tract infection	0%	0% - 1.39%		x
Vulvovaginal pruritus	Vaginal itching			x
Varicose vein	Varicose vein			x
Hepatic function abnormal	Hepatic function abnormal			x
Breast discharge	Breast discharge						x	x	x
Injection site swelling	Injection site swelling					x
Glucose tolerance decreased	Glucose tolerance decreased			x
Injury	Accidental injury		6.94%				x	x	x	x	x	x
Injection site pain	Injection site pain					x
Skin irritation	Skin irritation			x
Myalgia	Myalgia									x	x	x
Abdominal discomfort	Abdominal discomfort			x
Abdominal pain upper	Abdominal pain upper			x
Abdominal pain lower	Abdominal pain lower			x
Purpura	Dermatitis hemorrhagic			x		x	x	x	x		x	x
Breast tenderness	Breast tenderness			x			x
Fluid retention	Fluid retention			x
Ectropion of cervix	Ectropion of cervix					x	x	x	x		x	x
Increased tendency to bruise	Increased tendency to bruise			x
Pre-existing disease	Pre-existing disease					x					x	x
Visual impairment	Visual disturbance			x
Cough	Cough increased									x	x	x
Mass	Mass			x
Breast discomfort	Breast discomfort			x
Insomnia	Insomnia									x	x	x
Abnormal withdrawal bleeding	Abnormal withdrawal bleeding						x	x	x

Indication	Labels
Angiopathy	x
Atrophy		x		x	x		x	x	x
Atrophy of vulva	x
Breast cancer	x						x	x	x
Breast feeding	x
Carcinoma	x
Cerebrovascular accident	x
Dyspareunia		x
Endometrial cancer	x
Endometrial hyperplasia	x
Fracture	x
Genital haemorrhage	x
Hot flush	x
Hypogonadism	x						x	x	x
Imbalance hormonal			x
Inflammation	x
Liver disorder	x
Menopausal symptoms	x
Menopause	x	x		x	x	x	x	x	x
Metastatic disease							x	x	x
Migraine	x
Myocardial infarction	x
Neoplasm malignant	x
Oestrogen deficiency	x
Oestrogen low	x
Osteopenia	x
Osteoporosis	x
Osteoporosis postmenopausal							x	x	x
Pain				x	x
Postmenopausal syndrome	x
Premenopause	x
Primary ovarian failure	x						x	x	x
Prostate carcinoma							x	x	x
Pruritus	x
Surgical menopause	x
Sweating	x
Thrombophlebitis	x
Unspecified visual loss	x
Uterine haemorrhage			x
Vaginal dryness				x	x
Vaginal haemorrhage	x
Vaginitis atrophic	x	x
Vulval leukoplakia		x
Warmth	x

Side effects:	66
Source:	Health Canada

Side effects:	65
Source:	FDA Structured Product Label

Side effects:	56
Source:	FDA Structured Product Label

Side effects:	66
Source:	FDA Structured Product Label

Search results :

Conjugated estrogens

Side effects

Indications

CONJUGATED ESTROGENS / PMS-CONJUGATED ESTROGENS C.S.D.

ESTROGENS, CONJUGATED

ESTROGENS, CONJUGATED

ESTROGENS, CONJUGATED SYNTHETIC B

ESTROGENS, CONJUGATED SYNTHETIC B / ENJUVIA

ESTROGENS, CONJUGATED SYNTHETIC B / ENJUVIA

ESTROGENS, CONJUGATED

ESTROGENS, CONJUGATED

ESTROGENS, CONJUGATED

Color scheme:

		100%
		75%
		50%
		10%
		frequent (1% to 100%)
		infrequent (0.1% to 1%)
		rare (<0.1%)
		postmarketing
		0%
		no frequency information
		not found on label