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Maprotiline

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N06AA21

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Dry mouth Dry mouth 22% x x
Somnolence Drowsiness 16% x
Somnolence x
Dizziness Dizziness 8% x x
Syncope x x
Constipation Constipation 6% x x
Nervousness Nervousness 6% x x
Tension Nervousness 6% x x
Asthenia Fatigue 4% x x
Asthenia x
Fatigue Fatigue 4% x x
Headache Headache 4% x x
Vision blurred Vision blurred 4% x x
Anxiety Anxiety 3% x
Tremor Tremor 3% x x
Nausea Nausea 2% x x
Agitation Agitation 2% x x
Hyperkinesia x
Insomnia Insomnia 2% x x
Eosinophilia Eosinophilia postmarketing x x
Toxic epidermal necrolysis Toxic epidermal necrolysis postmarketing x x
Erythema multiforme Stevens-Johnson syndrome postmarketing x x
Erythema multiforme x
Stevens-Johnson syndrome Stevens-Johnson syndrome postmarketing x x
Interstitial lung disease Interstitial pneumonia postmarketing x
Abdominal pain Abdominal cramps x
Abdominal pain x
Gastrointestinal pain Abdominal pain x
Lymphadenitis Adenitis x
Aggression Aggression x
Agranulocytosis Agranulocytosis x x
Alopecia Alopecia x x
Alveolitis allergic Alveolitis allergic x
Arrhythmia Arrhythmia x x
Ataxia Ataxia x x
Bone disorder Bone disorder x
Breast disorder Breast disorder x
Bronchospasm Bronchospasm x
Bundle branch block Bundle branch block x
Infection Infection x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Libido decreased Libido decreased x
Disturbance in sexual arousal Libido decreased x
Dysphagia Dysphagia x
Delirium Delirium x
Delusion Delusion x
Dental caries Dental caries x
Depersonalisation Depersonalisation x
Dermatitis atopic Dermatitis atopic x
Diarrhoea Diarrhoea x x
Dysarthria Dysarthria x x
Osteoarthritis Dysarthria x x
Dysgeusia Dysgeusia x
Taste bitter x
Dyskinesia Dyskinesia x
Oedema Oedema x x
Endocrine disorder Endocrine disorder x
Dermatitis Rash x x
Rash Rash x x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x
Drug fever x
Flushing Flushing x
Gastrointestinal disorder Gastrointestinal disorder x
Abdominal disorder x
Gynaecomastia Gynaecomastia x
Hallucination Hallucination x x
Atrioventricular block Block heart x
Cardiac disorder Cardiac disorder x
Hepatitis Hepatitis x
Hyperhidrosis Hyperhidrosis x
Sweating increased x
Hypertension Hypertension x
Breast enlargement Hypertrophy of breast x
Breast enlargement x
Hypotension Hypotension x
Orthostatic hypotension Orthostatic hypotension x
Inappropriate antidiuretic hormone secretion Inappropriate antidiuretic hormone secretion x
Jaundice Jaundice x x
Leukopenia Leukopenia x
Mediastinal disorder Mediastinal disorder x
Mydriasis Mydriasis x
Myocardial infarction Myocardial infarction x
Acute coronary syndrome Myocardial infarction x
Myoclonus Myoclonus x
Nasal congestion Nasal congestion x x
Nervous system disorder Nervous system disorder x
Nightmare Nightmare x x
Hypoaesthesia Numbness x
Sensory loss Numbness x
Palpitations Palpitations x x
Ileus paralytic Ileus paralytic x
Paraesthesia Paraesthesia x
Tingling sensation x
Neuropathy peripheral Neuropathy peripheral x
Petechiae Petechiae x
Pruritus Pruritus x x
Psychotic disorder Psychotic disorder x x
Purpura Purpura x x
Vascular purpura Purpura x x
Convulsion Convulsion x x
Salivary hypersecretion Salivary hypersecretion x
Sleep disorder Sleep disturbance x
Sleep disorder x
Stomatitis Stomatitis x x
Cerebrovascular accident Cerebrovascular accident x
Shock Syncope x x
Syncope Syncope x x
Loss of consciousness Syncope x x
Tachycardia Tachycardia x
Sinus tachycardia Sinus tachycardia x
Thrombocytopenia Thrombocytopenia x x
Tinnitus Tinnitus x x
Torsade de pointes Torsade de pointes x
Pollakiuria Pollakiuria x
Micturition disorder Micturition disorder x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x
Angiopathy Angiopathy x
Ventricular fibrillation Ventricular fibrillation x
Ventricular tachycardia Ventricular tachycardia x
Vomiting Vomiting x x
Weight increased Weight increased x
Weight decreased Weight decreased x
Urinary retention Urinary retention x x
Depressive symptom Depressive symptom x
Drug withdrawal syndrome Withdrawal symptom x
Electroencephalogram abnormal Electroencephalogram abnormal x
Liver function test abnormal Liver function test abnormal x
Pancytopenia Bone marrow depression x
Muscular weakness Muscular weakness x
Malnutrition Malnutrition x
Photosensitivity reaction Photosensitivity reaction x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Dyspepsia Epigastric distress x
Increased appetite Increased appetite x
Disorientation Disorientation x
Derealisation Derealisation x
Memory impairment Memory impairment x
Extrapyramidal disorder Extrapyramidal symptoms x
Tongue discolouration Black hairy tongue x
Galactorrhoea Galactorrhoea x x
Hypomania Hypomania x x
Erectile dysfunction Erectile dysfunction x x
Cutaneous vasculitis Cutaneous vasculitis x
Conduction disorder Conduction disorder x
Hepatobiliary disease Hepatobiliary disease x
Mania Mania x x
Depressed mood Depressed mood x
Akathisia Akathisia x x
Hyperkinesia Hyperkinesia x
Electrocardiogram QRS complex QRS complex x
Blood pressure increased Blood pressure increased x
Coordination abnormal Coordination abnormal x
Menopausal symptoms Hot flush x
Hot flush Hot flush x
Infestation Infestation NOS x
Libido disorder Libido disorder x
Testicular swelling Testicular swelling x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

MAPROTILINE

Side effects:81
Source:FDA Structured Product Label

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label